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A bodipy based dual functional probe for the detection of hydrogen sulfide and H2S induced apoptosis in cellular systems
Neha Gupta, Shahi Imam Reja, Vandana Bhalla, Muskan Gupta, Gurcharan Kaur and Manoj Kumar
Chem. Commun., 2015, 51, 10875
DOI: 10.1039/C5CC02984H

A prototype reversible polymersome-stabilized H2S photoejector operating under pseudophysiological conditions
A. Tron, A. Peyret, J. Thevenot, R. Bofinger, S. Lecommandoux and N. D. McClenaghan
Org. Biomol. Chem., 2016, 14, 6394
DOI: 10.1039/C6OB01155A

Tetraphenylethylene conjugated p-hydroxyphenacyl: fluorescent organic nanoparticles for the release of hydrogen sulfide under visible light with real-time cellular imaging
C. Parthiban, Pavithra M., L. Vinod Kumar Reddy, Dwaipayan Sen, Melvin Samuel S. and N. D. Pradeep Singh
Org. Biomol. Chem., 2018, 16, 7903
DOI: 10.1039/C8OB01629A

A novel H2S releasing-monastrol hybrid (MADTOH) inhibits L-type calcium channels
Taniris Cafiero Braga, Itamar Couto Guedes de Jesus, Kathleen Viveiros Soares, Silvia Guatimosim, Leonardo da Silva Neto, Cristiane Jovelina da-Silva, Luzia Valentina Modolo, José Evaldo Rodrigues Menezes Filho, Paula Rhana, Jader Santos Cruz and Ângelo de Fátima
New J. Chem., 2021, 45, 671
DOI: 10.1039/D0NJ04415F

Highly efficient H2S scavengersviathiolysis of positively-charged NBD amines
Ismail Ismail, Zhuoyue Chen, Lu Sun, Xiuru Ji, Haishun Ye, Xueying Kang, Haojie Huang, Haibin Song, Sarah G. Bolton, Zhen Xi, Michael D. Pluth and Long Yi
Chem. Sci., 2020, 11, 7823
DOI: 10.1039/D0SC01518K

Controlled release of hydrogen sulfide significantly reduces ROS stress and increases dopamine levels in transgenic C. elegans
Rafat Ali, Hilal Ahmad Pal, Rohil Hameed, Aamir Nazir and Sandeep Verma
Chem. Commun., 2019, 55, 10142
DOI: 10.1039/C9CC05153H

Fluorogenic hydrogen sulfide (H2S) donors based on sulfenyl thiocarbonates enable H2S tracking and quantification
Yu Zhao, Matthew M. Cerda and Michael D. Pluth
Chem. Sci., 2019, 10, 1873
DOI: 10.1039/C8SC05200J

The benefits of macromolecular hydrogen sulfide prodrugs
Luke A. Connal
J. Mater. Chem. B, 2018, 6, 7122
DOI: 10.1039/C8TB02352B

Small molecule generators of biologically reactive sulfur species
Prerona Bora, Preeti Chauhan, Kundansingh A. Pardeshi and Harinath Chakrapani
RSC Adv., 2018, 8, 27359
DOI: 10.1039/C8RA03658F

Regulating H2S release from self-assembled peptide H2S-donor conjugates using cysteine derivatives
Zhao Li, Marius Thomas, Christian M. Berač, Oliver S. Stach, Pol Besenius and John B. Matson
Org. Biomol. Chem., 2024, 22, 8173
DOI: 10.1039/D4OB01148A

Enzyme-responsive hybrid prodrug of nitric oxide and hydrogen sulfide for heart failure therapy
Qi Liu, Guangbo Ji, Yushu Chu, Tian Hao, Meng Qian and Qiang Zhao
Chem. Commun., 2022, 58, 7396
DOI: 10.1039/D2CC02267B

Hydrogen sulfide-releasing polyurethane/gelatin/keratin–TA conjugate mats for wound healing
Xiao Han, Lijuan Wang, Yushang Shang, Xu Liu, Jiang Yuan and Jian Shen
J. Mater. Chem. B, 2022, 10, 8672
DOI: 10.1039/D2TB01700H

Rapid generation of HNO induced by visible light
G. Carrone, J. Pellegrino and F. Doctorovich
Chem. Commun., 2017, 53, 5314
DOI: 10.1039/C7CC02186K

A computational study on H2S release and amide formation from thionoesters and cysteine
Yuan-Ye Jiang, Ling Zhu, Xia Fan, Qi Zhang, Ya-Jie Fu, He Li, Bing Hu and Siwei Bi
Org. Biomol. Chem., 2019, 17, 5771
DOI: 10.1039/C9OB00854C

Bio-orthogonal “click-and-release” donation of caged carbonyl sulfide (COS) and hydrogen sulfide (H2S)
Andrea K. Steiger, Yang Yang, Maksim Royzen and Michael D. Pluth
Chem. Commun., 2017, 53, 1378
DOI: 10.1039/C6CC09547J

Quinoline H2S donor decorated fluorescent carbon dots: visible light responsive H2S nanocarriers
Manoranjan Bera, Somnath Maji, Amrita Paul, Bikash Kumar Sahoo, Tapas Kumar Maiti and N. D. Pradeep Singh
J. Mater. Chem. B, 2020, 8, 1026
DOI: 10.1039/C9TB02157D

Reactive films fabricated using click sulfur(vi)–fluoride exchange reactions via layer-by-layer assembly
Shengjie Liu, Yanping Cao, Zhaoqiang Wu and Hong Chen
J. Mater. Chem. B, 2020, 8, 5529
DOI: 10.1039/D0TB00908C

Electrochemical hydrogen sulfide biosensors
Tailin Xu, Nikki Scafa, Li-Ping Xu, Shufeng Zhou, Khalid Abdullah Al-Ghanem, Shahid Mahboob, Bunshi Fugetsu and Xueji Zhang
Analyst, 2016, 141, 1185
DOI: 10.1039/C5AN02208H

Efficient release of COS/H2S via BODIPY-based photocaged thionocarbamates
Yanmei Li, Emily Kryvorutsky, Yuanwei Zhang and Pier Alexandre Champagne
J. Mater. Chem. B, 2025, 13, 11046
DOI: 10.1039/D5TB01313E

Recent advances in the delivery of hydrogen sulfide via a macromolecular approach
Matthew C. Urquhart, Francesca Ercole, Michael R. Whittaker, Ben J. Boyd, Thomas P. Davis and John F. Quinn
Polym. Chem., 2018, 9, 4431
DOI: 10.1039/C8PY00938D

Light responsive hydrogen selenide (H2Se)/hydrogen diselenide (H2Se2) donors: applied for protein S-selenylation on PRDX6
Biswajit Roy, Eshani Das, Meg Shieh, Seiryo Ogata, Minkyung Jung, Hiroaki Fujita, Sen Zhang, Jerome R. Robinson, Takaaki Akaike and Ming Xian
Chem. Sci., 2025, 16, 19178
DOI: 10.1039/D5SC05141J

Octahedral iodide Mo6 cluster complex bearing thiosulfate ligands: a dual chemotherapeutic and radiodynamic agent for advanced cancer therapy
Tatiana N. Pozmogova, Margarita V. Vegner, Yuri A. Vorotinkov, Sofia V. Korotkova, Mariya A. Gromova, Alphiya R. Tsygankova, Tatiana Ya. Guselnikova, Georgy D. Vavilov, Natalia V. Kuratieva, Dmitri V. Stass, Lidiya V. Shestopalova, Olga P. Khripko, Alexander M. Shestopalov and Michael A. Shestopalov
Biomater. Sci., 2025, 13, 6058
DOI: 10.1039/D5BM00909J

Supramolecular binding and release of sulfide and hydrosulfide anions in water
J. Vázquez and V. Sindelar
Chem. Commun., 2018, 54, 5859
DOI: 10.1039/C8CC00470F

“On demand” redox buffering by H2S contributes to antibiotic resistance revealed by a bacteria-specific H2S donor
Prashant Shukla, Vinayak S. Khodade, Mallojjala SharathChandra, Preeti Chauhan, Saurabh Mishra, Shivakumara Siddaramappa, Bulagonda Eswarappa Pradeep, Amit Singh and Harinath Chakrapani
Chem. Sci., 2017, 8, 4967
DOI: 10.1039/C7SC00873B

Controllable thioester-based hydrogen sulfide slow-releasing donors as cardioprotective agents
Hong Yao, Shanshan Luo, Junkai Liu, Shaowen Xie, Yanpeng Liu, Jinyi Xu, Zheying Zhu and Shengtao Xu
Chem. Commun., 2019, 55, 6193
DOI: 10.1039/C9CC02829C

Detection of aqueous and gaseous hydrogen sulfide with lanthanide–macrocycle binary complexes
Parvathy Mini, Samuel E. Walker, Michael R. Grace, Genevieve H. Dennison and Kellie L. Tuck
Dalton Trans., 2023, 52, 12235
DOI: 10.1039/D3DT02150E

Cysteine-activated hydrogen sulfide (H2S) delivery through caged carbonyl sulfide (COS) donor motifs
Yu Zhao, Andrea K. Steiger and Michael D. Pluth
Chem. Commun., 2018, 54, 4951
DOI: 10.1039/C8CC02428F

The biothiol-triggered organotrisulfide-based self-immolative fluorogenic donors of hydrogen sulfide enable lysosomal trafficking
Sulendar K. Mahato, Debojit Bhattacherjee and Krishna P. Bhabak
Chem. Commun., 2020, 56, 7769
DOI: 10.1039/D0CC00613K

Cysteine-responsive prodrug of the anti-cancer drug amonafide: fluorogenic adjuvant drug delivery with hydrogen sulfide (H2S)
Sulendar K. Mahato, Pallavi Barman, Md. Badirujjaman and Krishna P. Bhabak
Chem. Commun., 2023, 59, 4802
DOI: 10.1039/D3CC00220A

Light triggered uncaging of hydrogen sulfide (H2S) with real-time monitoring
Yarra Venkatesh, Joyjyoti Das, Amrita Chaudhuri, Anupam Karmakar, Tapas K. Maiti and N. D. Pradeep Singh
Chem. Commun., 2018, 54, 3106
DOI: 10.1039/C8CC01172A

Thioredoxin reductase-triggered fluorogenic donor of hydrogen sulfide: a model study with a symmetrical organopolysulfide probe with turn-on near-infrared fluorescent emission
Sulendar K. Mahato, Debojit Bhattacherjee, Pallavi Barman and Krishna P. Bhabak
J. Mater. Chem. B, 2022, 10, 2183
DOI: 10.1039/D1TB02425F

A two-photon responsive hydroxyphenylquinazolinone (HPQ)-based fluorescent organic nanoprodrug for H2S release against oxidative stress
Amrita Chaudhuri, Tara Singha, Bikash Chandra Jena, Maniklal Shee, Prasanta Kumar Datta, Mahitosh Mandal and N. D. Pradeep Singh
Chem. Commun., 2023, 59, 1177
DOI: 10.1039/D2CC05768A

Investigating the generation of hydrogen sulfide from the phosphonamidodithioate slow-release donor GYY4137
Benjamin E. Alexander, Simon J. Coles, Bridget C. Fox, Tahmina F. Khan, Joseph Maliszewski, Alexis Perry, Mateusz B. Pitak, Matthew Whiteman and Mark E. Wood
Med. Chem. Commun., 2015, 6, 1649
DOI: 10.1039/C5MD00170F

Thiobenzophenones: tunable hydrolysis-based donors for intracellular H2S delivery
Yan Jiao, Haishun Ye, Haojie Huang, Long Yi and Lu Sun
New J. Chem., 2022, 46, 7859
DOI: 10.1039/D2NJ01152B

A fluorescent turn-on H2S-responsive probe: design, synthesis and application
Yufeng Zhang, Haiyan Chen, Dan Chen, Di Wu, Xiaoqiang Chen, Sheng Hua Liu and Jun Yin
Org. Biomol. Chem., 2015, 13, 9760
DOI: 10.1039/C5OB01305D

Porous materials as carriers of gasotransmitters towards gas biology and therapeutic applications
Arnau Carné-Sánchez, Francisco J. Carmona, Chiwon Kim and Shuhei Furukawa
Chem. Commun., 2020, 56, 9750
DOI: 10.1039/D0CC03740K

Optical analysis of biological hydrogen sulphide: an overview of recent advancements
Bin Xiong, Lan Peng, Xuan Cao, Yan He and Edward S. Yeung
Analyst, 2015, 140, 1763
DOI: 10.1039/C4AN02204A

Biological phosphorylated molecules participate in the biomimetic and biological synthesis of cadmium sulphide quantum dots by promoting H2S release from cellular thiols
F. A. Venegas, L. A. Saona, J. P. Monrás, N. Órdenes-Aenishanslins, M. F. Giordana, G. Ulloa, B. Collao, D. Bravo and J. M. Pérez-Donoso
RSC Adv., 2017, 7, 40270
DOI: 10.1039/C7RA03578K

NIR light controlled release of caged hydrogen sulfide based on upconversion nanoparticles
Wansong Chen, Min Chen, Qiguang Zang, Liqiang Wang, Feiying Tang, Yajing Han, Cejun Yang, Liu Deng and You-Nian Liu
Chem. Commun., 2015, 51, 9193
DOI: 10.1039/C5CC02508G

