Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers

Jonas Mühle, Judith Alenfelder, Matthew J. Rodrigues, Lars Jürgenliemke, Ramon Guixà-González, Lukas Grätz, Fabio Andres, Arianna Bacchin, Michael Hennig, Hannes Schihada, Max Crüsemann, Gabriele M. König, Gebhard Schertler, Evi Kostenis and Xavier Deupi

Proc. Natl. Acad. Sci. U.S.A., 2025, 122
DOI: 10.1073/pnas.2418398122