Nitrogen-bridgehead compounds: overview, synthesis, and outlook on applications

Benedikt W. Grau, Praveen Kumar, Aaron Nilsen and Sanjay V. Malhotra

Org. Biomol. Chem., 2025, 23, 1479
DOI: 10.1039/D4OB01589D

Ultrasound promoted facile one pot synthesis of highly substituted pyran derivatives catalyzed by silica-coated magnetic NiFe2O4nanoparticle-supported H14[NaP5W30O110] under mild conditions

Behrooz Maleki, Mehdi Baghayeri, Sedigheh Ayazi Jannat Abadi, Reza Tayebee and Amir Khojastehnezhad

RSC Adv., 2016, 6, 96644
DOI: 10.1039/C6RA20895A

Chickpea leaf exudates: a green Brønsted acid type biosurfactant for bis(indole)methane and bis(pyrazolyl)methane synthesis

Rupesh C. Patil, Shashikant A. Damate, Dnyandev N. Zambare and Suresh S. Patil

New J. Chem., 2021, 45, 9152
DOI: 10.1039/D1NJ00382H

Nano α-Al2O3supported ammonium dihydrogen phosphate (NH4H2PO4/Al2O3): preparation, characterization and its application as a novel and heterogeneous catalyst for the one-pot synthesis of tetrahydrobenzo[b]pyran and pyrano[2,3-c]pyrazole derivatives

Behrooz Maleki and Samaneh Sedigh Ashrafi

RSC Adv., 2014, 4, 42873
DOI: 10.1039/C4RA07813F

Synthesis of symmetrical N,N′-alkylidene bis-amides catalyzed by silica coated magnetic NiFe2O4 nanoparticle supported polyphosphoric acid (NiFe2O4@SiO2-PPA) and its application toward silver nanoparticle synthesis for electrochemical detection of glucose

Behrooz Maleki and Mehdi Baghayeri

RSC Adv., 2015, 5, 79746
DOI: 10.1039/C5RA16481H

Facile synthesis and investigation of 1,8-dioxooctahydroxanthene derivatives as corrosion inhibitors for mild steel in hydrochloric acid solution

Behrooz Maleki, Ali Davoodi, Mojtaba Vakili Azghandi, Mehdi Baghayeri, Elahe Akbarzadeh, Hojat Veisi, Samaneh Sedigh Ashrafi and Massomeh Raei

New J. Chem., 2016, 40, 1278
DOI: 10.1039/C5NJ02707A

Silica coated magnetic NiFe2O4 nanoparticle supported phosphomolybdic acid; synthesis, preparation and its application as a heterogeneous and recyclable catalyst for the one-pot synthesis of tri- and tetra-substituted imidazoles under solvent free conditions

Behrooz Maleki, Hossein Eshghi, Amir Khojastehnezhad, Reza Tayebee, Samaneh Sedigh Ashrafi, Golnoosh Esmailian Kahoo and Farid Moeinpour

RSC Adv., 2015, 5, 64850
DOI: 10.1039/C5RA10534J

Chemoselective hydration of nitriles to amides using hydrated ionic liquid (IL) tetrabutylammonium hydroxide (TBAH) as a green catalyst

Hojat Veisi, Behrooz Maleki, Mona Hamelian and Samaneh Sedigh Ashrafi

RSC Adv., 2015, 5, 6365
DOI: 10.1039/C4RA09864A

NiFe2O4@B,N,F-tridoped CeO2 (NFTDNC): a mesoporous nanocatalyst in the synthesis of pyrazolopyranopyrimidine and 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives and as an adsorbent

Neha Sharma, Bushra Chowhan, Monika Gupta and Mobina Kouser

Dalton Trans., 2022, 51, 13795
DOI: 10.1039/D2DT01216B

Nano polypropylenimine dendrimer (DAB-PPI-G1): as a novel nano basic-polymer catalyst for one-pot synthesis of 2-amino-2-chromene derivatives

