Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li, -Mg and -Zn reagents

Vasudevan Dhayalan, Vishal S. Dodke, Marappan Pradeep Kumar, Hatice Seher Korkmaz, Anja Hoffmann-Röder, Pitchamuthu Amaladass, Rambabu Dandela, Ragupathy Dhanusuraman and Paul Knochel

Chem. Soc. Rev., 2024, 53, 11045
DOI: 10.1039/D4CS00369A

Discovery of a novel benzimidazole conjugated quinazolinone derivative as a promising SARS-CoV-2 3CL protease inhibitor

Bui Thi Buu Hue, Huynh Nguyet Huong Giang, Cuong Quoc Nguyen, Feng-Pai Chou, Danh La Duc Thanh, Quang De Tran, Vo Trung Hieu, Lam Hoang Phuong Mai, Hong-Cheu Lin and Tung-Kung Wu

RSC Adv., 2024, 14, 33820
DOI: 10.1039/D4RA03267E

Recent advances and perspectives in the synthesis of bioactive coumarins

E. Calcio Gaudino, S. Tagliapietra, K. Martina, G. Palmisano and G. Cravotto

RSC Adv., 2016, 6, 46394
DOI: 10.1039/C6RA07071J

A facile synthesis and evaluation of new biomolecule-based coumarin–thiazoline hybrids as potent anti-tubercular agents with cytotoxicity, DNA cleavage and X-ray studies

Dinesh S. Reddy, Kallappa M. Hosamani, Hirihalli C. Devarajegowda and Mahantesh M. Kurjogi

RSC Adv., 2015, 5, 64566
DOI: 10.1039/C5RA09508E

Synthesis, characterization, and DNA interaction of novel Pt(ii) complexes and their cytotoxicity, apoptosis and molecular docking

Ming-Chang Zhu, Xiao-Ting Cui, Fu-Chen Zhao, Xiao-Yu Ma, Zheng-Bo Han and En-Jun Gao

RSC Adv., 2015, 5, 47798
DOI: 10.1039/C5RA04972E

Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

Manankar Koley, Jianlin Han, Vadim A. Soloshonok, Subhajit Mojumder, Ramin Javahershenas and Ata Makarem

RSC Med. Chem., 2024, 15, 10
DOI: 10.1039/D3MD00511A

Design and Synthesis of Novel C4‐Linked Substituted 2H‐Chromen‐2‐one‐hypoxanthine Hybrids as Potential Antimicrobial Agents: An Approach to Molecular Docking Studies

Soniya D. Naik and Kallappa M. Hosamani

Journal of Heterocyclic Chem, 2019, 56, 579
DOI: 10.1002/jhet.3432

Design, synthesis, molecular docking study and molecular dynamics simulation of new coumarin-pyrimidine hybrid compounds having anticancer and antidiabetic activity

Duong Ngoc Toan, Nguyen Dinh Thanh, Mai Xuan Truong, Dinh Thuy Van and Nguyen Ngoc Thanh

Med Chem Res, 2023, 32, 1143
DOI: 10.1007/s00044-023-03060-8

Exploring the synthesis and characterization of fac-Re(CO)3L complexes using diethylenetriamine derivative functionalized at the central nitrogen

Margaret W. Ndinguri, Carrie A. Black, Anna L. Gosser, Sara Reitz, Cody Sutphin, Frank R. Fronczek and Lindsay E. Cormier

Inorganica Chimica Acta, 2021, 520, 120291
DOI: 10.1016/j.ica.2021.120291

Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity

Dinesh S. Reddy, Manasa Kongot and Amit Kumar

Tuberculosis, 2021, 127, 102050
DOI: 10.1016/j.tube.2020.102050

Synthesis of coumarin-piperazine derivatives as potent anti-microbial and anti-inflammatory agents, and molecular docking studies

Shrinivas Koparde, Kallappa M. Hosamani, Veena Kulkarni and Shrinivas D. Joshi

Chemical Data Collections, 2018, 15-16, 197
DOI: 10.1016/j.cdc.2018.06.001

Cytotoxic effects of coumarin substituted benzimidazolium salts against human prostate and ovarian cancer cells

Mert Olgun Karataş, Suat Tekin, Bülent Alici and Süleyman Sandal

J Chem Sci, 2019, 131
DOI: 10.1007/s12039-019-1647-0

Structure-dependent of 3-fluorooxindole derivatives interacting with ctDNA: Binding effects and molecular docking approaches

