A synthetic strategy involving salicylaldehyde, 2-chloroprop-2-ene-1-sulfonyl fluoride (CESF), and pyrrole has been developed to construct novel pyrrole-4H-chromene-embedded vinyl sulfonyl fluoride derivatives with exclusive regioselectivity.
We report a novel, rapid, metal-free method for vinyl ether synthesis, integrating a sulfonyl fluoride group under mild conditions in 10 min. This efficient strategy enables diverse compounds, revolutionizing industrial synthesis.
A practical and efficient method for the C-3 site selective alkenylation of indoles was developed for constructing novel indole-functionalized vinyl sulfonyl fluorides and indolyl allylic sulfonyl fluorides.
An efficient and transition metal-free method has been established for synthesizing a class of novel thiol-functionalized allylic sulfonyl fluorides with exclusive regioselectivity.
This review highlights key advances in the synthesis and biomolecular applications of sulfur(VI)-fluorides.