Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger

Valentina Palmieri, Enrique A. Dalchiele, Giordano Perini, Alessandro Motta, Marco De Spirito, Robertino Zanoni, Andrea Giacomo Marrani and Massimiliano Papi

Chem. Commun., 2019, 55, 4186
DOI: 10.1039/C9CC00429G

Converting the personalized biomolecular corona of graphene oxide nanoflakes into a high-throughput diagnostic test for early cancer detection

Massimiliano Papi, Valentina Palmieri, Luca Digiacomo, Francesca Giulimondi, Sara Palchetti, Gabriele Ciasca, Giordano Perini, Damiano Caputo, Maria Cristina Cartillone, Chiara Cascone, Roberto Coppola, Anna Laura Capriotti, Aldo Laganà, Daniela Pozzi and Giulio Caracciolo

Nanoscale, 2019, 11, 15339
DOI: 10.1039/C9NR01413F

Covalent functionalization of graphene oxide withd-mannose: evaluating the hemolytic effect and protein corona formation

Marcelo de Sousa, Carlos H. Z. Martins, Lidiane S. Franqui, Leandro C. Fonseca, Fabrício S. Delite, Evandro M. Lanzoni, Diego Stéfani T. Martinez and Oswaldo L. Alves

J. Mater. Chem. B, 2018, 6, 2803
DOI: 10.1039/C7TB02997G

The protein corona reduces the anticancer effect of graphene oxide in HER-2-positive cancer cells

Lishan Cui, Erica Quagliarini, Siyao Xiao, Francesca Giulimondi, Serena Renzi, Luca Digiacomo, Giulio Caracciolo, Junbiao Wang, Augusto Amici, Cristina Marchini and Daniela Pozzi

Nanoscale Adv., 2022, 4, 4009
DOI: 10.1039/D2NA00308B

Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment

Flavio De Maio, Valentina Palmieri, Alessandro Salustri, Giordano Perini, Maurizio Sanguinetti, Marco De Spirito, Giovanni Delogu and Massimiliano Papi

Nanoscale Adv., 2019, 1, 1421
DOI: 10.1039/C8NA00413G

Potential of graphene-based nanomaterials for cardiac tissue engineering

Fatemeh Edrisi, Nafiseh Baheiraei, Mehdi Razavi, Kaveh Roshanbinfar, Rana Imani and Negin Jalilinejad

J. Mater. Chem. B, 2023, 11, 7280
DOI: 10.1039/D3TB00654A

The effect of incubation conditions on the hemolytic properties of unmodified graphene oxide with various concentrations

Yang Wang, Baomei Zhang and Guangxi Zhai

RSC Adv., 2016, 6, 68322
DOI: 10.1039/C6RA13607A

Graphene oxide touches blood: in vivo interactions of bio-coronated 2D materials

V. Palmieri, G. Perini, M. De Spirito and M. Papi

Nanoscale Horiz., 2019, 4, 273
DOI: 10.1039/C8NH00318A

Graphene Oxide Induced Osteogenesis Quantification by In-Situ 2D-Fluorescence Spectroscopy

Valentina Palmieri, Marta Barba, Lorena Di Pietro, Claudio Conti, Marco De Spirito, Wanda Lattanzi and Massimiliano Papi

IJMS, 2018, 19, 3336
DOI: 10.3390/ijms19113336

Interaction of graphene oxide with cell culture medium: Evaluating the fetal bovine serum protein corona formation towards in vitro nanotoxicity assessment and nanobiointeractions

Lidiane S. Franqui, Marcelo A. De Farias, Rodrigo V. Portugal, Carlos A.R. Costa, Romenia R. Domingues, Antonio G. Souza Filho, Vitor R. Coluci, Adriana F.P. Leme and Diego Stéfani T. Martinez

Materials Science and Engineering: C, 2019, 100, 363
DOI: 10.1016/j.msec.2019.02.066

Fabrication and antimicrobial performance of surfaces integrating graphene-based materials

Patrícia C. Henriques, Inês Borges, Artur M. Pinto, Fernão D. Magalhães and Inês C. Gonçalves

Carbon, 2018, 132, 709
DOI: 10.1016/j.carbon.2018.02.027

Sericin grafted multifunctional curcumin loaded fluorinated graphene oxide nanomedicines with charge switching properties for effective cancer cell targeting

Mohammadjavad Jahanshahi, Elaheh Kowsari, Vahid Haddadi-Asl, Mehdi Khoobi, Jong Hyun Lee, Firoz Babu Kadumudi, Sepehr Talebian, Nazila Kamaly and Mehdi Mehrali

