Herein, a Lewis base catalyzed trifluoromethylsulfinylation of alkyl alcohols and phenols with N-(trifluoromethylsulfinyl)phthalimide, which is a bench stable electrophilic trifluoromethylsulfinylating reagent, is presented.
A method was developed for direct transfer of the trifluoromethylsulfinyl group to a wide range of nucleophiles by a general reagent N-trifluoromethylsulfinylphthalimide, via the activation of a catalytic or stoichiometric Lewis acid or Lewis base.
A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for the aerobic oxidative esterification of aromatic aldehydes and alcohols has been developed, and the corresponding aromatic esters were provided in moderate to good yields.
The photocatalytic aerobic oxidation of benzyl alcohols provided aromatic aldehydes, and the photocatalytic aerobic oxidation of benzyl alcohols in another aliphatic alcohols afforded aromatic esters.
Herein, we have developed an organophotocatalytic trifluoromethylation of 6-azauracils using inexpensive Langlois reagent to prepare a variety of trifluoromethylated azauracil derivatives under ambient air condition.