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Richa Goel, Vijay Luxami and Kamaldeep Paul

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Synthesis of phenstatin/isocombretastatin–chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers

Ahmed Kamal, G. Bharath Kumar, M. V. P. S. Vishnuvardhan, Anver Basha Shaik, Vangala Santhosh Reddy, Rasala Mahesh, Ibrahim Bin Sayeeda and Jeevak Sopanrao Kapure

Org. Biomol. Chem., 2015, 13, 3963
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Imidazopyrimidine: from a relatively exotic scaffold to an evolving structural motif in drug discovery

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RSC Med. Chem., 2024, 15, 1488
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Novel sulfonamides unveiled as potent anti-lung cancer agents via tumor pyruvate kinase M2 activation

Rudradip Das, Deep Rohan Chatterjee, Saumya Kapoor, Het Vyas and Amit Shard

RSC Med. Chem., 2024, 15, 3070
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In vivo assessment of newly synthesized achiral copper(ii) and zinc(ii) complexes of a benzimidazole derived scaffold as a potential analgesic, antipyretic and anti-inflammatory

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RSC Adv., 2016, 6, 19475
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A short GC rich DNA derived from microbial origin targets tubulin/microtubules and induces apoptotic death of cancer cells

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Design, synthesis and biological evaluation of imidazopyridine–propenone conjugates as potent tubulin inhibitors

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Application of “smart” multifunctional nanoprobes in tumor diagnosis and treatment

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Diversity oriented synthesis of benzimidazole-based biheterocyclic molecules by combinatorial approach: a critical review

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Balancing the molecular twist and conformational rigidity in imidazo[1,2-a]pyridines to achieve dual-state emissive (DSE) luminogens for applications in OLEDs and cell-imaging

Chinmay Thakkar, Seemantini Kale, Mohammad Amir Ahemad, Monalisa Debnath, Anjali Tripathi, Saona Seth, Purav Badani, Rohit Srivastava, Sangita Bose and Satyajit Saha

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An Insight into the Structure-activity Relationship of Benzimidazole and Pyrazole Derivatives as Anticancer Agents

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Cobalt Coordination Polymers Offering Hydrogen Bonding Cavities as Efficient Catalysts for Coupling Reactions

Sanya Pachisia, Hina Goyal, Aashish, Gulshan Kumar and Rajeev Gupta

ChemCatChem, 2024, 16
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Synthesis and biological evaluation of novel amide derivatives of 1,2,4-oxadiazole-imidazopyridines as anticancer agents

Ramesh Boddiboyena, G Nagendra Reddy, Naresh varma Seelam, Monima Sarma, Deepti Kolli, M. Rajeswari and Mura reddy Gudisela

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Synthesis and biological evaluation of novel imidazopyrimidin‐3‐amines as anticancer agents

Mohammad Mahdavi, Shima Dianat, Behnaz Khavari, Setareh Moghimi, Mohammad Abdollahi, Maliheh Safavi, Arash Mouradzadegun, Sussan Kabudanian Ardestani, Reyhaneh Sabourian, Saeed Emami, Tahmineh Akbarzadeh, Abbas Shafiee and Alireza Foroumadi

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DNA/BSA Binding, Molecular Docking, Nuclease Activity and Cytotoxicity Studies of Hydrazide Based Schiff Base Complexes

Muthiah Chinnasamy and Andy Ramu

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Synthesis of 3-N-/O-/S-methyl-imidazo[1,2-a] pyridine derivatives for caspase-3 mediated apoptosis induced anticancer activity

Davinder Singh, Tenzen Yodun, Gulshan Kumar, Javeed Ahmad Tali, Harshita Tiwari, Jasvinder Singh, Amit Nargotra, Abhilash Samykutty, Shashank Singh and Ravi Shankar

Bioorganic Chemistry, 2022, 125, 105882
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Exploration of benzimidazoles as potential microtubule modulators: An insight in the synthetic and therapeutic evolution