Ze-Yue Huang, Zi-Heng Wang, Ya Niu, Guo-Xi Deng, Ai-Min Bai, Xiao-Yun Li and Yan-Jun Hu

Bioorganic Chemistry, 2022, 121, 105698
DOI: 10.1016/j.bioorg.2022.105698

Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases

Mohamed Mokhtar, Khadijah S. Alghamdi, Nesreen S. Ahmed, Dina Bakhotmah and Tamer S. Saleh

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36, 1453
DOI: 10.1080/14756366.2021.1944126

Design and Synthesis of Potent Anticancer Agents Using Coumarin‐Quinazolinone Based Scaffolds: Exploration of ADME Properties and Molecular Docking Studies

Vardhaman Babagond, Kariyappa Katagi, Mahesh Akki, Dinesh S. Reddy, Hamzad Shanavaz, Ashwini Jaggal and Soumyashree D K

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202400435

Meglumine sulfate catalyzed solvent-free one-pot synthesis of coumarins under microwave and thermal conditions

Leila Moradi, Khadijeh Rabiei and Fateme Belali

Synthetic Communications, 2016, 46, 1283
DOI: 10.1080/00397911.2016.1201512

Design, synthesis of benzocoumarin-pyrimidine hybrids as novel class of antitubercular agents, their DNA cleavage and X-ray studies

Dinesh S. Reddy, Kallappa M. Hosamani and Hirihalli C. Devarajegowda

European Journal of Medicinal Chemistry, 2015, 101, 705
DOI: 10.1016/j.ejmech.2015.06.056

Liquid-crystalline coumarin derivatives: contribution to the tailoring of metal-free sensitizers for solar cells

Aloir A. Merlo, Aline Tavares, Sherdil Khan, Marcos J. Leite Santos and Sergio Ribeiro Teixeira

Liquid Crystals, 2018, 45, 310
DOI: 10.1080/02678292.2017.1324644

Microwave: A Green Contrivance for the Synthesis of N-Heterocyclic Compounds

Trimurti L. Lambat, Paavan Kavi Param Gaitry Chopra and Sami H. Mahmood

COC, 2020, 24, 2527
DOI: 10.2174/1385272824999200622114919

Recent green chemistry approaches for pyrimidine derivatives as a potential anti-cancer agent: An overview (2013–2023)

Kumari Kajal, Ruchi Shakya, Mohd Rashid, Vaibhav Nigam, Balak Das Kurmi, Ghanshyam Das Gupta and Preeti Patel

Sustainable Chemistry and Pharmacy, 2024, 37, 101374
DOI: 10.1016/j.scp.2023.101374

Coumarin-containing hybrids and their anticancer activities

Longfei Zhang and Zhi Xu

European Journal of Medicinal Chemistry, 2019, 181, 111587
DOI: 10.1016/j.ejmech.2019.111587

Design and Synthesis of Novel Imidazopyridine-Chalcone Hybrids As Potent Anti-TB Agents with Their Docking and Cytotoxicity Studies

Rajakumar Patil, Dinesh S. Reddy, Vidya G, Hamzad Shanavaz, Sashivinay Kumar Gaddam, Nikhil Kadam and Deepak Kasai

Russ J Gen Chem, 2025, 95, 2537
DOI: 10.1134/S1070363225602352

Coumarin tethered cyclic imides as efficacious glucose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin

Dinesh S. Reddy, Manasa Kongot, Vishal Singh, Neha Maurya, Rajan Patel, Nitin Kumar Singhal, Fernando Avecilla and Amit Kumar

Bioorganic Chemistry, 2019, 92, 103212
DOI: 10.1016/j.bioorg.2019.103212

Recent Advances in the Green Synthesis of Active N-Heterocycles and Their Biological Activities

Suman Majee, Shilpa, Mansi Sarav, Bimal Krishna Banik and Devalina Ray

Pharmaceuticals, 2023, 16, 873
DOI: 10.3390/ph16060873

Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors

Aladdin M. Srour, Nesreen S. Ahmed, Somaia S. Abd El-Karim, Manal M. Anwar and Salwa M. El-Hallouty

Bioorganic & Medicinal Chemistry, 2020, 28, 115657
DOI: 10.1016/j.bmc.2020.115657

Microwave Assisted Reactions of Azaheterocycles Formedicinal Chemistry Applications

Dorina Amariucai-Mantu, Violeta Mangalagiu, Ramona Danac and Ionel I. Mangalagiu

Molecules, 2020, 25, 716
DOI: 10.3390/molecules25030716

Design, synthesis, molecular docking, anti-proliferative and anti-TB studies of 2H-chromen-8-azaspiro[4.5]decane-7,9-dione conjugates