Visible light-driven photogeneration of hydrogen sulfide
Seung Yeon Yi, Yu Kyung Moon, Sinheui Kim, Sonam Kim, Gyurim Park, Jin Ju Kim and Youngmin You
Chem. Commun., 2017, 53, 11830
DOI: 10.1039/C7CC06990A

An injectable hydrogel dressing for controlled release of hydrogen sulfide pleiotropically mediates the wound microenvironment
Junwei Yang, Xianzhen Dong, Wenying Wei, Kun Liu, Xiaopei Wu and Honglian Dai
J. Mater. Chem. B, 2024, 12, 5377
DOI: 10.1039/D4TB00411F

Reactive oxygen species-triggered off-on fluorescence donor for imaging hydrogen sulfide delivery in living cells
Yiming Hu, Xiaoyi Li, Yu Fang, Wen Shi, Xiaohua Li, Wei Chen, Ming Xian and Huimin Ma
Chem. Sci., 2019, 10, 7690
DOI: 10.1039/C9SC02323B

Fluorescent small molecule donors
Guang Chen, Jing Yu, Luling Wu, Xinrui Ji, Jie Xu, Chao Wang, Siyue Ma, Qing Miao, Linlin Wang, Chen Wang, Simon E. Lewis, Yanfeng Yue, Zhe Sun, Yuxia Liu, Bo Tang and Tony D. James
Chem. Soc. Rev., 2024, 53, 6345
DOI: 10.1039/D3CS00124E

Enhanced NO-induced angiogenesisviaNO/H2S co-delivery from self-assembled nanoparticles
Jieun Lee, Chungmo Yang, Sangeun Ahn, Yeonjeong Choi and Kangwon Lee
Biomater. Sci., 2021, 9, 5150
DOI: 10.1039/D1BM00448D

A mitochondria-targeted nitric oxide donor triggered by superoxide radical to alleviate myocardial ischemia/reperfusion injury
Jingli Hou, Haiyan He, Saipeng Huang, Meng Qian, Jie Wang, Xiaoli Tan, Guifang Han, Yuguang Song, Zhelong Xu and Yangping Liu
Chem. Commun., 2019, 55, 1205
DOI: 10.1039/C8CC07304J

A practical guide to working with H2S at the interface of chemistry and biology
Matthew D. Hartle and Michael D. Pluth
Chem. Soc. Rev., 2016, 45, 6108
DOI: 10.1039/C6CS00212A

NBu4SH provides a convenient source of HS− soluble in organic solution for H2S and anion-binding research
Matthew D. Hartle, Daniel J. Meininger, Lev N. Zakharov, Zachary J. Tonzetich and Michael D. Pluth
Dalton Trans., 2015, 44, 19782
DOI: 10.1039/C5DT03355A

Dithioesters: simple, tunable, cysteine-selective H2S donors
Matthew M. Cerda, Turner D. Newton, Yu Zhao, Brylee K. Collins, Christopher H. Hendon and Michael D. Pluth
Chem. Sci., 2019, 10, 1773
DOI: 10.1039/C8SC04683B

A hydrogen sulfide-releasing alginate dressing for effective wound healing
Xia Zhao, Lin Liu, Tiezhu An, Ming Xian, Jittima Amie Luckanagul, Zhaohui Su, Yuan Lin and Qian Wang
Acta Biomaterialia, 2020, 104, 85
DOI: 10.1016/j.actbio.2019.12.032

Pharmacology of Hydrogen Sulfide and Its Donors in Cardiometabolic Diseases
Hai-Jian Sun, Qing-Bo Lu, Xue-Xue Zhu, Zhang-Rong Ni, Jia-Bao Su, Xiao Fu, Guo Chen, Guan-Li Zheng, Xiao-Wei Nie and Jin-Song Bian
Pharmacological Reviews, 2024, 76, 846
DOI: 10.1124/pharmrev.123.000928

Inorganic Nanomaterials-Mediated Immune Regulation for Inflammation Resolution
Zhixin Chen, Han Lin and Jianlin Shi
Nano Biomedicine and Engineering, 2025, 17, 346
DOI: 10.26599/NBE.2025.9290131

Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor
Shi Xu, Chun-Tao Yang, Fu-Hui Meng, Armando Pacheco, Li Chen and Ming Xian
Bioorganic & Medicinal Chemistry Letters, 2016, 26, 1585
DOI: 10.1016/j.bmcl.2016.02.005

Supramolecular Nanostructures with Tunable Donor Loading for Controlled H2S Release
Yin Wang and John B. Matson
ACS Appl. Bio Mater., 2019, 2, 5093
DOI: 10.1021/acsabm.9b00768

Methods for Suppressing Hydrogen Sulfide in Biological Systems
Yingying Wang, Xiang Ni, Rahuljeet Chadha, Caitlin McCartney, Yannie Lam, Brock Brummett, Geat Ramush and Ming Xian
Antioxidants & Redox Signaling, 2022, 36, 294
DOI: 10.1089/ars.2021.0088

Development and application of LC-MS/MS method for the quantification of hydrogen sulfide in the eye
Anthonia Okolie, Maria Rincon Nigro, Sharhazad Polk, Keyona Stubbs, Selvam Chelliah, Sunny E. Ohia, Dong Liang and Ya Fatou Njie Mbye
Analytical Biochemistry, 2024, 687, 115448
DOI: 10.1016/j.ab.2023.115448

Sequential Release of Ibuprofen and the Gasotransmitter Hydrogen sulfide using Oxanorbornane‐Based Synthetic Lipids as Carriers
Akshaya Kana Veedu, Archana Panthalattu Parambil and Muraleedharan K. Manheri
ChemPlusChem, 2024, 89
DOI: 10.1002/cplu.202400323

Design, Synthesis, Biological Evaluation and Molecular Docking Studies of Quercetin‐Linker‐H2S Donor Conjugates for the Treatment of Diabetes and Wound Healing**
Shibo He, Jian Liu, Lifei Hu, Yifeng Zhan, Hang Tong, Hongda Zhu, Huiling Guo, Hongmei Sun and Mingxing Liu
Chemistry & Biodiversity, 2023, 20
DOI: 10.1002/cbdv.202300513

Development of multifunctional H2S-releasing gold nanoparticles for chronic wound treatment
Van Phong Nguyen, Huyen Thanh Anh Nguyen, Ngoc Thuy Trang Le, Ngoc Hoi Nguyen, Dai Hai Nguyen and Dieu Linh Tran
Adv. Nat. Sci: Nanosci. Nanotechnol., 2024, 15, 045006
DOI: 10.1088/2043-6262/ad7c23

Hydrogen Sulfide in Analgesia: The Journey from Gas to Hybrids and Beyond
Hong-Qing Feng, Xiao-Min Han, Hao-Yun Chen, Wen-Jing Gao and Tao Zhuang
J. Med. Chem., 2026, 69, 7512
DOI: 10.1021/acs.jmedchem.5c03235

Hydrogen sulfide attenuates diabetic neuropathic pain through NO/cGMP/PKG pathway and μ-opioid receptor
Hao Li, Shulin Liu, Zheng Wang, Yonglai Zhang and Kaiguo Wang
Exp Biol Med (Maywood), 2020, 245, 823
DOI: 10.1177/1535370220918193

Controllable Cycloadditions between 2H-(Thio)pyran-2-(thi)ones and Strained Alkynes: A Click-and-Release Strategy for COS/H2S Generation
Qi Cui, Tony W. Pan, Meg Shieh, Shane S. Kelly, Shi Xu, Wei-Jun Qian and Ming Xian
Org. Lett., 2022, 24, 7334
DOI: 10.1021/acs.orglett.2c02819

Hydrogen Sulfide Affects the Root Development of Strawberry During Plug Transplant Production
Jiangtao Hu, Yali Li, Ya Liu, Dong Il Kang, Hao Wei and Byoung Ryong Jeong
Agriculture, 2020, 10, 12
DOI: 10.3390/agriculture10010012

H2S Generation from CS2 Hydrolysis at a Dinuclear Zinc(II) Site
Ananya Saju, Aditesh Mondal, Taraknath Chattopadhyay, Gayathri Kolliyedath and Subrata Kundu
Inorg. Chem., 2020, 59, 16154
DOI: 10.1021/acs.inorgchem.0c01194

A Theranostic Probe for Promotion of Skin Wound Healing by Exudate-Triggered H2S Release with Self-Monitoring Ability
Chao Lu, Youzhen Li, Wenchao Zhu, Yan Yang, Kai Liu, Qingtao Li and Meng Gao
ACS Appl. Bio Mater., 2023, 6, 674
DOI: 10.1021/acsabm.2c00919

The Janus Face of Oxidative Stress and Hydrogen Sulfide: Insights into Neurodegenerative Disease Pathogenesis
Constantin Munteanu, Anca Irina Galaction, Gelu Onose, Marius Turnea and Mariana Rotariu
Antioxidants, 2025, 14, 360
DOI: 10.3390/antiox14030360

Diallyl trisulfide protects against ethanol-induced oxidative stress and apoptosis via a hydrogen sulfide-mediated mechanism
Lian-Yun Chen, Qin Chen, Xiao-Jing Zhu, De-Song Kong, Li Wu, Jiang-juan Shao and Shi-Zhong Zheng
International Immunopharmacology, 2016, 36, 23
DOI: 10.1016/j.intimp.2016.04.015

Exogenous hydrogen sulfide inhibits oral mucosal wound‐induced macrophage activation via the NF‐κB pathway
R Zhuang, L Guo, J Du, S Wang, J Li and Y Liu
Oral Diseases, 2018, 24, 793
DOI: 10.1111/odi.12838

Real-time and in situ enzyme inhibition assay for the flux of hydrogen sulfide based on 3D interwoven AuPd-reduced graphene oxide network
Hongmei Yang, Yan Zhang, Li Li, Guoqiang Sun, Lina Zhang, Shenguang Ge and Jinghua Yu
Biosensors and Bioelectronics, 2017, 87, 53
DOI: 10.1016/j.bios.2016.08.009

A Fast-Response Red Shifted Fluorescent Probe for Detection of H2S in Living Cells
Ismail Ismail, Zhuoyue Chen, Xiuru Ji, Lu Sun, Long Yi and Zhen Xi
Molecules, 2020, 25, 437
DOI: 10.3390/molecules25030437

Kinetic Insights into Hydrogen Sulfide Delivery from Caged-Carbonyl Sulfide Isomeric Donor Platforms
Yu Zhao, Hillary A. Henthorn and Michael D. Pluth
J. Am. Chem. Soc., 2017, 139, 16365
DOI: 10.1021/jacs.7b09527

Inorganic polysulfides: Quantum chemistry study and biological implications
Wei-Hao Song and Ching-Han Hu
Chemical Physics Letters, 2020, 761, 138069
DOI: 10.1016/j.cplett.2020.138069

Something smells bad to plant pathogens: Production of hydrogen sulfide in plants and its role in plant defence responses
Daniel Vojtovič, Lenka Luhová and Marek Petřivalský
Journal of Advanced Research, 2021, 27, 199
DOI: 10.1016/j.jare.2020.09.005

Investigation of a bimetallic terbium(III)/copper(II) chemosensor for the detection of aqueous hydrogen sulfide
Parvathy Mini, Michael R Grace, Genevieve H Dennison and Kellie L Tuck
Beilstein J. Org. Chem., 2024, 20, 2818
DOI: 10.3762/bjoc.20.237

Prodrugs of hydrogen sulfide and related sulfur species: recent development
Zheng-Nan YUAN, Yue-Qin ZHENG and Bing-He WANG
Chinese Journal of Natural Medicines, 2020, 18, 296
DOI: 10.1016/S1875-5364(20)30037-6

BODIPY-based naked-eye fluorescent on-off probe with high selectivity for H2S based on thiolysis of dinitrophenyl ether
Tao Fang, Xin-Dong Jiang, Changliang Sun and Qian Li
Sensors and Actuators B: Chemical, 2019, 290, 551
DOI: 10.1016/j.snb.2019.03.141

On-demand therapeutic delivery of hydrogen sulfide aided by biomolecules
Yuxuan Ge, Fan Rong, Wei Li and Yin Wang
Journal of Controlled Release, 2022, 352, 586
DOI: 10.1016/j.jconrel.2022.10.055

Acyl Selenyl Sulfides as the Precursors for Reactive Sulfur Species (Hydrogen Sulfide, Polysulfide, and Selenyl Sulfide)
Akil Hamsath, Yingying Wang, Chun-tao Yang, Shi Xu, Danica Cañedo, Wei Chen and Ming Xian
Org. Lett., 2019, 21, 5685
DOI: 10.1021/acs.orglett.9b02021

An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment
Xianzhen Dong, Hao Zhang, Ping Duan, Kun Liu, Yifeng Yu, Wenying Wei, Weixing Wang, Yuhang Liu, Qiang Cheng, Xinyue Liang, Yuanfang Huo, Lesan Yan, Aixi Yu and Honglian Dai
Sci. Adv., 2023, 9
DOI: 10.1126/sciadv.adi1078