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La(III), Ce(III), Pr(III) and Eu(III) complexes with fenamic acid based ligands: preparation, spectral and thermal analysis and evaluation of their cytotoxicity in MDA-MB-231 breast cancer cells

Hanan K. Mosbah, Ahmed B. M Ibrahim, Amna S. A. Zidan, Aref A. M. Aly and Saber H. Saber

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Synthesis and anticancer evaluation of benzo-N-heterocycles transition metal complexes against esophageal cancer cell lines

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Mechanistic Investigation of Thiazole-Based Pyruvate Kinase M2 Inhibitor Causing Tumor Regression in Triple-Negative Breast Cancer

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CuI/Fe3O4 NPs@Biimidazole IL‐KCC‐1 as a leach proof nanocatalyst for the synthesis of imidazo[1,2‐a]pyridines in aqueous medium

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Synthesis and evaluation of novel $N,N'$-disubstituted benzimidazolium bromides salts as antitumor agents

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Imidazopyridine linked triazoles as tubulin inhibitors, effectively triggering apoptosis in lung cancer cell line

Ibrahim Bin Sayeed, M.V.P.S. Vishnuvardhan, Apoorva Nagarajan, Srinivas Kantevari and Ahmed Kamal

Bioorganic Chemistry, 2018, 80, 714
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Novel 3-aminoimidazole[1,2-α]pyridine/pyrazine analogues: Synthesis and biological evaluation as anticancer agents

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Discovery of a novel selective water-soluble SMAD3 inhibitor as an antitumor agent

Nannan Wu, Guangyu Lian, Jingyi Sheng, Dan Wu, Xiyong Yu, Huiyao Lan, Wenhui Hu and Zhongjin Yang

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Synthesis of Imidazo[1,2‐a]pyridines: C‐H Functionalization in the Direction of C‐S Bond Formation

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The Chemical Record, 2017, 17, 1019
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Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents

Heba T. Abdel‐Mohsen, Amira Abood, Keith J. Flanagan, Alina Meindl, Mathias O. Senge and Hoda I. El Diwani

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Design, synthesis, and biological evaluation of chalcone-linked thiazole-imidazopyridine derivatives as anticancer agents

Vellanki Ragha Suma, Reddymasu Sreenivasulu, Mandava Venkata Basaveswara Rao, Madala Subramanyam, Mohamed Jawed Ahsan, Ramesh Alluri and Kuppili Ram Mohan Rao

Med Chem Res, 2020, 29, 1643
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Novel imidazopyrimidines-based molecules induce tetramerization of tumor pyruvate kinase M2 and exhibit potent antiproliferative profile

Sagarkumar Patel, Christoph Globisch, Priyanka Pulugu, Prasoon Kumar, Alok Jain and Amit Shard

European Journal of Pharmaceutical Sciences, 2022, 170, 106112
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Synthesis, Characterization, and In Vivo Anti-Cancer Activity of New Metal Complexes Derived from Isatin-N(4)antipyrinethiosemicarbazone Ligand Against Ehrlich Ascites Carcinoma Cells

Fathy El-Saied, Bishoy El-Aarag, Tarek Salem, Ghada Said, Shaden A. M. Khalifa and Hesham R. El-Seedi

Molecules, 2019, 24, 3313
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Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents

Manohar Mantipally, Madhusudhana Reddy Gangireddy, Rambabu Gundla, Vishnu Nayak Badavath, Santhosh Reddy Mandha and Venkatanarayana Chowdary Maddipati

Bioorganic & Medicinal Chemistry Letters, 2019, 29, 2248
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Synthesis, crystal structures and spectral characterization of imidazo[1,2-a]pyrimidin-2-yl-acetic acid and related analog with imidazo[2,1-b]thiazole ring

Agnieszka Dylong, Waldemar Goldeman, Michał Sowa, Katarzyna Ślepokura, Piotr Drożdżewski and Ewa Matczak-Jon

Journal of Molecular Structure, 2016, 1117, 153
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In vitro, in vivo and in silico-driven identification of novel benzimidazole derivatives as anticancer and anti-inflammatory agents

