Sihan Ji, Xianglong Zhao, Pengfei Li, Peng Zheng, Haibin Tang, Vincenzo Amendola, Dongshi Zhang, Yunyu Cai, Kun Ma, Changhao Wang, Xiaohu Cheng, Shuxian Wei, Lingli Wu, Yixing Ye, Junfeng Wang and Changhao Liang

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202509431

Robust oxidase mimicking activity of protamine-stabilized platinum nanoparticles units and applied for colorimetric sensor of trypsin and inhibitor

Xiaoyun Lin, Zhenmao Zhu, Chengfei Zhao, Shaoguang Li, Qicai Liu, Ailin Liu, Liqing Lin and Xinhua Lin

Sensors and Actuators B: Chemical, 2019, 284, 346
DOI: 10.1016/j.snb.2018.12.109

Latest advances in biomimetic nanomaterials for diagnosis and treatment of cardiovascular disease

Yuxuan Gong, Huaying Liu, Shen Ke, Li Zhuo and Haibin Wang

Front. Cardiovasc. Med., 2023, 9
DOI: 10.3389/fcvm.2022.1037741

Iron Single-Atom Anchored on N-Doped Carbon Nanozymes for Chlorpyrifos Detection and Antibacterial Applications

Enxiang Ren, Xing Zhang, Guo-Ping Lu, Muhammad Sohail, Jun Hu, Zhong Chen, Daidi Fan and Yamei Lin

ACS Appl. Nano Mater., 2023, 6, 15038
DOI: 10.1021/acsanm.3c02630

A colorimetric sensing strategy based on chitosan-stabilized platinum nanoparticles for quick detection of α-glucosidase activity and inhibitor screening

Qin-Qin Yang, Shao-Bin He, Yi-Lin Zhang, Min Li, Xiu-Hua You, Bo-Wen Xiao, Liu Yang, Zhi-Qiang Yang, Hao-Hua Deng and Wei Chen

Anal Bioanal Chem, 2024, 416, 6001
DOI: 10.1007/s00216-024-05198-9

l-Histidine-protected copper nanoparticles as a fluorescent probe for sensing ferric ions

Shu Min Lin, Shuo Geng, Na Li, Shi Gang Liu, Nian Bing Li and Hong Qun Luo

Sensors and Actuators B: Chemical, 2017, 252, 912
DOI: 10.1016/j.snb.2017.06.079

Cobalt-based zeolitic imidazole framework incorporated with well-dispersed bimetallic nanoparticles/ions as a multifunctional nanozyme for the degradation of environmental pollutants and discrimination of various phenolic substances

Yuwei Guan, Yuexiang Lu, Jingye Zhao, Wei Huang and Yueying Liu

Chemical Engineering Journal, 2023, 465, 142703
DOI: 10.1016/j.cej.2023.142703

Oxidase-Like Catalytic Performance of Nano-MnO2 and Its Potential Application for Metal Ions Detection in Water

Kai Sun, Qingzhu Liu, Rui Zhu, Qi Liu, Shunyao Li, Youbin Si and Qingguo Huang

International Journal of Analytical Chemistry, 2019, 2019, 1
DOI: 10.1155/2019/5416963

Co3O4/CuO hollow nanocage hybrids with high oxidase-like activity for biosensing of dopamine

Yunxia Zhuang, Xiaodan Zhang, Qiumeng Chen, Siqi Li, Haiyan Cao and Yuming Huang

Materials Science and Engineering: C, 2019, 94, 858
DOI: 10.1016/j.msec.2018.10.038

An Enhanced Photothermal Therapeutic Iridium Hybrid Platform Reversing the Tumor Hypoxic Microenvironment

Hang Zhang, Xiaoxiao Chen, Shengliang Li, Jianliang Shen and Zong-Wan Mao

Molecules, 2022, 27, 2629
DOI: 10.3390/molecules27092629

MOF-derived N-doped porous carbon with active magnesium sites as an efficient oxidase mimic for biosensing

Yuejie Hou, Yuwan Lu, Xiaodan Zhang and Yuming Huang

Sensors and Actuators B: Chemical, 2022, 370, 132409
DOI: 10.1016/j.snb.2022.132409

Enhanced His@AuNCs oxidase-like activity by reduced graphene oxide and its application for colorimetric and electrochemical detection of nitrite

Lu Liu, Jie Du, Wen-e Liu, Yongliang Guo, Guofan Wu, Weinan Qi and Xiaoquan Lu

Anal Bioanal Chem, 2019, 411, 2189
DOI: 10.1007/s00216-019-01655-y

Sodium Alginate Modified Platinum Nanozymes With Highly Efficient and Robust Oxidase-Like Activity for Antioxidant Capacity and Analysis of Proanthocyanidins

Shao-Bin He, Liu Yang, Xiu-Ling Lin, Hua-Ping Peng, Zhen Lin, Hao-Hua Deng, Wei Chen and Guo-Lin Hong

Front. Chem., 2020, 8
DOI: 10.3389/fchem.2020.00654

Glutathione-templated blue emitting copper nanoclusters as selective fluorescent probe for quantification of nitrofurazone

Shen Zhang, Yuzhe Li, Chenglu Fan, Jinqi Liu and Yuyu Guo

Chemical Physics Letters, 2023, 825, 140614
DOI: 10.1016/j.cplett.2023.140614

Corrosion‐Activated Chemotherapeutic Function of Nanoparticulate Platinum as a Cisplatin Resistance‐Overcoming Prodrug with Limited Autophagy Induction

Hsien‐Jen Cheng, Te‐Haw Wu, Chih‐Te Chien, Hai‐Wei Tu, Ting‐Shan Cha and Shu‐Yi Lin

Small, 2016, 12, 6124
DOI: 10.1002/smll.201602374

Protein-protected metal nanoclusters as diagnostic and therapeutic platforms for biomedical applications

Iman Zare, Daniel M. Chevrier, Anna Cifuentes-Rius, Nasrin Moradi, Yunlei Xianyu, Subhadip Ghosh, Laura Trapiella-Alfonso, Ye Tian, Alireza Shourangiz-Haghighi, Saptarshi Mukherjee, Kelong Fan and Michael R. Hamblin

Materials Today, 2023, 66, 159
DOI: 10.1016/j.mattod.2020.10.027

PdCu nanoparticles with multienzymatic activity to treat tumors through the synergistic photothermal and chemodynamic therapy

Wende Fan, Yulin Xie, Yinyuan Zhang, Xiaoju Li and Chunxia Li

Mater. Res. Express, 2024, 11, 065402
DOI: 10.1088/2053-1591/ad51da

Label-free colorimetric sensor for mercury(II) and DNA on the basis of mercury(II) switched-on the oxidase-mimicking activity of silver nanoclusters

Guang-Li Wang, Lu-Yi Jin, Xiu-Ming Wu, Yu-Ming Dong and Zai-Jun Li

Analytica Chimica Acta, 2015, 871, 1
DOI: 10.1016/j.aca.2015.02.027

Platinum group element-based nanozymes for biomedical applications: an overview

Shao-Bin He, Liu Yang, Meng-Ting Lin, Paramasivam Balasubramanian, Hua-Ping Peng, Ye Kuang, Hao-Hua Deng and Wei Chen

Biomed. Mater., 2021, 16, 032001
DOI: 10.1088/1748-605X/abc904

Preparation of Platinum Nanoclusters Using Acid Red G as a Stabilizer and Detection of Tetracycline

Qian Sun, De Xing Chen, Yu Ting Tao, Xing Ping Yang and Yun Fei Long

J Anal Chem, 2025, 80, 1647
DOI: 10.1134/S1061934825700844

Solids Go Bio: Inorganic Nanoparticles as Enzyme Mimics

Ruben Ragg, Muhammad N. Tahir and Wolfgang Tremel

Eur J Inorg Chem, 2016, 2016, 1906
DOI: 10.1002/ejic.201501237

Improving peroxidase activity of gold nanorod nanozymes by dragging substrates to the catalysis sites via cysteine modification

Rui Cai, Xinshuang Gao, Chenqi Zhang, Zhijian Hu, Yinglu Ji, Jianbo Liu and Xiaochun Wu

Nanotechnology, 2021, 32, 485702
DOI: 10.1088/1361-6528/ac1e53

A Review on Fabrication of Platinum Nanoparticles and Their Potential Implementations in Biomedical Field

Fawad Ahmad, Fizza Arif, Sadaf Munir, Muhammad Imran Khan, Suchandra Bhattacharjee, Sushmita Gajurel, Abdul Rehman Buzdar and Abdallah Shanableh

Zeitschrift anorg allge chemie, 2026, 652
DOI: 10.1002/zaac.202500195

Pt–Se nanostructures with oxidase-like activity and their application in a selective colorimetric assay for mercury(II)

Leilei Guo, Long Mao, Kaixun Huang and Hongmei Liu

J Mater Sci, 2017, 52, 10738
DOI: 10.1007/s10853-017-1181-8

Cu,Zn,I-Doped Carbon Dots with Boosted Triple Antioxidant Nanozyme Activity for Treatment of DSS-Induced Colitis

Yifan Cui, Dezhi Yang, Qiulan Li, Zhongmei Peng, Zitao Zhong, Yuzhu Song, Qinqin Han and Yaling Yang

ACS Appl. Mater. Interfaces, 2024, 16, 32619
DOI: 10.1021/acsami.4c03627

Selective detection of nitrofurantoin by histidine‐capped silver nanoclusters with blue luminescence

Yuyu Guo, Yiqing Chu, Xiaojuan Sun, Songhao Cao, Xin Li and Xinyue Li

Luminescence, 2023, 38, 796
DOI: 10.1002/bio.4508

Efficient synthesis of graphene oxide-supported molybdenum compounds exhibiting excellent peroxidase-like activity

Dheeraj and Lata Rana

Polyhedron, 2024, 262, 117175
DOI: 10.1016/j.poly.2024.117175

Trypsin encapsulated gold-silver bimetallic nanoclusters for recognition of quinalphos via fluorescence quenching and of Zn2+ and Cd2+ ions via fluorescence enhancement

Soujanya Akavaram, Mittal L. Desai, Tae-Jung Park, Z.V.P. Murthy and Suresh Kumar Kailasa

Journal of Molecular Liquids, 2021, 327, 114830
DOI: 10.1016/j.molliq.2020.114830

Recent advances on signal amplification strategies in photoelectrochemical sensing of microRNAs

Fei Li, Yunlei Zhou, Huanshun Yin and Shiyun Ai

Biosensors and Bioelectronics, 2020, 166, 112476
DOI: 10.1016/j.bios.2020.112476

Enzyme-like nanomaterials-integrated microfluidic technology for bioanalysis

Fengyang Zhao, Wenli Wu, Mei Zhao, Shichao Ding, Yuehe Lin, Qiongzheng Hu and Li Yu

TrAC Trends in Analytical Chemistry, 2023, 158, 116833
DOI: 10.1016/j.trac.2022.116833

Catalytic nanozymes for central nervous system disease

Ke Chen, Si Sun, Junying Wang and Xiao-Dong Zhang

Coordination Chemistry Reviews, 2021, 432, 213751
DOI: 10.1016/j.ccr.2020.213751

Colorimetric and SERS dual-mode detection of GSH in human serum based on AuNPs@Cu-porphyrin MOF nanozyme

Kexi Sun, Chao Liu, Yi Cao, Jianxia Zhu, Jialin Li and Qing Huang

Analytica Chimica Acta, 2024, 1304, 342552
DOI: 10.1016/j.aca.2024.342552

Medium-entropy nanoenzyme with high oxidase-like activity for sensitive detection of interleukin-6 based on ELISA

Lifang Chen, Jiaqi Chen, Ying Lei, Pengcheng Lin, Donglin Cao, Wei Xiao and Liangshan Hu

Anal Bioanal Chem, 2025, 417, 5171
DOI: 10.1007/s00216-025-06054-0

Trifolium-like Platinum Nanoparticle-Mediated Photothermal Therapy Inhibits Tumor Growth and Osteolysis in a Bone Metastasis Model

Changping Wang, Xiaopan Cai, Jishen Zhang, Xinyu Wang, Yu Wang, Huyifeng Ge, Wangjun Yan, Quan Huang, Jianru Xiao, Qiang Zhang and Yiyun Cheng

Small, 2015, 11, 2080
DOI: 10.1002/smll.201403315

Fluorescent papain-encapsulated platinum nanoclusters for sensing lysozyme in biofluid and gram-positive bacterial identification

Xin Chang, Peng Gao, Quanfa Li, Hongming Liu, Huanhuan Hou, Shuang Wu, Jie Chen, Lu Gan, Ming Zhao, Dagan Zhang, Shuping Sun and Baojuan Wang

Sensors and Actuators B: Chemical, 2021, 345, 130363
DOI: 10.1016/j.snb.2021.130363

An Emerging Nanozyme Class for à la carte Enzymatic‐Like Activities based on Protein‐Metal Nanocluster Hybrids

Rocío López‐Domene, Silvia Vázquez‐Díaz, Evgenii Modin, Ana Beloqui and Aitziber L. Cortajarena

Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202301131

Synergistic integration of metal nanoclusters and biomolecules as hybrid systems for therapeutic applications

Peng Gao, Xin Chang, Dagan Zhang, Yafei Cai, Gen Chen, Hao Wang and Tianfu Wang

Acta Pharmaceutica Sinica B, 2021, 11, 1175
DOI: 10.1016/j.apsb.2020.12.004

Pt Nanoparticles with High Oxidase-Like Activity and Reusability for Detection of Ascorbic Acid

Qin Cheng, Yong Yang, Yusi Peng and Meng Liu

Nanomaterials, 2020, 10, 1015
DOI: 10.3390/nano10061015

Smartphone-assisted colorimetric sensor based on single-atom Cu–C–N nanozyme for mercury (II) ions detection

Jia Ge, Yating Yuan, Hao Yang, Ruijie Deng, Zhaohui Li and Yu Yang

Materials Today Chemistry, 2024, 37, 102037
DOI: 10.1016/j.mtchem.2024.102037

Label-free cascade amplification strategy for sensitive visual detection of thrombin based on target-triggered hybridization chain reaction-mediated in situ generation of DNAzymes and Pt nanochains

Ying Zhang, Wang Ren, Hong Qun Luo and Nian Bing Li

Biosensors and Bioelectronics, 2016, 80, 463
DOI: 10.1016/j.bios.2016.02.016

Highly stable and throughput flow injection amperometric uric acid electrochemical sensor based on a novel AuPtNPs@OMC nanocomposite

Thanomwan Kueasom, Thanawath Tuntiwongmetee, Nuttakorn Junlapak, Natha Nontipichet, Supapich Romportong, Panote Thavarungkul, Suntisak Khumngern and Apon Numnuam

Microchemical Journal, 2025, 218, 115246
DOI: 10.1016/j.microc.2025.115246

Rapid chemical reduction synthesis of copper nanoclusters with blue fluorescence for highly sensitive detection of furazolidone

Yuyu Guo, Jiancheng Wang, Lili Zhang and Junkai Wang

Luminescence, 2024, 39
DOI: 10.1002/bio.4702

Highly sensitive colorimetric detection of arsenite based on reassembly-induced oxidase-mimicking activity inhibition of dithiothreitol-capped Pd nanozyme

Xuechao Xu, Linjie Wang, Xiaobo Zou, Shuwen Wu, Jianming Pan, Xin Li and Xiangheng Niu

Sensors and Actuators B: Chemical, 2019, 298, 126876
DOI: 10.1016/j.snb.2019.126876

Improved enzymatic assay for hydrogen peroxide and glucose by exploiting the enzyme-mimicking properties of BSA-coated platinum nanoparticles

Shao-Bin He, Rui-Ting Chen, Yan-Yu Wu, Gang-Wei Wu, Hua-Ping Peng, Ai-Lin Liu, Hao-Hua Deng, Xing-Hua Xia and Wei Chen

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3939-y

BSA-stabilized Pt nanozyme for peroxidase mimetics and its application on colorimetric detection of mercury(II) ions

Wei Li, Bin Chen, Haixiang Zhang, Yanhua Sun, Jun Wang, Jinli Zhang and Yan Fu

Biosensors and Bioelectronics, 2015, 66, 251
DOI: 10.1016/j.bios.2014.11.032

Graphyne-supported manganese single-atom nanozyme sensor array for bisphenol identification

Jianing Xia, Ruixue Fu, Zhen Li, Yaping Ding, Hongbin Zhao and Daixin Ye

Talanta, 2025, 285, 127326
DOI: 10.1016/j.talanta.2024.127326

Rational Design of N-Doped Carbon Nanocage-Equipped Co-Nx Active Sites for Oxidase Mimicking and Sensing Applications

Qian Wang, Qiutong Li, Yuwan Lu, Xiaodan Zhang and Yuming Huang

ACS Sustainable Chem. Eng., 2021, 9, 7668
DOI: 10.1021/acssuschemeng.1c02635

Atomically precise metal cluster enzymes for pathological tissue regeneration

Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang and Peng Yu

BMEMat, 2026
DOI: 10.1002/bmm2.70073

Gold–Platinum Bimetallic Nanoclusters for Oxidase-like Catalysis

Chun-Xia Zhang, Yan-Cai Gao, Hong-Wei Li and Yuqing Wu

ACS Appl. Nano Mater., 2020, 3, 9318
DOI: 10.1021/acsanm.0c01965

Supramolecular self-assembly of high-loaded horseradish peroxidase and biorecognized antibody into Au/polydopamine nanocomposites for sensitive immunoassay of Escherichia coli O157:H7 in milk

Bolong Fang, Yuzhi Li, Xiaole Zhao, Yan Liu, Lin Xu, Qiao Wang, Xin Liu, Zhiyong Gong and Weihua Lai

Journal of Dairy Science, 2025, 108, 3419
DOI: 10.3168/jds.2024-25518

Colorimetric determination of melamine based on the reversal of the mercury(II) induced inhibition of the light-triggered oxidase-like activity of gold nanoclusters

Gen-Xia Cao, Xiu-Ming Wu, Yu-Ming Dong, Zai-Jun Li and Guang-Li Wang

Microchim Acta, 2016, 183, 441
DOI: 10.1007/s00604-015-1669-3

Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor

Xiaoyun Lin, Zhenmao Zhu, Dan Lin, Qiaozhen Bao, Yaoran Gao, Qicai Liu, Ailin Liu, Liqing Lin and Xinhua Lin

Talanta, 2021, 234, 122647
DOI: 10.1016/j.talanta.2021.122647

Bimodal determination of immunoglobulin E by fluorometry and ICP-MS by using platinum nanoclusters as a label in an immunoassay

Ana Lores-Padín, María Cruz-Alonso, Héctor González-Iglesias, Beatriz Fernández and Rosario Pereiro

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3868-9

Nanozyme catalysis-assisted ratiometric multicolor sensing of heparin based on target-specific electrostatic-induced aggregation

Xiangheng Niu, Mengzhu Wang, Hengjia Zhu, Peng Liu, Jianming Pan and Bangxiang Liu

Talanta, 2022, 238, 123003
DOI: 10.1016/j.talanta.2021.123003

Oxidase Mimetic Activity of a Metalloporphyrin-Containing Porous Organic Polymer and Its Applications for Colorimetric Detection of Both Ascorbic Acid and Glutathione

Ding Guo, Cheng Li, Genyan Liu, Xiaogang Luo and Fengshou Wu

ACS Sustainable Chem. Eng., 2021, 9, 5412
DOI: 10.1021/acssuschemeng.1c00419

A Sustainable Biomineralization Approach for the Synthesis of Highly Fluorescent Ultra-Small Pt Nanoclusters

Rajkamal Balu, Robert Knott, Christopher M. Elvin, Anita J. Hill, Namita R. Choudhury and Naba K. Dutta

Biosensors, 2019, 9, 128
DOI: 10.3390/bios9040128

Ascorbate Oxidase Mimetic Activity of Copper(II) Oxide Nanoparticles

Shao‐Bin He, Ai‐Ling Hu, Quan‐Quan Zhuang, Hua‐Ping Peng, Hao‐Hua Deng, Wei Chen and Guo‐Lin Hong

ChemBioChem, 2020, 21, 978
DOI: 10.1002/cbic.201900595

A smartphone-integrated colorimetric quantitative analysis platform based on oxidase-like Ce(IV)-ATP-Tris CPNs/CNF test strip for detection of inorganic arsenic in rice

Linjie Wang, Juanli Yang, Yue Yan, Yuan-Song Zhang and Xuechao Xu

Analytica Chimica Acta, 2022, 1227, 340308
DOI: 10.1016/j.aca.2022.340308

Synthesis, Structural Analysis, and Peroxidase-Mimicking Activity of AuPt Branched Nanoparticles

Silvia Nuti, Javier Fernández-Lodeiro, Jose M. Palomo, José-Luis Capelo-Martinez, Carlos Lodeiro and Adrián Fernández-Lodeiro

Nanomaterials, 2024, 14, 1166
DOI: 10.3390/nano14131166

Bifunctionalized Mesoporous Silica‐Supported Gold Nanoparticles: Intrinsic Oxidase and Peroxidase Catalytic Activities for Antibacterial Applications

