In vitro evaluation and in situ intestinal absorption characterisation of paeoniflorin nanoparticles in a rat model

Yifei Xiao, Qidong Wei, Lixin Du, Zhihua Guo and Ya Li

RSC Adv., 2024, 14, 22113
DOI: 10.1039/D4RA03419H

One-step self-assembly of curcumin-loaded zein/sophorolipid nanoparticles: physicochemical stability, redispersibility, solubility and bioaccessibility

Yongkai Yuan, Jiawei Huang, Shuguang He, Mengjie Ma, Dongfeng Wang and Ying Xu

Food Funct., 2021, 12, 5719
DOI: 10.1039/D1FO00942G

A review of curcumin in food preservation: Delivery system and photosensitization

Xiang Lan, Yueyue Liu, Lei Wang, Haiyan Wang, Zhe Hu, Hao Dong, Zhiwen Yu and Yongkai Yuan

Food Chemistry, 2023, 424, 136464
DOI: 10.1016/j.foodchem.2023.136464

Development of pH-driven zein/tea saponin composite nanoparticles for encapsulation and oral delivery of curcumin

Yongkai Yuan, Junzi Xiao, Peiyao Zhang, Mengjie Ma, Dongfeng Wang and Ying Xu

Food Chemistry, 2021, 364, 130401
DOI: 10.1016/j.foodchem.2021.130401

Strategies to Protect and Deliver Curcumin via Zein Nanocomposites for Food Applications

Alkassoumi Hassane Hamadou, Jiyao Zhang and Bin Xu

Food Reviews International, 2024, 40, 2969
DOI: 10.1080/87559129.2024.2315065

Nano-Sized Fucoidan Interpolyelectrolyte Complexes: Recent Advances in Design and Prospects for Biomedical Applications

Natallia V. Dubashynskaya, Ekaterina R. Gasilova and Yury A. Skorik

IJMS, 2023, 24, 2615
DOI: 10.3390/ijms24032615

Novel Nanocrystal Injection of Insoluble Drug Anlotinib and Its Antitumor Effects on Hepatocellular Carcinoma

Mei Luo, Huiwei Sun, Qiyu Jiang, Yantao Chai, Congshu Li, Bin Yang and Zhixian Hong

Front. Oncol., 2021, 11
DOI: 10.3389/fonc.2021.777356

Surface coating of zein nanoparticles to improve the application of bioactive compounds: A review

Yongkai Yuan, Mengjie Ma, Ying Xu and Dongfeng Wang

Trends in Food Science & Technology, 2022, 120, 1
DOI: 10.1016/j.tifs.2021.12.025

Chondroitin Sulphate: An emerging therapeutic multidimensional proteoglycan in colon cancer

Amina T. Mneimneh and Mohammed M. Mehanna

International Journal of Biological Macromolecules, 2024, 254, 127672
DOI: 10.1016/j.ijbiomac.2023.127672

Fabrication and characterization of teriflunomide-loaded chondroitin sulfate hybridized zein nanoparticles for the management of triple negative breast cancer

Naveen Rajana, Lakshmi Tulasi Naraharisetti, Nalla Usha Kumari, Ravindra Vasave, Sri Pada Datta Chigurupati, Anamika Sharma, Chandraiah Godugu and Neelesh Kumar Mehra

International Journal of Biological Macromolecules, 2025, 300, 140316
DOI: 10.1016/j.ijbiomac.2025.140316

Exploring the colloidal stability of curcumin nanoparticles formed by nanoprecipitation

Nicolas Didat, Jordane Jasniewski, Pierrick Durand, Sabine Bouguet-Bonnet, Younes Bouizi and Florentin Michaux

Current Research in Food Science, 2026, 12, 101275
DOI: 10.1016/j.crfs.2025.101275

Chondroitin Sulphate-based hydrogels loaded with folic acid-functionalized nanoparticles to target colorectal cancer

Mudassir Abbasi, Muhammad Sohail, Syed Ahmed Shah, Aya Hamid Mohammad Qalawlus and Syeda Ayesha Farhana

Journal of Drug Delivery Science and Technology, 2025, 114, 107479
DOI: 10.1016/j.jddst.2025.107479

Effect of adjusting pH and chondroitin sulfate on the formation of curcumin-zein nanoparticles: Synthesis, characterization and morphology

Simin Feng, Yuxin Sun, Dan Wang, Peilong Sun and Ping Shao

Carbohydrate Polymers, 2020, 250, 116970
DOI: 10.1016/j.carbpol.2020.116970

Folic acid-decorated alginate nanoparticles loaded hydrogel for the oral delivery of diferourylmethane in colorectal cancer

Mudassir Abbasi, Muhammad Sohail, Muhammad Usman Minhas, Arshad Mahmood, Syed Ahmed Shah, Abubakar Munir and Mehboob-Ur-Rehman Kashif

International Journal of Biological Macromolecules, 2023, 233, 123585
DOI: 10.1016/j.ijbiomac.2023.123585

Toxicity Evaluation and Controlled-Release of Curcumin-Loaded Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles: In Vitro and In Vivo Models

Anna L. Luss, Dmitry V. Bagrov, Anne V. Yagolovich, Ekaterina V. Kukovyakina, Irina I. Khan, Vadim S. Pokrovsky, Maria V. Shestovskaya, Marine E. Gasparian, Dmitry A. Dolgikh and Andrey N. Kuskov

Pharmaceutics, 2023, 16, 8
DOI: 10.3390/pharmaceutics16010008

Preparation and application of curcumin loaded with citric acid crosslinked chitosan-gelatin hydrogels

Jing Yang, Anbang Duan, Liping Shen, Qingye Liu, Fei Wang and Yongping Liu

International Journal of Biological Macromolecules, 2024, 264, 130801
DOI: 10.1016/j.ijbiomac.2024.130801

Marine-derived uronic acid-containing polysaccharides: Structures, sources, production, and nutritional functions

Min Yang, Deqing Zhou, Hang Xiao, Xiaodan Fu, Qing Kong, Changliang Zhu, Zhenlian Han and Haijin Mou

Trends in Food Science & Technology, 2022, 122, 1
DOI: 10.1016/j.tifs.2022.02.013

Fabrication and characterization of self-assembled whey protein isolate/short linear glucan core–shell nanoparticles for sustained release of curcumin

Xiaojing Li, Ting Xu, Caie Wu, Gongjian Fan, Tingting Li, Yaosong Wang and Dandan Zhou

Food Chemistry, 2023, 407, 135124
DOI: 10.1016/j.foodchem.2022.135124

Enhancing the stability and biological activity of curcumin through incorporating zein-sodium alginate-egg white peptides hybrid assemblies

Hui Zhang, Xiaoxia Shi, Yajuan Li, Shanglin Li, Leiyi Zhang, Xinyi Huang, Meng Yang, Zhiyang Du, Jingbo Liu and Ting Zhang

Food Bioscience, 2024, 59, 103868
DOI: 10.1016/j.fbio.2024.103868

Quercetin-Loaded Zein/Carboxymethyl Chitosan Nanoparticles: Preparation, Characterization and Evaluation for Enhanced Stability and Antioxidant Activity

Haiqi Yu, Wanjun Chen, Yuhong Su, Mengdie Mo, Fei Yu and Xiaodong Chen

Molecules, 2026, 31, 288
DOI: 10.3390/molecules31020288

Effect of different drying methods on zein‐based microcapsules loaded with Artemisia argyis essence obtained by anti‐solvent precipitation

Qunna Xu, Zhongxue Bai, Jianzhong Ma, Mengchen Huang and Jiaojiao Li

J of Applied Polymer Sci, 2021, 138
DOI: 10.1002/app.50921

Construction of a Ternary Composite Colloidal Structure of Zein/Soy Protein Isolate/Sodium Carboxymethyl Cellulose to Deliver Curcumin and Improve Its Bioavailability

Chong Yu, Jingyu Shan, Hao Ju, Xiao Chen, Guangsen Xu and Yanchao Wu

Foods, 2023, 12, 2692
DOI: 10.3390/foods12142692

Single/co-encapsulation capacity and physicochemical stability of zein and foxtail millet prolamin nanoparticles

