Does chronic consumption of orange juice improve cardiovascular risk factors in overweight and obese adults? A systematic review and meta-analysis of randomized controlled trials

Lu Li, Nini Jin, Kexin Ji, Yueyue He, He Li and Xinqi Liu

Food Funct., 2022, 13, 11945
DOI: 10.1039/D2FO02195A

Plant bioactive compounds from Mediterranean diet improve risk factors for metabolic syndrome

Renalison Farias-Pereira, Joshua B. Zuk and Hannah Khavaran

International Journal of Food Sciences and Nutrition, 2023, 74, 403
DOI: 10.1080/09637486.2023.2232949

Therapeutic Effects of Morinda citrifolia Linn. (Noni) Aqueous Fruit Extract on the Glucose and Lipid Metabolism in High-Fat/High-Fructose-Fed Swiss Mice

Aline Carla Inada, Gabriela Torres Silva, Laleska Pâmela Rodrigues da Silva, Flávio Macedo Alves, Wander Fernando de Oliveira Filiú, Marcel Arakaki Asato, Wilson Hino Kato Junior, Joaquim Corsino, Patrícia de Oliveira Figueiredo, Fernanda Rodrigues Garcez, Walmir Silva Garcez, Renée de Nazaré Oliveira da Silva, Rosangela Aparecida dos Santos-Eichler, Rita de Cássia Avellaneda Guimarães, Karine de Cássia Freitas and Priscila Aiko Hiane

Nutrients, 2020, 12, 3439
DOI: 10.3390/nu12113439

Nutritional science: Diet, lifestyle and health

I. A. Macdonald

Nutrition Bulletin, 2019, 44, 292
DOI: 10.1111/nbu.12391

Orange juice intake and lipid profile: a systematic review and meta-analysis of randomised controlled trials

Mohammad Reza Amini, Fatemeh Sheikhhossein, Elham Bazshahi, Hamed Rahimi, Hamid Ghalandari, Ehsan Ghaedi and Moein Askarpour

J Nutr Sci, 2023, 12
DOI: 10.1017/jns.2023.22

High orange juice consumption with or in-between three meals a day differently affects energy balance in healthy subjects

Franziska A Hägele, Franziska Büsing, Alessa Nas, Julian Aschoff, Lena Gnädinger, Ralf Schweiggert, Reinhold Carle and Anja Bosy-Westphal

Nutr & Diabetes, 2018, 8
DOI: 10.1038/s41387-018-0031-3

Pera orange juice (Citrus sinensis L. Osbeck) alters lipid metabolism and attenuates oxidative stress in the heart and liver of rats treated with doxorubicin

Ronny Peterson Cabral, Ana Paula Dantas Ribeiro, Marina Gaiato Monte, Anderson Seiji Soares Fujimori, Carolina Rodrigues Tonon, Natalia Fernanda Ferreira, Silmeia Garcia Zanatti, Marcos Ferreira Minicucci, Leonardo Antonio Mamede Zornoff, Sergio Alberto Rupp de Paiva and Bertha Furlan Polegato

Heliyon, 2024, 10, e36834
DOI: 10.1016/j.heliyon.2024.e36834

Pera orange (Citrus sinensis) and Moro orange (Citrus sinensis (L.) Osbeck) juices attenuate left ventricular dysfunction and oxidative stress and improve myocardial energy metabolism in acute doxorubicin-induced cardiotoxicity in rats

Ana Paula Dantas Ribeiro, Amanda Gomes Pereira, Márcia Cristina Todo, Anderson Seiji Soares Fujimori, Priscila Portugal dos Santos, Danielle Dantas, Ana Angélica Fernandes, Silmeia Garcia Zanati, Neuza Mariko Aymoto Hassimotto, Leonardo Antônio Mamede Zornoff, Paula Schmidt Azevedo, Marcos Ferreira Minicucci, Sergio A.R. Paiva and Bertha Furlan Polegato

