Anuradha Singampalli, Pardeep Kumar, Rani Bandela, Sri Mounika Bellapukonda, Srinivas Nanduri and Venkata Madhavi Yaddanapudi
RSC Med. Chem., 2025,16, 5196-5221
Abstract
Indazoles as privileged scaffolds; synthetic strategies; clinical trial compounds; biological activities: anti-tubercular, antifungal, antibacterial, antileishmanial, anti-Parkinson's, anti-inflammatory, antidiabetic, and anticancer.
Jia Jia, Shuai Chen, Ting Mao, Jinlan Li, Weipiao Li, An-Jun Wang, Dezhi Yang, Zhengli Liu, Chun-Yang He and Zhang Feng
Org. Chem. Front., 2023,10, 5389-5394
Abstract
Herein, we report a t-BuONa-promoted method for the site-selective silylation of 2H-indazoles.
Thibault Gallavardin and Xavier Franck
Org. Biomol. Chem., 2026, Advance Article
Abstract
The indazole scaffold, with its planar, π-conjugated structure, enables extensive derivatization and tunable luminescence. This makes it ideal for sensing, bioimaging, and materials science, including applications like cell staining and drug development.
Jimmy Wang, Aaron Mccreanney, Amelia Taylor-Young, Harriet A. M. Fenton, Rayyan Miah, Rebecca A. Johnson, James Clarke, Adam Hopkins, Ricky Jones, William Waddington, Steven J. Fussell, Matthew Badland, Benjamin Pibworth and Robert Walton
RSC Adv., 2024,14, 6367-6373
From themed collection:
RSC Advances Organic Chemistry year in review 2024
Abstract
A scalable and selective N1-alkylation of indazoles broad in scope and suitable for manufacturing scale.
Shengneng Ying, Xingru Liu, Tao Guo, Xuan Li, Min Zhou, Xia Wang, Mengxue Zhu, Hongmei Jiang and Qing-Wen Gui
RSC Adv., 2023,13, 581-585
Abstract
Bromoaryl compounds have attracted great attention in organic chemistry, especially for the synthesis of pharmaceutical intermediates.