Sodium thiosulfate attenuates liver injury in a rat model of sepsis by modulating ferroptosis and oxidative stress
Andrei Otto Mitre, Ioana Baldea, Gabriela Adriana Filip, Raluca Maria Pop, Maria Adriana Neag, Bianca Mitre, Andrada Negoescu, Adrian Tibor Press and Alina Elena Parvu
Sci Rep, 2025, 16
DOI: 10.1038/s41598-025-29462-9

Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body
Nathalie Hock, Giuseppe Francesco Racaniello, Sam Aspinall, Nunzio Denora, Vitaliy V. Khutoryanskiy and Andreas Bernkop‐Schnürch
Advanced Science, 2022, 9
DOI: 10.1002/advs.202102451

Discovery of New H2S Releasing Phosphordithioates and 2,3-Dihydro-2-phenyl-2-sulfanylenebenzo[d][1,3,2]oxazaphospholes with Improved Antiproliferative Activity
Wei Feng, Xin-Yi Teo, Wisna Novera, Pondy Murugappan Ramanujulu, Dong Liang, Dejian Huang, Philip K. Moore, Lih-Wen Deng and Brian W. Dymock
J. Med. Chem., 2015, 58, 6456
DOI: 10.1021/acs.jmedchem.5b00848

A novel carbazole-based hydrogen-sulfide donor suppresses seizures and upregulates ATP-sensitive potassium channels
Xiaoqin Zhu, Yan He, Zhongrui Liu, Ziting Zhu, Yuehua He, Jiewen Qiu, Danqiong Liu, Mingshu Mo, Peng Wang, Xiumei Tian and Pingyi Xu
Applied Materials Today, 2020, 19, 100559
DOI: 10.1016/j.apmt.2020.100559

Role of hydrogen sulfide in ventilatory responses to hypercapnia in the medullary raphe of adult rats
João Paulo Jacob Sabino, Lucas Vaz de Castro Oliveira, Renato Nery Soriano, Marcelo Kwiatkoski, Luiz G. S. Branco and Glauber S. F. da Silva
Experimental Physiology, 2021, 106, 1992
DOI: 10.1113/EP089335

pH-responsive Oral liposomal delivery of hydrogen sulfide donor GYY4137 enables colon-targeted therapy for inflammatory bowel disease
Chiwoo Oh, Jee-Eun Hwang, Hyunjoon Yim, Haena Park, Seo-young Kim, Jae Kyoo Lee and Hyung-Jun Im
J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03753-9

Light-Activated COS/H2S Donation from Photocaged Thiocarbamates
Yu Zhao, Sarah G. Bolton and Michael D. Pluth
Org. Lett., 2017, 19, 2278
DOI: 10.1021/acs.orglett.7b00808

Self-Assembled Nanostructures Regulate H2S Release from Constitutionally Isomeric Peptides
Yin Wang, Kuljeet Kaur, Samantha J. Scannelli, Ronit Bitton and John B. Matson
J. Am. Chem. Soc., 2018, 140, 14945
DOI: 10.1021/jacs.8b09320

Applications of Synthetic Organic Tetrasulfides as H2S Donors
Matthew M. Cerda, Matthew D. Hammers, Mary S. Earp, Lev N. Zakharov and Michael D. Pluth
Org. Lett., 2017, 19, 2314
DOI: 10.1021/acs.orglett.7b00858

Interaction of exogenous hydrogen sulphide and ethylene on senescence of green leafy vegetables
H.M.S. Al Ubeed, R.B.H. Wills, M.C. Bowyer, Q.V. Vuong and J.B. Golding
Postharvest Biology and Technology, 2017, 133, 81
DOI: 10.1016/j.postharvbio.2017.07.010

Sodium thiosulfate refuels the hepatic antioxidant pool reducing ischemia-reperfusion-induced liver injury
Adrian T. Press, Luisa Ungelenk, Anna Medyukhina, Samantha A. Pennington, Sandor Nietzsche, Chunyi Kan, Amelie Lupp, Uta Dahmen, Rui Wang, Utz Settmacher, Reinhard Wetzker, Marc Thilo Figge, Mark G. Clemens and Michael Bauer
Free Radical Biology and Medicine, 2023, 204, 151
DOI: 10.1016/j.freeradbiomed.2023.04.012

Triggered and Tunable Hydrogen Sulfide Release from Photogenerated Thiobenzaldehydes
Zeyun Xiao, Thomas Bonnard, Aida Shakouri‐Motlagh, Ross A. L. Wylie, Joe Collins, Jonathan White, Daniel E. Heath, Christoph E. Hagemeyer and Luke A. Connal
Chemistry A European J, 2017, 23, 11294
DOI: 10.1002/chem.201701206

Development of a shape‐controlled H2S delivery system using epoxide‐functional nanoparticles
Sul Hwa Yu, Lars Esser, Song Yang Khor, Danielle Senyschyn, Nicholas A. Veldhuis, Michael R. Whittaker, Francesca Ercole, Thomas P. Davis and John F. Quinn
J. Polym. Sci. Part A: Polym. Chem., 2019, 57, 1982
DOI: 10.1002/pola.29382

H2S donor molecules against cold ischemia-reperfusion injury in preclinical models of solid organ transplantation
George J. Dugbartey, Smriti Juriasingani, Max Y. Zhang and Alp Sener
Pharmacological Research, 2021, 172, 105842
DOI: 10.1016/j.phrs.2021.105842

The Path to Controlled Delivery of Reactive Sulfur Species
Xiang Ni, Shane S. Kelly, Shi Xu and Ming Xian
Acc. Chem. Res., 2021, 54, 3968
DOI: 10.1021/acs.accounts.1c00506

Hyperpolarized 129Xe Magnetic Resonance Imaging Sensor for H2S
Shengjun Yang, Yaping Yuan, Weiping Jiang, Lili Ren, He Deng, Louis S. Bouchard, Xin Zhou and Maili Liu
Chemistry A European J, 2017, 23, 7648
DOI: 10.1002/chem.201605768

Peptide Nanostructure-Mediated Antibiotic Delivery by Exploiting H2S-Rich Environment in Clinically Relevant Bacterial Cultures
Narendra Singh, Ramesh Singh, Manjulika Shukla, Grace Kaul, Sidharth Chopra, Khashti Ballabh Joshi and Sandeep Verma
ACS Infect. Dis., 2020, 6, 2441
DOI: 10.1021/acsinfecdis.0c00227

Characterization of H2S releasing properties of various H2S donors utilizing microplate cover-based colorimetric assay
Tae Jun Kim, Young Ju Lee, Yong Jin Ahn and Gi-Ja Lee
Analytical Biochemistry, 2019, 574, 57
DOI: 10.1016/j.ab.2019.03.021

Esterase‐Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide
Yueqin Zheng, Bingchen Yu, Kaili Ji, Zhixiang Pan, Vayou Chittavong and Binghe Wang
Angewandte Chemie, 2016, 128, 4590
DOI: 10.1002/ange.201511244

Identifying the Role of Intramolecular Charge Transfer and Excited-State Proton Transfer in Fluorescence Mechanism for an Azido-Based Chemosensor
Ningjiu Zhao, Yang Li, Yan Jia and Peng Li
J. Phys. Chem. C, 2018, 122, 26576
DOI: 10.1021/acs.jpcc.8b06185

Cysteine-Activated Small-Molecule H2Se Donors Inspired by Synthetic H2S Donors
Xueying Kang, Haojie Huang, Chenyang Jiang, Longhuai Cheng, Yueqian Sang, Xuekang Cai, Yalun Dong, Lu Sun, Xin Wen, Zhen Xi and Long Yi
J. Am. Chem. Soc., 2022, 144, 3957
DOI: 10.1021/jacs.1c12006

Nanomedicine‐Enabled Chemical Regulation of Reactive X Species for Versatile Disease Treatments
Xinyue Dai, Yujie Xie, Wei Feng and Yu Chen
Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202309160

A multifunctional probe that responds sequentially to hydrogen sulfide and hypochlorous acid
Feng Li, Bang-Zhao Zhou, Shou-Kang Sun, Jun-Ying Miao, Bao-Xiang Zhao and Zhao-Min Lin
Microchemical Journal, 2024, 207, 111945
DOI: 10.1016/j.microc.2024.111945

Hydrogen sulphide donors selectively potentiate a green tea polyphenol EGCG-induced apoptosis of multiple myeloma cells
Jaehoon Bae, Motofumi Kumazoe, Shuya Yamashita and Hirofumi Tachibana
Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-06879-5

The Rhodanese PspE Converts Thiosulfate to Cellular Sulfane Sulfur in Escherichia coli
Qiaoli Yu, Mingxue Ran, Yuping Xin, Huaiwei Liu, Honglei Liu, Yongzhen Xia and Luying Xun
Antioxidants, 2023, 12, 1127
DOI: 10.3390/antiox12051127

Engineering Gas‐Releasing Nanomaterials for Efficient Wound Healing
Yutian Duan, Lei Li, Jinming Hu, Bin Zheng and Kewu He
ChemBioChem, 2025, 26
DOI: 10.1002/cbic.202400790

Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
Jan Lj. Miljkovic, Nils Burger, Justyna M. Gawel, John F. Mulvey, Abigail A.I. Norman, Takanori Nishimura, Yoshiyuki Tsujihata, Angela Logan, Olga Sauchanka, Stuart T. Caldwell, Jordan L. Morris, Tracy A. Prime, Stefan Warrington, Julien Prudent, Georgina R. Bates, Dunja Aksentijević, Hiran A. Prag, Andrew M. James, Thomas Krieg, Richard C. Hartley and Michael P. Murphy
Redox Biology, 2022, 55, 102429
DOI: 10.1016/j.redox.2022.102429

Endogenous hydrogen sulfide (H2S) is up-regulated during sweet pepper (Capsicum annuum L.) fruit ripening. In vitro analysis shows that NADP-dependent isocitrate dehydrogenase (ICDH) activity is inhibited by H2S and NO
María A. Muñoz-Vargas, Salvador González-Gordo, Amanda Cañas, Javier López-Jaramillo, José M. Palma and Francisco J. Corpas
Nitric Oxide, 2018, 81, 36
DOI: 10.1016/j.niox.2018.10.002

Colorimetric Carbonyl Sulfide (COS)/Hydrogen Sulfide (H2S) Donation from γ‐Ketothiocarbamate Donor Motifs
Yu Zhao, Andrea K. Steiger and Michael D. Pluth
Angew Chem Int Ed, 2018, 57, 13101
DOI: 10.1002/anie.201806854

A copper-based metal-organic framework for ratiometric detection of hydrogen sulfide with high sensitivity and fast response
Xiaoli Zhao, Lijiao Zhang, Jianguo Bai, Pengyan Wu, Yang Li, Lili Liang, Liheng Xie and Jian Wang
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 243, 118794
DOI: 10.1016/j.saa.2020.118794

Direct Electrochemical Sensing of Hydrogen Sulfide without Sulfur Poisoning
Jackson R. Hall and Mark H. Schoenfisch
Anal. Chem., 2018, 90, 5194
DOI: 10.1021/acs.analchem.7b05421

RhB/UiO-66-N3 MOF-based ratiometric fluorescent detection and intracellular imaging of hydrogen sulfide
Xia Gao, Guangming Sun, Xinke Wang, Xiaodong Lin, Shuo Wang and Yaqing Liu
Sensors and Actuators B: Chemical, 2021, 331, 129448
DOI: 10.1016/j.snb.2021.129448

Hydrogen sulfide ameliorates high glucose-induced pro-inflammation factors in HT-22 cells: Involvement of SIRT1-mTOR/NF-κB signaling pathway
Xinrui Li, Peiquan Yu, Yinghua Yu, Ting Xu, Jiao Liu, Yuan Cheng, Xia Yang, Xiaoying Cui, Cui Yin and Yi Liu
International Immunopharmacology, 2021, 95, 107545
DOI: 10.1016/j.intimp.2021.107545

H2S-Releasing Composite: a Gasotransmitter Platform for Potential Biomedical Applications
Jitendra Pant, Arnab Mondal, James Manuel, Priyadarshini Singha, Juhi Mancha and Hitesh Handa
ACS Biomater. Sci. Eng., 2020, 6, 2062
DOI: 10.1021/acsbiomaterials.0c00146

Sorption Enhanced Water Gas Shift for H2 production using sour gases as feedstock
Andrea Bassani, H.A.J. van Dijk, P.D. Cobden, Giorgia Spigno, Giampaolo Manzolini and Flavio Manenti
International Journal of Hydrogen Energy, 2019, 44, 16132
DOI: 10.1016/j.ijhydene.2019.04.199

Reactive oxygen species activatable nanotherapeutics for evaluating and relieving nanoplastics-induced oxidative stress
Lili Fu, Yan Huang, Xiao Sun, Xinlei Wang, Shuang Li, Xiaoyan Wang, Qi Kang, Dazhong Shen and Lingxin Chen
Chemical Engineering Journal, 2025, 524, 169081
DOI: 10.1016/j.cej.2025.169081

8e Protects against Acute Cerebral Ischemia by Inhibition of PI3Kγ-Mediated Superoxide Generation in Microglia
Linna Wang, Xiaoli Wang, Tingting Li, Yihua Zhang and Hui Ji
Molecules, 2018, 23, 2828
DOI: 10.3390/molecules23112828

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar and Jingwei Xie
Advanced Science, 2026
DOI: 10.1002/advs.202521942

