Issue 37, 2016
From the journal:

Organic & Biomolecular Chemistry

Modular access to vicinally functionalized allylic (thio)morpholinonates and piperidinonates by substrate-controlled annulation of 1,3-azadienes with hexacyclic anhydrides†‡

Hannah Braunstein,a   Spencer Langevin,a   Monique Khim,a   Jonathan Adamson,a   Katie Hovenkotter,a   Lindsey Kotlarz,a   Brandon Manskera  and  Timothy K. Beng*a  

* Corresponding authors

a Department of Chemistry, Central Washington University, Ellensburg, WA 98926, USA
E-mail: TimothyB@cwu.edu

Abstract

A modular substrate-controlled hexannulation of inherently promiscuous 1,3-azadienes with hexacyclic anhydrides, which affords versatile vicinally functionalized allylic lactams, in high yields, regio- and stereoselectivities is described.

Graphical abstract: Modular access to vicinally functionalized allylic (thio)morpholinonates and piperidinonates by substrate-controlled annulation of 1,3-azadienes with hexacyclic anhydrides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6OB01526C
Article type
Paper
Submitted
18 lug 2016
Accepted
30 ago 2016
First published
05 set 2016

Org. Biomol. Chem., 2016,14, 8864-8872

Permissions

Request permissions

Modular access to vicinally functionalized allylic (thio)morpholinonates and piperidinonates by substrate-controlled annulation of 1,3-azadienes with hexacyclic anhydrides

H. Braunstein, S. Langevin, M. Khim, J. Adamson, K. Hovenkotter, L. Kotlarz, B. Mansker and T. K. Beng, Org. Biomol. Chem., 2016, 14, 8864 DOI: 10.1039/C6OB01526C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements