Ascophyllum nodosum polysaccharide regulates gut microbiota metabolites to protect against colonic inflammation in mice

Lilong Wang, Chunhong Yan, Linlin Wang, Chunqing Ai, Songtao Wang, Caihong Shen, Yuqin Tong and Shuang Song

Food Funct., 2023, 14, 810
DOI: 10.1039/D2FO02964B

A comparative study of the hypolipidemic effects and mechanisms of action ofLaminaria japonica- andAscophyllum nodosum-derived fucoidans in apolipoprotein E-deficient mice

Tian Liu, Xue Wang, Yan-Ming Wang, Feng-Rong Sui, Xue-Ying Zhang, Hai-Di Liu, Dong-Yue Ma, Xiao-Xiao Liu and Shou-Dong Guo

Food Funct., 2024, 15, 5955
DOI: 10.1039/D3FO05521C

Supplement of Caulerpa lentillifera polysaccharide by pre‐prandial gavage and free feeding demonstrates differences to prevent obesity and gut microbiota disturbance in mice

Ying You, Haoran Song, Linlin Wang, Zhengqi Liu, Xiaoming Guo, Chunqing Ai, Shuang Song and Beiwei Zhu

J Sci Food Agric, 2023, 103, 3840
DOI: 10.1002/jsfa.12298

Navigating the challenges in fucoidan industrialization: factors affecting biological activity and strategies for application of functional material

Kyung Yuk Ko, Dineth Pramuditha Nagahawatta, Hyo-Geun Lee, Liyanage Nisansala Madushani, Dinusha Shriomala Dissanayake and You-Jin Jeon

Food Sci Biotechnol, 2025
DOI: 10.1007/s10068-025-01937-5

Role of herbal medicine and gut microbiota in the prevention and treatment of obesity

Qiao Zhang, Yaya Bai, Wenxiao Wang, Jiajia Li, Li Zhang, Yuping Tang and Shijun Yue

Journal of Ethnopharmacology, 2023, 305, 116127
DOI: 10.1016/j.jep.2022.116127

Orally administrated fucoidan and its low-molecular-weight derivatives are absorbed differentially to alleviate coagulation and thrombosis

Xiaona Sun, Chunhong Yan, Yinghuan Fu, Chunqing Ai, Jingran Bi, Wei Lin and Shuang Song

International Journal of Biological Macromolecules, 2024, 255, 128092
DOI: 10.1016/j.ijbiomac.2023.128092

Anti-Obesity Effects of Sulphated Polysaccharides Derived from Marine Macro Algae or Seaweeds: A Systematic Review and Meta-Analysis

S’thandiwe Nozibusiso Magwaza, Vunene Nkateko Chabalala, Nothando Philile Hlongwane, Huda Ismail and Md. Shahidul Islam

Marine Drugs, 2024, 22, 528
DOI: 10.3390/md22120528

Fucosylated chondroitin sulfate alleviates diet-induced obesity by modulating intestinal lipid metabolism and colonic microflora

Shan Li, Ronghua Guo, Xiang Gao, Yin Wang, Jiaxin Wen, Ting Zhao, Xiaofei Guo, Junhui Li, Shiguo Chen and Duo Li

International Journal of Biological Macromolecules, 2024, 283, 137371
DOI: 10.1016/j.ijbiomac.2024.137371

Polysaccharide extracted from Atractylodes macrocephala improves the spleen deficiency constipation in mice by regulating the gut microbiota to affect the 5‐HT synthesis

Lei Chen, Xiangbing Chang, Chuntao Wu, Guofu Luo, Peifeng Zhang and Wei Tian

Neurogastroenterology Motil, 2024, 36
DOI: 10.1111/nmo.14875

An overview of fucoidan electrospun nanofibers: Fabrication, modification, characterizations and applications

Najmeh Oliyaei, Ammar B. Altemimi, Elahe Abedi and Seyed Mohammad Bagher Hashemi

Food Chemistry, 2025, 467, 142318
DOI: 10.1016/j.foodchem.2024.142318

Potential anti‐obesity effects of fucoidan from Malaysian brown seaweed (Sargassum binderi) by in vivo study

Nur Akmal Solehah Din, Ainaatul Asmaa' Ishak, Syahida Maarof, Hafeedza Abdul Rahman, Noor‐Soffalina Sofian‐Seng, Noorul Syuhada Mohd Razali, Seng Joe Lim and Wan Aida Wan Mustapha

Int J of Food Sci Tech, 2024, 59, 3402
DOI: 10.1111/ijfs.17096

Interactions between Gut Microbiota and Natural Bioactive Polysaccharides in Metabolic Diseases: Review

Yu Pi, Miaoyu Fang, Yanpin Li, Long Cai, Ruyi Han, Wenjuan Sun, Xianren Jiang, Liang Chen, Jun Du, Zhigang Zhu and Xilong Li

Nutrients, 2024, 16, 2838
DOI: 10.3390/nu16172838

A Comprehensive Review of the Cardioprotective Effect of Marine Algae Polysaccharide on the Gut Microbiota

Kit-Leong Cheong, Biao Yu, Jing Chen and Saiyi Zhong

Foods, 2022, 11, 3550
DOI: 10.3390/foods11223550

Platycodonis radix polysaccharides suppress progression of high-fat-induced obesity through modulation of intestinal microbiota and metabolites

Nannan Zhi, Xiangwei Chang, Liangping Zha, Kailun Zhang, Jutao Wang and Shuangying Gui

Phytomedicine, 2025, 142, 156653
DOI: 10.1016/j.phymed.2025.156653

A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways

Shan He, Wei-Bing Peng, Hong-Lei Zhou, Xian-Jun Fu, Yan-Hua Sun and Zhen-Guo Wang

Pharmaceuticals, 2023, 16, 462
DOI: 10.3390/ph16030462

Fucoidan attenuates chronic colitis and behavioral deficits by reshaping gut microbiota-brain axis balance

Zi-Wei Ye, Zhong-Yu Yuan, Jun Wang, Hua Li, Cheng-Fu Li, Guang-Hui Xu, Li-Tao Yi and Wei-Feng Huang

Journal of Functional Foods, 2024, 112, 105951
DOI: 10.1016/j.jff.2023.105951

Konjac glucomannan Inhibits Appetite of Obese Mice by Suppressing Hypothalamic Inflammatory Response and Agrp/Npy Neuron Expression

Hong Jin, Lanlan Yao, Wenjing Chen, Tao Hou, Jing Li and Bin Li

J. Agric. Food Chem., 2024, 72, 24489
DOI: 10.1021/acs.jafc.4c05901

Exploring the potential of Fucoidan from Laminaria japonica: A comprehensive review of its biological activities and benefits for human

Hui Wan, Yu-Xin Zhang, Zhi-Cheng Gao, Guan-Yue Shan, Fei Liu and Hai-Jun Li

International Journal of Biological Macromolecules, 2025, 307, 142297
DOI: 10.1016/j.ijbiomac.2025.142297

Effects of chitosan and its oligosaccharide on gut microbiota and metabolites disturbed by excessive protein consumption in vivo and in vitro

Linlin Wang, Lilong Wang, Nan Wang, Chen Song, Chengrong Wen and Shuang Song

Food Bioscience, 2024, 57, 103555
DOI: 10.1016/j.fbio.2023.103555

Fucoidan ameliorates rotenone-induced Parkinsonism in mice by regulating the microbiota-gut-brain axis

Xiaojing Yang, Xuan Zhang, Yufang Ma, Sheng Li, Qingshan Wang, Jau-Shyong Hong, Guangli Yu, Bing Qi, Jie Wang, Chengkang Liu, Qingsen Shang, Xuefei Wu and Jie Zhao

International Journal of Biological Macromolecules, 2024, 283, 137373
DOI: 10.1016/j.ijbiomac.2024.137373

Fucoidan as a promising strategy for anti-obesity in animal models: A systematic review and meta-analysis

Seon Kyeong Park, Yu Geon Lee, Jae-Ho Park and Soo-Hyun Park

Algal Research, 2025, 90, 104199
DOI: 10.1016/j.algal.2025.104199

Polysaccharides targeting autophagy to alleviate metabolic syndrome

Hongxia Li, Zeting Ye, Guangjuan Zheng and Zuqing Su

International Journal of Biological Macromolecules, 2024, 283, 137393
DOI: 10.1016/j.ijbiomac.2024.137393

Evaluation of antioxidant and anti-obesity potential of Sargassum extracts

Ya-Ting Chen, Yu-Wen Huang, Tsai-Ying Shen, Chih-Chung Wu, Jyh-Jye Wang and Shu-Ling Hsieh

J Food Sci Technol, 2023, 60, 1723
DOI: 10.1007/s13197-023-05707-1