An integrative round window membrane/cochlear microphysiological system with sensing components for the study of real-time drug response

Jing Bai, Olurotimi Bolonduro, Pavlo Gordiichuk, R. Madison Green, Henry Hung-Li Chung, Ken Mahmud and Dmitry Shvartsman

Lab Chip, 2025, 25, 2744
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Biomaterials as a new option for treating sensorineural hearing loss

Liwen Wang, Ruhe Zhang, Linlan Jiang, Shuyi Gao, Jun Wu and Yuenong Jiao

Biomater. Sci., 2024, 12, 4006
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Engineering vascularized inner ear organoids: Challenges and advances in recapitulating the cochlear microenvironment

Hao Rong, Qian Zhu, Zhonghong Zhang, Xinyi Pang, Jiyang Zuo, Yusong Wang, Pan Feng, Xu Zhang, Liuying Gao, Lei Tian, Yangnan Hu, Zhisen Shen and Renjie Chai

Biomaterials, 2026, 329, 123909
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Advances in Microfluidic Cochlea‐On‐A‐Chip

Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao and Jiangang Fan

Advanced Science, 2025, 12
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Modern In Vitro Techniques for Modeling Hearing Loss

Jamie J. Shah, Couger A. Jimenez-Jaramillo, Zane R. Lybrand, Tony T. Yuan and Isaac D. Erbele

Bioengineering, 2024, 11, 425
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Human induced pluripotent stem cell-derived inner ear organoids reveal hair cell damage and plasticity after cisplatin and gentamicin exposure

Amy W. A. Lucassen, Winnie M. C. van den Boogaard, Esther Fousert, Jingyuan Zhang, Karl R. Koehler, John C. M. J. de Groot, Peter Paul G. van Benthem, Wouter H. van der Valk and Heiko Locher

Disease Models & Mechanisms, 2026, 19
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Emerging trends in biosensor and microfluidics integration for inner ear theragnostics

Behrouz Aghajanloo, Simin Nazarnezhad, Faezeh Arshadi, Ajay Giri Prakash Kottapalli, Christopher Pastras and Mohsen Asadnia

Biosensors and Bioelectronics, 2025, 286, 117588
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Artificial hearing systems based on functional cochlea models

Jinke Chang, Sita Tarini Clark, Iwan Roberts, Filip Hrncirik, Zhipeng Zhang and Manohar Bance

Int. J. Extrem. Manuf., 2025, 7, 012003
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Possibilities of Inner Ear Barrier Models for Otologic Drug Development

Yeji Ahn, Seonmin Choi, Minju Kim, Zachary Estlack, Daniel Brown, Jaehong Key, Young Joon Seo and Jungkyu Kim

Advanced Therapeutics, 2025, 8
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Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

Franziska Buck, Jeroen Bugter, Gizem Yorukoglu, Mina Kazemzadeh Dastjerd and Thomas E. Winkler

Advanced Biology, 2026, 10
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How Effective are Exosomes in Overcoming Blood-Labyrinth Barrier in Sensorineural Hearing Loss? A Comprehensive Review of the Literature

Jiawei Du, Shiyi Pan, Shiyu Qiu, Nan Cheng, Lian Chen, Ying Hu, Yongjie Wei, Yuhua Zhang, Jianming Yang, Wei Cao and Qiaojun Fang

IJN, 2026, Volume 21, 1
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Mfsd2a regulates the blood-labyrinth-barrier formation and function through tight junctions and transcytosis

Xiaoju Xu, Ke Xu, Fengqiu Chen, Dehong Yu and Xueling Wang

Hearing Research, 2024, 450, 109048
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The Blood-Labyrinth Barrier: Non-Invasive Delivery Strategies for Inner Ear Drug Delivery

Zhangyi Yi, Xiaoying Wang, Ge Yin and Yu Sun

Pharmaceutics, 2025, 17, 482
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