Rational design of a fluorescent probe and its applications of imaging and distinguishing between exogenous and endogenous H2S in living cells
Hanchuang Zhu, Wenlong Sheng, Caiyun Liu, Hanming Zhang, Changxu Liang, Xue Zhang, Kun Wang, Xiwei Li, Yamin Yu, Dawei Fan and Baocun Zhu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 266, 120407
DOI: 10.1016/j.saa.2021.120407

Thionoesters: A Native Chemical Ligation-Inspired Approach to Cysteine-Triggered H2S Donors
Matthew M. Cerda, Yu Zhao and Michael D. Pluth
J. Am. Chem. Soc., 2018, 140, 12574
DOI: 10.1021/jacs.8b07268

Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux
Xia Wang, Xiying Huang, Yongya Zhang, Huanhuan Huo, Guo Zhou, Linghong Shen, Long Li and Ben He
Redox Biology, 2025, 79, 103456
DOI: 10.1016/j.redox.2024.103456

“Green” gas-generation strategy to combine cancer phototherapy for remarkably enhanced efficacy
Jiahui Wu, Gege Zhang, Mi Zou, Qiong Huang, Yanling Zhang, Yajie Sui, Shuang Wu, Jianming Yang, Qiaojun Fang and Pingping Liang
Nano TransMed, 2025, 4, 100090
DOI: 10.1016/j.ntm.2025.100090

Activatable Small-Molecule Hydrogen Sulfide Donors
Carolyn M. Levinn, Matthew M. Cerda and Michael D. Pluth
Antioxidants & Redox Signaling, 2020, 32, 96
DOI: 10.1089/ars.2019.7841

Hydrogen sulfide: Roles in plant abiotic stress response and crosstalk with other signals
Dengjing Huang, Jianqiang Huo and Weibiao Liao
Plant Science, 2021, 302, 110733
DOI: 10.1016/j.plantsci.2020.110733

4-Methylbenzenecarbothioamide, a hydrogen sulfide donor, inhibits tumor necrosis factor-α and CXCL1 production and exhibits activity in models of pain and inflammation
Ivo S.F. Melo, Felipe F. Rodrigues, Sarah O.A.M. Costa, Alysson Vinícius Braga, Marcela Ísis Morais, Jéssica A. Vaz, Leonardo S. Neto, Izabela Galvão, Luzia V. Modolo, Flávio A. Amaral, Renata B. Oliveira, Ângelo de Fátima, Márcio M. Coelho and Renes R. Machado
European Journal of Pharmacology, 2019, 856, 172404
DOI: 10.1016/j.ejphar.2019.172404

Production of keratin hydrolysates from irradiated chicken feathers via chemical and enzymatic treatments
Marco Vinicio Sinche-Serra, Gabriela Elizabeth Mendieta Orellana, Samantha Rafaela Cevallos Coronel, Edwin Rafael Vera-Calle, Paul Ernesto Vargas-Jentzsch and Juan Patricio Castillo-Domínguez
CyTA - Journal of Food, 2025, 23
DOI: 10.1080/19476337.2025.2547835

Hydrogen sulfide causes excision of a genomic island in Pseudomonas syringae pv. phaseolicola
H. Neale, N. Deshappriya, D. Arnold, M. E. Wood, M. Whiteman and J. T. Hancock
Eur J Plant Pathol, 2017, 149, 911
DOI: 10.1007/s10658-017-1240-7

Mechanistic Intimate Insights into the Role of Hydrogen Sulfide in Alzheimer’s Disease: A Recent Systematic Review
Constantin Munteanu, Daniel Andrei Iordan, Mihail Hoteteu, Cristina Popescu, Ruxandra Postoiu, Ilie Onu and Gelu Onose
IJMS, 2023, 24, 15481
DOI: 10.3390/ijms242015481

A Visible Colorimetric Fluorescent Probe for Hydrogen Sulfide Detection in Wine
Haitao Chen, Xiaoming Wu, Shaoxiang Yang, Hongyu Tian, Yongguo Liu and Baoguo Sun
Journal of Analytical Methods in Chemistry, 2019, 2019, 1
DOI: 10.1155/2019/2173671

Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters
Ma Su, Xingyue Ji, Feng Liu, Zhang Li and Duanyang Yan
MRMC, 2024, 24, 300
DOI: 10.2174/1389557523666230427152234

It's a Gas: Bioconjugation With Vapor‐Phase Reagents
Yuxuan Ding, Jun Ohata and Zachary T. Ball
Chemistry A European J, 2026
DOI: 10.1002/chem.202503565

Hydrogen sulfide prodrugs—a review
Yueqin Zheng, Xingyue Ji, Kaili Ji and Binghe Wang
Acta Pharmaceutica Sinica B, 2015, 5, 367
DOI: 10.1016/j.apsb.2015.06.004

Effects of natural and synthetic isothiocyanate-based H 2 S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels
Lorenzo Di Cesare Mannelli, Elena Lucarini, Laura Micheli, Ilaria Mosca, Paolo Ambrosino, Maria Virginia Soldovieri, Alma Martelli, Lara Testai, Maurizio Taglialatela, Vincenzo Calderone and Carla Ghelardini
Neuropharmacology, 2017, 121, 49
DOI: 10.1016/j.neuropharm.2017.04.029

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53
Valentina Pagliara, Assunta Saide, Emma Mitidieri, Roberta d’Emmanuele di Villa Bianca, Raffaella Sorrentino, Giulia Russo and Annapina Russo
Oncotarget, 2016, 7, 50333
DOI: 10.18632/oncotarget.10385

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?
Esma Yagdi, Claudia Cerella, Mario Dicato and Marc Diederich
Food and Chemical Toxicology, 2016, 95, 219
DOI: 10.1016/j.fct.2016.07.016

Development of a Silicone-Based Polymer Matrix as a Suitable Transdermal Therapeutic System for Diallyl Disulfide
Szabolcs László, Zsófia Hajna, Attila Egyed, Erika Pintér and Ödön Wagner
Pharmaceuticals, 2022, 15, 1182
DOI: 10.3390/ph15101182

Strategies for the Design of Donors and Precursors of Reactive Sulfur Species
Shi Xu, Akil Hamsath, Deshka L. Neill, Yingying Wang, Chun‐tao Yang and Ming Xian
Chemistry A European J, 2019, 25, 4005
DOI: 10.1002/chem.201804895

Chemical Biology of H2S Signaling through Persulfidation
Milos R. Filipovic, Jasmina Zivanovic, Beatriz Alvarez and Ruma Banerjee
Chem. Rev., 2018, 118, 1253
DOI: 10.1021/acs.chemrev.7b00205

Chitosan Biocomposites for the Adsorption and Release of H2S
Mary Batista, Moisés L. Pinto, Fernando Antunes, João Pires and Silvia Carvalho
Materials, 2021, 14, 6701
DOI: 10.3390/ma14216701

Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis
Paola De Cicco, Theodore Sanders, Giuseppe Cirino, Kevin J. Maloy and Angela Ianaro
Front. Immunol., 2018, 9
DOI: 10.3389/fimmu.2018.00499

A hypothermia-sensitive micelle with controlled release of hydrogen sulfide for protection against anoxia/reoxygenation-induced cardiomyocyte injury
Lianlei Wen, Tao Yan, Yan Xiao, Wenyi Xia, Xueyan Li, Changfa Guo and Meidong Lang
European Polymer Journal, 2022, 175, 111325
DOI: 10.1016/j.eurpolymj.2022.111325

Esterase‐Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide
Yueqin Zheng, Bingchen Yu, Kaili Ji, Zhixiang Pan, Vayou Chittavong and Binghe Wang
Angew Chem Int Ed, 2016, 55, 4514
DOI: 10.1002/anie.201511244

Hydrogen sulfide in placental development and pregnancy disorders: mechanisms, therapeutic potential, and translational challenges
Lijia Du, Rui Zheng, Weina Ren, Yingru Liu, Xiaoxiong Zhu, Shiyang Chang and Zhifen Yang
Reprod Biol Endocrinol, 2025, 23
DOI: 10.1186/s12958-025-01465-1

Thiol-Activated gem-Dithiols: A New Class of Controllable Hydrogen Sulfide Donors
Yu Zhao, Jianming Kang, Chung-Min Park, Powell E. Bagdon, Bo Peng and Ming Xian
Org. Lett., 2014, 16, 4536
DOI: 10.1021/ol502088m

Hydrogen sulfide and its donors for the treatment of cerebral ischaemia-reperfusion injury: A comprehensive review
Yiwei Huang, Moussa Omorou, Meng Gao, Chenxi Mu, Weijing Xu and Hui Xu
Biomedicine & Pharmacotherapy, 2023, 161, 114506
DOI: 10.1016/j.biopha.2023.114506

O→S Relay Deprotection: A General Approach to Controllable Donors of Reactive Sulfur Species
Jianming Kang, Shi Xu, Miles N. Radford, Wenjia Zhang, Shane S. Kelly, Jacob J. Day and Ming Xian
Angewandte Chemie, 2018, 130, 5995
DOI: 10.1002/ange.201802845

Molecular strategies used by hibernators: Potential therapeutic directions for ischemia reperfusion injury and preservation of human donor organs
E. Soo, A. Welch, C. Marsh and DB. McKay
Transplantation Reviews, 2020, 34, 100512
DOI: 10.1016/j.trre.2019.100512

Effects of sulphur-containing mineral water intake on oxidative status and markers for inflammation in healthy subjects
Todorka D. Sokrateva, Bogdan H. Roussev, Milka A. Nashar, Yoana D. Kiselova-Kaneva, Galya M. Mihaylova, Miglena N. Todorova, Milena G. Pasheva, Oskan B. Tasinov, Neshe F. Nazifova-Tasinova, Deyana G. Vankova, Desislava P. Ivanova, Maria A. Radanova, Bistra Ts. Galunska, Tatyana I. Vlaykova and Diana G. Ivanova
Archives of Physiology and Biochemistry, 2021, 127, 327
DOI: 10.1080/13813455.2019.1638416

Inorganic, Synthetic, Natural, and Innovative Hybrid Hydrogen Sulfide Donors and Inhibitors of Its Biosynthesis in the Treatment of Central and Peripheral Nervous System Injuries: A Systematic Analytical Review
Stanislav Rodkin, Sergey Golovin, Stanislav Bachurin, Anton Lisovin, Inna Vasilieva, Anastasia Tolmacheva, Vasilii Chulkov and Mitkhat Gasanov
IJMS, 2025, 26, 11842
DOI: 10.3390/ijms262411842

Recent Development of Hydrogen Sulfide Releasing/Stimulating Reagents and Their Potential Applications in Cancer and Glycometabolic Disorders
Chun-tao Yang, Li Chen, Shi Xu, Jacob J. Day, Xiang Li and Ming Xian
Front. Pharmacol., 2017, 8
DOI: 10.3389/fphar.2017.00664

Development of Acid-Mediated H2S/COS Donors That Respond to a Specific pH Window
Annie K. Gilbert, Yu Zhao, Claire E. Otteson and Michael D. Pluth
J. Org. Chem., 2019, 84, 14469
DOI: 10.1021/acs.joc.9b01873

Convenient method for the synthesis of 5-(4-methoxyphenyl)-3 H -1,2-dithiole-3-thione (ADT-OMe) and 5-(4-hydroxyphenyl)-3 H -1,2-dithiol-3-thione (ADT-OH) using microwave irradiation
Dimitra Pournara, Georgios A. Heropoulos and Maria Koufaki
Tetrahedron Letters, 2017, 58, 2378
DOI: 10.1016/j.tetlet.2017.05.010

Trends in H2S-Donors Chemistry and Their Effects in Cardiovascular Diseases
Angela Corvino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Antonia Scognamiglio, Giuseppe Caliendo, Ferdinando Fiorino and Beatrice Severino
Antioxidants, 2021, 10, 429
DOI: 10.3390/antiox10030429

A simple benzothiazole-based turn-on fluorescent probe for detecting H2S in HeLa cells
Tian-Zhen Liu, Shuo Wang, Ke-Li Zhao, Jun-Ying Miao, Bao-Xiang Zhao and Zhao-Min Lin
Dyes and Pigments, 2023, 217, 111418
DOI: 10.1016/j.dyepig.2023.111418

A H2S‐Specific Ultrasensitive Fluorogenic Probe Reveals TMV‐Induced H2S Production to Limit Virus Replication
Zhili Pang, Haishun Ye, Dejun Ma, Xiaoqiang Tu, Long Yi and Zhen Xi
ChemBioChem, 2021, 22, 2292
DOI: 10.1002/cbic.202100138

Polythionoester Vesicle: An Efficient Polymeric Platform for Tuning H2S Release
Cuiqin Yang, Xuefeng Li and Qiang Yan
ACS Macro Lett., 2022, 11, 1230
DOI: 10.1021/acsmacrolett.2c00473

Novel therapeutic strategies for renal graft preservation and their potential impact on the future of clinical transplantation
Smriti Juriasingani, Masoud Akbari, Patrick Luke and Alp Sener
Current Opinion in Organ Transplantation, 2019, 24, 385
DOI: 10.1097/MOT.0000000000000660