International Journal of Pharmaceutics, 2019, 572, 118791
DOI: 10.1016/j.ijpharm.2019.118791

Synthesis, characterisation and biocompatibility of graphene–L-methionine nanomaterial

Abdelsattar O.E. Abdelhalim, Vladimir V. Sharoyko, Anatolii A. Meshcheriakov, Michail D. Luttsev, Artem A. Potanin, Nailia R. Iamalova, Egor E. Zakharov, Sergei V. Ageev, Andrey V. Petrov, Lubov V. Vasina, Irina L. Solovtsova, Alexei V. Nashchekin, Igor V. Murin and Konstantin N. Semenov

Journal of Molecular Liquids, 2020, 314, 113605
DOI: 10.1016/j.molliq.2020.113605

Enhanced Chemotherapy for Glioblastoma Multiforme Mediated by Functionalized Graphene Quantum Dots

Giordano Perini, Valentina Palmieri, Gabriele Ciasca, Marcello D’Ascenzo, Aniello Primiano, Jacopo Gervasoni, Flavio De Maio, Marco De Spirito and Massimiliano Papi

Materials, 2020, 13, 4139
DOI: 10.3390/ma13184139

The future development of bacteria fighting medical devices: the role of graphene oxide

Valentina Palmieri, Massimiliano Papi, Claudio Conti, Gabriele Ciasca, Giuseppe Maulucci and Marco De Spirito

Expert Review of Medical Devices, 2016, 13, 1013
DOI: 10.1080/17434440.2016.1245612

Curcumin-loaded graphene oxide flakes as an effective antibacterial system against methicillin-resistantStaphylococcus aureus

F. Bugli, M. Cacaci, V. Palmieri, R. Di Santo, R. Torelli, G. Ciasca, M. Di Vito, A. Vitali, C. Conti, M. Sanguinetti, M. De Spirito and M. Papi

Interface Focus., 2018, 8, 20170059
DOI: 10.1098/rsfs.2017.0059

PE_PGRS3 ofMycobacterium tuberculosisis specifically expressed at low phosphate concentration, and its arginine-rich C-terminal domain mediates adhesion and persistence in host tissues when expressed inMycobacterium smegmatis

Flavio De Maio, Basem Battah, Valentina Palmieri, Linda Petrone, Francesco Corrente, Alessandro Salustri, Ivana Palucci, Silvia Bellesi, Massimiliano Papi, Salvatore Rubino, Michela Sali, Delia Goletti, Maurizio Sanguinetti, Riccardo Manganelli, Marco De Spirito and Giovanni Delogu

Cellular Microbiology, 2018, 20, e12952
DOI: 10.1111/cmi.12952

Recent advances in superhydrophobic surfaces and their relevance to biology and medicine

G Ciasca, M Papi, L Businaro, G Campi, M Ortolani, V Palmieri, A Cedola, A De Ninno, A Gerardino, G Maulucci and M De Spirito

Bioinspir. Biomim., 2016, 11, 011001
DOI: 10.1088/1748-3190/11/1/011001

Cytoskeleton-modulating nanomaterials and their therapeutic potentials

Jinwon Park, Yina Wu, Jung Suk Kim, Junho Byun, Jaiwoo Lee and Yu-Kyoung Oh

Advanced Drug Delivery Reviews, 2024, 211, 115362
DOI: 10.1016/j.addr.2024.115362

3D-printed graphene for bone reconstruction

Valentina Palmieri, Wanda Lattanzi, Giordano Perini, Alberto Augello, Massimiliano Papi and Marco De Spirito

2D Mater., 2020, 7, 022004
DOI: 10.1088/2053-1583/ab6a5d

Nanotechnology in the COVID-19 era: Carbon-based nanomaterials as a promising solution

Massimiliano Papi, Marco De Spirito and Valentina Palmieri

Carbon, 2023, 210, 118058
DOI: 10.1016/j.carbon.2023.118058

Interactions Between Graphene‐Based Materials and Biological Surfaces: A Review of Underlying Molecular Mechanisms

Yanyan Chen, Santosh Pandit, Shadi Rahimi and Ivan Mijakovic

Adv Materials Inter, 2021, 8
DOI: 10.1002/admi.202101132

Characterizing graphene oxide waste stream and assessing its impact on anaerobic co-digestion with municipal sludge

Milad Goodarzi, Mohammad Arjmand and Cigdem Eskicioglu

Journal of Environmental Management, 2024, 369, 122376
DOI: 10.1016/j.jenvman.2024.122376