Nutrition, 2021, 91-92, 111350
DOI: 10.1016/j.nut.2021.111350

Orange juice associated with a balanced diet mitigated risk factors of metabolic syndrome: A randomized controlled trial

Olivia Ponce, Renata Benassi and Thais Cesar

Journal of Nutrition & Intermediary Metabolism, 2019, 17, 100101
DOI: 10.1016/j.jnim.2019.100101

Consumption of orange fermented beverage improves antioxidant status and reduces peroxidation lipid and inflammatory markers in healthy humans

Blanca Escudero‐López, Ángeles Ortega, Isabel Cerrillo, María‐Rosario Rodríguez‐Griñolo, Rocío Muñoz‐Hernández, Hada C Macher, Franz Martín, Dámaso Hornero‐Méndez, Pedro Mena, Daniele Del Rio and María‐Soledad Fernández‐Pachón

J Sci Food Agric, 2018, 98, 2777
DOI: 10.1002/jsfa.8774

Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories

K. L. Stanhope, M. I. Goran, A. Bosy‐Westphal, J. C. King, L. A. Schmidt, J.‐M. Schwarz, E. Stice, A. C. Sylvetsky, P. J. Turnbaugh, G. A. Bray, C. D. Gardner, P. J. Havel, V. Malik, A. E. Mason, E. Ravussin, M. Rosenbaum, J. A. Welsh, C. Allister‐Price, D. M. Sigala, M. R. C. Greenwood, A. Astrup and R. M. Krauss

Obesity Reviews, 2018, 19, 1205
DOI: 10.1111/obr.12699

Polyphenol-Rich Beverage Consumption Affecting Parameters of the Lipid Metabolism in Healthy Subjects

Celina Rahn, Tamara Bakuradze, Simone Stegmüller, Jens Galan, Sonja Niesen, Peter Winterhalter and Elke Richling

IJMS, 2023, 24, 841
DOI: 10.3390/ijms24010841

Citrus flavonoids and adhesion molecules: Potential role in the management of atherosclerosis

Farnaz Ebrahimi, Mohammad Mahdi Ghazimoradi, Ghizal Fatima and Roodabeh Bahramsoltani

Heliyon, 2023, 9, e21849
DOI: 10.1016/j.heliyon.2023.e21849

Development of Citrus-Based Functional Jelly and an Investigation of Its Anti-Obesity and Antioxidant Properties

Mingfang Peng, Zhipeng Gao, Yanfang Liao, Jiajing Guo and Yang Shan

Antioxidants, 2022, 11, 2418
DOI: 10.3390/antiox11122418

Acute glycaemic response of orange juice consumption with breakfast in individuals with type 2 diabetes: a randomized cross-over trial

Kenneth Verboven, Lisa Van Ryckeghem, Ralf Schweiggert, Christof B. Steingass, Tin Gojevic, Carrie H. S. Ruxton and Dominique Hansen

Nutr. Diabetes, 2025, 15
DOI: 10.1038/s41387-025-00385-8

Orange juice intake by obese and insulin-resistant subjects lowers specific plasma triglycerides: A randomized clinical trial

Karina Gama dos Santos, Marcos Yukio Yoshinaga, Isaias Glezer, Adriano de Britto Chaves-Filho, Aline Alves de Santana, Cristiane Kovacs, Carlos Daniel Magnoni, Franco Maria Lajolo, Sayuri Miyamoto and Neuza Mariko Aymoto Hassimotto

Clinical Nutrition ESPEN, 2022, 51, 336
DOI: 10.1016/j.clnesp.2022.08.005

An overview of the nutritional quality and health benefits linked to the world diversity of citrus fruits/juices

Claudie Dhuique‐Mayer and Adrient Servent

Journal of Food Science, 2025, 90
DOI: 10.1111/1750-3841.17576

Roles of citrus fruits on energy expenditure, body weight management, and metabolic biomarkers: a comprehensive review