Neuroprotective Actions of Hydrogen Sulfide-Releasing Compounds in Isolated Bovine Retinae
Leah Bush, Jenaye Robinson, Anthonia Okolie, Fatima Muili, Catherine A. Opere, Matthew Whiteman, Sunny E. Ohia and Ya Fatou Njie Mbye
Pharmaceuticals, 2024, 17, 1311
DOI: 10.3390/ph17101311

Analgesic effect of dimethyl trisulfide in mice is mediated by TRPA1 and sst 4 receptors
Gábor Pozsgai, Maja Payrits, Éva Sághy, Réka Sebestyén-Bátai, Elise Steen, Éva Szőke, Zoltán Sándor, Margit Solymár, András Garami, Péter Orvos, László Tálosi, Zsuzsanna Helyes and Erika Pintér
Nitric Oxide, 2017, 65, 10
DOI: 10.1016/j.niox.2017.01.012

Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease
Zhen Li, David J. Polhemus and David J. Lefer
Circulation Research, 2018, 123, 590
DOI: 10.1161/CIRCRESAHA.118.311134

Odours in Asphalt: Analysis of the Release of H2S from Bitumen by a Mass Spectrometric Residual Gas Analyser
Marcello Monteleone, Giuseppe Di Luca, Marcello Filomia, Alessio Fuoco, Alberto Figoli and Johannes Carolus Jansen
MPs, 2024, 7, 55
DOI: 10.3390/mps7040055

Hymecromone naphthoquinone ethers as probes for hydrogen sulfide detection
Daniel Słowiński, Małgorzata Świerczyńska, Aleksandra Grzelakowska, Marcin Szala, Jolanta Kolińska, Jarosław Romański and Radosław Podsiadły
Dyes and Pigments, 2021, 196, 109765
DOI: 10.1016/j.dyepig.2021.109765

A Novel H2S Donor Alleviates Neuroinflammation and Seizures by Inhibiting the C3‐C3aR Pathway
Yaru Yang, Xutao Wang, Tiantian Wang, Xiao Wang, Honghao Xu, Lian Liu, Shuisheng Lei and Xiao qin Zhu
J of Neuroscience Research, 2025, 103
DOI: 10.1002/jnr.70041

Computational Study of H2S Release in Reactions of Diallyl Polysulfides with Thiols
You-Ru Cai and Ching-Han Hu
J. Phys. Chem. B, 2017, 121, 6359
DOI: 10.1021/acs.jpcb.7b03683

S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases
Fei Liu, Lan Li, Longhui Yuan, Jingchao Yang, Xi Tang, Jingping Liu, Shuyun Liu, Younan Chen, Yanrong Lu, Jingqiu Cheng and Yujia Yuan
Journal of Advanced Research, 2026, 81, 915
DOI: 10.1016/j.jare.2025.06.038

2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels
Qi Cui, Meg Shieh, Tony W. Pan, Akiyuki Nishimura, Tetsuro Matsunaga, Shane S. Kelly, Shi Xu, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Xiaoyan Chen, Jerome R. Robinson, Wei-Jun Qian, Motohiro Nishida, Takaaki Akaike and Ming Xian
Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-46652-7

A possible mechanism of inhibition of U87MG and SH-SY5Y cancer cell proliferation by diallyl trisulfide and other aspects of its activity
Halina Jurkowska, Maria Wróbel, Marta Kaczor-Kamińska and Ewa Jasek-Gajda
Amino Acids, 2017, 49, 1855
DOI: 10.1007/s00726-017-2484-4

Effects of hydrogen sulphide, nitric oxide and ethylene on postharvest deterioration of pak choy
H.M.S. Al Ubeed, R.B.H. Wills, M.C. Bowyer, Q.V. Vuong and J.B. Golding
Acta Hortic., 2019, 115
DOI: 10.17660/ActaHortic.2019.1256.16

Role of Hydrogen Sulfide in Ischemia-Reperfusion Injury
Dongdong Wu, Jun Wang, Hui Li, Mengzhou Xue, Ailing Ji and Yanzhang Li
Oxidative Medicine and Cellular Longevity, 2015, 2015, 1
DOI: 10.1155/2015/186908

Hydrogen sulfide‐loaded microbubbles combined with ultrasound mediate thrombolysis and simultaneously mitigate ischemia‐reperfusion injury in a rat hindlimb model
Jiayuan Zhong, Yili Sun, Yuan Han, Xiaoqiang Chen, Hairui Li, Yusheng Ma, Yanxian Lai, Guoquan Wei, Xiang He, Mengsha Li, Wangjun Liao, Yulin Liao, Shiping Cao and Jianping Bin
Journal of Thrombosis and Haemostasis, 2021, 19, 738
DOI: 10.1111/jth.15110

ChemInform Abstract: Hydrogen Sulfide (H2S) Releasing Agents: Chemistry and Biological Applications
Yu Zhao, Tyler D. Biggs and Ming Xian
ChemInform, 2014, 45
DOI: 10.1002/chin.201445292

Polymersome Wound Dressing Spray Capable of Bacterial Inhibition and H2S Generation for Complete Diabetic Wound Healing
Danqing Liu, Yuyao Liao, Erik Jan Cornel, Mingchen Lv, Tong Wu, Xinyue Zhang, Liujie Fan, Min Sun, Yunqing Zhu, Zhen Fan and Jianzhong Du
Chem. Mater., 2021, 33, 7972
DOI: 10.1021/acs.chemmater.1c01872

Targeted H 2 S-Mediated Gas Therapy with pH-Sensitive Release Property for Myocardial Ischemia–Reperfusion Injury by Platelet Membrane
Lin Liu, Yucen Yao, Yang Liu, Bingrong Hong, Ziqing Li, Xuejun Chen, Yaofeng Zhang, Hongbo Fu, Degong Yang and Chunrong Yang
Biomater Res, 2024, 28
DOI: 10.34133/bmr.0061

Hydrogen Sulfide: A Potential Novel Therapy for the Treatment of Ischemia
Amanda R. Jensen, Natalie A. Drucker, Sina Khaneki, Michael J. Ferkowicz, Mervin C. Yoder, Eric R. DeLeon, Kenneth R. Olson and Troy A. Markel
Shock, 2017, 48, 511
DOI: 10.1097/SHK.0000000000000894

Reactive Oxygen Species-Triggered Tunable Hydrogen Sulfide Release
Preeti Chauhan, Swetha Jos and Harinath Chakrapani
Org. Lett., 2018, 20, 3766
DOI: 10.1021/acs.orglett.8b01356

Chemistry of Hydrogen Sulfide—Pathological and Physiological Functions in Mammalian Cells
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Celia Andrés Juan, Francisco J. Plou and Eduardo Pérez-Lebeña
Cells, 2023, 12, 2684
DOI: 10.3390/cells12232684

A tetraphenylimidazole-based fluorescent probe for the detection of hydrogen sulfide and its application in living cells
Biao Gu, Naxiu Mi, Youyu Zhang, Pen Yin, Haitao Li and Shouzhuo Yao
Analytica Chimica Acta, 2015, 879, 85
DOI: 10.1016/j.aca.2015.03.017

Sustained Release of Hydrogen Sulfide (H2S) from Poly(Lactic Acid) Functionalized 4-Hydroxythiobenzamide Microparticles to Protect Against Oxidative Damage
Anh-Vu Do, Rasheid Smith, Phillip Tobias, Daniel Carlsen, Erica Pham, Ned B. Bowden and Aliasger K. Salem
Ann Biomed Eng, 2019, 47, 1691
DOI: 10.1007/s10439-019-02270-9

Comparison of hydrogen sulphide with 1-methylcyclopropene (1-MCP) to inhibit senescence of the leafy vegetable, pak choy
H.M.S. Al Ubeed, R.B.H. Wills, M.C. Bowyer and J.B. Golding
Postharvest Biology and Technology, 2018, 137, 129
DOI: 10.1016/j.postharvbio.2017.11.020

Emerging Roles of Carbonyl Sulfide in Chemical Biology: Sulfide Transporter or Gasotransmitter?
Andrea K. Steiger, Yu Zhao and Michael D. Pluth
Antioxidants & Redox Signaling, 2018, 28, 1516
DOI: 10.1089/ars.2017.7119

Sulphurous Mineral Waters: New Applications for Health
Jose Manuel Carbajo, Francisco Maraver and Marisa Colone
Evidence-Based Complementary and Alternative Medicine, 2017, 2017
DOI: 10.1155/2017/8034084

Hydrogen sulfide-releasing silk fibroin scaffold for bone tissue engineering
Laura Gambari, Emanuela Amore, Rosasilvia Raggio, Walter Bonani, Marli Barone, Gina Lisignoli, Brunella Grigolo, Antonella Motta and Francesco Grassi
Materials Science and Engineering: C, 2019, 102, 471
DOI: 10.1016/j.msec.2019.04.039

Self-Immolative Thiocarbamates Provide Access to Triggered H2S Donors and Analyte Replacement Fluorescent Probes
Andrea K. Steiger, Sibile Pardue, Christopher G. Kevil and Michael D. Pluth
J. Am. Chem. Soc., 2016, 138, 7256
DOI: 10.1021/jacs.6b03780

A Nitro‐Functionalized Metal–Organic Framework as a Reaction‐Based Fluorescence Turn‐On Probe for Rapid and Selective H2S Detection
Sanjog S. Nagarkar, Aamod V. Desai and Sujit K. Ghosh
Chemistry A European J, 2015, 21, 9994
DOI: 10.1002/chem.201501043

Evaluation of thioamides, thiolactams and thioureas as hydrogen sulfide (H2S) donors for lowering blood pressure
Ewelina Zaorska, Tomasz Hutsch, Marta Gawryś-Kopczyńska, Ryszard Ostaszewski, Marcin Ufnal and Dominik Koszelewski
Bioorganic Chemistry, 2019, 88, 102941
DOI: 10.1016/j.bioorg.2019.102941

An efficient molecular luminophore based on tetraphenylethylene (TPE) enabling intracellular detection and therapeutic benefits of hydrogen sulfide in Alzheimer’s disease
Adukkadan N. Ramya, Manu M. Joseph, Varsha Karunakaran, Chekrain Valappil Shihas Ahammed, Animesh Samanta and Kaustabh K. Maiti
Sensors and Actuators B: Chemical, 2022, 355, 131118
DOI: 10.1016/j.snb.2021.131118

Synthesis and Hydrogen Sulfide Releasing Properties of Diaminodisulfides and Dialkoxydisulfides
James P. Grace and Ned B. Bowden
ACS Omega, 2021, 6, 17741
DOI: 10.1021/acsomega.1c02585

Functional N-Substituted N-Thiocarboxyanhydrides as Modular Tools for Constructing H2S Donor Conjugates
Chadwick R. Powell, Kuljeet Kaur, Kearsley M. Dillon, Mingjun Zhou, Mohammed Alaboalirat and John B. Matson
ACS Chem. Biol., 2019, 14, 1129
DOI: 10.1021/acschembio.9b00248

Identification and Characterization of Bacterial Alliinase: Resource and Substrate Stereospecificity
Yuanxiang Liu, Yaru Li, Yishu Peng, Luhua Feng, Wei Wang, Chongzhou Li, Ye Zhang, Ruimin Wang, Chunfang Li, Cuiqing Ma and Chunyu Yang
J. Agric. Food Chem., 2024, 72, 13228
DOI: 10.1021/acs.jafc.4c02404

O→S Relay Deprotection: A General Approach to Controllable Donors of Reactive Sulfur Species
Jianming Kang, Shi Xu, Miles N. Radford, Wenjia Zhang, Shane S. Kelly, Jacob J. Day and Ming Xian
Angew Chem Int Ed, 2018, 57, 5893
DOI: 10.1002/anie.201802845

Colorimetric Carbonyl Sulfide (COS)/Hydrogen Sulfide (H2S) Donation from γ‐Ketothiocarbamate Donor Motifs
Yu Zhao, Andrea K. Steiger and Michael D. Pluth
Angewandte Chemie, 2018, 130, 13285
DOI: 10.1002/ange.201806854

Gas‐Releasing Polymer Tubesomes: Boosting Gas Delivery of Nanovehicles via Membrane Stretching
Cuiqin Yang, Yulian Zhang, Miaomiao Xu, Jianfeng Li and Qiang Yan
Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202421405

Two-photon imaging of hydrogen polysulfides in living cells and hippocampal tissues
Jeewon Chung, Haidong Li, Chang Su Lim, Hwan Myung Kim and Juyoung Yoon
Sensors and Actuators B: Chemical, 2020, 322, 128564
DOI: 10.1016/j.snb.2020.128564

Cleaner energy planning, management and technologies: Perspectives of supply-demand side and end-of-pipe management
Sharifah Rafidah Wan Alwi, Jiří Jaromír Klemeš and Petar Sabev Varbanov
Journal of Cleaner Production, 2016, 136, 1
DOI: 10.1016/j.jclepro.2016.07.181

Effects of Hydrogen Sulfide Donor NaHS on Porcine Vascular Wall-Mesenchymal Stem Cells
Chiara Bernardini, Debora La Mantia, Salvatore Nesci, Roberta Salaroli, Cristina Algieri, Alessandra Pagliarani, Augusta Zannoni and Monica Forni
IJMS, 2020, 21, 5267
DOI: 10.3390/ijms21155267

