Lipid-based nanoformulations in onychomycosis therapy: addressing challenges of current therapies and advancing treatment

Shiv Kumar Prajapati, Ankit Jain and Meenakshi Bajpai

RSC Adv., 2025, 15, 7799
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Selective delivery of adapalene to the human hair follicle under finite dose conditions using polymeric micelle nanocarriers

Somnath G. Kandekar, Sergio del Río-Sancho, Maria Lapteva and Yogeshvar N. Kalia

Nanoscale, 2018, 10, 1099
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Formulating SLN and NLC as Innovative Drug Delivery Systems for Non-Invasive Routes of Drug Administration

Bruno Fonseca-Santos, Patrícia Bento Silva, Roberta Balansin Rigon, Mariana Rillo Sato and Marlus Chorilli

CMC, 2020, 27, 3623
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Recent Progress of Lipid Nanoparticles-Based Lipophilic Drug Delivery: Focus on Surface Modifications

Yoseph Seo, Hayeon Lim, Hyunjun Park, Jiyun Yu, Jeongyun An, Hah Young Yoo and Taek Lee

Pharmaceutics, 2023, 15, 772
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Solid Lipid Nanoparticles for Topical Drug Delivery: Mechanisms, Dosage Form Perspectives, and Translational Status

Mengyang Liu, Jingyuan Wen and Manisha Sharma

CPD, 2020, 26, 3203
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Solid lipid nanoparticles dispersed topical hydrogel for Co-delivery of adapalene and minocycline for acne treatment

Rushikesh Pawar and Shilpa Dawre

Journal of Drug Delivery Science and Technology, 2023, 80, 104149
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Emergence of Nanotechnology as a Powerful Cavalry against Triple-Negative Breast Cancer (TNBC)

Aiswarya Chaudhuri, Dulla Naveen Kumar, Deepa Dehari, Sanjay Singh, Pradeep Kumar, Pradeep Kumar Bolla, Dinesh Kumar and Ashish Kumar Agrawal

Pharmaceuticals, 2022, 15, 542
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Triphenylphosphonium functionalized Ficus religiosa L. extract loaded nanoparticles improve the mitochondrial function in oxidative stress induced diabetes

Priyanka Karunanidhi, Nitin Verma, Dulla Naveen Kumar, Ashish Kumar Agrawal and Sanjay Singh

AAPS PharmSciTech, 2021, 22
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Formulation, optimization, and in vitro evaluation of nanostructured lipid carriers for topical delivery of Apremilast

Jyotsana R. Madan, Shweta Khobaragade, Kamal Dua and Rajendra Awasthi

Dermatologic Therapy, 2020, 33
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Recent Advances in Nanomaterials for Dermal and Transdermal Applications

Amani Zoabi, Elka Touitou and Katherine Margulis

Colloids and Interfaces, 2021, 5, 18
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Formulation, Development and Optimization of Nanocarriers for Skin Disorder Luliconazole Gel

Manish Kumar Singh and Dr. Sachin Kumar

IJPSRR, 2022, 66
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New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

Shahinaze A. Fouad, Taher A. Badr, Ahmed Abdelbary, Maha Fadel, Rehab Abdelmonem, Bhaskara R. Jasti and Mohamed El-Nabarawi

AAPS PharmSciTech, 2024, 25
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Ascorbyl palmitate/hyaluronan-modified poloxamer 407 nanoparticles for the topical delivery of fisetin to counteract UVB-induced skin photoaging: A novel anti-aging formulation

Asmaa H. Elwan, Soha M. El-Masry, Doaa A. Habib and Mariam Zewail

International Journal of Pharmaceutics, 2025, 682, 125988
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Co-Delivery of Glycyrrhizin and Paclitaxel via Gelatin-Based Core–Shell Nanoparticles Ameliorates 1,2-Dimethylhydrazine-Induced Precancerous Lesions in Colon

Md. Meraj Ansari, Vivek Yadav, Sayali Dighe, Kaushik Kuche, Kanika, Rehan Khan and Sanyog Jain

ACS Biomater. Sci. Eng., 2025, 11, 942
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Skin delivery of resveratrol encapsulated lipidic formulation for melanoma chemoprevention

Padmini Ravikumar, Mahesh Katariya, Sushil Patil, Pratima Tatke and Raviraj Pillai

Journal of Microencapsulation, 2019, 1
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Contribution of Nanoscience Research in Antioxidants Delivery Used in Nutricosmetic Sector

Irene Dini

Antioxidants, 2022, 11, 563
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Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review

Dima Khater, Hamdi Nsairat, Fadwa Odeh, Mais Saleh, Areej Jaber, Walhan Alshaer, Abeer Al Bawab and Mohammad S. Mubarak

Cosmetics, 2021, 8, 39
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Lipid and polymer blended polyester nanoparticles loaded with adapalene for activation of retinoid signaling in the CNS following intravenous administration

David X. Medina, Eugene P. Chung, Robert Bowser and Rachael W. Sirianni

Journal of Drug Delivery Science and Technology, 2019, 52, 927
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Insightful exploring of advanced nanocarriers for the topical/transdermal treatment of skin diseases

Ghada M. El-Zaafarany and Maha Nasr

Pharmaceutical Development and Technology, 2021, 26, 1136
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In vitro and in vivo evaluation of an ionic sensitive in situ gel containing nanotransfersomes for aripiprazole nasal delivery

Somayeh Taymouri, Shabnam Shahnamnia, Azadeh Mesripour and Jaleh Varshosaz

Pharmaceutical Development and Technology, 2021, 26, 867
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Preclinical safety of solid lipid nanoparticles and nanostructured lipid carriers: Current evidence from in vitro and in vivo evaluation

Slavomira Doktorovová, Andjelka B. Kovačević, Maria L. Garcia and Eliana B. Souto

European Journal of Pharmaceutics and Biopharmaceutics, 2016, 108, 235
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Immunostimulatory effect of tetanus toxoid loaded chitosan nanoparticles following microneedles assisted immunization

Krupa Siddhapura, Harshad Harde and Sanyog Jain

Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12, 213
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Acoustic cavitation assisted hot melt mixing technique for solid lipid nanoparticles formulation, characterization, and controlled delivery of poorly water soluble drugs

Raj Kumar, Ashutosh Singh and Neha Garg

Journal of Drug Delivery Science and Technology, 2019, 54, 101277
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Development and Investigation of Vitamin C-Enriched Adapalene-Loaded Transfersome Gel: a Collegial Approach for the Treatment of Acne Vulgaris

Sandhya Vasanth, Akhilesh Dubey, Ravi G.S., Shaila A. Lewis, Vivek M. Ghate, Sally A. El-Zahaby and Srinivas Hebbar

AAPS PharmSciTech, 2020, 21
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Solid lipid nanoparticles and nanostructured lipid carrier-based nanotherapeutics in treatment of psoriasis: a comparative study

Rhythm Arora, Sameer S. Katiyar, Varun Kushwah and Sanyog Jain

Expert Opinion on Drug Delivery, 2017, 14, 165
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Lipid Nanoparticulate Drug Delivery Systems: Recent Advances in the Treatment of Skin Disorders

Stefan R. Stefanov and Velichka Y. Andonova

Pharmaceuticals, 2021, 14, 1083
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Resolving acne with optimized adapalene microspongeal gel, in vivo and clinical evaluations

Rania M. Yehia, Mahmoud H. Teaima, Maha H. Ragaie, Mohamed M. Elmazar, Dalia A. Attia and Mohamed A. El-Nabarawi

Sci Rep, 2024, 14
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Alkyl polyglucoside-based adapalene-loaded microemulsions for targeted dermal delivery: Structure, stability and comparative biopharmaceutical characterization with a conventional dosage form

Nataša Bubić Pajić, Tanja Ilić, Ines Nikolić, Vladimir Dobričić, Ivana Pantelić and Snežana Savić

Journal of Drug Delivery Science and Technology, 2019, 54, 101245
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Polymeric micelles: A novel drug delivery system for the treatment of breast cancer

Aiswarya Chaudhuri, Korra Ramesh, Dulla Naveen Kumar, Deepa Dehari, Sanjay Singh, Dinesh Kumar and Ashish Kumar Agrawal

Journal of Drug Delivery Science and Technology, 2022, 77, 103886
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Ion Pair Strategy in Solid Lipid Nanoparticles: a Targeted Approach to Improve Epidermal Targeting with Controlled Adapalene Release, Resulting Reduced Skin Irritation

Linna B. O. Rodrigues, Flávia A. Lima, Camila P. B. Alves, Elisângela Martins-Santos, Marta M. G. Aguiar, Cleida A. Oliveira, Rodrigo L. Oréfice, Lucas A. M. Ferreira and Gisele A. C. Goulart

Pharm Res, 2020, 37
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Statistically Optimized Tacrolimus and Thymoquinone Co-Loaded Nanostructured Lipid Carriers Gel for Improved Topical Treatment of Psoriasis

Meraj Alam, Md. Rizwanullah, Showkat R. Mir and Saima Amin

Gels, 2023, 9, 515
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Codelivery of Benzoyl Peroxide & Adapalene Using Modified Liposomal Gel for Improved Acne Therapy

Sanyog Jain, Dnyaneshwar P Kale, Rajan Swami and Sameer S Katiyar

Nanomedicine (Lond.), 2018, 13, 1481
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Ionic liquid-based Ionogel: A novel strategy to improve dermal delivery and in vivo efficacy of etodolac in rheumatoid arthritis management

Shrushti Bhamble, Sayali Dighe, Oly Katari, Vivek Yadav, Md. Meraj Ansari and Sanyog Jain