Reshma Sathyanarayana, Boja Poojary, Sudhanva M. Srinivasa, Vijay K. Merugumolu, Revanasiddappa B. Chandrashekarappa and Shobith Rangappa

J IRAN CHEM SOC, 2022, 19, 1301
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A comprehensive review on pyrazoline based heterocyclic hybrids as potent anticancer agents

Kashif Haider, Mohd Shafeeque, Shaikh Yahya and M. Shahar Yar

European Journal of Medicinal Chemistry Reports, 2022, 5, 100042
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Green synthesis of imidazo[1,2-a]pyridines using calix[6]arene-SO3H surfactant in water

Mahshid Esmaielzade Rostami, Banafsheh Gorji and Reza Zadmard

Tetrahedron Letters, 2018, 59, 2393
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Synthesis and anticancer activity evaluation of some novel imidazo[1,2- a ]pyridine based heterocycles containing S -alkyl/aryl moiety

Betül Kaya, Leyla Yurttaş, Merve Baysal, Büşra Korkut Çelikateş, Zafer Asım Kaplancıklı and Rizvan İmamoğlu

Phosphorus, Sulfur, and Silicon and the Related Elements, 2024, 199, 383
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Solvent and catalyst‐free synthesis of imidazo[1,2‐a]pyridines by grindstone chemistry

Kumar Godugu and Chinna Gangi Reddy Nallagondu

Journal of Heterocyclic Chem, 2021, 58, 250
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Design, synthesis, biological evaluations, molecular docking, and in vivo studies of novel phthalimide analogs

Magdy A. H. Zahran, Bishoy El‐Aarag, Ahmed B. M. Mehany, Amany Belal and Ali S. Younes

Archiv der Pharmazie, 2018, 351
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Pyrazole‐Imidazopyridine Hydrazones: Synthesis, α‐Glucosidase, α‐Amylase Inhibitory Activity and Computational Studies

Ganavi D, Shashank M. Patil, Vasantha Kumar, Ramith Ramu and Boja Poojary

ChemistrySelect, 2023, 8
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Imidazole and Biphenyl Derivatives as Anti-cancer Agents for Glioma Therapeutics: Computational Drug Repurposing Strategy

Poornimaa Murali and Ramanathan Karuppasamy

ACAMC, 2023, 23, 1085
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Synthesis and cytotoxic/antimicrobial screening of 2-alkenylimidazo[1,2-a]pyrimidines

Ángel Ramírez-Trinidad, Karol Carrillo-Jaimes, José A. Rivera-Chávez and Eduardo Hernández-Vázquez

Med Chem Res, 2023, 32, 144
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Design and Synthesis of Piperazine‐Linked Imidazo[1,2‐a]pyridine Derivatives as Potent Anticancer Agents

Madhusudhana Reddy Gangireddy, Manohar Mantipally, Rambabu Gundla, Vishnu Nayak Badavath, Kalyani Paidikondala and Anilkumar Yamala

ChemistrySelect, 2019, 4, 13622
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Synthesis and biological evaluation of imidazo[2,1-b]thiazole-benzimidazole conjugates as microtubule-targeting agents

Mirza Feroz Baig, V. Lakshma Nayak, Prasad Budaganaboyina, Kishore Mullagiri, Satish Sunkari, Jitendra Gour and Ahmed Kamal

Bioorganic Chemistry, 2018, 77, 515
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Hypervalent iodine(III) catalyzed rapid and efficient access to benzimidazoles, benzothiazoles and quinoxalines: Biological evaluation of some new benzimidazole-imidazo[1,2-a]pyridine conjugates

P.V. Sri Ramya, Srinivas Angapelly, Routhu Sunitha Rani, Chander Singh Digwal, C. Ganesh Kumar, Bathini Nagendra Babu, Lalita Guntuku and Ahmed Kamal

Arabian Journal of Chemistry, 2020, 13, 120
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Self-assembled organic nanoparticles of benzimidazole analogue exhibit enhanced uptake in 3D tumor spheroids and oxidative stress induced cytotoxicity in breast cancer

