An Ru-catalyzed carbamoyl-directed C–H functionalization of indoles and indolines with 7-azabenzonorbornadienes results in 2-aminodihydronaphthyl indoles and 7-aminodihydronaphthyl indolines, respectively.
To study the impact of electron-donating and electron-withdrawing substituents on the indoline and [2H]-chromene rings of spiropyrans, we synthesized four spiropyrans with varied substituents, analysed their photoswitching kinetics, and evaluated their antibacterial properties.
A general and authoritative literature overview on Pd-catalyzed cross-dehydrogenative coupling reactions of (hetero)arenes from the origins to 2023, where not only the synthetic aspects were described but also the most relevant mechanistic features.
The first synthetic protocol for the synthesis of cis-2-(2-nitrophenyl)indoline-3-acetic acid derivatives was developed via base-catalyzed cyclization of N-(2-nitrobenzyl)-2-aminocinnamic acid derivatives.
The aldo-keto reductase isoenzymes AKR1C1–3 regulate local steroid hormone availability through the interconversion of active and inactive ligands, thereby modulating prereceptor signaling.