Journal of Molecular Liquids, 2024, 412, 125841
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Nanotechnology-based formulations toward the improved topical delivery of anti-acne active ingredients

Ana Cláudia Paiva-Santos, Filipa Mascarenhas-Melo, Sara Cabanas Coimbra, Kiran D. Pawar, Diana Peixoto, Raquel Chá-Chá, André RTS Araujo, Célia Cabral, Selmo Pinto and Francisco Veiga

Expert Opinion on Drug Delivery, 2021, 18, 1435
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Development of Curcumin and Turmerone Loaded Solid Lipid Nanoparticle for Topical Delivery: Optimization, Characterization and Skin Irritation Evaluation with 3D Tissue Model

Beyza Aydin, Ali Sagiroglu, Dilek Ozturk Civelek, Mustafa Gokce and Fatemeh Bahadori

IJN, 2024, Volume 19, 1951
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Gemcitabine-Phospholipid Complex Loaded Lipid Nanoparticles for Improving Drug Loading, Stability, and Efficacy against Pancreatic Cancer

Chander Parkash Dora, Varun Kushwah, Vivek Yadav, Kaushik Kuche and Sanyog Jain

Mol. Pharmaceutics, 2024, 21, 2699
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SLN and NLC for topical, dermal, and transdermal drug delivery

Eliana B. Souto, Iara Baldim, Wanderley P. Oliveira, Rekha Rao, Nitesh Yadav, Francisco M. Gama and Sheefali Mahant

Expert Opinion on Drug Delivery, 2020, 17, 357
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The development of a solid lipid nanoparticle (SLN)-based lacticin 3147 hydrogel for the treatment of wound infections

Aoibhín Ryan, Pratikkumar Patel, Poonam Ratrey, Paula M. O’Connor, Julie O’Sullivan, R. Paul Ross, Colin Hill and Sarah P. Hudson

Drug Deliv. and Transl. Res., 2023, 13, 2407
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Development of Adapalene Loaded Liposome Based Gel for Acne

Asma Arooj, Asim Ur Rehman, Muhammad Iqbal, Iffat Naz, Aiyeshah Alhodaib and Naveed Ahmed

Gels, 2023, 9, 135
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Delivery of adapalene using a novel topical gel based on tea tree oil nano-emulsion: Permeation, antibacterial and safety assessments

Roqya Najafi-Taher, Behnaz Ghaemi and Amir Amani

European Journal of Pharmaceutical Sciences, 2018, 120, 142
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Optimized Ribociclib nanostructured lipid carrier for the amelioration of skin cancer: Inferences from ex-vivo skin permeation and dermatokinetic studies

Mohammed F. Aldawsari, Mohammad Azhar Kamal, Mohamed F. Balaha, Talha Jawaid, Mohammed Jafar, Sana Hashmi, Majid Ahmad Ganaie and Aftab Alam

Saudi Pharmaceutical Journal, 2024, 32, 101984
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Lipid-Based Nanoparticles as a Pivotal Delivery Approach in Triple Negative Breast Cancer (TNBC) Therapy

Aiswarya Chaudhuri, Dulla Naveen Kumar, Rasheed A. Shaik, Basma G. Eid, Ashraf B. Abdel-Naim, Shadab Md, Aftab Ahmad and Ashish Kumar Agrawal

IJMS, 2022, 23, 10068
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Development and Evaluation of Particulate Microcarriers of Adapalene as a Topical Delivery System

Divya D. Jain and Namita D. Desai

DDL, 2019, 9, 222
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Triptolide-Loaded Solid Lipid Nanogel: Preparation and In-Vitro Evaluation

Chun-Feng Lu, Ye Dai, Yun Tao, Qiu-Yi Yin, Yan Jiang and Ting-Wang Jiang

j biomed nanotechnol, 2024, 20, 231
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‬‬‬‬‬‬‬‬Development and characterization of polymeric nanoparticle-based formulation of adapalene for topical acne therapy‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬

Tannaz Ramezanli, Zheng Zhang and Bozena B. Michniak-Kohn

Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 13, 143
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A Review on Novel Topical Formulations of Vitamins

Juhi Desai and Rashmi Mallya

Journal of Reports in Pharmaceutical Sciences, 2021, 10, 159
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The emerging role of nanotechnology in skincare

Lucia Salvioni, Lucia Morelli, Evelyn Ochoa, Massimo Labra, Luisa Fiandra, Luca Palugan, Davide Prosperi and Miriam Colombo

Advances in Colloid and Interface Science, 2021, 293, 102437
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Phospholipid Complex-based Topical Gel for Codelivery of Erlotinib and Methotrexate in Psoriasis

Sanyog Jain, Shivani Mali, Junia Akhtar, Chander Parkash Dora and Rahul R. Mahajan

AAPS PharmSciTech, 2025, 26
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