Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells

Julian Laux, Michael Forster, Laura Riexinger, Anna Schwamborn, Jamil Guezguez, Christina Pokoj, Mark Kudolo, Lena M. Berger, Stefan Knapp, Dieter Schollmeyer, Jan Guse, Michael Burnet and Stefan A. Laufer

ACS Pharmacol. Transl. Sci., 2022, 5, 573
DOI: 10.1021/acsptsci.2c00054

Tofacitinib and Analogs as Inhibitors of the Histone Kinase Prk1 (Pkn1)

Dmytro Ostrovskyi, Tobias Rumpf, Julia Eib, Alexandre Lumbroso, Inna Slynko, Susan Klaeger, Stephanie Heinzlmeir, Michael Forster, Matthias Gehringer, Ellen Pfaffenrot, Silke Mona Bauer, Karin Schmidtkunz, Sandra Wenzler, Eric Metzger, Bernhard Kuster, Stefan Laufer, Roland Schüle, Wolfgang Sippl, Bernhard Breit and Manfred Jung

Future Med. Chem., 2016, 8, 1537
DOI: 10.4155/fmc-2016-0132

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Michael Forster, Apirat Chaikuad, Silke M. Bauer, Julia Holstein, Matthew B. Robers, Cesear R. Corona, Matthias Gehringer, Ellen Pfaffenrot, Kamran Ghoreschi, Stefan Knapp and Stefan A. Laufer

Cell Chemical Biology, 2016, 23, 1335
DOI: 10.1016/j.chembiol.2016.10.008

Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors

Dan Su, Yu-Qiao Gao, Yong-Jie Deng, Han-Hui Zhang, You-Ru Wu, Ying Hu and Quan-Xi Mei

Evidence-Based Complementary and Alternative Medicine, 2019, 2019, 1
DOI: 10.1155/2019/4982062

Polymethacrylate Sphere-Based Assay for Ultrasensitive miRNA Detection

Samira Hosseini, Patricia Vázquez-Villegas, Richard C. Willson, Marco Rito-Palomares, Margarita Sanchez-Dominguez, Leo H. Koole, Marc J. Madou and Sergio O. Martínez-Chapa

Advances in Polymer Technology, 2020, 2020, 1
DOI: 10.1155/2020/7310657

Simultaneous Sensing of H2O, D2O and HOD through Peroxo Vibrations

Srimanta Pal and Arun Chattopadhyay

ChemPhysChem, 2023, 24
DOI: 10.1002/cphc.202200684

Solution-Phase Parallel Synthesis of Ruxolitinib-Derived Janus Kinase Inhibitors via Copper-Catalyzed Azide–Alkyne Cycloaddition

Matthias Gehringer, Michael Forster and Stefan A. Laufer

ACS Comb. Sci., 2015, 17, 5
DOI: 10.1021/co500122h

Screening assays for tyrosine kinase inhibitors: A review

Juan Gao, Jingyi Jian, Zhengjin Jiang and Ann Van Schepdael

Journal of Pharmaceutical and Biomedical Analysis, 2023, 223, 115166
DOI: 10.1016/j.jpba.2022.115166

Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen Synthase Kinase-3β Inhibitors

Stanislav Andreev, Tatu Pantsar, Francesco Ansideri, Mark Kudolo, Michael Forster, Dieter Schollmeyer, Stefan A. Laufer and Pierre Koch

Molecules, 2019, 24, 2331
DOI: 10.3390/molecules24122331

Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

Michael Forster, Xiaojun Julia Liang, Martin Schröder, Stefan Gerstenecker, Apirat Chaikuad, Stefan Knapp, Stefan Laufer and Matthias Gehringer

IJMS, 2020, 21, 9269
DOI: 10.3390/ijms21239269

Intrant ELISA: A Novel Approach to Fabrication of Electrospun Fiber Mat-Assisted Biosensor Platforms and Their Integration within Standard Analytical Well Plates

Samira Hosseini, Pedram Azari, Mohammad Aeinehvand, Hussin Rothan, Ivan Djordjevic, Sergio Martinez-Chapa and Marc Madou

Applied Sciences, 2016, 6, 336
DOI: 10.3390/app6110336

HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents

Karoline B. Waitman, Larissa C. de Almeida, Marina C. Primi, Jorge A.E.G. Carlos, Claudia Ruiz, Thales Kronenberger, Stefan Laufer, Marcia Ines Goettert, Antti Poso, Sandra V. Vassiliades, Vinícius A.M. de Souza, Mônica F.Z. J. Toledo, Neuza M.A. Hassimotto, Michael D. Cameron, Thomas D. Bannister, Letícia V. Costa-Lotufo, João A. Machado-Neto, Maurício T. Tavares and Roberto Parise-Filho

European Journal of Medicinal Chemistry, 2024, 263, 115935
DOI: 10.1016/j.ejmech.2023.115935

Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs

Samira Hosseini, Patricia Vázquez-Villegas and Sergio O. Martínez-Chapa

Applied Sciences, 2017, 7, 863
DOI: 10.3390/app7080863

Development, Optimization, and Structure–Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine Scaffold

Michael Forster, Apirat Chaikuad, Teodor Dimitrov, Eva Döring, Julia Holstein, Benedict-Tilman Berger, Matthias Gehringer, Kamran Ghoreschi, Susanne Müller, Stefan Knapp and Stefan A. Laufer

J. Med. Chem., 2018, 61, 5350
DOI: 10.1021/acs.jmedchem.8b00571