Smita G. Mane, Dinesh S. Reddy, Kariyappa S. Katagi, Amit Kumar, Ravindra S. Munnolli, Nikhil S. Kadam, Mahesh C. Akki, H. Nagarajaiah and Shrinivas D. Joshi

Journal of Molecular Structure, 2021, 1227, 129530
DOI: 10.1016/j.molstruc.2020.129530

Microwave‐assisted diversified synthesis of pyrimidines: An overview

Kapil Kumar

Journal of Heterocyclic Chem, 2022, 59, 205
DOI: 10.1002/jhet.4376

Microwave Induced Green Synthesis: Sustainable Technology for Efficient Development of Bioactive Pyrimidine Scaffolds

Biswa Mohan Sahoo, Bimal Krishna Banik, Bera Venkata Varaha Ravi Kumar, Krishna Chandra Panda, Abhishek Tiwari, Varsha Tiwari, Sunil Singh and Manish Kumar

CMC, 2023, 30, 1029
DOI: 10.2174/0929867329666220622150013

Synthesis, Anticancer Evaluation, and Molecular Docking Studies of Novel (4‐Hydroxy‐2‐Thioxo‐3,4‐Dihydro‐2H‐[1,3]Thiazin‐6‐Yl)‐Chromen‐2‐Ones via a Multicomponent Approach

Archi Sharma, Satish Gudala, Srinivasa Rao Ambati, Santhosh Penta, Yashwanth Bomma, Venkateswara Rao Janapala, Anubhuti Jha and Awanish Kumar

J Chinese Chemical Soc, 2018, 65, 810
DOI: 10.1002/jccs.201700340

Dual functions: A coumarin–chalcone conjugate inhibits cyclic‐di‐GMP and quorum‐sensing signaling to reduce biofilm formation and virulence of pathogens

Yu Zhang, Pramod Bhasme, Dinesh S. Reddy, Dejian Liu, Zhaoxiao Yu, Tianhu Zhao, Yaqian Zheng, Amit Kumar, Haiying Yu and Luyan Z. Ma

mLife, 2023, 2, 283
DOI: 10.1002/mlf2.12087

Synthesis, molecular docking studies and biological evaluation of potent coumarin–carbonodithioate hybrids via microwave irradiation

Sumitra N. Mangasuli, Kallappa M. Hosamani, Praveen Satapute and Shrinivas D. Joshi

Chemical Data Collections, 2018, 15-16, 115
DOI: 10.1016/j.cdc.2018.04.001

Imidazopyridine chalcones as potent anticancer agents: Synthesis, single‐crystal X‐ray, docking, DFT and SAR studies

Dilip Kamble Soumyashree, Dinesh Shrikant Reddy, Honnappa Nagarajaiah, Lohit Naik, Hemantkumar Mohanchand Savanur, Choradi Devendrappa Shilpa, Mayanna Sunitha Kumari, Hamzad Shanavaz and Basavaraj Padmashali

Archiv der Pharmazie, 2023, 356
DOI: 10.1002/ardp.202300106

Design, Synthesis, Biological Evaluation and Computational Study of Novel Imino‐4‐Aryloxymethyl‐2H‐chromen‐2‐one Derivatives as Potent Anti‐Microbial and Antiinflammatory Agents

Soniya D. Naik, Kallappa M. Hosamani, Delicia A. Barretto and Shrinivas D. Joshi

ChemistrySelect, 2018, 3, 507
DOI: 10.1002/slct.201702240

Catalyzed Methods to Synthesize Pyrimidine and Related Heterocyclic Compounds

Marcos Díaz-Fernández, Saturnino Calvo-Losada, J.-Joaquín Quirante, Francisco Sarabia, Manuel Algarra and M.-Soledad Pino-González

Catalysts, 2023, 13, 180
DOI: 10.3390/catal13010180

Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues

Mohsine Driowya, Aziza Saber, Hamid Marzag, Luc Demange, Rachid Benhida and Khalid Bougrin

Molecules, 2016, 21, 492
DOI: 10.3390/molecules21040492

Rational approaches, design strategies, structure activity relationship and mechanistic insights for therapeutic coumarin hybrids

Harbinder Singh, Jatinder Vir Singh, Kavita Bhagat, Harmandeep Kaur Gulati, Mohit Sanduja, Nitish Kumar, Nihar Kinarivala and Sahil Sharma

