Catalytic asymmetric reaction of lithium ester enolates with imines

Abstract

An external chiral tridentate amino diether ligand 7 catalyzed the condensation reaction of a lithium ester enolate 2 with an imine 3 to give the enantiomerically enriched β-lactam 4 in high yield.

References

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7. The absolute configuration and ee were determined according to the reported procedure (ref. 5).
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