Issue 7, 2019

Total synthesis of incargranine A

Abstract

Synthetic studies into the origins of the alkaloid incargranine A have resulted in the development of a four-step (longest linear sequence) total synthesis. This synthesis has been scaled-up to provide gram-scale quantities of material, which would alternatively require extraction of several metric-tons of dried-whole Chinese Trumpet-Creeper plants (Incarvillea mairei var. grandiflora).

Graphical abstract: Total synthesis of incargranine A

Supplementary files

Article information

Article type
Communication
Submitted
22 mar 2018
Accepted
04 apr 2018
First published
04 apr 2018
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2019,17, 1698-1702

Total synthesis of incargranine A

P. D. Brown and A. L. Lawrence, Org. Biomol. Chem., 2019, 17, 1698 DOI: 10.1039/C8OB00702K

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