A TFA-catalyzed dearomative cyanidation of isoquinoline under solvent-free conditions is described, which features broad substrate compatibility, 100 mmol scale synthesis ability and operational simplicity.
This work reports a protocol for the direct α-cyanation/N-acylation of 1,2,3,4-tetrahydroisoquinolines via a one-pot photoredox and Reissert-type reaction using air as the oxidant and acyl cyanide as acyl and cyano source at ambient temperature.
This review surveys traditional and modern methods for synthesizing indoles from nitroarenes, including one-pot, tandem, cycloaddition, photochemical, and electrochemical strategies for efficient access to functionalized indoles.
This feature article outlines the up-to-date implementation of anion-binding catalysis for the enantioselective dearomatization of hereoarenes, expanding the chemical space by converting available flat building blocks into valuable chiral molecules.
Supported Ir(III) photocatalyst covalently linked to glass balls surface by a brush polymer has been synthesized. The new hybrid photocatalyst has been applied in Cross dehydrogenative coupling and recycled 10 time without loss of activity.