Themed collection RSC Advances Biological & Medicinal Chemistry year in review 2024


Advancements in enzyme immobilization on magnetic nanomaterials: toward sustainable industrial applications
Enzymes are widely used in biofuels, food, and pharmaceuticals.
RSC Adv., 2024,14, 17946-17988
https://doi.org/10.1039/D4RA02939A

Combining de novo molecular design with semiempirical protein–ligand binding free energy calculation
Semi-empirical quantum chemistry methods estimate the binding free energies of de novo generated ligand–protein complexes.
RSC Adv., 2024,14, 37035-37044
https://doi.org/10.1039/D4RA05422A

Sugar mimics and their probable binding sites: design and synthesis of thiazole linked coumarin-piperazine hybrids as galectin-1 inhibitors
Synthesis of Gal-1 inhibitors with binding site analysis using 1.2 μs MD replicas and machine learning.
RSC Adv., 2024,14, 36794-36803
https://doi.org/10.1039/D4RA06715K

Reaction contest: hydrolysis versus intramolecular cyclisation reaction in alkyl squaramate esters
The hydrolytic behavior and stability of squaramate esters have been investigated, shedding light on the competition between hydrolysis and intramolecular cyclization reactions, which is crucial for advancing bioconjugate chemistry applications.
RSC Adv., 2024,14, 32126-32132
https://doi.org/10.1039/D4RA04362F

Discovery of new triterpene glycosides from Dendrobium officinale with their α-glucosidase and α-amylase inhibitory activity
Seven new oleanane saponins were discovered from Dendrobium officinale. These saponins containing 29-noroleana-12,20(30)-dien-28-oic acid framework, caffeoyl, and coumaroyl moieties potentially inhibited α-glucosidase and α-amylase activities.
RSC Adv., 2024,14, 12147-12157
https://doi.org/10.1039/D4RA01483A
About this collection
Welcome to RSC Advances Biological & Medicinal Chemistry year in review for 2024!
The articles in this collection have been selected as they have gained great attention within their first year of being published.
We hope you enjoy reading these articles and congratulations to all the authors whose articles are featured!