Wearable microfluidic immunosensors for point-of-care detection of bio-analytes: a critical review

Emadoddin Amin Sadrabadi, Foad Soleimani, Neda Naseri, Mohsen Ghiasi Tarzi and Kobra Omidfar

J. Mater. Chem. B, 2025, 13, 8609
DOI: 10.1039/D5TB00682A

Real-time, smartphone-based processing of lateral flow assays for early failure detection and rapid testing workflows

Monika Colombo, Léonard Bezinge, Andres Rocha Tapia, Chih-Jen Shih, Andrew J. de Mello and Daniel A. Richards

Sens. Diagn., 2023, 2, 100
DOI: 10.1039/D2SD00197G

The application of nanoparticles in point-of-care testing (POCT) immunoassays

Fengping Hou, Shiqi Sun, Sahibzada Waheed Abdullah, Yu Tang, Xiongxiong Li and Huichen Guo

Anal. Methods, 2023, 15, 2154
DOI: 10.1039/D3AY00182B

Hand-held all-in-one (HAO) self-test kit for rapid and on-site detection of SARS-CoV-2 with colorimetric LAMP

Qingyang Wang, Woong Heo, Seoyeon Choi, Woongsik Jang, Chae Seung Lim and Hyo-Il Jung

Lab Chip, 2024, 24, 3265
DOI: 10.1039/D4LC00199K

In Situ Complexation of sgRNA and Cas12a Improves the Performance of a One-Pot RPA–CRISPR-Cas12 Assay

Jake M. Lesinski, Thomas Moragues, Prerit Mathur, Yang Shen, Carolina Paganini, Léonard Bezinge, Bo Verberckmoes, Bodine Van Eenooghe, Stavros Stavrakis, Andrew J. deMello and Daniel A. Richards

Anal. Chem., 2024, 96, 10443
DOI: 10.1021/acs.analchem.4c01777

Smartphones as Catalysts for Synergistic Nutrition: A New Era in Bioactive Detection, Personalization, and Food System Intelligence

Mohamed Ibrahim Younis, Yahia Ibrahim Sallam, Khaled Fahmy Mahmoud, Zheng Ruan, Rawaa H. Tlay and Tarek Gamal Abedelmaksoud

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.70880

A novel microfluidics PMMA/paper hybrid bioimmunosensor for laser-induced fluorescence detection in the determination of alpha-fetoprotein from serum

Zhaokun Xian, Peng Dai, Wenyun Su, Cuimin Sun, Liming Liu, Hui You and Ying Liu

Microchemical Journal, 2023, 195, 109476
DOI: 10.1016/j.microc.2023.109476

Point-of-care testing of four chronic disease biomarkers in blood based on a low cost and low system complexity microfluidic chip with integrated oxygen-sensitive membrane

Yuan Zhou, Aiping Cui, Dongliu Xiang, Yanan Luan, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang and Kemin Wang

Sensors and Actuators B: Chemical, 2024, 398, 134734
DOI: 10.1016/j.snb.2023.134734

REASSURED diagnostics at point-of-care in sub-Saharan Africa: A scoping review

Boitumelo Moetlhoa, Kuhlula Maluleke, Evans M. Mathebula, Kabelo Kgarosi, Siphesihle R. Nxele, Bonolo Lenonyane, Tivani Mashamba-Thompson and Joao Tiago da Silva Botelho

PLOS Glob Public Health, 2023, 3, e0001443
DOI: 10.1371/journal.pgph.0001443

Comparison of Exosome Isolation Techniques for Clinical Applications

Nadiar M. Mussin, Kulyash R. Zhilisbayeva, Akmaral Baspakova, Reza Shirazi, Seyyed Mojtaba Mousavi, Saltanat Zhumagaliyeva and Amin Tamadon

WKMJ, 2025, 67, 16
DOI: 10.18502/wkmj.v67i1.18271

Rapid Electrochemical Flow Analysis of Urinary Creatinine on Paper: Unleashing the Potential of Two-Electrode Detection

Léonard Bezinge, Niklas Tappauf, Daniel A. Richards, Chih-Jen Shih and Andrew J. deMello

ACS Sens., 2023, 8, 3964
DOI: 10.1021/acssensors.3c01640

FRETting about CRISPR-Cas Assays: Dual-Channel Reporting Lowers Detection Limits and Times-to-Result

Jake M. Lesinski, Nathan K. Khosla, Carolina Paganini, Bo Verberckmoes, Heleen Vermandere, Andrew J. deMello and Daniel A. Richards

