Nitric oxide release from S-nitrosoglutathione (GSNO)

Abstract

In the presence of Cu²⁺ (10^–5 M) very little NO is generated from GSNO at ≡10^–3 M at pH 7.4, whereas the reaction is quantitative at ≡10^–6 M; this is explicable in terms of the complexation of Cu²⁺ by the product GSSG.

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