Yu Tao, Enguo Ju, Jinsong Ren and Xiaogang Qu

Advanced Materials, 2015, 27, 1097
DOI: 10.1002/adma.201405105

Three-dimensional flower-like multifunctional adsorbents with excellent sorptive removal and colorimetric detection of arsenate

Xuechao Xu, Jialu Luo, Siting Wei, Xiaobo Zou, Xiangheng Niu and Jianming Pan

Chemical Engineering Journal, 2020, 398, 125649
DOI: 10.1016/j.cej.2020.125649

Pt and ZnFe2O4 Nanoparticles Immobilized on Carbon for the Detection of Glutathione

Bing Bian, Xixi Zhu, Qiong Wu, Yue Liu, Shiwei Liu, Qingyun Liu and Shitao Yu

ACS Appl. Nano Mater., 2021, 4, 9479
DOI: 10.1021/acsanm.1c01954

Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy

Xiaodong Zhang, Xiaokai Chen and Yanli Zhao

Nano-Micro Lett., 2022, 14
DOI: 10.1007/s40820-022-00828-2

A sensitive dopamine colorimetric sensing platform based on Co3ZnC/co/co-N-C nanozyme with high oxidase-like activity

Jiawen Xu, Ze Lv, Hong Xu and Zhiping Mao

Microchemical Journal, 2025, 215, 114361
DOI: 10.1016/j.microc.2025.114361

Lysozyme-Decorated Gold and Molybdenum Bimetallic Nanoclusters for the Selective Detection of Bilirubin as a Jaundice Biomarker

Shraddha Borse, Zagabathuni Venkata Panchakshari Murthy, Tae-Jung Park and Suresh Kumar Kailasa

ACS Appl. Nano Mater., 2021, 4, 11949
DOI: 10.1021/acsanm.1c02515

The photo-activated oxidase-like activity of gold nanoclusters: Implication for singlet oxygen generation

Po-Yen Yu, Yu-Shan Chen, Hui-Hsuan Yu, Fang-I Chen, Zhi-Wen Chen and Ching-Ping Liu

Journal of Photochemistry and Photobiology A: Chemistry, 2022, 432, 114063
DOI: 10.1016/j.jphotochem.2022.114063

Nanozymes With Osteochondral Regenerative Effects: An Overview of Mechanisms and Recent Applications

Xueheng Sun, Xiang Xu, Xiaokun Yue, Tianchang Wang, Zhaofei Wang, Changru Zhang and Jinwu Wang

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202301924

Two-dimensional nanozyme nanoarchitectonics customized electrochemical bio diagnostics and lab-on-chip devices for biomarker detection

Thenmozhi Rajarathinam, Sivaguru Jayaraman, Chang-Seok Kim, Jang-Hee Yoon and Seung-Cheol Chang

Advances in Colloid and Interface Science, 2025, 341, 103474
DOI: 10.1016/j.cis.2025.103474

Colorimetric detection of ascorbic acid and alkaline phosphatase activity based on the novel oxidase mimetic of Fe–Co bimetallic alloy encapsulated porous carbon nanocages

Tengteng Wu, Zhangyan Ma, Peipei Li, Meiling Liu, Xiaoying Liu, Haitao Li, Youyu Zhang and Shouzhuo Yao

Talanta, 2019, 202, 354
DOI: 10.1016/j.talanta.2019.05.034

Optical and Thermal Properties of Laser-Ablated Platinum Nanoparticles Graphene Oxide Composite

Amir Reza Sadrolhosseini, Mina Habibiasr, Suhaidi Shafie, Hassan Solaimani and Hong Ngee Lim

IJMS, 2019, 20, 6153
DOI: 10.3390/ijms20246153

Tryptophan-functionalized gold nanoclusters used as a fluorescence sensor for alizarin determination

Shen Zhang, Zhuo Wang and Tianyu Miao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 335, 125963
DOI: 10.1016/j.saa.2025.125963

Smartphone-assisted copper nanoclusters fluorescent sensing platform for visual determination of Congo red

Shen Zhang, Zhuo Wang, Guiyu Meng and Chaoying Yang

Colloids and Surfaces B: Biointerfaces, 2025, 251, 114610
DOI: 10.1016/j.colsurfb.2025.114610

Green production of functionalized few-layer borophene decorated with cerium-doped iron oxide nanoparticles for repeatable hydrogen peroxide detection