Behrooz Maleki and Safoora Sheikh

RSC Adv., 2015, 5, 42997
DOI: 10.1039/C5RA04458H

Ag@TiO2 nanocomposite; synthesis, characterization and its application as a novel and recyclable catalyst for the one-pot synthesis of benzoxazole derivatives in aqueous media

Behrooz Maleki, Mehdi Baghayeri, Seyed Mohammad Vahdat, Abbas Mohammadzadeh and Somaieh Akhoondi

RSC Adv., 2015, 5, 46545
DOI: 10.1039/C5RA06618B

ChemInform Abstract: Lewis Acid Free Synthesis of 3,4‐Dihydro‐1H‐indazolo[1,2‐b]phthalazine‐1,6,11(2H,13H)‐triones Promoted by 1,1,1,3,3,3‐Hexafluoro‐2‐propanol.

Behrooz Maleki, Samaneh Sedigh Ashrafi and Reza Tayebee

ChemInform, 2015, 46
DOI: 10.1002/chin.201510217

Copper (II) Complex Immobilized on Magnetic Nanoparticles Functionalized with Imine/Thio Ligand (Fe 3 O 4 @SiO 2 -Imine/Thio-Cu(II)): A Novel, Efficient and Reusable Nanomagnetic Catalysts for the Synthesis of 2,4,6-Triaryl Pyridines

Indah Raya, Reena Solanki, Firas Rahi Alhachami, Abduladheem Turki Jalil and Yasser Fakri Mustafa

Polycyclic Aromatic Compounds, 2023, 43, 9399
DOI: 10.1080/10406638.2022.2164015

N-acetyl-PABA@Cu(II) supported on Fe3O4 as the new heterogeneous catalytic system to assist the MCR derived synthesis of 2,2-dimethyl-2H-[1,3]dioxino[4,5-b]pyrrol-4(7H)-ones heterocyclic scaffolds

Yamini Patel, Ashok Kumar and Pratibha Sharma

Next Materials, 2024, 3, 100166
DOI: 10.1016/j.nxmate.2024.100166

Green and efficient synthesis of 1H‐indazolo[1,2‐b] phthalazine‐1,6,11(13H)‐triones using ZrO(NO3)2.2H2O as a novel catalyst and theoretical study of synthesized compounds

Shabnam Saberi Biroon, Nahid Shajari and Hooriye Yahyaei

Journal of Heterocyclic Chem, 2020, 57, 2433
DOI: 10.1002/jhet.3959

Efficient synthesis of sulfones and sulfoxides from sulfides by cobalt-based Schiff complex supported on nanocellulose as catalyst and Oxone as the terminal oxidant

Reza Sandaroos, Behrooz Maleki, Sanaz Naderi and Sahar Peiman

Inorganic Chemistry Communications, 2023, 148, 110294
DOI: 10.1016/j.inoche.2022.110294

Synthesis of orthoaminocarbonitrile tetrahydronaphthalenes catalyzed by butyl-3-methylimidazolium hexafluorophosphate ionic liquid base catalyst

Mahsa Khorasani and Hossein Naeimi

Synthetic Communications, 2022, 52, 1917
DOI: 10.1080/00397911.2022.2119579

DABCO‐Saccharin Acetate as a Novel, Recyclable and Metal‐Free Catalyst for Eco‐Friendly Synthesis of Various Pyridazino[1,2‐a]indazole and 1H‐indazolo[1,2‐b]phthalazine Heterocycles Under Solvent‐Free Conditions

Behjat Pouramiri, Elahe Hadadianpour and Azadeh Parhami

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202403187

A selective heterogeneous cellulose supported Schiff base Cu(II) catalyst for Chan–Evans–Lam coupling

P. S. Pharande, P. M. Mhaldar, T. R. Lohar, S. K. Ghotekar, Tarulata N. Chhowala, G. S. Rashinkar and D. M. Pore

Res Chem Intermed, 2023, 49, 4541
DOI: 10.1007/s11164-023-05089-1

One-pot Synthesis of 2-Amino-2-chromene and 2-Amino-3-cyano-4H-pyran Derivatives Promoted by Potassium Fluoride