Xiao Chen, Yan-Chao Wu, Ying Liu, Liu-Hong Qian, Yu-He Zhang and Hui-Jing Li

Colloids and Surfaces B: Biointerfaces, 2022, 217, 112685
DOI: 10.1016/j.colsurfb.2022.112685

Microbial transglutaminase-induced cross-linking of sodium caseinate as the coating stabilizer of zein nanoparticles

Jiaping Liu, Yaqiong Zhang, Songzhe He, Aimei Zhou, Boyan Gao, Mengyu Yan and Liangli (Lucy) Yu

LWT, 2021, 138, 110624
DOI: 10.1016/j.lwt.2020.110624

Fabrication, characterization, physicochemical stability and simulated gastrointestinal digestion of pterostilbene loaded zein-sodium caseinate-fucoidan nanoparticles using pH-driven method

Qianyuan Liu, Yang Qin, Jingjing Chen, Bo Jiang and Tao Zhang

Food Hydrocolloids, 2021, 119, 106851
DOI: 10.1016/j.foodhyd.2021.106851

Investigation of a novel smart and active packaging materials: Nanoparticle-filled carrageenan-based composite films

Yahong Han, Mingrui Zhou, David Julian McClements, Fuguo Liu, Cheng Cheng, Jinwei Xiong, Ming Zhu and Shuai Chen

Carbohydrate Polymers, 2023, 301, 120331
DOI: 10.1016/j.carbpol.2022.120331

Improvement of physicochemical stability and digestive properties of quercetagetin using zein-chondroitin sulfate particles prepared by antisolvent co-precipitation

Yue Zhuo, Yuehui Liang, Duoxia Xu, David Julian McClements, Suqing Wang, Qi Li, Yahong Han, Fuguo Liu and Shuai Chen

International Journal of Biological Macromolecules, 2023, 242, 125109
DOI: 10.1016/j.ijbiomac.2023.125109

Effects of microencapsulation in dairy matrix on the quality characteristics and bioavailability of docosahexaenoic acid astaxanthin

Qun Gao, Xing Qiao, Lu Yang, Yunrui Cao, Zhaojie Li, Jie Xu and Changhu Xue

J Sci Food Agric, 2022, 102, 5711
DOI: 10.1002/jsfa.11919

In-situ electrophoretic deposition (EPD) and anti-solvent precipitation of tannic acid-loaded zein particles, copper-doped bioactive glass, and sodium carboxymethyl cellulose coatings for orthopedic applications

Zoya Hadzhieva, Can Sinsoysal and Aldo R. Boccaccini

Progress in Organic Coatings, 2026, 210, 109641
DOI: 10.1016/j.porgcoat.2025.109641

pH-driven formation of nano SPI-based ternary complex towards co-delivery of curcumin and Zn at different ratios with synergistic neuroprotective activity

Qi Li, Dan Yuan, Zhicheng Niu, Qibo Zhang, Qiangzhong Zhao, Mouming Zhao and Feibai Zhou

Food Bioscience, 2024, 59, 103957
DOI: 10.1016/j.fbio.2024.103957

Extracellular matrix component-derived nanoparticles for drug delivery and tissue engineering

Katie J. Hogan, Marissa R. Perez and Antonios G. Mikos

Journal of Controlled Release, 2023, 360, 888
DOI: 10.1016/j.jconrel.2023.07.034

Egg white-derived peptides co-assembly-reinforced zein/chondroitin sulfate nanoparticles for orally colon-targeted co-delivery of quercetin in colitis mitigation

Sitong Ma, Jingbo Liu, Yajuan Li, Yingying Liu, Shanglin Li, Yang Liu, Ting Zhang, Meng Yang, Chunmei Liu and Zhiyang Du

Food Bioscience, 2025, 65, 106161
DOI: 10.1016/j.fbio.2025.106161

A review of factors affecting the stability of zein-based nanoparticles loaded with bioactive compounds: from construction to application

Yongkai Yuan, Mengjie Ma, Dongfeng Wang and Ying Xu

Critical Reviews in Food Science and Nutrition, 2023, 63, 7529
DOI: 10.1080/10408398.2022.2047881

Carrageenan-based sustainable biomaterials for intelligent food packaging: A review