In vitro biocompatibility study of sub-5 nm silica-coated magnetic iron oxide fluorescent nanoparticles for potential biomedical application

Sabrina Foglia, Mario Ledda, Daniela Fioretti, Giovanna Iucci, Massimiliano Papi, Giovanni Capellini, Maria Grazia Lolli, Settimio Grimaldi, Monica Rinaldi and Antonella Lisi

Sci Rep, 2017, 7
DOI: 10.1038/srep46513

Bacteria Meet Graphene: Modulation of Graphene Oxide Nanosheet Interaction with Human Pathogens for Effective Antimicrobial Therapy

Valentina Palmieri, Francesca Bugli, Maria Carmela Lauriola, Margherita Cacaci, Riccardo Torelli, Gabriele Ciasca, Claudio Conti, Maurizio Sanguinetti, Massimiliano Papi and Marco De Spirito

ACS Biomater. Sci. Eng., 2017, 3, 619
DOI: 10.1021/acsbiomaterials.6b00812

Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity

Chengzhu Liao, Yuchao Li and Sie Chin Tjong

IJMS, 2018, 19, 3564
DOI: 10.3390/ijms19113564

Hemocompatibility of Carbon Nanostructures

Mariangela Fedel

C, 2020, 6, 12
DOI: 10.3390/c6010012

Graphene Oxide Coatings Prevent Candida Albicans Biofilm Formation With a Controlled Release of curcumin-loaded Nanocomposites

Valentina Palmieri, Francesca Bugli, Margherita Cacaci, Giordano Perini, Flavio De Maio, Giovanni Delogu, Riccardo Torelli, Claudio Conti, Maurizio Sanguinetti, Marco De Spirito, Robertino Zanoni and Massimiliano Papi

Nanomedicine (Lond.), 2018, 13, 2867
DOI: 10.2217/nnm-2018-0183

The graphene oxide contradictory effects against human pathogens

Valentina Palmieri, Maria Carmela Lauriola, Gabriele Ciasca, Claudio Conti, Marco De Spirito and Massimiliano Papi

Nanotechnology, 2017, 28, 152001
DOI: 10.1088/1361-6528/aa6150

Oleo-polyurethane-carbon nanocomposites: Effects of in-situ polymerization and sustainable precursor on structure, mechanical, thermal, and antimicrobial surface-activity

Younes Ahmadi, Mithilesh Yadav and Sharif Ahmad

Composites Part B: Engineering, 2019, 164, 683
DOI: 10.1016/j.compositesb.2019.01.078

Interactions of graphene with mammalian cells: Molecular mechanisms and biomedical insights

Bo Zhang, Peng Wei, Zhixiang Zhou and Taotao Wei

Advanced Drug Delivery Reviews, 2016, 105, 145
DOI: 10.1016/j.addr.2016.08.009

Circulating miRNAs in Small Extracellular Vesicles Secreted by a Human Melanoma Xenograft in Mouse Brains

Loredana Guglielmi, Marta Nardella, Carla Musa, Ingrid Cifola, Manuela Porru, Beatrice Cardinali, Ilaria Iannetti, Chiara Di Pietro, Giulia Bolasco, Valentina Palmieri, Laura Vilardo, Nicolò Panini, Fabrizio Bonaventura, Massimiliano Papi, Ferdinando Scavizzi, Marcello Raspa, Carlo Leonetti, Germana Falcone, Armando Felsani and Igea D’Agnano

Cancers, 2020, 12, 1635
DOI: 10.3390/cancers12061635

Graphene-Based Scaffolds for Tissue Engineering and Photothermal Therapy

Valentina Palmieri, Marco De Spirito and Massimiliano Papi

Nanomedicine (Lond.), 2020, 15, 1411
DOI: 10.2217/nnm-2020-0050

Principal component analysis of personalized biomolecular corona data for early disease detection

Massimiliano Papi and Giulio Caracciolo

Nano Today, 2018, 21, 14
DOI: 10.1016/j.nantod.2018.03.001

Graphene Quantum Dots’ Surface Chemistry Modulates the Sensitivity of Glioblastoma Cells to Chemotherapeutics

Giordano Perini, Valentina Palmieri, Gabriele Ciasca, Marcello D’Ascenzo, Jacopo Gervasoni, Aniello Primiano, Monica Rinaldi, Daniela Fioretti, Chiara Prampolini, Federica Tiberio, Wanda Lattanzi, Ornella Parolini, Marco De Spirito and Massimiliano Papi