Merve Nur Aslan, Betül Sukan-Karaçağıl and Nilüfer Acar-Tek

Nutrition Reviews, 2024, 82, 1292
DOI: 10.1093/nutrit/nuad116

Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability

Anna Mas-Capdevila, Joan Teichenne, Cristina Domenech-Coca, Antoni Caimari, Josep M Del Bas, Xavier Escoté and Anna Crescenti

Nutrients, 2020, 12, 1488
DOI: 10.3390/nu12051488

Effect of daily intake of a low-alcohol orange beverage on cardiovascular risk factors in hypercholesterolemic humans

I. Cerrillo, B. Escudero-López, A. Ortega, F. Martín and M.S. Fernández-Pachón

Food Research International, 2019, 116, 168
DOI: 10.1016/j.foodres.2018.08.008

100% Fruit Juice Intake, Glucose Profile, and Uric Acid: A Systematic Review

Lanfranco D’Elia, Aquilino Flavio Zarrella, Ilaria Libera Pizzulo, Alessia Attanasio, Domenico Rendina and John L. Sievenpiper

Journal of Medicinal Food, 2025, 28, 743
DOI: 10.1089/jmf.2024.0139

Nutraceuticals: Focus on Anti-Inflammatory, Anti-Cancer, Antioxidant Properties in Gastrointestinal Tract

Giusy Caponio, Tamara Lippolis, Valeria Tutino, Isabella Gigante, Valentina De Nunzio, Rosa Milella, Marica Gasparro and Maria Notarnicola

Antioxidants, 2022, 11, 1274
DOI: 10.3390/antiox11071274

Phytochemicals and Health Benefits of Sweet Orange Fruit and Juice: A Comparative Summary and Reflection on Last Decade of Research

Kewen Wang, Fuqing Gao, Fukai Li, Fengxia Liu, Nan Zhang, Xinglian Zhang, Lei Xu, Xiaojun Liao and Zhenzhen Xu

Food Reviews International, 2025, 1
DOI: 10.1080/87559129.2025.2486285

Health effects of 100% fruit and vegetable juices: evidence from human subject intervention studies

Irene Rossi, Cristiana Mignogna, Daniele Del Rio and Pedro Mena

Nutr. Res. Rev., 2024, 37, 194
DOI: 10.1017/S095442242300015X

Dietary citrus and/or its extracts intake contributed to weight control: Evidence from a systematic review and meta‐analysis of 13 randomized clinical trials

Xinjing Wang, Deming Li, Fang Liu, Yuan Cui and Xinli Li

Phytotherapy Research, 2020, 34, 2006
DOI: 10.1002/ptr.6673

Effects of orange juice intake on cardiovascular risk factors: A systematic review and meta‐analysis of randomized controlled clinical trials

Maryam Motallaei, Nahid Ramezani‐Jolfaie, Mohammad Mohammadi, Shamim Shams‐Rad, Alireza Shahab Jahanlou and Amin Salehi‐Abargouei

Phytotherapy Research, 2021, 35, 5427
DOI: 10.1002/ptr.7173

The effects of hesperidin supplementation or orange juice consumption on anthropometric measures in adults: A meta-analysis of randomized controlled clinical trials

Farhang Djafari, Mahshid Shahavandi, Mohammad Reza Amini, Fatemeh Sheikhhossein, Hossein Shahinfar, Nastaran Payandeh, Alireza Jafari, Kurosh Djafarian, Cain C.T. Clark and Sakineh Shab-bidar

Clinical Nutrition ESPEN, 2021, 43, 148
DOI: 10.1016/j.clnesp.2021.03.036

Improvement of Antioxidant Properties in Fruit from Two Blood and Blond Orange Cultivars by Postharvest Storage at Low Temperature

Lourdes Carmona, Maria Sulli, Gianfranco Diretto, Berta Alquézar, Mónica Alves and Leandro Peña