Behrooz Maleki and Safoora Sheikh

Organic Preparations and Procedures International, 2015, 47, 368
DOI: 10.1080/00304948.2015.1066647

Chemoselective Synthesis of Tetraketones in Water Catalyzed by Nanostructured Diphosphate Na2CaP2O7

Behrooz Maleki, Massomeh Raei, Heshmatollah Alinezhad, Reza Tayebee and Alireza Sedrpoushan

Organic Preparations and Procedures International, 2018, 50, 288
DOI: 10.1080/00304948.2018.1462055

Induced photoacoustic gratings due to Raman scattering in organic components

Ehsan Koushki and Behrooz Maleki

Dyes and Pigments, 2019, 164, 82
DOI: 10.1016/j.dyepig.2019.01.013

Synergistic applications of nanocomposite, ultrasound, and on‐water synthesis for efficient and green synthesis of spirooxindole derivatives via cascade C–N, C–O, and C–S bond formation

Pankaj Teli, Sunita Teli, Nusrat Sahiba, Shivani Soni and Shikha Agarwal

Applied Organom Chemis, 2024, 38
DOI: 10.1002/aoc.7393

Magnetic copper nanoparticle catalyst on β-cyclodextrin-modifed AlFe2O4 for efficient green synthesis 1H-pyrazolo[1,2-b]phthalazine-5,10-diones

Zahra Moghadasi, Jayanti Makasana, Suhas Ballal, Munther Kadheem, Abhayveer Singh, Kattela Chennakesavulu and Pushpa Negi Bhakuni

Results in Chemistry, 2025, 16, 102415
DOI: 10.1016/j.rechem.2025.102415

5-Sulphosalicylic acid: An expeditious organocatalyst for one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones

Shrikrishna Karhale and Vasant Helavi

SN Appl. Sci., 2020, 2
DOI: 10.1007/s42452-020-3056-x

Chemoselective Synthesis of 2,2′-Arylmethylene bis-(3-Hydroxy-2-cyclohexenes) (“Tetraketones”) in Hexafluoro-2-propanol

Behrooz Maleki, Massomeh Raei, Elahe Akbarzadeh, Hassan Ghasemnejad-Bosra, Alireza Sedrpoushan, Samaneh Sedigh Ashrafi and Mohammad Nabi Dehdashti

Organic Preparations and Procedures International, 2016, 48, 62
DOI: 10.1080/00304948.2016.1127102

1,1,1,3,3,3-hexafluoro-2-propanol as a reusable media: Green and catalyst-free synthesis of pyrano[2,3-d]pyrimidine scaffolds

Farzaneh Mohamadpour

J Chem Sci, 2024, 137
DOI: 10.1007/s12039-024-02334-x

Calcined eggshells as a highly efficient catalyst for the synthesis of 2-amino 4H-chromene derivatives

Swati D. Jadhav and Suresh S. Patil

Res Chem Intermed, 2023, 49, 4805
DOI: 10.1007/s11164-023-05109-0

Synthesis of novel azo‐linked 4‐arylidene‐benzodiazepine using cellulose@SP@catechin@Fe3O4 nanocomposite and study of their antioxidant activity

Tamila Shafaati, Mohammad Nikpassand, Masoud Mokhtary and Leila Zare Fekri

Applied Organom Chemis, 2024, 38
DOI: 10.1002/aoc.7470

Heteropolyacid-based ionic liquid [Simp] 3 PW 12 O 40 nanoparticle as a productive catalyst for the one-pot synthesis of 2H-indazolo[2,1- b ]phthalazine-triones under solvent-free conditions

Reza Tayebee, M. Fattahi Abdizadeh, Behrooz Maleki and Elham Shahri

Journal of Molecular Liquids, 2017, 241, 447
DOI: 10.1016/j.molliq.2017.06.033

One-pot Synthesis of 1-Amidoalkyl-2-naphthols Catalyzed by Polyphosphoric Acid Supported on Silica-coated NiFe2O4 Nanoparticles

