A large-scale study of ionic liquids employed in chemistry and energy research to reveal cytotoxicity mechanisms and to develop a safe design guide

Lilya U. Dzhemileva, Vladimir A. D'yakonov, Marina M. Seitkalieva, Natalia S. Kulikovskaya, Ksenia S. Egorova and Valentine P. Ananikov

Green Chem., 2021, 23, 6414
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Aromatic long chain cations of amphiphilic ionic liquids permeabilise the inner mitochondrial membrane and induce mitochondrial dysfunction at cytotoxic concentrations

Meryem-Nur Duman, Alexander Angeloski, Michael S. Johnson and Tristan Rawling

Green Chem., 2023, 25, 6067
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Design of carboxylate-based ionic liquids (ILs) containing OH and CF3 groups; influence of intramolecular hydrogen bonds and inductive effect on the binding energy between the cation and anion of ILs, a DFT study

Sepideh Kalhor and Alireza Fattahi

New J. Chem., 2021, 45, 4710
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Structure–antitumor activity relationships of tripodal imidazolium-amino acid based salts. Effect of the nature of the amino acid, amide substitution and anion

Adriana Valls, Belén Altava, Vladimir Aseyev, Israel Carreira-Barral, Laura Conesa, Eva Falomir, Eduardo García-Verdugo, Santiago Vicente Luis and Roberto Quesada

Org. Biomol. Chem., 2021, 19, 10575
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Structural, spectral and biological studies of (E)-2-((2-(benzo[d]thiazol-2-yl)hydrazineylidene)methyl)-4,6-dibromophenol (HL) and its metal complexes of Mn(II), Cu(II), Co(II), Ni(II), and Zn(II)

Abdul Majeed Ganai, Kamble Gopichand, N. Nageswara Rao, R. Nagaraju, Ahmed kamal and P. Venkateswar Rao

Results in Chemistry, 2023, 6, 101001
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Novel 3-Methyl-2-alkylthio Benzothiazolyl-Based Ionic Liquids: Synthesis, Characterization, and Antibiotic Activity

Teng Zhang, Hao He, Jun Du, Zhi He and Shun Yao

Molecules, 2018, 23, 2011
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A Flexible Strategy for Modular Synthesis of Curcuminoid‐BF2/Curcuminoid Pairs and Their Comparative Antiproliferative Activity in Human Cancer Cell Lines

Rodrigo Abonia, Kenneth K. Laali, Dawn Raja Somu, Scott D. Bunge and Esther C. Wang

ChemMedChem, 2020, 15, 354
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Spectroscopic exploration of binding of new imidazolium-based palladium(II) saldach complexes with CT-DNA as anticancer agents against HER2/neu overexpression

Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Hani S. Hafez and Reda F.M. Elshaarawy

Journal of Molecular Structure, 2019, 1191, 118
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A Profile of the In Vitro Anti-Tumor Activity and In Silico ADME Predictions of Novel Benzothiazole Amide-Functionalized Imidazolium Ionic Liquids

Fawzia Al-blewi, Nadjet Rezki, Arshi Naqvi, Husna Qutb Uddin, Salsabeel Al-Sodies, Mouslim Messali, Mohamed Reda Aouad and Sanaa Bardaweel

IJMS, 2019, 20, 2865
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New pyridine‐based chalcones and pyrazolines with anticancer, antibacterial, and antiplasmodial activities

Jonathan Ramírez‐Prada, Juan S. Rocha‐Ortiz, Marta I. Orozco, Pedro Moreno, Miguel Guevara, Mauricio Barreto, Maria E. Burbano, Sara Robledo, Maria del Pilar Crespo‐Ortiz, Jairo Quiroga, Rodrigo Abonia, Viviana Cuartas and Braulio Insuasty

Archiv der Pharmazie, 2024
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Appraisal of 1‐Butylimidazole‐Derived Ionic Liquids as Anthelmintic Agents: An Experimental and In Silico Approach

Prabodh Ranjan, Mohd Athar, Hilal Rather, Kari Vijayakrishna, Rajesh Vasita and Prakash C. Jha

