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Potential Use of Supercharging Agents for Improved Mass Spectrometric Analysis of Monoclonal Antibodies and Antibody–Drug Conjugates

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Strong Acid Anions Significantly Increasing the Charge State of Proteins during Electrospray Ionization

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Anal. Chem., 2020, 92, 1770
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Resolving the Discrepancies Between Empirical and Rayleigh Charge Limiting Models for Globular Proteins

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Distinguishing Protein Chemical Topologies Using Supercharging Ion Mobility Spectrometry‐Mass Spectrometry

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On the Mechanism of Theta Capillary Nanoelectrospray Ionization for the Formation of Highly Charged Protein Ions Directly from Native Solutions

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Highly Charged Protein Ions: The Strongest Organic Acids to Date

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Supercharging Synthetic Polymers: Mass Spectrometric Access to Nonpolar Synthetic Polymers

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Effects of solvent composition on ionization and fragmentation within the solution-cathode glow discharge

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Protein–Small Molecule Interactions in Native Mass Spectrometry

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Distinguishing Protein Chemical Topologies Using Supercharging Ion Mobility Spectrometry‐Mass Spectrometry

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Top-Down Analysis of Supercharged Proteins Using Collision-, Electron-, and Photon-Based Activation Methods

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Generating Supercharged Protein Ions for Breath Analysis by Extractive Electrospray Ionization Mass Spectrometry

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Microscale differential ion mobility spectrometry for field deployable chemical analysis

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Supercharging protein ions in native mass spectrometry using theta capillary nanoelectrospray ionization mass spectrometry and cyclic alkylcarbonates

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Analytica Chimica Acta, 2018, 1003, 1
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Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates

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Variable Mixing with Theta Emitter Mass Spectrometry: Changing Solution Flow Rates with Emitter Position

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Mechanistic Study of Enhanced Protonation by Chromium(III) in Electrospray Ionization: A Superacid Bound to a Peptide

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Suppression of Protein Structural Perturbations in Native Electrospray Ionization during the Final Evaporation Stages Revealed by Molecular Dynamics Simulations

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The use of chromium(III) complexes to enhance peptide protonation by electrospray ionization mass spectrometry

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Challenges for the in vivo quantification of brain neuropeptides using microdialysis sampling and LC–MS

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Bioanalysis, 2016, 8, 1965
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On the mechanism of protein supercharging in electrospray ionisation mass spectrometry: Effects on charging of additives with short- and long-chain alkyl constituents with carbonate and sulphite terminal groups

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Simple Protein Analysis by Droplet Paper Spray Ionization Mass Spectrometry with Polyolefin Silica-Based Paper

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Origin and Prediction of Highly Specific Bond Cleavage Sites in the Thermal Activation of Intact Protein Ions

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Supercharging reagents in LC-MS/MS hormone analyses: Enhancing ionization, not limit of quantification

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Nanodiscs and mass spectrometry: Making membranes fly

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Supercharging of Proteins by Salts during Polarity Reversed Nano-Electrospray Ionization

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Cytotoxicity of α-Helical, Staphylococcus aureus PSMα3 Investigated by Post-Ion-Mobility Dissociation Mass Spectrometry

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Anal. Chem., 2020, 92, 11802
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Multiple solvent elution, a method to counter the effects of coelution and ion suppression in LC-MS analysis in bottom up proteomics

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Extended Protein Ions Are Formed by the Chain Ejection Model in Chemical Supercharging Electrospray Ionization

Micah T. Donor, Simon A. Ewing, Muhammad A. Zenaidee, William A. Donald and James S. Prell

Anal. Chem., 2017, 89, 5107
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Highly Charged Protein Ions: The Strongest Organic Acids to Date

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Angewandte Chemie, 2017, 129, 8642
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Dual Electrospray Ionization Enhancement of Proteins Enabled by DMSO Supercharging Reagent

Dmitry B. Eremin and Valery V. Fokin

J. Am. Soc. Mass Spectrom., 2022, 33, 203
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Internal Fragments Generated by Electron Ionization Dissociation Enhance Protein Top-Down Mass Spectrometry

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Supercharging and multiple reaction monitoring of high‐molecular‐weight intact proteins using triple quadrupole mass spectrometry

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Rapid Comm Mass Spectrometry, 2019, 33, 821
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Protonation isomers of highly charged protein ions can be separated in FAIMS-MS

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Pulsed Nanoelectrospray Ionization Boosts Ion Signal in Whole Protein Mass Spectrometry

Qinwen Liu, Ezaz Ahmed, K. M. Mohibul Kabir, Xiaojing Huang, Dan Xiao, John Fletcher and William A. Donald

Applied Sciences, 2021, 11, 10883
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A Comprehensive Guide for Performing Sample Preparation and Top-Down Protein Analysis

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Proteomes, 2017, 5, 11
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Chemical Additives Enable Native Mass Spectrometry Measurement of Membrane Protein Oligomeric State within Intact Nanodiscs

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J. Am. Chem. Soc., 2019, 141, 1054
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Modulation of Protein Fragmentation Through Carbamylation of Primary Amines

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J. Am. Soc. Mass Spectrom., 2017, 28, 1587
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Charge Retention/Charge Depletion in ESI-MS: Experimental Evidence

Marco Thinius, Christine Polaczek, Markus Langner, Steffen Bräkling, Alexander Haack, Hendrik Kersten and Thorsten Benter

J. Am. Soc. Mass Spectrom., 2020, 31, 773
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Approaches to Heterogeneity in Native Mass Spectrometry

Amber D. Rolland and James S. Prell

Chem. Rev., 2022, 122, 7909
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