Protective Mechanism of Hydrogen Sulfide against Chemotherapy-Induced Cardiotoxicity
Shuxu Du, Yaqian Huang, Hongfang Jin and Tianyou Wang
Front. Pharmacol., 2018, 9
DOI: 10.3389/fphar.2018.00032

Protein persulfidation: Rewiring the hydrogen sulfide signaling in cell stress response
Bo He, Zhe Zhang, Zhao Huang, Xirui Duan, Yu Wang, Jiangjun Cao, Lei Li, Kai He, Edouard C. Nice, Weifeng He, Wei Gao and Zhisen Shen
Biochemical Pharmacology, 2023, 209, 115444
DOI: 10.1016/j.bcp.2023.115444

Phototriggered Hydrogen Persulfide Donors via Hydrosulfide Radical Formation Enhancing the Reactive Sulfur Metabolome in Cells
Biswajit Roy, Meg Shieh, Tsuyoshi Takata, Minkyung Jung, Eshani Das, Shi Xu, Takaaki Akaike and Ming Xian
J. Am. Chem. Soc., 2024, 146, 30502
DOI: 10.1021/jacs.4c11540

Cyclic Sulfenyl Thiocarbamates Release Carbonyl Sulfide and Hydrogen Sulfide Independently in Thiol-Promoted Pathways
Yu Zhao, Andrea K. Steiger and Michael D. Pluth
J. Am. Chem. Soc., 2019, 141, 13610
DOI: 10.1021/jacs.9b06319

Cardioprotective Effects of Hydrogen Sulfide and Its Potential Therapeutic Implications in the Amelioration of Duchenne Muscular Dystrophy Cardiomyopathy
Agnieszka Łoboda and Józef Dulak
Cells, 2024, 13, 158
DOI: 10.3390/cells13020158

Hydrogen sulfide conversion: How to capture hydrogen and sulfur by photocatalysis
Meng Dan, Shan Yu, Yi Li, Shiqian Wei, Jianglai Xiang and Ying Zhou
Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 2020, 42, 100339
DOI: 10.1016/j.jphotochemrev.2019.100339

Javelin-like, quasi-spherical, dendrite-like and rod-like complex nanostructures of BaCO3 growth by chemical bath deposition technique
V. Carranza Téllez, L. Serrano de la Rosa, M. Chávez Portillo, M.A. Mora-Ramírez, H. Juárez Santiesteban, M. Pacio Castillo and O. Portillo Moreno
Optik, 2020, 221, 165316
DOI: 10.1016/j.ijleo.2020.165316

H2S Donors and Their Use in Medicinal Chemistry
Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Giuseppe Caliendo, Angela Corvino, Gianluca Esposito, Giovanna Esposito, Ferdinando Fiorino, Marco Migliaccio, Antonia Scognamiglio, Beatrice Severino, Rosa Sparaco and Francesco Frecentese
Biomolecules, 2021, 11, 1899
DOI: 10.3390/biom11121899

Polynorbornene-derived block copolymer micelles via ring‐opening metathesis polymerization with capacity of hydrogen sulfide generation
Trong-Nghia Le, Huang Ru, Cheng-Kang Lee and N. Vijayakameswara Rao
European Polymer Journal, 2022, 173, 111294
DOI: 10.1016/j.eurpolymj.2022.111294

Hydrogen Sulfide Signaling Axis as a Target for Prostate Cancer Therapeutics
Mingzhe Liu, Lingyun Wu, Sabine Montaut and Guangdong Yang
Prostate Cancer, 2016, 2016, 1
DOI: 10.1155/2016/8108549

Synthetic nanoprobes for biological hydrogen sulfide detection and imaging
Yingzhu Zhou, Federico Mazur, Qingqing Fan and Rona Chandrawati
VIEW, 2022, 3
DOI: 10.1002/VIW.20210008

Garlic and Onions: Their Cancer Prevention Properties
Holly L. Nicastro, Sharon A. Ross and John A. Milner
Cancer Prevention Research, 2015, 8, 181
DOI: 10.1158/1940-6207.CAPR-14-0172

Enhanced Biodesulfurization with a Microbubble Strategy in an Airlift Bioreactor with Haloalkaliphilic Bacterium Thioalkalivibrio versutus D306
Sumit Peh, Tingzhen Mu, Wei Zhong, Maohua Yang, Zheng Chen, Gama Yang, Xuhao Zhao, Moustafa Mohamed Sharshar, Nadia A. Samak and Jianmin Xing
ACS Omega, 2022, 7, 15518
DOI: 10.1021/acsomega.2c00258

Allylation and Alkylation of Biologically Relevant Nucleophiles by Diallyl Sulfides
Kasi Viswanatharaju Ruddraraju, Zachary D. Parsons, Calvin D. Lewis and Kent S. Gates
J. Org. Chem., 2017, 82, 776
DOI: 10.1021/acs.joc.6b02517

Trimethyl Lock: A Multifunctional Molecular Tool for Drug Delivery, Cellular Imaging, and Stimuli‐Responsive Materials
Okoh Adeyi Okoh and Philipp Klahn
ChemBioChem, 2018, 19, 1668
DOI: 10.1002/cbic.201800269

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance
Konstantin Chegaev, Barbara Rolando, Daniela Cortese, Elena Gazzano, Ilaria Buondonno, Loretta Lazzarato, Marilù Fanelli, Claudia M. Hattinger, Massimo Serra, Chiara Riganti, Roberta Fruttero, Dario Ghigo and Alberto Gasco
J. Med. Chem., 2016, 59, 4881
DOI: 10.1021/acs.jmedchem.6b00184

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
Jacek Zielonka, Joy Joseph, Adam Sikora, Micael Hardy, Olivier Ouari, Jeannette Vasquez-Vivar, Gang Cheng, Marcos Lopez and Balaraman Kalyanaraman
Chem. Rev., 2017, 117, 10043
DOI: 10.1021/acs.chemrev.7b00042

Bioelectronic synthesis of hydrogen sulfide enables spatiotemporal regulation of protein modification and cellular redox
Lian Lim, Changho Lee, Jaewoong Lee, Myeongeun Lee, Yongha Kim, Tae Kyoung Lee, Gwangbin Lee, Jinsoo Kim, Sang Yeon Oh, Jihan Kim and Jimin Park
Sci. Adv., 2026, 12
DOI: 10.1126/sciadv.aeb3401

Esterase Activated Carbonyl Sulfide/Hydrogen Sulfide (H2S) Donors
Preeti Chauhan, Prerona Bora, Govindan Ravikumar, Swetha Jos and Harinath Chakrapani
Org. Lett., 2017, 19, 62
DOI: 10.1021/acs.orglett.6b03336

Homocysteine and psoriasis
Xiran Lin, Xianmin Meng and Zhiqi Song
Bioscience Reports, 2019, 39
DOI: 10.1042/BSR20190867

Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy
Christi Cho, Maxwell Zeigler, Stephanie Mizuno, Richard S. Morrison, Rheem A. Totah and Melissa Barker-Haliski
IJMS, 2022, 23, 1434
DOI: 10.3390/ijms23031434

Hydrogen Sulfide-Releasing Carbonic Anhydrase Inhibitors Effectively Suppress Cancer Cell Growth
Alessandro Bonardi, Alessio Nocentini, Viviana de Luca, Clemente Capasso, Eslam B. Elkaeed, Wagdy M. Eldehna and Claudiu T. Supuran
IJMS, 2024, 25, 10006
DOI: 10.3390/ijms251810006

Synthesis and application of a novel fluorescent probe for detection of hydrogen sulfide in real samples
Xiaoju Tan, Tong Hong, Yuchen Jiang, Zhigang Zhao and Zhichuan Shi
International Journal of Environmental Analytical Chemistry, 2024, 104, 5099
DOI: 10.1080/03067319.2022.2118582

Modulation of hydrogen sulfide gasotransmitter limits the proven benefits of garlic
Esma Yagdi Efe, Mario Dicato and Marc Diederich
Phytochem Rev, 2019, 18, 1167
DOI: 10.1007/s11101-019-09634-y

Biothiol-triggered H2S release from a near-infrared fluorescent H2S donor promotes cutaneous wound healing
Xinyue Zhao, Mengbin Ding, Lulu Ning, Fang Yuan, Jingchao Li, Yuan Guo, Yuguang Mu and Jianjian Zhang
Acta Materia Medica, 2022, 1
DOI: 10.15212/AMM-2022-0032

Pre-exposure to hydrogen sulfide modulates the innate inflammatory response to organic dust
Denusha Shrestha, Sanjana Mahadev Bhat, Nyzil Massey, Cristina Santana Maldonado, Wilson K. Rumbeiha and Chandrashekhar Charavaryamath
Cell Tissue Res, 2021, 384, 129
DOI: 10.1007/s00441-020-03333-3

Slow generation of hydrogen sulfide from sulfane sulfurs and NADH models
Bo Peng, Chunrong Liu, Zhen Li, Jacob J. Day, Yun Lu, David J. Lefer and Ming Xian
Bioorganic & Medicinal Chemistry Letters, 2017, 27, 542
DOI: 10.1016/j.bmcl.2016.12.023

Esterase-Triggered Self-Immolative Thiocarbamates Provide Insights into COS Cytotoxicity
Carolyn M. Levinn, Andrea K. Steiger and Michael D. Pluth
ACS Chem. Biol., 2019, 14, 170
DOI: 10.1021/acschembio.8b00981

A review on hydrogen production from hydrogen sulphide by chemical and photochemical methods
Andrea Pietro Reverberi, Jiří Jaromír Klemeš, Petar Sabev Varbanov and Bruno Fabiano
Journal of Cleaner Production, 2016, 136, 72
DOI: 10.1016/j.jclepro.2016.04.139

Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies
Ricardo O. S. Soares, Daniele M. Losada, Maria C. Jordani, Paulo Évora and Orlando Castro-e-Silva
IJMS, 2019, 20, 5034
DOI: 10.3390/ijms20205034

Hydrogen Sulfide: A Robust Combatant against Abiotic Stresses in Plants
Kanika Khanna, Nandni Sharma, Sandeep Kour, Mohd. Ali, Puja Ohri and Renu Bhardwaj
Hydrogen, 2021, 2, 319
DOI: 10.3390/hydrogen2030017

Single-Component Photo-Responsive Template for the Controlled Release of NO and H2S2
Biswajit Roy, Meg Shieh, Shi Xu, Xiang Ni and Ming Xian
J. Am. Chem. Soc., 2023, 145, 277
DOI: 10.1021/jacs.2c09914

Sulfur-containing class of broad-spectrum antivirals improves influenza virus vaccine development
David W. Buchholz, Armando Pacheco, Sreetama Pal, I. Abrrey Monreal, Shi Xu, Brian Imbiakha, Julie Sahler, Mason Jager, Alex Liqi Lai, Erik M. Contreras, Shahrzad Ezzatpour, Brandan Cook, Elshan Ralalage, Qian Liu, Yao Yu Yeo, Andrew Ma, Haewon Byun, Obaed Shah, J. Lizbeth Reyes Zamora, Niraj K. Shil, Sara Jones-Burrage, Suzanne M. Pritchard, Chuntao Yang, Yu Zhao, Zeinab J. Mohamed, Cheyan Xu, Michael J. Jung, Gerlinde R. Van de Walle, Suchetana Mukhopadhyay, Masako Shimamura, Alan G. Goodman, Michele Hardy, Santanu Bose, Anthony V. Nicola, Jack H. Freed, Avery August, Susan Daniel, Petr Chlanda, Jace W. Jones, Ming Xian and Hector C. Aguilar
Nat Commun, 2026, 17
DOI: 10.1038/s41467-025-67775-5

Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules
Jinming Hu, Yuanmeng Fang, Xumin Huang, Ruirui Qiao, John F. Quinn and Thomas P. Davis
Advanced Drug Delivery Reviews, 2021, 179, 114005
DOI: 10.1016/j.addr.2021.114005

Gasotransmitter delivery via self-assembling peptides: Treating diseases with natural signaling gases
Yun Qian and John B. Matson
Advanced Drug Delivery Reviews, 2017, 110-111, 137
DOI: 10.1016/j.addr.2016.06.017

Mesoporous silica materials and nanoparticles as carriers for controlled and site-specific delivery of gaseous signaling molecules
Indranil Chakraborty and Pradip K. Mascharak
Microporous and Mesoporous Materials, 2016, 234, 409
DOI: 10.1016/j.micromeso.2016.07.028

Hydrogen sulfide donor GYY4137 attenuates vascular complications in mesenteric bed of streptozotocin-induced diabetic rats
Hussa Alshahwan, Bedoor Qabazard, Alyaa Mousa, Bindu Chandrasekhar, Krishna Santhosh and Mariam H.M. Yousif
European Journal of Pharmacology, 2022, 933, 175265
DOI: 10.1016/j.ejphar.2022.175265

Postbiotics, Metabolic Signaling, and Cancer
Nikola Vrzáčková, Tomáš Ruml and Jaroslav Zelenka
Molecules, 2021, 26, 1528
DOI: 10.3390/molecules26061528

Recent developments with rhodanine as a scaffold for drug discovery
Danylo Kaminskyy, Anna Kryshchyshyn and Roman Lesyk
Expert Opinion on Drug Discovery, 2017, 12, 1233
DOI: 10.1080/17460441.2017.1388370

