Vesicular self-assembly of a natural triterpenoid arjunolic acid in aqueous medium: study of entrapment properties and in situ generation of gel–gold nanoparticle hybrid material

Abstract

A natural pentacyclic triterpenoid arjunolic acid self-assembled hierarchically in aqueous solvents yielding vesicular structures of nano to micrometer diameters affording gels. This self-assembly has been utilized for the entrapment and controlled release of anticancer drugs such as doxorubicin at physiological pH. A gel–gold nanoparticle hybrid material has also been prepared by in situ generated gold nanoparticles at room temperature.