Antioxidants, 2022, 11, 547
DOI: 10.3390/antiox11030547

Effect of Daily Consumption of Orange Juice on the Levels of Blood Glucose, Lipids, and Gut Microbiota Metabolites: Controlled Clinical Trials

Ana Carolina Delgado Lima, Clara Cecatti, Melaine Priscila Fidélix, Maria Angela Tallarico Adorno, Isabel Kimiko Sakamoto, Thais Borges Cesar and Katia Sivieri

Journal of Medicinal Food, 2019, 22, 202
DOI: 10.1089/jmf.2018.0080

Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice

Emmanuelle Berger, Pascal Colosetti, Audrey Jalabert, Emmanuelle Meugnier, Oscar P.B. Wiklander, Juliette Jouhet, Elisabeth Errazurig-Cerda, Stéphanie Chanon, Dhanu Gupta, Gilles J.P. Rautureau, Alain Geloen, Samir El-Andaloussi, Baptiste Panthu, Jennifer Rieusset and Sophie Rome

Molecular Therapy - Methods & Clinical Development, 2020, 18, 880
DOI: 10.1016/j.omtm.2020.08.009

A Pilot Study Comparing the Effects of Consuming 100% Orange Juice or Sucrose-Sweetened Beverage on Risk Factors for Cardiometabolic Disease in Women

Candice Allister Price, Valentina Medici, Marinelle V. Nunez, Vivien Lee, Desiree M. Sigala, Yanet Benyam, Nancy L. Keim, Ashley E. Mason, Shin-Yu Chen, Mariana Parenti, Carolyn Slupsky, Elissa S. Epel, Peter J. Havel and Kimber L. Stanhope

Nutrients, 2021, 13, 760
DOI: 10.3390/nu13030760

100% Fruit juice intake and cardiovascular risk: a systematic review and meta-analysis of prospective and randomised controlled studies

Lanfranco D’Elia, Monica Dinu, Francesco Sofi, Massimo Volpe, Pasquale Strazzullo, Alessandra Bordoni, Pasquale Strazzullo, Giulia Cairella, Maria Cristina Casiraghi, Lanfranco D’Elia, Valeria del Balzo, Monica Dinu, Daniela Erba, Francesca Garbagnati, Andrea Ghiselli, Nicoletta Pellegrini, Alessandro Pinto, Laura Rossi, Gian Luigi Russo, Francesca Scazzina, Umberto Scognamiglio, Francesco Sofi, Salvatore Vaccaro and Elvira Verduci

Eur J Nutr, 2021, 60, 2449
DOI: 10.1007/s00394-020-02426-7

100 % Fruit juice and measures of glucose control and insulin sensitivity: a systematic review and meta-analysis of randomised controlled trials

Mary M. Murphy, Erin C. Barrett, Kara A. Bresnahan and Leila M. Barraj

J Nutr Sci, 2017, 6
DOI: 10.1017/jns.2017.63

Impact of hesperidin in 100% orange juice on chronic disease biomarkers: A narrative systematic review and gap analysis

Farah J. Tadros and Jeanette Mary Andrade

Critical Reviews in Food Science and Nutrition, 2022, 62, 8335
DOI: 10.1080/10408398.2021.1927976

Association between consumption of fruit or processed fruit and chronic diseases and their risk factors: a systematic review of meta-analyses

Anthony Fardet, Céline Richonnet and André Mazur

Nutrition Reviews, 2019, 77, 376
DOI: 10.1093/nutrit/nuz004

Beneficial effects of citrus flavanones naringin and naringenin and their food sources on lipid metabolism: An update on bioavailability, pharmacokinetics, and mechanisms

Yang Yang, Myah Trevethan, Shu Wang and Ling Zhao

The Journal of Nutritional Biochemistry, 2022, 104, 108967
DOI: 10.1016/j.jnutbio.2022.108967