IJMS, 2020, 21, 6301
DOI: 10.3390/ijms21176301

Changes in cellular mechanical properties during onset or progression of colorectal cancer

Gabriele Ciasca, Massimiliano Papi, Eleonora Minelli, Valentina Palmieri and Marco De Spirito

WJG, 2016, 22, 7203
DOI: 10.3748/wjg.v22.i32.7203

Spiky tubular nanoparticles with low protein corona can realize efficient and non-destructive penetration through endothelial barrier

Yuan Huang, Dong Ye, Xiaojing Liu, Hao Chen, Xinxin Luo, Bo Huang, Nayuan Zhou, Hangxing Wang, Qichao Zou, Senbiao Fang, Suxiao Wang and Limin Wu

Journal of Controlled Release, 2024, 374, 1
DOI: 10.1016/j.jconrel.2024.07.060

Protein immobilization on graphene oxide or reduced graphene oxide surface and their applications: Influence over activity, structural and thermal stability of protein

Karan Chaudhary, Krishan Kumar, Pannuru Venkatesu and Dhanraj T. Masram

Advances in Colloid and Interface Science, 2021, 289, 102367
DOI: 10.1016/j.cis.2021.102367

Efficient Spatial Sampling for AFM-Based Cancer Diagnostics: A Comparison between Neural Networks and Conventional Data Analysis

Gabriele Ciasca, Alberto Mazzini, Tanya E. Sassun, Matteo Nardini, Eleonora Minelli, Massimiliano Papi, Valentina Palmieri and Marco de Spirito

Condensed Matter, 2019, 4, 58
DOI: 10.3390/condmat4020058

Exploitation of nanoparticle-protein interactions for early disease detection

Massimiliano Papi, Valentina Palmieri, Sara Palchetti, Daniela Pozzi, Luca Digiacomo, Elia Guadagno, Marialaura del Basso De Caro, Marina Di Domenico, Serena Ricci, Roberto Pani, Morteza Mahmoudi, Angelina Di Carlo and Giulio Caracciolo

Applied Physics Letters, 2019, 114
DOI: 10.1063/1.5098081

The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity

Elisabetta Falvo, Francesca Malagrinò, Alessandro Arcovito, Francesco Fazi, Gianni Colotti, Elisa Tremante, Patrizio Di Micco, Aldo Braca, Roberta Opri, Alessandro Giuffrè, Giulio Fracasso and Pierpaolo Ceci

Journal of Controlled Release, 2018, 275, 177
DOI: 10.1016/j.jconrel.2018.02.025

A Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment and Health

Thabitha P. Dasari Shareena, Danielle McShan, Asok K. Dasmahapatra and Paul B. Tchounwou

Nano-Micro Lett., 2018, 10
DOI: 10.1007/s40820-018-0206-4

Pre-programming the protein corona: From avoidance to endogenous targeting

Nalla Usha Kumari, Sri Pada Datta Chigurupati, Naveen Rajana, Ravindra Vasave, Sumedh Bahadure and Neelesh Kumar Mehra

Journal of Controlled Release, 2026, 389, 114447
DOI: 10.1016/j.jconrel.2025.114447

Surface Functionalization of Graphene‐Based Materials: Biological Behavior, Toxicology, and Safe‐By‐Design Aspects

Zhiling Guo, Swaroop Chakraborty, Fazel Abdolahpur Monikh, Dimitra‐Danai Varsou, Andrew J Chetwynd, Antreas Afantitis, Iseult Lynch and Peng Zhang

Advanced Biology, 2021, 5
DOI: 10.1002/adbi.202100637

Cellular and subcellular interactions of graphene-based materials with cancerous and non-cancerous cells

Shadi Rahimi, Yanyan Chen, Mohsen Zareian, Santosh Pandit and Ivan Mijakovic

Advanced Drug Delivery Reviews, 2022, 189, 114467
DOI: 10.1016/j.addr.2022.114467

Oxidation state of graphene oxide nanosheets drives their interaction with proteins: A case of bovine serum albumin

Neha S. Ekal, Rahul Patil, Nihar Ranjan, Pratap Bahadur and Sanjay Tiwari

Colloids and Surfaces B: Biointerfaces, 2022, 212, 112367
DOI: 10.1016/j.colsurfb.2022.112367

Carbon‐Based Nanomaterials for Antiviral Applications

Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra and Cesar de la Fuente‐Nunez

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202402023

The Crown and the Scepter: Roles of the Protein Corona in Nanomedicine

Rong Cai and Chunying Chen

Advanced Materials, 2019, 31
DOI: 10.1002/adma.201805740