Behrooz Maleki, Elham Sheikh, Esmail Rezaei Seresht, Hossein Eshghi, Samaneh Sedigh Ashrafi, Amir Khojastehnezhad and Hojat Veisi

Organic Preparations and Procedures International, 2016, 48, 37
DOI: 10.1080/00304948.2016.1127098

One-Pot Synthesis of Bicyclic ortho-Aminocarbonitrile and Multisubstituted Cyclohexa-1,3-dienamine Derivatives

Behrooz Maleki, Roghaie Rooky, Esmail Rezaei-Seresht and Reza Tayebee

Organic Preparations and Procedures International, 2017, 49, 557
DOI: 10.1080/00304948.2017.1384282

Silica-coated magnetic NiFe2O4 nanoparticles-supported H3PW12O40; synthesis, preparation, and application as an efficient, magnetic, green catalyst for one-pot synthesis of tetrahydrobenzo[b]pyran and pyrano[2,3-c]pyrazole derivatives

Behrooz Maleki, Hossein Eshghi, Mohammad Barghamadi, Negar Nasiri, Amir Khojastehnezhad, Samaneh Sedigh Ashrafi and Omid Pourshiani

Res Chem Intermed, 2016, 42, 3071
DOI: 10.1007/s11164-015-2198-8

Caesium carbonate supported on hydroxyapatite‐encapsulated Ni0.5Zn0.5Fe2O4 nanocrystallites as a novel magnetically basic catalyst for the one‐pot synthesis of pyrazolo[1,2‐b]phthalazine‐5,10‐diones

Behrooz Maleki, Samaneh Barat Nam Chalaki, Samaneh Sedigh Ashrafi, Esmail Rezaee Seresht, Farid Moeinpour, Amir Khojastehnezhad and Reza Tayebee

Applied Organom Chemis, 2015, 29, 290
DOI: 10.1002/aoc.3288

Facile Protocol for the Synthesis of 2-Amino-4H-Chromene Derivatives using Choline Chloride/Urea

Behrooz Maleki, Reza Tayebee, Ali Khoshsima and Farshid Ahmadpoor

Organic Preparations and Procedures International, 2021, 53, 34
DOI: 10.1080/00304948.2020.1833623

An Attractive and Efficient Procedure for Synthesis of Heterocyclic Structures: MNPs-Bis(2-Hydroxyethyl)-Guanidine-Ni Nanocomposite as a Novel and Green Nanomagnetic Catalyst for Multicomponent Reactions

Indrajit Patra, Ahmed M. Abdulhadi, Nasier Saadoon, Hawraa A. Kareem and Zuhair I. Al Mashhadani

Polycyclic Aromatic Compounds, 2023, 43, 8186
DOI: 10.1080/10406638.2022.2146146

Synthesis of benzoimidazoquinazolinone and indolylxanthenone derivatives using Keggin-type heteropoly-11-molybdo-1-vanadophosphoric acid supported on Montmorillonite K-10 clay as catalyst: a green approach

Antony Muthu Prasanna, Murugan Kumaresan, Karuppaiah Selvakumar, Meenakshisundaram Swaminathan and Ponnusamy Sami

Res Chem Intermed, 2022, 48, 5029
DOI: 10.1007/s11164-022-04859-7

Experimental and Theoretical Investigation on Imidazole Derivatives Using Magnetic Nanocatalyst: Green Synthesis, Characterization, and Mechanism Study

Niloufar Nasehi, Behrooz Mirza and Somayeh Soleimani-Amiri

Polycyclic Aromatic Compounds, 2023, 43, 7890
DOI: 10.1080/10406638.2022.2141275

Green and eco-friendly synthesis of quinolone substituted indolyl- 4H -chromenes via C–C bond formation

Satish Kumar Burra, Vaikunta Rao Lakinani, Raghunadh Akula and Chiranjeevi Yankkanti