Spin in Randomised Clinical Trial Reports of Interventions for Obesity

Sle Lee, Jiyoon Won, Seoyeon Kim, Su Jeong Park and Hyangsook Lee

Korean J Acupunct, 2017, 34, 251
DOI: 10.14406/acu.2017.029

The effect of hesperidin supplementation on inflammatory markers in human adults: A systematic review and meta-analysis of randomized controlled clinical trials

Elnaz Lorzadeh, Nahid Ramezani-Jolfaie, Mohammad Mohammadi, Yadollah Khoshbakht and Amin Salehi-Abargouei

Chemico-Biological Interactions, 2019, 307, 8
DOI: 10.1016/j.cbi.2019.04.016

A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism

Kentaro Matsuzaki, Akira Nakajima, Yuanqiang Guo and Yasushi Ohizumi

Nutrients, 2022, 14, 1847
DOI: 10.3390/nu14091847

Effect of berries/apple mixed juice consumption on the positive modulation of human lipid profile

Marta Habanova, Jorge A. Saraiva, Maria Holovicova, Silvia A. Moreira, Liliana G. Fidalgo, Miroslav Haban, Jan Gazo, Marianna Schwarzova, Peter Chlebo and Monika Bronkowska

Journal of Functional Foods, 2019, 60, 103417
DOI: 10.1016/j.jff.2019.103417

Impact of orange juice consumption on cardiovascular disease risk factors: a systematic review and meta-analysis of randomized-controlled trials

Habeeb Alhabeeb, Mohammad Hassan Sohouli, Abolfazl Lari, Somaye Fatahi, Farzad Shidfar, Osama Alomar, Hany Salem, Ismail A. Al-Badawi and Ahmed Abu-Zaid

Critical Reviews in Food Science and Nutrition, 2022, 62, 3389
DOI: 10.1080/10408398.2020.1865263

Orange juice allied to a reduced-calorie diet results in weight loss and ameliorates obesity-related biomarkers: A randomized controlled trial

Carolina Ribeiro, Grace Dourado and Thais Cesar

Nutrition, 2017, 38, 13
DOI: 10.1016/j.nut.2016.12.020

Hesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure: A systematic review and meta‐analysis of randomized controlled clinical trials

Mohammad Mohammadi, Nahid Ramezani‐Jolfaie, Elnaz Lorzadeh, Yadollah Khoshbakht and Amin Salehi‐Abargouei

Phytotherapy Research, 2019, 33, 534
DOI: 10.1002/ptr.6264

An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease

Priscila Silva Figueiredo, Aline Inada, Melina Ribeiro Fernandes, Daniela Granja Arakaki, Karine Freitas, Rita Avellaneda Guimarães, Valter Aragão do Nascimento and Priscila Aiko Hiane

Molecules, 2018, 23, 877
DOI: 10.3390/molecules23040877

Are Fruit Juices Healthier Than Sugar-Sweetened Beverages? A Review

Alexandra Pepin, Kimber L. Stanhope and Pascal Imbeault

Nutrients, 2019, 11, 1006
DOI: 10.3390/nu11051006

Metataxonomics and Metabolomics Profiles in Metabolic Dysfunction-Associated Fatty Liver Disease Patients on a “Navelina” Orange-Enriched Diet

Francesco Maria Calabrese, Emanuela Aloisio Caruso, Valentina De Nunzio, Giuseppe Celano, Giuliano Pinto, Miriam Cofano, Stefano Sallustio, Ilaria Iacobellis, Carmen Aurora Apa, Monica Santamaria, Maria Calasso, Gianluigi Giannelli, Maria De Angelis and Maria Notarnicola

Nutrients, 2024, 16, 3543
DOI: 10.3390/nu16203543

Effect of citrus fruit and juice consumption on risk of developing type 2 diabetes: Evidence on polyphenols from epidemiological and intervention studies

Rizliya Visvanathan and Gary Williamson

Trends in Food Science & Technology, 2021, 115, 133
DOI: 10.1016/j.tifs.2021.06.038