This paper presents a metal-free synthetic protocol for assembling novel benzofuro[2,3-c]pyridin-3-ols (BFPYOLs) using 2,3-disubstituted benzofuran derivatives and their photoluminescence properties.
An innovative and efficient synthetic route featuring DDQ-promoted cascade oxidation, cyanation/cyclization to produce 2-benzoylbenzofurans and benzofuro[2,3-c]pyridines from 2′-hydroxyethyl cinnamate and phenacyl bromides has been developed.
Our attempts to access these heteroatom-containing aromatic hexacycles are reported, as well as their photophysical properties, and ability to inhibit the activity of PIM 1 and 2 protein kinases.
This paper describes the design and fabrication of a Ni/Arg@zeolite-Y nanocomposite, and investigates its application as a multifunctional nanocatalyst in the one-pot synthesis of thieno[2,3-d]pyrimidinone derivatives.
The design, synthesis, and anticancer evaluation via topoisomerase inhibition of 2-(4-bromobenzyl) tethered 4-amino aryl/alkyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines are reported.