Application of an environmentally benign and non-toxic eutectic mixture DMU/LTA for the green synthesis of (E)-diethyl 2-arylvinylquinoline-3,4-dicarboxylates is described. A preliminary antitumor evaluation was then assayed.
The palladium-catalyzed oxidative C3-alkenylation of anthranils (2,1-benzisoxazoles) with various styrenes has been successfully achieved.
The AcONH4-promoted and catalyst-free one-pot three-component synthesis of diverse substituted 4-styrylquinazolines have been developed from 2′-aminochalcones, aromatic aldehydes/trimethyl orthoformate, and ammonium acetate.
A practical and sustainable metal-, additive-free olefination approach is proposed for the facile synthesis of various N-heteroazaarenes with high regioselectivity from simple methyl-substituted heteroarenes and amines using air as the oxidant.
Recent advances in efficient catalytic routes to olefins from alcohols (A2O) are highlighted.