A novel approach combining network pharmacology and experimental validation to study the protective effect of ginsenoside Rb1 against cantharidin‐induced hepatotoxicity in mice

Lijuan Xiong, Kexin Lin, Tianmu He, Xingyan Liu, Rui Yuan, Xiaofei Li and Jianyong Zhang

Basic Clin Pharma Tox, 2024, 134, 737
DOI: 10.1111/bcpt.13999

Downregulation of IGFBP7 Alleviates LPS-induced Inflammation and Apoptosis in WI-38 Cells via Enhancing Mitophagy

Li Qiu and Zhaoming Huang

Cell Biochem Biophys, 2024, 83, 1565
DOI: 10.1007/s12013-024-01567-4

Matrine relieved DHAV-1-induced hepatocyte excessive interferon and pyroptosis by activating mitophagy

Weiran Wang, Xiang Fu, Bolin Gu, Mengxin Hu and Jiaguo Liu

Poultry Science, 2025, 104, 104601
DOI: 10.1016/j.psj.2024.104601

α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic injury

Yanghuan Yu, Jipeng Xu, Hao Li, Jia Lv, Yaqin Zhang, Ruiyan Niu, Jundong Wang, Yangfei Zhao and Zilong Sun

Chemico-Biological Interactions, 2023, 385, 110719
DOI: 10.1016/j.cbi.2023.110719

SQYC formula improves the efficacy of PD-1 monoclonal antibodies in MSS colorectal cancer by regulating dendritic cell mitophagy via the PINK1-Parkin pathway

Hong Wang, Yi Ji, Shan Deng, Xiao ying Qin, Xie tao Ye, Ye yang Sun, Xiao yu Che, Lin Yang, Chu yue Huang, Yan Chen and Yu ping Liu

Phytomedicine, 2025, 138, 156388
DOI: 10.1016/j.phymed.2025.156388

Pien-Tze-Huang ameliorates autoimmune hepatitis by promoting hepatocyte autophagy via inhibiting miR-342-3p/mTOR signal

Miaohua Liu, Bugao Zhou, Shanshan Li, Yang Wang, Linxin Zheng, Yi Xiong, Xin Zeng and Duanyong Liu

Journal of Ethnopharmacology, 2026, 354, 120491
DOI: 10.1016/j.jep.2025.120491

Ginseng in delaying brain aging: Progress and Perspectives

Jingwen Niu, Guoqi Zhu and Junjie Zhang

Phytomedicine, 2025, 140, 156587
DOI: 10.1016/j.phymed.2025.156587

Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat

Yayu Chen, Gen Wei, Xiaojin Feng, Enjun Lei and Lieliang Zhang

Experimental Neurology, 2024, 379, 114842
DOI: 10.1016/j.expneurol.2024.114842

Mitochondrial ROS, a trigger for mitochondrial dysfunction and inflammasome activation and a therapeutic target in liver diseases

Hala Saeed Jaara and Sandra Torres

Explor Dig Dis, 2024, 3, 474
DOI: 10.37349/edd.2024.00062

Po-Ge-Jiu-Xin decoction alleviate sepsis-induced cardiomyopathy via regulating phosphatase and tensin homolog-induced putative kinase 1 /parkin-mediated mitophagy

Zheng Wang, Yu Wang, Chen Dong, Kaihui Miao, Bing Jiang, Dan Zhou, Kang Dong, Yanjun Wang and Zheng Zhang

Journal of Ethnopharmacology, 2025, 337, 118952
DOI: 10.1016/j.jep.2024.118952

Lactoferrin Alleviates LPS-Induced Oxidative Stress and Necroptosis in Liver by Promoting Mitophagy

Shuang Guan, Shujing Lu, Ranran Zhang, Yuanmeng Wang, Xinyu Yao, Xuming Deng and Jing Lu

J. Agric. Food Chem., 2025, 73, 11948
DOI: 10.1021/acs.jafc.4c12425

The potential of ginsenosides from Panax ginseng against the NLRP3 inflammasome

Yanan Liu, Chaoqing Huang, Yujing Feng, Jianmei Zhang, Zhiqiang Niu, Luyao Qi, Ting Shen, Xinyue Gao and Weicheng Hu

Phytochem Rev, 2025
DOI: 10.1007/s11101-025-10126-5

Eight new triterpenoid saponins from the leaves of Astragalus membranaceus (Fisch.) Bunge and their neuroprotective effects

Wen-xiang Xu, Zhen-yun Liu, Qing-yue Bu, Peng Jiang, Yi-qiang Zhang, Yu-meng Luo, Wei Guan, Xiao-chi Ma, Meng-meng Li, Qing-shan Chen, Li-li Zhang, Hai-xue Kuang, Bing-you Yang and Yan Liu

Fitoterapia, 2025, 183, 106559
DOI: 10.1016/j.fitote.2025.106559

Pyroptosis: A pharmacological target of ginseng and its phytochemical components for human inflammatory diseases

Young-Su Yi

Journal of Ginseng Research, 2025
DOI: 10.1016/j.jgr.2025.08.001

PANoptosis in intestinal epithelium: its significance in inflammatory bowel disease and a potential novel therapeutic target for natural products

Chuanxiang Zhao and Shan Lin

Front. Immunol., 2025, 15
DOI: 10.3389/fimmu.2024.1507065