ChemistrySelect, 2018, 3, 7518
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Effects of ionic liquids on biomembranes: A review on recent biophysical studies

Saheli Mitra, Veerendra K. Sharma and Sajal K. Ghosh

Chemistry and Physics of Lipids, 2023, 256, 105336
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Synthesis of novel quinoline–based 4,5–dihydro–1 H –pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents

Jonathan Ramírez–Prada, Sara M. Robledo, Iván D. Vélez, María del Pilar Crespo, Jairo Quiroga, Rodrigo Abonia, Alba Montoya, Laura Svetaz, Susana Zacchino and Braulio Insuasty

European Journal of Medicinal Chemistry, 2017, 131, 237
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Development and medical application of ionic liquid-based transdermal formulations

Taro Shimizu, Hidetoshi Hamamoto and Tatsuhiro Ishida

DDS, 2023, 38, 230
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Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product

Cary F. C. Lam, Melissa M. Cadelis and Brent R. Copp

Marine Drugs, 2020, 18, 404
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Deciphering the anthelmintic activity of benzimidazolium salts by experimental and in-silico studies

Prabodh Ranjan, Mohd Athar, Kari Vijayakrishna, Lalit K. Meena, Rajesh Vasita and Prakash C. Jha

Journal of Molecular Liquids, 2018, 268, 156
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Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine

Ksenia S. Egorova, Evgeniy G. Gordeev and Valentine P. Ananikov

Chem. Rev., 2017, 117, 7132
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Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling

Ana S. C. Valdeira, Daniel A. Ritt, Deborah K. Morrison, James B. McMahon, Kirk R. Gustafson and Jorge A. R. Salvador

Front. Chem., 2018, 6
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Synthesis, characterization and antimicrobial activities of benzothiazole-imino-benzoic acid ligands and their Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes

Neha Mishra, Surendra Singh Gound, Rajesh Mondal, Ritu Yadav and Rampal Pandey

Results in Chemistry, 2019, 1, 100006
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Imidazolium-Based Ionic Liquids Affect Morphology and Rigidity of Living Cells: An Atomic Force Microscopy Study

Massimiliano Galluzzi, Carsten Schulte, Paolo Milani and Alessandro Podestà

Langmuir, 2018, 34, 12452
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Thermodynamics and structure of model bio-membrane of liver lipids in presence of imidazolium-based ionic liquids

Saheli Mitra, Veerendra Kumar Sharma, Jyotsna Bhatt Mitra, Subhadip Chowdhury, Mrinmay Kumar Mukhopadhyay, Ramaprasad Mukhopadhyay and Sajal Kumar Ghosh

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2021, 1863, 183589
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Ionic Liquid-Like Pharmaceutical Ingredients and Applications of Ionic Liquids in Medicinal Chemistry: Development, Status and Prospects

Jie Tang, Hang Song, Xueting Feng, Alula Yohannes and Shun Yao

CMC, 2019, 26, 5947
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Synergistic/antagonistic cytotoxic effects in mixtures of ionic liquids with doxorubicin or mitoxantrone

Ksenia S. Egorova, Alexandra V. Posvyatenko, Artem N. Fakhrutdinov, Alexey S. Galushko, Marina M. Seitkalieva and Valentine P. Ananikov

Journal of Molecular Liquids, 2021, 323, 114870
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Improved anticancer and antiparasitic activity of new lawsone Mannich bases

Katharina Mahal, Aamir Ahmad, Florian Schmitt, Julia Lockhauserbäumer, Kathrin Starz, Rohan Pradhan, Subhash Padhye, Fazlul H. Sarkar, Waleed S. Koko, Rainer Schobert, Klaus Ersfeld and Bernhard Biersack

European Journal of Medicinal Chemistry, 2017, 126, 421
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Pentacyclic Triterpenoids-Based Ionic Compounds: Synthesis, Study of Structure–Antitumor Activity Relationship, Effects on Mitochondria and Activation of Signaling Pathways of Proliferation, Genome Reparation and Early Apoptosis

Lilya U. Dzhemileva, Regina A. Tuktarova, Usein M. Dzhemilev and Vladimir A. D’yakonov

Cancers, 2023, 15, 756
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Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids

Adriana Valls, Jose J. Andreu, Eva Falomir, Santiago V. Luis, Elena Atrián-Blasco, Scott G. Mitchell and Belén Altava

Pharmaceuticals, 2020, 13, 482
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Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

Katherine Zlotkowski, William M. Hewitt, Pengcheng Yan, Heidi R. Bokesch, Megan L. Peach, Marc C. Nicklaus, Barry R. O’Keefe, James B. McMahon, Kirk R. Gustafson and John S. Schneekloth

Org. Lett., 2017, 19, 1726
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Mechanisms of action of ionic liquids on living cells: the state of the art

Pallavi Kumari, Visakh V.S. Pillai and Antonio Benedetto

Biophys Rev, 2020, 12, 1187
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Design, synthesis, and molecular docking study of novel quinoline‐based bis‐chalcones as potential antitumor agents

Daniel Insuasty, Stephanie García, Rodrigo Abonia, Braulio Insuasty, Jairo Quiroga, Manuel Nogueras, Justo Cobo, Gabriela L. Borosky and Kenneth K. Laali

Archiv der Pharmazie, 2021, 354
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Novel Anticancer NHC*-Gold(I) Complexes Inspired by Lepidiline A

Danielle Curran, Helge Müller-Bunz, Sofia I. Bär, Rainer Schobert, Xiangming Zhu and Matthias Tacke

Molecules, 2020, 25, 3474
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Synthesis, Cytotoxicity, and α-glucosidase Inhibitory Activity of Triterpenic and Sitosterol Tetrazole Derivatives

Anastasiya V. Petrova, Alexander I. Poptsov, Ha Nguyen Thi Thu, Nguyen Van Tuyen, Elmira F. Khusnutdinova, Denis A. Babkov and Oxana B. Kazakova

Chem Heterocycl Comp, 2021, 57, 920
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Mechanisms of Biological Effects of Ionic Liquids: From Single Cells to Multicellular Organisms

Ksenia S. Egorova, Alexey V. Kibardin, Alexandra V. Posvyatenko and Valentine P. Ananikov

Chem. Rev., 2024, 124, 4679
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Rational design of imidazolium based salts as anthelmintic agents

Prabodh Ranjan, Mohd Athar, H. Rather, Kari Vijayakrishna, R. Vasita and Prakash C. Jha

Journal of Molecular Liquids, 2018, 255, 578
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A Schmidt rearrangement-mediated synthesis of novel tetrahydro-benzo[1,4]diazepin-5-ones as potential anticancer and antiprotozoal agents

Daniel Insuasty, Sara M. Robledo, Iván D. Vélez, Paola Cuervo, Braulio Insuasty, Jairo Quiroga, Manuel Nogueras, Justo Cobo and Rodrigo Abonia

European Journal of Medicinal Chemistry, 2017, 141, 567
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An efficient route to unsymmetrical bis(azolium) salts: CCC-NHC pincer ligand complex precursors

Hannah K. Box, Tyler O. Howell, William E. Kennon, Griffin A. Burk, Henry U. Valle and T. Keith Hollis

Tetrahedron, 2017, 73, 2191
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Synthesis, photophysical behavior and biomolecular reactivity of new triphenylphosphonium-based Pd(II)salphens as new anticancer candidates

Mohammad Y. Alfaifi, Mohamed A.-E. Zein, Ali A. Shati, Mohammed A. Alshehri, Serag Eldin I. Elbehairi, Hani S. Hafez and Reda F.M. Elshaarawy

Journal of Photochemistry and Photobiology A: Chemistry, 2019, 385, 112083
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Synthesis of New Thieno[2,3-d]pyrimidines Containing a 1,2,3-Triazole Ring and Their Therapeutic Response in NCI-60 Cell Line Panel

K. A. Bhensdadia, N. H. Lalavani and S. H. Baluja

Russ J Org Chem, 2021, 57, 1668
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