The total syntheses of six ursane triterpenoids have been realized from ursolic acid via a simple monoselective C–H oxygenation approach.
In this work, we comprehensively emphasized the types, structures and the cytotoxicity of triterpenoids from the plant medicines, then proposing structural modification strategies according to their structure-activity relationships for the development anticancer drugs.
Madecassic acid is found to have activity against cytochrome proteins found only in bacteria, offering a new route to antibiotics.
Natural products of pentacyclic triterpenoids: from their discovery and biosynthetic pathways to their heterologous biosynthesis in plant chassis and microbial cell factories.
Pheromones are generally produced by insects in submicrogram amounts which makes it difficult to elucidate their chemical structures. Synthetic approaches are therefore necessary for the unambiguous identification of these natural products.