Mari Vellakkaran, Jagadish Das, Sourajit Bera and Debasis Banerjee
Chem. Commun., 2018,54, 12369-12372
DOI:
10.1039/C8CC06370B,
Communication
The first base-metal catalysed coupling of primary alcohols with methyl-N-heteroaromatics is reported. The use of an earth abundant and nonprecious NiBr2/L1 system enables access to a series of C(sp3)-alkylated N-heteroaromatics. Mechanistic studies have established the participation of a hydrogen-borrowing strategy for α-alkylation.