Synthetic Communications, 2024, 54, 207
DOI: 10.1080/00397911.2023.2292696

Zn( L‐proline)2 as a powerful and reusable organometallic catalyst for the very fast synthesis of 2‐amino‐4H‐benzo[g]chromene derivatives under solvent‐free conditions

Behrooz Maleki, Saeed Babaee and Reza Tayebee

Applied Organom Chemis, 2015, 29, 408
DOI: 10.1002/aoc.3306

New basic ionic liquid from ethan-1,2-diyl bis (hydrogen sulfate) and DBU (1,8-diazobicyclo[5.4.0]undec-7-ene) as an efficient catalyst for one-pot synthesis of xanthene derivatives

Behrooz Maleki, Elahe Akbarzadeh and Saeed Babaee

Dyes and Pigments, 2015, 123, 222
DOI: 10.1016/j.dyepig.2015.08.009

SO3H-dendrimer functionalized magnetic nanoparticles (Fe3O4@D NH (CH2)4SO3H): Synthesis, characterization and its application as a novel and heterogeneous catalyst for the one-pot synthesis of polyfunctionalized pyrans and polyhydroquinolines

Behrooz Maleki, Oliver Reiser, Ehsan Esmaeilnezhad and Hyoung Jin Choi

Polyhedron, 2019, 162, 129
DOI: 10.1016/j.poly.2019.01.055

Efficient synthesis of quinazoline derivatives catalyzed by flourinated alcohol

Behrooz Maleki and Akram Vedad Mofrad

Res Chem Intermed, 2017, 43, 3111
DOI: 10.1007/s11164-016-2813-3

Multicomponent synthesis of spiroannulated hybrid molecules with preferred substructures using indium triflate as a sustainable catalyst

Asha Verma, Sandeep Kumar, Vineeta Khatri, Gargi Pathak and Dinesh Kumar Arya

Res Chem Intermed, 2024, 50, 251
DOI: 10.1007/s11164-023-05177-2

Solvent-free, sonochemical, one-pot, four-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones and 1H-pyrazolo[1,2-b]phthalazine-diones catalyzed by Fe3O4@SiO2-imid-PMAn magnetic nanoparticles

Mohsen Esmaeilpour, Jaber Javidi, Fatemeh Nowroozi Dodeji and Saeed Zahmatkesh

Res Chem Intermed, 2021, 47, 2629
DOI: 10.1007/s11164-016-2462-6

Cellulose nanofibers (CNFs) from lignocellulose biomass of waste sugarcane bagasse (SCB): an environmentally green nanocatalyst for the one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

Hoda Baharipour, Maryam Deinavizadeh and Ali Reza Kiasat

Polymer, 2025, 334, 128697
DOI: 10.1016/j.polymer.2025.128697

HFIP in Organic Synthesis

Hashim F. Motiwala, Ahlam M. Armaly, Jackson G. Cacioppo, Thomas C. Coombs, Kimberly R. K. Koehn, Verrill M. Norwood and Jeffrey Aubé

Chem. Rev., 2022, 122, 12544
DOI: 10.1021/acs.chemrev.1c00749

Synthesis, anticancer for prostate cancer cells and antibacterial activity of new diazepine derivatives

Nahla Ghaze Fahad, Noor H. Imran, Hussein Ali Kadhim Kyhoiesh and Mohammed K. Al-Hussainawy

Results in Chemistry, 2023, 6, 101049
DOI: 10.1016/j.rechem.2023.101049

One-Pot Synthesis of 2H-Indazolo[1,2-b]phthalazine-1,6,11(13H)-trione Derivatives Using Nano Hybrid MoO3/α-Al2O3

Behrooz Maleki, Samaneh Sedigh Ashrafi and Reza Tayebee

Organic Preparations and Procedures International, 2017, 49, 542
DOI: 10.1080/00304948.2017.1384260

Deep eutectic solvent an efficient reaction medium for the synthesis of chromeno pyrazolo and indazolo phthalazine derivatives