Sneha Sabu Mathew, Amit K. Jaiswal and Swarna Jaiswal

Carbohydrate Polymers, 2024, 342, 122267
DOI: 10.1016/j.carbpol.2024.122267

The curcumin-loaded zein-shellac nanoparticles using pH-driven method: Fabrication, characterization, and anti-inflammatory effect

Xinyi Lv, Zijian Wu, Limin Wang, Peibo Guo, Ao Qu, Wenjing Liang, Pengbo Zheng, Yuan Li and Wen Zhang

Journal of Functional Foods, 2025, 125, 106692
DOI: 10.1016/j.jff.2025.106692

Astaxanthin-loaded whey protein/pullulan composite nanodispersions with enhanced stability, bioaccessibility, and antioxidant activity

Zhiyi Ai, Qianxi Zhao, Yankai Liu, Guangquan Ren, Yu Wang, Bo Nan and Yuhua Wang

LWT, 2026, 241, 119042
DOI: 10.1016/j.lwt.2026.119042

Oral Core–Shell Nanoparticles Embedded in Hydrogel Microspheres for the Efficient Site-Specific Delivery of Magnolol and Enhanced Antiulcerative Colitis Therapy

Xiao Wang, Huan Gu, Huan Zhang, Jing Xian, Jingjing Li, Chaomei Fu, Chen Zhang and Jinming Zhang

ACS Appl. Mater. Interfaces, 2021, 13, 33948
DOI: 10.1021/acsami.1c09804

In vitro kinetics characterisation of polymeric nanoparticles for anticancer therapy

Umar Azhan, Izzat Fahimuddin Mohamed Suffian, Siti Fairuz Che Othman and Hazrina Hadi

JoP, 2024, 4, 279
DOI: 10.31436/jop.v4i2.322

pH-driven Zein–peanut protein isolate composite nanoparticles for stabilizing pickering emulsions and enhancing resveratrol delivery

Sufang Chen, Weiwei Cheng, Wenrui Liu, Erna Li, Feng Xiao, Jialiang He, Lili Liu, Suna Han and Baocheng Xu

International Journal of Biological Macromolecules, 2025, 323, 147191
DOI: 10.1016/j.ijbiomac.2025.147191

Construction of biopolymer-based nanoencapsulation of functional food ingredients using the pH-driven method: a review

Yongkai Yuan, Mengjie Ma, Ying Xu and Dongfeng Wang

Critical Reviews in Food Science and Nutrition, 2023, 63, 5724
DOI: 10.1080/10408398.2021.2023858

Effect of fish sperm deoxyribonucleic acid encapsulation on stability, bioaccessibility, redispersibility, and solubilization of curcumin

Yongkai Yuan, Wanying Xu, Mengjie Ma, Shuaizhong Zhang, Dongfeng Wang and Ying Xu

Food Bioscience, 2022, 48, 101746
DOI: 10.1016/j.fbio.2022.101746

Preparation of malic acid cross-linked zein nanoparticles as novel vehicles for enhancing the antioxidant activity of curcumin

Fei Yu, Hongcheng Luo, Haiqi Yu, Mengdie Mo, Chudong He, Hua Yang and Xiao Dong Chen

LWT, 2025, 236, 118658
DOI: 10.1016/j.lwt.2025.118658

Delivery of curcumin by shellac encapsulation: Stability, bioaccessibility, freeze-dried redispersibility, and solubilization

Yongkai Yuan, Shuaizhong Zhang, Mengjie Ma, Ying Xu and Dongfeng Wang

Food Chemistry: X, 2022, 15, 100431
DOI: 10.1016/j.fochx.2022.100431

Construction of quaternary ammonium chitosan-coated protein nanoparticles as novel delivery system for curcumin: Characterization, stability, antioxidant activity and bio-accessibility

Qianyuan Liu, Qian Zhang, Feihong Jia, Ning Jiang, Cheng Wang, Rongxue Sun and Yanhong Ma

Food Chemistry, 2024, 455, 139923
DOI: 10.1016/j.foodchem.2024.139923

Effect of sophorolipid on the curcumin-loaded ternary composite nanoparticles self-assembled from zein and chondroitin sulfate

Yongkai Yuan, Mengjie Ma, Shuaizhong Zhang, Chengzhen Liu, Peng Chen, Hao Li, Dongfeng Wang and Ying Xu