Gas Signaling Molecules and Mitochondrial Potassium Channels
Agnieszka Walewska, Adam Szewczyk and Piotr Koprowski
IJMS, 2018, 19, 3227
DOI: 10.3390/ijms19103227

H2S/Curcumin Coreleasing Biomineralized Zinc Sulfide Nanostructures for Diabetic Wound Healing
Shiqi Wu, Yuxuan Ge, Yuan Peng, Yunsheng Chen, Zheng Zhang and Yixin Zhang
ACS Appl. Nano Mater., 2025, 8, 4749
DOI: 10.1021/acsanm.4c07309

Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy (Review)
Abbas Salihi, Mohammed Al‑Naqshabandi, Zhikal Khudhur, Zjwan Housein, Harmand Hama, Ramyar Abdullah, Bashdar Hussen and Twana Alkasalias
Mol Med Rep, 2022, 26
DOI: 10.3892/mmr.2022.12749

Protective or Inhibitory Effect of Pharmacological Therapy on Cardiac Ischemic Preconditioning: A Literature Review
Leonardo Jorge Cordeiro de Paula, Augusto Hiroshi Uchida, Paulo Cury Rezende, Paulo Soares and Thiago Luis Scudeler
CVP, 2022, 20, 409
DOI: 10.2174/1570161120666220819163025

Copper‐Macrophage Crosstalk: Potential Molecular Mechanisms and Therapeutic Applications in Infected Wound Healing
Jianghua Yang, Jiaqi Qin, Bolong Xu, Huiyu Liu and Xianwen Wang
Small, 2025, 21
DOI: 10.1002/smll.202509183

Electrophilic Cyanate As a Recognition Motif for Reactive Sulfur Species: Selective Fluorescence Detection of H2S
Erman Karakuş, Muhammed Üçüncü and Mustafa Emrullahoğlu
Anal. Chem., 2016, 88, 1039
DOI: 10.1021/acs.analchem.5b04163

H2S-Releasing Polymer Micelles for Studying Selective Cell Toxicity
Jeffrey C. Foster, Scott C. Radzinski, Xianlin Zou, Carla V. Finkielstein and John B. Matson
Mol. Pharmaceutics, 2017, 14, 1300
DOI: 10.1021/acs.molpharmaceut.6b01117

Sulfide restrains the growth of Methylocapsa acidiphila converting renewable biogas to single cell protein
Mingyi Xu, Huihui Zhou, Xiaoyong Yang, Irini Angelidaki and Yifeng Zhang
Water Research, 2020, 184, 116138
DOI: 10.1016/j.watres.2020.116138

Hydrogels for Gasotransmitter Delivery: Nitric Oxide, Carbon Monoxide, and Hydrogen Sulfide
Santu Sarkar, Rajnish Kumar and John B. Matson
Macromolecular Bioscience, 2024, 24
DOI: 10.1002/mabi.202300138

Hydrogen sulfide provides intestinal protection during a murine model of experimental necrotizing enterocolitis
Natalie A. Drucker, Amanda R. Jensen, Michael Ferkowicz and Troy A. Markel
Journal of Pediatric Surgery, 2018, 53, 1692
DOI: 10.1016/j.jpedsurg.2017.12.003

Pharmacological induction of mesenchymal-epithelial transition via inhibition of H2S biosynthesis and consequent suppression of ACLY activity in colon cancer cells
Kelly Ascenção, Nahzli Dilek, Fiona Augsburger, Theodora Panagaki, Karim Zuhra and Csaba Szabo
Pharmacological Research, 2021, 165, 105393
DOI: 10.1016/j.phrs.2020.105393

Application of hydrogen sulfide donor conjugates in different diseases
Rui Zhang, Wumei Shi, Xiaoyan Wu, Qingfeng Yu and Ying Xiao
Nitric Oxide, 2025, 154, 128
DOI: 10.1016/j.niox.2024.11.008

Effects of sulfane sulfur content in benzyl polysulfides on thiol-triggered H2S release and cell proliferation
Sarah G. Bolton, Matthew M. Cerda, Annie K. Gilbert and Michael D. Pluth
Free Radical Biology and Medicine, 2019, 131, 393
DOI: 10.1016/j.freeradbiomed.2018.12.025

Thio-ProTide strategy: A novel H2S donor–drug conjugate (DDC) alleviates hepatic injury via innate lysosomal targeting
Haowen Jin, Jie Ma, Bixin Xu, Sitao Xu, Tianyu Hu, Xin Jin, Jiankun Wang, Guangji Wang and Le Zhen
Acta Pharmaceutica Sinica B, 2024, 14, 5341
DOI: 10.1016/j.apsb.2024.10.017

Synthesis of Dithiolethiones and Identification of Potential Neuroprotective Agents via Activation of Nrf2-Driven Antioxidant Enzymes
Zi-Long Song, Feifei Bai, Baoxin Zhang and Jianguo Fang
J. Agric. Food Chem., 2020, 68, 2214
DOI: 10.1021/acs.jafc.9b06360

Supplementation of sperm cryopreservation media with H2S donors enhances sperm quality, reduces oxidative stress, and improves in vitro fertilization outcomes
Asefeh Mohammadi, Farnoosh Jafarpour, Nima Tanhaei Vash, Mehdi Hajian and Mohammad Hossein Nasr-Esfahani
Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-62485-2

Current Approaches and Futuristic Implications for Production and Application of Hydrogen in Agriculture 5.0: A Comprehensive Review
Mohammad Muzamil, Rizwan Ul Zama Banday, Maliqa Majid, Danish Gul, Asima Jillani, Saqib Rashid, Athar Bashir and Kezia Rajan
Turkish Journal of Agricultural Engineering Research, 2025, 6, 179
DOI: 10.46592/turkager.1665288

Reactive sulfur and selenium species in the regulation of bone homeostasis
Annie K. Gilbert, Turner D. Newton, Marian H. Hettiaratchi and Michael D. Pluth
Free Radical Biology and Medicine, 2022, 190, 148
DOI: 10.1016/j.freeradbiomed.2022.08.002

Characterization of Mechanisms of Glutathione Conjugation with Halobenzoquinones in Solution and HepG2 Cells
Wei Wang, Yichao Qian, Jinhua Li, Naif Aljuhani, Arno G. Siraki, X. Chris Le and Xing-Fang Li
Environ. Sci. Technol., 2018, 52, 2898
DOI: 10.1021/acs.est.7b05945

A FRET-based probe for fluorescence sensing of sulfide/sulfite analytes, using a novel long-wavelength water-soluble 7-hydroxycoumarin as reporter fluorophore
Benoît Roubinet, Laetitia Bailly, Emilie Petit, Pierre-Yves Renard and Anthony Romieu
Tetrahedron Letters, 2015, 56, 1015
DOI: 10.1016/j.tetlet.2015.01.042

Experimental study on direct solar photocatalytic water splitting for hydrogen production using surface uniform concentrators
Qingyu Wei, Yan Yang, Haijun Liu, Junyi Hou, Maochang Liu, Fei Cao and Liang Zhao
International Journal of Hydrogen Energy, 2018, 43, 13745
DOI: 10.1016/j.ijhydene.2018.01.135

One- and Two-Photon-Activated Cysteine Persulfide Donors for Biological Targeting
Amrita Chaudhuri, Yarra Venkatesh, Joyjyoti Das, Moumita Gangopadhyay, Tapas K. Maiti and N. D. Pradeep Singh
J. Org. Chem., 2019, 84, 11441
DOI: 10.1021/acs.joc.9b01224

Design, Synthesis, and Cardioprotective Effects ofN-Mercapto-Based Hydrogen Sulfide Donors
Yu Zhao, Chuntao Yang, Chelsea Organ, Zhen Li, Shashi Bhushan, Hiro Otsuka, Armando Pacheco, Jianming Kang, Hector C. Aguilar, David J. Lefer and Ming Xian
J. Med. Chem., 2015, 58, 7501
DOI: 10.1021/acs.jmedchem.5b01033

Therapeutic potential of sulfur-containing natural products in inflammatory diseases
Xu Cao, Lei Cao, Wencan Zhang, Rongzhu Lu, Jin-Song Bian and Xiaowei Nie
Pharmacology & Therapeutics, 2020, 216, 107687
DOI: 10.1016/j.pharmthera.2020.107687

Hydrogen Sulfide Donors Activated by Reactive Oxygen Species
Yu Zhao and Michael D. Pluth
Angewandte Chemie, 2016, 128, 14858
DOI: 10.1002/ange.201608052

Hydrogen Sulfide in Bone Tissue Regeneration and Repair: State of the Art and New Perspectives
Laura Gambari, Brunella Grigolo and Francesco Grassi
IJMS, 2019, 20, 5231
DOI: 10.3390/ijms20205231

A Persulfide Donor Responsive to Reactive Oxygen Species: Insights into Reactivity and Therapeutic Potential
Chadwick R. Powell, Kearsley M. Dillon, Yin Wang, Ryan J. Carrazzone and John B. Matson
Angewandte Chemie, 2018, 130, 6432
DOI: 10.1002/ange.201803087

HS− induced thiolysis reaction to regulate UV- and fluorescence spectra change and their bioimaging in living cells
Qi Zhao, Fangjun Huo, Yongbin Zhang, Yin Wen and Caixia Yin
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 215, 297
DOI: 10.1016/j.saa.2019.02.096

Pharmacological modulation of the hydrogen sulfide (H2S) system by dietaryH2S‐donors: A novel promising strategy in the prevention and treatment of type 2 diabetes mellitus
Eugenia Piragine and Vincenzo Calderone
Phytotherapy Research, 2021, 35, 1817
DOI: 10.1002/ptr.6923

Recent Development of the Molecular and Cellular Mechanisms of Hydrogen Sulfide Gasotransmitter
Jianyun Liu, Fikir M. Mesfin, Chelsea E. Hunter, Kenneth R. Olson, W. Christopher Shelley, John P. Brokaw, Krishna Manohar and Troy A. Markel
Antioxidants, 2022, 11, 1788
DOI: 10.3390/antiox11091788

Photocontrollable water-soluble polymeric hydrogen sulfide (H2S) donor
Zhihui Li, Daai Li, Lin Wang, Chengjie Lu, Pengfei Shan, Xianglong Zou and Zhongyu Li
Polymer, 2019, 168, 16
DOI: 10.1016/j.polymer.2019.02.004

Hydrogen sulphide (H2S) releasing capacity of essential oils isolated from organosulphur rich fruits and vegetables
Dong Liang, Chenhui Wang, Restituto Tocmo, Haixia Wu, Lih-Wen Deng and Dejian Huang
Journal of Functional Foods, 2015, 14, 634
DOI: 10.1016/j.jff.2015.02.007

Cellular Uptake and Antioxidant Activity of H2S-Releasing Tetrapeptide Supramolecular Polymer Nanostructures
Zhao Li, Bushra Tousian, Michal Zaiden, Ishani Sarkar, Clark Vu, Yin Wang, Ronit Bitton and John B. Matson
ACS Materials Lett., 2025, 7, 3141
DOI: 10.1021/acsmaterialslett.5c00921

Diallyl Trisulfide Is a Fast H2S Donor, but Diallyl Disulfide Is a Slow One: The Reaction Pathways and Intermediates of Glutathione with Polysulfides
Dong Liang, Haixia Wu, Ming Wah Wong and Dejian Huang
Org. Lett., 2015, 17, 4196
DOI: 10.1021/acs.orglett.5b01962

Antiproliferative hydrogen sulfide releasing evodiamine derivatives and their apoptosis inducing properties
Xu Hu, Runwei Jiao, Haonan Li, Xianhua Wang, Haoda Lyu, Xiang Gao, Fanxing Xu, Zhanlin Li, Huiming Hua and Dahong Li
European Journal of Medicinal Chemistry, 2018, 151, 376
DOI: 10.1016/j.ejmech.2018.04.009

Synthesis, Spectroscopic, and Structural Characterization of Organyl Disulfanides and a Tetrasulfanide
Stefan Jungen, Eno Paenurk and Peter Chen
Inorg. Chem., 2020, 59, 12322
DOI: 10.1021/acs.inorgchem.0c01426

Development and Application of Carbonyl Sulfide-Based Donors for H2S Delivery
Carolyn M. Levinn, Matthew M. Cerda and Michael D. Pluth
Acc. Chem. Res., 2019, 52, 2723
DOI: 10.1021/acs.accounts.9b00315

Gas‐Releasing Polymer Tubesomes: Boosting Gas Delivery of Nanovehicles via Membrane Stretching
Cuiqin Yang, Yulian Zhang, Miaomiao Xu, Jianfeng Li and Qiang Yan
Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202421405

Discovery of medium ring thiophosphorus based heterocycles as antiproliferative agents
Wei Feng, Wisna Novera, Kaye Peh, Donavan Neo, Pondy Murugappan Ramanujulu, Philip K. Moore, Lih-Wen Deng and Brian W. Dymock
Bioorganic & Medicinal Chemistry Letters, 2017, 27, 967
DOI: 10.1016/j.bmcl.2016.12.079