Audumbar Patil, Trushant Lohar, Ananda Mane, Siddharth Kamat and Rajashri Salunkhe

Journal of Heterocyclic Chem, 2019, 56, 3145
DOI: 10.1002/jhet.3713

1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) as a reusable promoting medium for the catalyst-free and green synthesis of dihydropyrano[2,3-c]pyrazole scaffolds

Farzaneh Mohamadpour

Results in Chemistry, 2024, 9, 101629
DOI: 10.1016/j.rechem.2024.101629

Synthesis of 1 H -Pyrazolo[1,2- b ]Phthalazine-5,10-Dione and 1 H -Pyrazolo[1,2- a ]Pyridazine-5,8-Dione Derivatives by Bovine Serum Albumin in Water

Alireza Farahanipour, Hossein Bavandi, Mansour Shahedi and Zohreh Habibi

Polycyclic Aromatic Compounds, 2023, 43, 7042
DOI: 10.1080/10406638.2022.2128829

A novel heterogeneous biocatalyst based on graphene oxide for synthesis of pyran derivatives

Leila Amiri-Zirtol and Soghra Khabnadideh

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-57682-y

Synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives in a reusable catalyst/solvent; 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)

Farzaneh Mohamadpour

Current Research in Green and Sustainable Chemistry, 2024, 9, 100427
DOI: 10.1016/j.crgsc.2024.100427

Fabrication of Copper(II)-coated Magnetic Core-shell Nanoparticles an Engineered Nano-magnetic Catalyst for the Synthesis of Pyrano Pyrazole and Pyrazole Derivatives

Maryam Soleimani, Tahereh Akbarpour and Ardeshir Khazaei

Polycyclic Aromatic Compounds, 2024, 44, 90
DOI: 10.1080/10406638.2023.2169472

One-pot Synthesis of Polysubstituted Imidazoles Catalyzed by an Ionic liquid

Behrooz Maleki, Golnoosh Esmailian Kahoo and Reza Tayebee

Organic Preparations and Procedures International, 2015, 47, 461
DOI: 10.1080/00304948.2015.1088757

Preparation, characterization and catalytic activity of dendrimer-encapsulated phosphotungstic acid nanoparticles immobilized on nanosilica for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free or sonochemical conditions

Mohsen Esmaeilpour, Jaber Javidi and Farzaneh Dehghani

J IRAN CHEM SOC, 2016, 13, 695
DOI: 10.1007/s13738-015-0782-x

One-pot synthesis of some 2-amino-4H-chromene derivatives using triethanolamine as a novel reusable organocatalyst under solvent-free conditions and its application in electrosynthesis of silver nanoparticles

B. Maleki, M. Baghayeri, S. Sheikh, S. Babaee and S. Farhadi

Russ J Gen Chem, 2017, 87, 1064
DOI: 10.1134/S1070363217050280

Ionic liquid functionalized magnetic organosilica nanocomposite: A powerful and efficient support for manganese catalyst

Maryam Neysi, Dawood Elhamifar and Meysam Norouzi

Materials Chemistry and Physics, 2020, 243, 122589
DOI: 10.1016/j.matchemphys.2019.122589

A green and one-pot synthesis of 6-amino-1,4-dihydropyrano[2,3-c]-pyrazole-5-carbonitrile derivatives using CoCeO2 nanoparticles as an efficient, reusable and heterogeneous catalyst

Shaheen A. Shaikh, Vishal S. Kamble, Rohan K. Zemase, Sanjay K. Patil and Balasaheb D. Aghav

Res Chem Intermed, 2023, 49, 5255
DOI: 10.1007/s11164-023-05156-7

One pot multicomponent synthesis of highly substituted imidazoles using tetrabutylammonium peroxy disulfate as a catalyst

Ramesh Nukala, Kumaraswamy Gullapelli and Ramaiah Konakanchi

Res Chem Intermed, 2023, 49, 4713
DOI: 10.1007/s11164-023-05090-8