Food Hydrocolloids, 2021, 113, 106493
DOI: 10.1016/j.foodhyd.2020.106493

Mitochondria-targeted astaxanthin prevents oxidative stress in intestinal crypt epithelial cells by regulating redox balance and mitophagy

Xiaoting Yu, Xunyu Song, Yannan Chen, Yueqi Lv and Mingqian Tan

Food Bioscience, 2025, 68, 106537
DOI: 10.1016/j.fbio.2025.106537

Understanding the nanostructures of prolamin-based oral carrier to deliver functional compounds: A review

Xiao Chen, Zi-Xuan Wang, Wei Liu, Yan-Chao Wu and Hui-Jing Li

Trends in Food Science & Technology, 2024, 150, 104571
DOI: 10.1016/j.tifs.2024.104571

Zein nanoparticles for drug delivery: Preparation methods and biological applications

Luís André de Almeida Campos, Azael Francisco Silva Neto, Maria Cecília Souza Noronha, Milena Ferreira de Lima, Isabella Macário Ferro Cavalcanti and Nereide Stela Santos-Magalhães

International Journal of Pharmaceutics, 2023, 635, 122754
DOI: 10.1016/j.ijpharm.2023.122754

pH-driven self-assembly of alcohol-free curcumin-loaded propylene glycol alginate nanoparticles

Yongkai Yuan, Mengjie Ma, Shuaizhong Zhang, Dongfeng Wang and Ying Xu

International Journal of Biological Macromolecules, 2022, 195, 302
DOI: 10.1016/j.ijbiomac.2021.12.025

Curcumin loaded core-shell biopolymers colloid and its incorporation in Indian Basmati rice: An enhanced stability, anti-oxidant activity and sensory attributes of fortified rice

Shruti Pandey, Vindya H.A., Rani Nithya Darshini K., Anil Kumar K. and Pooja J. Rao

Food Chemistry, 2022, 387, 132860
DOI: 10.1016/j.foodchem.2022.132860

Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies

Yu Chang, Qi Wang, Juqing Huang, Xianliang Luo, Yajuan Huang, Yirui Wu, Peng Chen and Yafeng Zheng

Foods, 2023, 12, 3512
DOI: 10.3390/foods12183512

Co-encapsulation of Egg-White-Derived Peptides (EWDP) and Curcumin within the Polysaccharide-Based Amphiphilic Nanoparticles for Promising Oral Bioavailability Enhancement: Role of EWDP

Meng Yang, Jingbo Liu, Yajuan Li, Qi Yang, Chunmei Liu, Xuanting Liu, Biying Zhang, Hui Zhang, Ting Zhang and Zhiyang Du

J. Agric. Food Chem., 2022, 70, 5126
DOI: 10.1021/acs.jafc.1c08186

Recent advances in nutraceutical delivery systems constructed by protein–polysaccharide complexes: A systematic review

Tianqi Cao, Zihao Wei and Changhu Xue

Comp Rev Food Sci Food Safe, 2025, 24
DOI: 10.1111/1541-4337.70115

Encapsulation and delivery of curcumin in cellulose nanocrystals nanoparticles using pH-driven method

Yongkai Yuan, Shuaizhong Zhang, Mengjie Ma, Dongfeng Wang and Ying Xu

LWT, 2022, 155, 112863
DOI: 10.1016/j.lwt.2021.112863

Encapsulation of melatonin in zein/pectin composite nanoparticles: Fabrication, characterization, and in vitro release property

Zhu-Jun Zhang, Wen Sun, Ce Wang, Bin Lai, Jia-Nan Yan and Hai-Tao Wu

Food Chemistry, 2025, 465, 142051
DOI: 10.1016/j.foodchem.2024.142051

Co-Encapsulation of Curcumin and Diosmetin in Nanoparticles Formed by Plant-Food-Protein Interaction Using a pH-Driven Method

Chong Yu, Jingyu Shan, Ze Fu, Hao Ju, Xiao Chen, Guangsen Xu, Yang Liu, Huijing Li and Yanchao Wu

Foods, 2023, 12, 2861
DOI: 10.3390/foods12152861