Bioorganic & Medicinal Chemistry, 2019, 27, 3477
DOI: 10.1016/j.bmc.2019.06.033

An Overview of Imidazole and Its Analogues As Potent Anticancer Agents

Salik Abdullah and Swastika Ganguly

Future Med. Chem., 2023, 15, 1621
DOI: 10.4155/fmc-2023-0020

Microwave synthesis of coumarin-maltol hybrids as potent antitumor and anti-microbial drugs: An approach to molecular docking and DNA cleavage studies

Shrinivas Koparde, Kallappa M. Hosamani, Delicia A. Barretto and Shrinivas D. Joshi

Chemical Data Collections, 2018, 15-16, 41
DOI: 10.1016/j.cdc.2018.03.004

One-pot solvent-free synthesis of 1,3,5-trisubstituted 1H-pyrazoles catalyzed by H3[PW12O40]/SiO2 under microwave irradiation

Dawei Zhang, Lu Ren, Ailing Liu, Wenyu Li, Yuxin Liu and Qiang Gu

Monatsh Chem, 2022, 153, 257
DOI: 10.1007/s00706-022-02902-2

Microwave-assisted synthesis, computational studies and antibacterial/ anti-inflammatory activities of compounds based on coumarin-pyrazole hybrid

Rakesh R. Chavan and Kallappa M. Hosamani

R. Soc. open sci., 2018, 5, 172435
DOI: 10.1098/rsos.172435

Development of New IDO Inhibitors with Coumarin Pyrimidine Scaffolds as the Potential Anti Cancer Agents

Radhika Chelamalla and Ajitha Makula

CBC, 2020, 16, 1172
DOI: 10.2174/1573407216666191216154856

Coumarin Hydrazone Oxime Scaffolds as Potent Anti‐tubercular Agents: Synthesis, X‐ray crystal and Molecular Docking Studies

Mahesh Akki, Dinesh S. Reddy, Kariyappa S. Katagi, Amit Kumar, Hirihalli C. Devarajegowda, Sunitha Kumari M, Vardhaman Babagond and Shrinivas D. Joshi

ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202203260

Synthesis, crystal structure studies and Hirshfeld surface analysis of novel 4-(4-(pyridin-2-ylmethyleneamino)benzyloxy)-5,7-dimethyl-2H-chromen-2-one

Soniya D. Naik, Shivarudrappa H. Pattanashetty, Kallappa M. Hosamani and S. Madan Kumar

Chemical Data Collections, 2018, 17-18, 490
DOI: 10.1016/j.cdc.2018.11.006

Microwave synthesis, biological screening and computational studies of pyrimidine based novel coumarin scaffolds

Soniya D. Naik, K.M. Hosamani and Shyam Kumar Vootla

Chemical Data Collections, 2018, 15-16, 207
DOI: 10.1016/j.cdc.2018.06.002

One‐potandtwo‐potmethods for chalcone derived pyrimidines synthesis and applications

Saba Farooq and Zainab Ngaini

Journal of Heterocyclic Chem, 2021, 58, 1209
DOI: 10.1002/jhet.4226

Anticancer mechanism of coumarin-based derivatives

Anand Kumar Yadav, Ramina Maharjan Shrestha and Paras Nath Yadav

European Journal of Medicinal Chemistry, 2024, 267, 116179
DOI: 10.1016/j.ejmech.2024.116179

Design, synthesis, characterization, and biological evaluation of novel iminocoumarin derivatives: In vitro anticancer activity against NSCLC and ex vivo NLRP3 inflammasome inhibition supported by docking and ADMET studies

Massinissa Baymout, Amal Rabahi, Louisa Bechohra, Sonia Missiroli, Kenza Saida Ouandjeli, Fouzia Touahra, Paolo Pinton and Carlotta Giorgi

Journal of Molecular Structure, 2026, 1364, 145825
DOI: 10.1016/j.molstruc.2026.145825

Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines

Vinuta Kamat, Dinesh S. Reddy and Amit Kumar

Archiv der Pharmazie, 2023, 356
DOI: 10.1002/ardp.202300008

Biscoumarin–pyrimidine conjugates as potent anticancer agents and binding mechanism of hit candidate with human serum albumin

Dinesh S. Reddy, Manasa Kongot, Vishal Singh, Md. Abrar Siddiquee, Rajan Patel, Nitin K. Singhal, Fernando Avecilla and Amit Kumar

Archiv der Pharmazie, 2021, 354
DOI: 10.1002/ardp.202000181