Controlled-synthesis of alumina-graphene oxide nanocomposite coupled with DNA/ sulfide fluorophore for eco-friendly “Turn off/on” H2S nanobiosensor
Nadia A. Samak, Mohamed S. Selim, Zhifeng Hao and Jianmin Xing
Talanta, 2020, 211, 120655
DOI: 10.1016/j.talanta.2019.120655

Use of gasotransmitters for the controlled release of polymer-based nitric oxide carriers in medical applications
Chungmo Yang, Soohyun Jeong, Seul Ku, Kangwon Lee and Min Hee Park
Journal of Controlled Release, 2018, 279, 157
DOI: 10.1016/j.jconrel.2018.04.025

An insight into prodrug strategy for the treatment of Alzheimer’s disease
Neha V. Bhilare, Vinayak S. Marulkar, Dileep Kumar, Vivekanand K. Chatap, Kashmira S. Patil and Pramodkumar J. Shirote
Med Chem Res, 2022, 31, 383
DOI: 10.1007/s00044-022-02859-1

Boiling enriches the linear polysulfides and the hydrogen sulfide-releasing activity of garlic
Restituto Tocmo, Yuchen Wu, Dong Liang, Vincenzo Fogliano and Dejian Huang
Food Chemistry, 2017, 221, 1867
DOI: 10.1016/j.foodchem.2016.10.076

Time-Gated Luminescence Detection of Enzymatically Produced Hydrogen Sulfide: Design, Synthesis, and Application of a Lanthanide-Based Probe
Yao Yao, Loruhama Delgado-Rivera, Hamid Samareh Afsari, Liang Yin, Gregory R. J. Thatcher, Terry W. Moore and Lawrence W. Miller
Inorg. Chem., 2018, 57, 681
DOI: 10.1021/acs.inorgchem.7b02533

A Persulfide Donor Responsive to Reactive Oxygen Species: Insights into Reactivity and Therapeutic Potential
Chadwick R. Powell, Kearsley M. Dillon, Yin Wang, Ryan J. Carrazzone and John B. Matson
Angew Chem Int Ed, 2018, 57, 6324
DOI: 10.1002/anie.201803087

Co-assembled Nanocarriers of De Novo Thiol-Activated Hydrogen Sulfide Donors with an RGDFF Pentapeptide for Targeted Therapy of Non-Small-Cell Lung Cancer
Hong Chen, Xiaoying Guan, Qianqian Liu, Longcui Yang, Jun Guo, Feng Gao, Yueheng Qi, Xiongting Wu, Feng Zhang and Xiumei Tian
ACS Appl. Mater. Interfaces, 2022, 14, 53475
DOI: 10.1021/acsami.2c14570

Inhibition of Mitochondrial Bioenergetics by Esterase-Triggered COS/H2S Donors
Andrea K. Steiger, Michela Marcatti, Csaba Szabo, Bartosz Szczesny and Michael D. Pluth
ACS Chem. Biol., 2017, 12, 2117
DOI: 10.1021/acschembio.7b00279

Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature
Christina Leichner, Max Jelkmann and Andreas Bernkop-Schnürch
Advanced Drug Delivery Reviews, 2019, 151-152, 191
DOI: 10.1016/j.addr.2019.04.007

Organelle-Targeted H2S Probes Enable Visualization of the Subcellular Distribution of H2S Donors
Leticia A. Montoya and Michael D. Pluth
Anal. Chem., 2016, 88, 5769
DOI: 10.1021/acs.analchem.6b00087

A Sweet H2S/H2O2 Dual Release System and Specific Protein S-Persulfidation Mediated by Thioglucose/Glucose Oxidase
Xiang Ni, Xiaolu Li, Tun-Li Shen, Wei-Jun Qian and Ming Xian
J. Am. Chem. Soc., 2021, 143, 13325
DOI: 10.1021/jacs.1c06372

Targeting Wnt/β-catenin signaling pathway in triple-negative breast cancer by benzylic organotrisulfides: Contribution of the released hydrogen sulfide towards potent anti-cancer activity
Debojit Bhattacherjee, Khyati Raina, Tapas K. Mandal, Rajkumar P. Thummer and Krishna P. Bhabak
Free Radical Biology and Medicine, 2022, 191, 82
DOI: 10.1016/j.freeradbiomed.2022.08.029

Nanomedicine‐Enabled Chemical Regulation of Reactive X Species for Versatile Disease Treatments
Xinyue Dai, Yujie Xie, Wei Feng and Yu Chen
Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202309160

Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release
Ajay Kumar Sharma, Mrutyunjay Nair, Preeti Chauhan, Kavya Gupta, Deepak K Saini and Harinath Chakrapani
Org. Lett., 2017, 19, 4822
DOI: 10.1021/acs.orglett.7b02259

Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis
Alessandro Bonardi, Laura Micheli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Paola Gratteri, Alessio Nocentini and Claudiu T. Supuran
J. Med. Chem., 2022, 65, 13143
DOI: 10.1021/acs.jmedchem.2c00982

Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues
Yueqin Zheng, Bingchen Yu, Ladie Kimberly De La Cruz, Manjusha Roy Choudhury, Abiodun Anifowose and Binghe Wang
Medicinal Research Reviews, 2018, 38, 57
DOI: 10.1002/med.21433

Synthesis and study of thioglycoside conjugates of 4-chloro-1,2-dithiol-3-one as potential cancer-preventive substances in vitro and in vivo
S. N. Fedorov, A. S. Kuzmich, I. G. Agafonova, Yu. E. Sabutskii, A. G. Guzii, R. S. Popov, V. A. Ogurtsov, O. A. Rakitin and S. G. Polonik
Russ Chem Bull, 2022, 71, 489
DOI: 10.1007/s11172-022-3438-x

Decreased bioavailability of hydrogen sulfide links vascular endothelium and atrial remodeling in atrial fibrillation
Megan Watts, Gopi K. Kolluru, Parinita Dherange, Sibile Pardue, Man Si, Xinggui Shen, Krystle Trosclair, John Glawe, Zaki Al-Yafeai, Mazen Iqbal, Brenna H. Pearson, Kathryn A. Hamilton, A. Wayne Orr, Edward Glasscock, Christopher G. Kevil and Paari Dominic
Redox Biology, 2021, 38, 101817
DOI: 10.1016/j.redox.2020.101817

Two-photon ratiometric fluorescent probe based on NBD-amine functionalized semiconducting polymer nanoparticles for real-time imaging of hydrogen sulfide in living cells and zebrafish
Dongmei Wang, Jiajia He and Junyong Sun
Talanta, 2021, 228, 122269
DOI: 10.1016/j.talanta.2021.122269

H2S supplementation: A novel method for successful organ preservation at subnormothermic temperatures
Smriti Juriasingani, Masoud Akbari, Justin YH. Chan, Matthew Whiteman and Alp Sener
Nitric Oxide, 2018, 81, 57
DOI: 10.1016/j.niox.2018.10.004

Development of photo-controllable hydrogen sulfide donor applicable in live cells
Naoki Fukushima, Naoya Ieda, Mitsuyasu Kawaguchi, Kiyoshi Sasakura, Tetsuo Nagano, Kenjiro Hanaoka, Naoki Miyata and Hidehiko Nakagawa
Bioorganic & Medicinal Chemistry Letters, 2015, 25, 175
DOI: 10.1016/j.bmcl.2014.11.084

Hypoxia-Activatable Nanovesicles as In Situ Bombers for Combined Hydrogen-Sulfide-Mediated Respiration Inhibition and Photothermal Therapy
Qi Yu, Le Tu, Ting Zhu, Hongda Zhu, Shujuan Liu, Yao Sun and Qiang Zhao
ACS Appl. Mater. Interfaces, 2022, 14, 50637
DOI: 10.1021/acsami.2c15844

Danger perception and stress response through an olfactory sensor for the bacterial metabolite hydrogen sulfide
Kohei Koike, Seung-Jun Yoo, Katherin Bleymehl, Masayo Omura, Bolek Zapiec, Martina Pyrski, Thomas Blum, Mona Khan, Zhaodai Bai, Trese Leinders-Zufall, Peter Mombaerts and Frank Zufall
Neuron, 2021, 109, 2469
DOI: 10.1016/j.neuron.2021.05.032

Photorelease of Hydrogen Sulfide (H2S) from Stable Water-Soluble Precursors
Kun Wang and Vladimir Popik
J. Org. Chem., 2025, 90, 13938
DOI: 10.1021/acs.joc.5c01997

Hydrogen Sulfide: A Versatile Molecule and Therapeutic Target in Health and Diseases
Aqsa Shahid and Madhav Bhatia
Biomolecules, 2024, 14, 1145
DOI: 10.3390/biom14091145

Hydrogen Sulfide Donors Activated by Reactive Oxygen Species
Yu Zhao and Michael D. Pluth
Angew Chem Int Ed, 2016, 55, 14638
DOI: 10.1002/anie.201608052

The Hidden Role of Hydrogen Sulfide Metabolism in Cancer
Rong-Hsuan Wang, Yu-Hsin Chu and Kai-Ti Lin
IJMS, 2021, 22, 6562
DOI: 10.3390/ijms22126562

Cyclic polysulphide 1,2,4-trithiolane from stinky bean (Parkia speciosa seeds) is a slow releasing hydrogen sulphide (H2S) donor
Dong Liang, Jinsong Bian, Lih-Wen Deng and Dejian Huang
Journal of Functional Foods, 2017, 35, 197
DOI: 10.1016/j.jff.2017.05.040

Synthesis of Cyclic Sulfite Diesters and their Evaluation as Sulfur Dioxide (SO2) Donors
Satish R. Malwal, Kundansingh A. Pardeshi and Harinath Chakrapani
ChemBioChem, 2020, 21, 1201
DOI: 10.1002/cbic.201900614

Role of Hydrogen Sulfide in Myocardial Ischemia–Reperfusion Injury
Peng Zhang, Yue Yu, Pei Wang, Hua Shen, Xinyu Ling, Xiaofei Xue, Qian Yang, Yufeng Zhang, Jian Xiao and Zhinong Wang
Journal of Cardiovascular Pharmacology, 2021, 77, 130
DOI: 10.1097/FJC.0000000000000943

Crescent-Shaped Supramolecular Tetrapeptide Nanostructures
Yin Wang, Zhao Li, Yulia Shmidov, Ryan J. Carrazzone, Ronit Bitton and John B. Matson
J. Am. Chem. Soc., 2020, 142, 20058
DOI: 10.1021/jacs.0c09399

Hydrogen sulfide: Recent development of its dual donors and hybrid drugs
Shi Xu, Meg Shieh, Bindu D. Paul and Ming Xian
British J Pharmacology, 2026, 183, 70
DOI: 10.1111/bph.16211

PGK1 Persulfidation Promotes the Proliferation and Metastasis of Breast Cancer
Chenghua Luo, Mengmeng Zhao, Yalu Wang, Yuxiang Xu, Shuai Chen, Weihua Liang, Kaige Yang and Jianming Hu
Antioxidants & Redox Signaling, 2026, 44, 164
DOI: 10.1177/15230864251394334

Interaction of the hydrogen sulphide inhibitor, propargylglycine (PAG), with hydrogen sulphide on postharvest changes of the green leafy vegetable, pak choy
H.M.S. Al Ubeed, R.B.H. Wills, M.C. Bowyer and J.B. Golding
Postharvest Biology and Technology, 2019, 147, 54
DOI: 10.1016/j.postharvbio.2018.09.011

pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury
Jianming Kang, Zhen Li, Chelsea L. Organ, Chung-Min Park, Chun-tao Yang, Armando Pacheco, Difei Wang, David J. Lefer and Ming Xian
J. Am. Chem. Soc., 2016, 138, 6336
DOI: 10.1021/jacs.6b01373

Hydrogen Sulfide (H2S) Releasing Capacity of Isothiocyanates from Moringa oleifera Lam.
Xiangshe Wang, Yunjiao Liu, Xingdi Liu, Yi Lin, Xueqin Zheng and Yuyun Lu
Molecules, 2018, 23, 2809
DOI: 10.3390/molecules23112809

Evaluation of Thiosaccharides as Carbohydrate-Based Slow-Releasing Hydrogen Sulfide Donors
Stephen Lindahl, Meg Shieh, Iris Yang, Masana Yazaki, Taiming Liu, Charlotte Stang, Austin Sarker-Young, Benjamin Kuran, Jiajun Huang, Yinsheng Wan, Xiang Ni, Mieko Arisawa and Ming Xian
ACS Chem. Biol., 2026, 21, 626
DOI: 10.1021/acschembio.6c00049

Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention
Virendra Tiwari, Manjari Singh, Jitendra K. Rawat, Uma Devi, Rajnish K. Yadav, Subhadeep Roy, Swetlana Gautam, Shubhini A. Saraf, Vikas Kumar, Nazam Ansari, Abdulaziz S. Saeedan and Gaurav Kaithwas
Inflammopharmacol, 2016, 24, 253
DOI: 10.1007/s10787-016-0274-3

The Combination of Oolonghomobisflavan B and Diallyl Disulfide Induces Apoptotic Cell Death via 67-kDa Laminin Receptor/Cyclic Guanosine Monophosphate in Acute Myeloid Leukemia Cells
Jaehoon Bae and Su-Jin Park
CIMB, 2024, 46, 2444
DOI: 10.3390/cimb46030154