Carboxypeptidase reactions of the CatA enzyme at different pH values were modelled. The catalytic mechanism is suggested to be hampered by the histidine proton–substrate carboxylate interaction at high pH.
Metallaphotoredox catalysis was used to prepare N-Fmoc-protected homotyrosine and allowed the total on-resin synthesis of the cyclic peptide anabaenopeptin F.
A simple, rapid and efficient multicomponent synthesis of spiroacridines and spiroquinolines was carried out under the influence of acetic acid and their antioxidant properties, DFT, docking and in silico ADMET and drug-likeness properties were explored.
Enzymatic proteomic profiles were examined to comprehend the predominant enzymes involved in the flavor development of salted shrimp paste influenced by Bacillus subtilis K-C3 inoculation (Inoc), compared to those without inoculation (CON).
Phosphonodiamidate prodrugs of the monophosphonate derivatives of HMBPP, a natural phosphoantigen, exhibit potent activation of Vγ9Vδ2 T cells resulting in the lysis of bladder cancer cells in vitro.