Vandna Dhanwal, Archana Katoch, Amanpreet Singh, Souneek Chakraborty, Mir Mohd Faheem, Gaganpreet Kaur, Debasis Nayak, Narinder Singh, Anindya Goswami and Navneet Kaur

Materials Science and Engineering: C, 2019, 97, 467
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Biological evaluation of redox stable cisplatin/Cu(II)-DNA adducts as potential anticancer agents

Sellamuthu Kathiresan, Raman Dhivya, Murugesan Vigneshwar, Marichamy Rajasekaran, Jyothi Ranjani, Jeyaprakash Rajendhran, Sankaran Srinivasan, Subramanian Mugesh, Maruthamuthu Murugan, Periakaruppan Athappan and Jamespandi Annaraj

Journal of Coordination Chemistry, 2016, 69, 238
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K2CO3-nanoparticles catalyzed the synthesis of 3-arylidine imidazo[1,2-c]pyrimidine candidates: Cytotoxic activity and docking study

Samar. M. Mohammed, Asmaa A. Masry, Ahmed H. Moustafa, Hassan A. El-Sayed, Emad M. Gad and Hesham A. Morsy

Synthetic Communications, 2023, 53, 1319
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Synthetic Methodologies of Imidazo[1,2-a]Pyrimidine: A Review

Parteek Prasher, Mousmee Sharma, Kousar Jahan, William N. Setzer and Javad Sharifi-Rad

Chemistry Africa, 2025, 8, 1
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Use of Imidazo[1,2‐a]pyridine as a Carbonyl Surrogate in a Mannich‐Like, Catalyst Free, One‐Pot Reaction

Gunaganti Naresh, Naga Rajiv Lakkaniga, Anupreet Kharbanda, Wei Yan, Brendan Frett and Hong‐yu Li

Eur J Org Chem, 2019, 2019, 770
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Synthesis, Characterization, and Antiproliferative Activity Studies of Novel Benzimidazole‐Imidazopyridine Hybrids as DNA Groove Binders

Bahar Caymaz, Ufuk Yıldız, Senem Akkoç, Zuhal Gerçek, Abdurrahman Şengül and Burak Coban

ChemistrySelect, 2020, 5, 8465
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Synthesis of novel benzimidazole-based retrochalcones and their anticancer activity against breast and colon cancer

Aboudramane Koné, Coulibaly Souleymane, Mabintou Kalo, Camara Tchambaga Etienne, Sylvain Collet and Drissa Sissouma

Synthetic Communications, 2025, 55, 175
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Synthesis and biological activities of 3-aminoimidazo[1,2-α]pyridine compounds

Isra Al-Qadi, Michel Hanania, Ismail Warad, Nisreen Al-Hajj, Rand Hazzam, Yousef Salama, Saki Raheem and Nawaf Al-Maharik

BMC Chemistry, 2025, 19
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Comprehensive exploration of novel imidazopyrimidine derivatives: Design, synthesis, computational assessment, and anti-breast cancer activity

Sagarkumar Patel, Priyanka Pulugu, Rudradip Das, Moumita Ghosh Chowdhury, Deep Rohan Chatterjee, Akshay Srivastava and Amit Shard

Journal of Molecular Structure, 2025, 1326, 141062
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Synthesis of novel imidazo[1,2-a]pyridine-4-hydroxy-2H-coumarins by Groebke–Blackburn–Bienaymé multicomponent reaction as potential NS5B inhibitors

Parth Manvar, Faraz Shaikh, Rajesh Kakadiya, Krunal Mehariya, Ranjan Khunt, Bipin Pandey and Anamik Shah

Tetrahedron, 2016, 72, 1293
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Design, synthesis and molecular docking of piperidin‐4‐amine linked pyrimidine derivatives as potent anticancer agents

Madhu Sudhana Reddy Gangireddy, Manohar Mantipally, Vishnu Nayak Badavath, Venkatanarayana Chowdary Maddipati, Kalyani Paidikondala, Naresh Kumar Katari and Rambabu Gundla

Chemical Data Collections, 2021, 32, 100646
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