CuI-catalyzed dehalogenative ring-opening trifluoromethylations of geminal dihalocyclopropanes delivered stereodefined trisubstituted ethylenes bearing X and a CH2CF3 group on the same carbon.
Stretching or striking a hydrogel results in its acidification by up to 2 pH units. The mechanically robust hydrogel offers promise as a synthetic platform for mechanically adaptive aqueous systems.
Cloke–Wilson rearrangement is utilized to process cyclopropyl constituting functional groups and results in stable five-membered heterocycles. This rearrangement is also involved in the total synthesis of various natural products.
In this tutorial, reaction scopes, limitations and mechanisms of radical acylations are summarized and discussed according to reaction types and catalytic systems.
Mechanical activation of reactions can reduce significantly the amounts of solvent and energy required to form covalent organic bonds.