ACS Sens., 2024, 9, 3616
DOI: 10.1021/acssensors.4c00652

Challenges and Advances of Hydrogel-Based Wearable Electrochemical Biosensors for Real-Time Monitoring of Biofluids: From Lab to Market. A Review

Hossein Chenani, Mohsen Saeidi, MahsaSadat Adel Rastkhiz, Nafiseh Bolghanabadi, Amir Hossein Aghaii, Mina Orouji, Amir Hatamie and Abdolreza Simchi

Anal. Chem., 2024, 96, 8160
DOI: 10.1021/acs.analchem.3c03942

Biomarker-specific biosensors revolutionise breast cancer diagnosis

Mugip Rahaman Abdul Wahab, Thirunavukkarasu Palaniyandi, Sandhiya Viswanathan, Gomathy Baskar, Hemapreethi Surendran, S.G.D. Gangadharan, Abimanyu Sugumaran, Asha Sivaji, Senthilkumar Kaliamoorthy and Saravanan Kumarasamy

Clinica Chimica Acta, 2024, 555, 117792
DOI: 10.1016/j.cca.2024.117792

Rapid detection of SARS-CoV-2 RNA using a one-step fast multiplex RT-PCR coupled to lateral flow immunoassay

Insaf Bel Hadj Ali, Hejer Souguir, Mouna Melliti, Mohamed Vall Taleb Mohamed, Monia Ardhaoui, Kaouther Ayouni, Sondes Haddad-Boubaker, Yusr Saadi Ben Aoun, Henda Triki and Ikram Guizani

BMC Infect Dis, 2024, 24
DOI: 10.1186/s12879-024-10296-1

Boosting the Clinical Translation of Organ-on-a-Chip Technology

David Caballero, Rui L. Reis and Subhas C. Kundu

Bioengineering, 2022, 9, 549
DOI: 10.3390/bioengineering9100549

Functional Fluoropolymer Surfactants for Droplet Generation in Microfluidics

Xinrong Cheng, Yiqing Wang, Bingzhao Xia, Xiao Tan, Xiangke Li, Yutong Zhu, Yutong He, Yu Wang, Yuhao Zhang, Kehan Liu, Ruirui Qiao and Cheng Zhang

ACS Appl. Polym. Mater., 2024, 6, 14401
DOI: 10.1021/acsapm.4c02392

Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection

Cuiyun Zhou, Feng Jiang, Wanping Chen, Sam R. Nugen and Chenxi Huang

Biosensors and Bioelectronics, 2025, 290, 117946
DOI: 10.1016/j.bios.2025.117946

Paper‐Based Laser‐Pyrolyzed Electrofluidics: An Electrochemical Platform for Capillary‐Driven Diagnostic Bioassays

Léonard Bezinge, Jake M. Lesinski, Akkapol Suea‐Ngam, Daniel A. Richards, Andrew J. deMello and Chih‐Jen Shih

Advanced Materials, 2023, 35
DOI: 10.1002/adma.202302893

Immunocapturing rare cells from blood: A simple and robust microsystem approach

Jiří Smejkal, Petr Aubrecht, Alena Semerádtová, Marcel Štofik, Michaela Liegertová and Jan Malý

Biosensors and Bioelectronics, 2023, 227, 115155
DOI: 10.1016/j.bios.2023.115155

Integrative modeling of hemodynamic changes and perfusion impairment in coronary microvascular disease

Monika Colombo, Palak Chaudhry, Yvonne Oberholzer and Andrew J. deMello

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1204178

Tuning Hydrophobicity of Paper Substrates for Effective Colorimetric detection of Glucose and Nucleic acids

Sujesh Sudarsan, Prashil Shetty, Raja Chinnappan and Naresh Kumar Mani

Anal Bioanal Chem, 2023, 415, 6449
DOI: 10.1007/s00216-023-04921-2

Magnetically Actuated Hydrogel Stamping-Assisted Cellular Mechanical Analyzer for Stored Blood Quality Detection

Le Yu, Longfei Chen, Yantong Liu, Jiaomeng Zhu, Fang Wang, Linlu Ma, Kezhen Yi, Hui Xiao, Fuling Zhou, Fubing Wang, Long Bai, Yimin Zhu, Xuan Xiao and Yi Yang

ACS Sens., 2023, 8, 1183
DOI: 10.1021/acssensors.2c02507

Machine learning and statistical classification in CRISPR-Cas12a diagnostic assays

Nathan K. Khosla, Jake M. Lesinski, Marcus Haywood-Alexander, Andrew J. deMello and Daniel A. Richards

Biosensors and Bioelectronics, 2025, 279, 117402
DOI: 10.1016/j.bios.2025.117402