Novel PPAR-γ agonists as potential neuroprotective agents against Alzheimer's disease: rational design, synthesis, in silico evaluation, PPAR-γ binding assay and transactivation and expression studies

Priya D., Umme Hani, Nazima Haider, Sirajunisa Talath, Dhivya Shanmugarajan, Prabitha P., Archana P. and B. R. Prashantha Kumar

RSC Adv., 2024, 14, 33247
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From clove oil to bioactive agents: synthetic routes, antimicrobial and antiparasitic activities of eugenol derivatives

Rúbia Castro Fernandes Melo Reis, Augusto Vieira Pontes Silva, Adriana da Veiga Torres, Rayssa de Cassia Alves Iemini, Igor Rodrigues Lapa, Lucas Lopardi Franco, Saulo Fehelberg Pinto Braga, Diogo Teixeira Carvalho, Danielle Ferreira Dias and Thiago Belarmino de Souza

Future Medicinal Chemistry, 2024, 16, 2169
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Novel Derivatives of Eugenol as a New Class of PPARγ Agonists in Treating Inflammation: Design, Synthesis, SAR Analysis and In Vitro Anti-Inflammatory Activity

Noor Fathima Anjum, Dhivya Shanmugarajan, B. R. Prashantha Kumar, Syed Faizan, Priya Durai, Ruby Mariam Raju, Saleem Javid and Madhusudan N. Purohit

Molecules, 2023, 28, 3899
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Eugenol Exerted Significant Anti-Oxidant and Anti-Inflammatory Effects on Experimental Colitis via Directly Acting on PPAR-γ

Jun-Jie Huang, Rui-Gang Zhou, Jun Chen, Wei-Long Peng, Cheng-Long Yu, Ming-Jiang Liu, Ruo-Nan Bo, Shao-Jie Yin and Jin-Gui Li

Am. J. Chin. Med., 2025, 53, 1933
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Eugenol Possesses Colitis Protective Effects: Impacts on the TLR4/MyD88/NF-κB Pathway, Intestinal Epithelial Barrier, and Macrophage Polarization

Jun-Jie Huang, Yue-Min Feng, Shu-Mei Zheng, Cheng-Long Yu, Rui-Gang Zhou, Ming-Jiang Liu, Ruo-Nan Bo, Jie Yu and Jin-Gui Li

Am. J. Chin. Med., 2024, 52, 493
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Possible Combinatorial Utilization of Phytochemicals and Extracellular Vesicles for Wound Healing and Regeneration

Sachiko Koyama, Erin L. Weber and Thomas Heinbockel

IJMS, 2024, 25, 10353
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Molecular Insights on Coffee Components as Chemical Antioxidants

Luis Felipe Hernández-Ayala, Eduardo Gabriel Guzmán-López, Adriana Pérez-González, Miguel Reina and Annia Galano

J. Mex. Chem. Soc., 2024, 68, 888
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MAPLE Processed Nanostructures for Antimicrobial Coatings

Ariana Hudiță, Valentina Grumezescu, Oana Gherasim, Alexandru Mihai Grumezescu, Gabriela Dorcioman, Irina Negut, Ovidiu-Cristian Oprea, Bogdan Ștefan Vasile, Bianca Gălățeanu, Carmen Curuțiu and Alina Maria Holban

IJMS, 2022, 23, 15355
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Novel dihydropyrimidines as promising EGFR & HER2 inhibitors: Insights from experimental and computational studies

Syed Faizan, Adil Farooq Wali, Sirajunisa Talath, Muneeb U. Rehman, Yuvaraj Sivamani, Kiran C. Nilugal, Narendra Babu Shivangere, Sabry M. Attia, Ahmed Nadeem, Sumitha Elayaperumal and B.R. Prashantha Kumar

European Journal of Medicinal Chemistry, 2024, 275, 116607
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Antibacterial Agent-Loaded, Novel In Situ Forming Implants Made with Poly(Isosorbide Sebacate) and Dimethyl Isosorbide as a Solvent for Periodontitis Treatment

Monika Śmiga-Matuszowicz, Bożena Nowak and Danuta Wojcieszyńska

Molecules, 2025, 30, 4717
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New 1,2,4-triazole based eugenol derivatives as antiCOX-2 and anticancer agents

Mohammad Mahboob Alam

J.Umm Al-Qura Univ. Appll. Sci., 2024, 10, 555
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Eugenol's electrochemical behavior, complexation interaction with copper chloride, antioxidant activity, and potential drug molecular docking application for Covid-19

Saleh M. Elgushe, Adel Z. El-Sonbati, Mostafa A. Diab, Esam A. Gomaa and Elsayed M. AbouElleef

Colloids and Surfaces B: Biointerfaces, 2024, 244, 114194
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An Update on the Therapeutic Anticancer Potential of Ocimum sanctum L.: “Elixir of Life”

Mohammad Raghibul Hasan, Bader Saud Alotaibi, Ziyad Mohammed Althafar, Ahmed Hussain Mujamammi and Jafar Jameela

Molecules, 2023, 28, 1193
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Development and evaluation of clove oil nanoemulsion-based topical cream for anti-inflammatory activity in mice

Ahsan Shafiq, Irfan Baboo, Zahid Farooq, Hamid Majeed and Valiollah Palangi

Front. Vet. Sci., 2025, 12
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Spicing Up Meat Preservation: Cinnamomum zeylanicum Essential Oil in Meat-Based Functional Foods—A Five-Year Review

Raluca-Aniela Gheorghe-Irimia, Dana Tăpăloagă, Paul-Rodian Tăpăloagă, Oana-Mărgărita Ghimpețeanu, Laurențiu Tudor and Manuella Militaru

Foods, 2024, 13, 2479
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Discovery of a new eugenol-benznidazole hybrid active against different evolutive stages of Trypanosoma cruzi

Ígor Matheus de Melo, Tamires Pereira Camargo, Viviana Aparecida da Silva, Elda Gonçalves dos Santos, Ivo Santana Caldas, Carime Lessa Mansur Pontes, Patricia Hermes Stoco, Miguel de Menezes Vaidergorn, Maria Cristina Nonato and Thiago Belarmino de Souza

Bioorganic Chemistry, 2025, 154, 107993
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Computational Approaches for PPARγ Inhibitor Development: Recent Advances and Perspectives

Ayanda M. Magwenyane and Hezekiel M. Kumalo

ChemistryOpen, 2025, 14
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Synthesis, anti-amoebic activity and molecular docking simulation of eugenol derivatives against Acanthamoeba sp.

Khairunisa Mohd Zamli, Fatimah Hashim, Siti Aisyah Razali, Hanis Mohd Yusoff, Habsah Mohamad, Fauziah Abdullah and Asnuzilawati Asari

Saudi Pharmaceutical Journal, 2023, 31, 101703
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