Polydiacetylene (PDA) supramolecules exhibit a conformation-dependent colorimetric response to external triggers.
Polydiacetylene/copolymer paper sensors were developed to detect five breath volatile organic compounds indicative of early lung cancer, including ethylbenzene, 2-butanone, hexanal, 2-ethylhexanol, and undecane.
Our study presents a PDA-based liposome sensor detecting Salmonella rapidly and accurately via colorimetric response. Functionalized with a Salmonella-binding aptamer, this sensor achieves detection within 15 minutes, visible to the naked eye.
The intestinal microbiota undergoes diurnal compositional and functional oscillations within a day, which affect the metabolic homeostasis of the host and exacerbate the occurrence of obesity.
Aptasensors for thrombin, which feature a sandwich-type configuration, hold great promise in terms of their potential applications in diagnostics and therapeutics.