Yingjie Bu and Beom Soo Kim

Biosensors and Bioelectronics, 2024, 260, 116448
DOI: 10.1016/j.bios.2024.116448

Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury

Tianbao Ye, Cheng Chen, Di Wang, Chengjie Huang, Zhiwen Yan, Yu Chen, Xian Jin, Xiuyuan Wang, Xianting Ding and Chengxing Shen

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-45927-3

A colorimetric smartphone-based platform for pesticides detection using Fe-N/C single-atom nanozyme as oxidase mimetics

Jia Ge, Like Yang, Zhaohui Li, Yi Wan, Dongsheng Mao, Ruijie Deng, Qi Zhou, Yu Yang and Weihong Tan

Journal of Hazardous Materials, 2022, 436, 129199
DOI: 10.1016/j.jhazmat.2022.129199

Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics

Duo Jin, Manman Liu, Meng Zhang, Wenxin Yu, Jiaji Yu, Aizong Shen, Junjie Cheng and Yangzhong Liu

Advanced Drug Delivery Reviews, 2023, 192, 114648
DOI: 10.1016/j.addr.2022.114648

Research Progress in Iron-Based Nanozymes: Catalytic Mechanisms, Classification, and Biomedical Applications

Ruixue Fu, Zijian Ma, Hongbin Zhao, Huan Jin, Ya Tang, Ting He, Yaping Ding, Jiujun Zhang and Daixin Ye

Anal. Chem., 2023, 95, 10844
DOI: 10.1021/acs.analchem.3c01005

Ratiometric Colorimetric Detection of Nitrite Realized by Stringing Nanozyme Catalysis and Diazotization Together

Mengzhu Wang, Peng Liu, Hengjia Zhu, Bangxiang Liu and Xiangheng Niu

Biosensors, 2021, 11, 280
DOI: 10.3390/bios11080280

Pt Colloidosomes with Broadband Absorption for Near‐Infrared Light Photocatalysis Through D‐Band Hot‐Carriers Generation

Sihan Ji, Xianglong Zhao, Pengfei Li, Peng Zheng, Haibin Tang, Vincenzo Amendola, Dongshi Zhang, Yunyu Cai, Kun Ma, Changhao Wang, Xiaohu Cheng, Shuxian Wei, Lingli Wu, Yixing Ye, Junfeng Wang and Changhao Liang

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202509431

Controlled preparation and application of glutathione capped gold and platinum alloy nanoclusters with high peroxidase-like activity

Yan-Cai Gao, Chong Wang, Chun-Xia Zhang, Hong-Wei Li and Yuqing Wu

Journal of Materials Science & Technology, 2022, 109, 140
DOI: 10.1016/j.jmst.2021.08.074

Nanozymes: A New Disease Imaging Strategy

Peixia Wang, Tao Wang, Juanji Hong, Xiyun Yan and Minmin Liang

Front. Bioeng. Biotechnol., 2020, 8
DOI: 10.3389/fbioe.2020.00015

The ultrathin palladium nanosheets for sensitive and visual Hg2+ detection in the food chain

Lulu Kong, Chongchong Wang, Weijie Yang, Lin Zhou and Shaohua Wei

Journal of Hazardous Materials, 2022, 427, 128135
DOI: 10.1016/j.jhazmat.2021.128135

Novel blue-emitting probes of polyethyleneimine-capped copper nanoclusters for fluorescence detection of quercetin

Shen Zhang, Junhong Li, Suiyuan Huang, Xinru Ma and Caifeng Zhang

Chem. Pap., 2021, 75, 3761
DOI: 10.1007/s11696-021-01624-9

Dual-Enzyme Characteristics of Polyvinylpyrrolidone-Capped Iridium Nanoparticles and Their Cellular Protective Effect against H2O2-Induced Oxidative Damage

Hua Su, Dan-Dan Liu, Meng Zhao, Wei-Liang Hu, Shan-Shan Xue, Qian Cao, Xue-Yi Le, Liang-Nian Ji and Zong-Wan Mao

ACS Appl. Mater. Interfaces, 2015, 7, 8233
DOI: 10.1021/acsami.5b01271

Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and their Application to Catalytic Oxygen Reduction and Cancer Imaging

Fatemeh Molaabasi, Morteza Sarparast, Mojtaba Shamsipur, Leila Irannejad, Ali Akbar Moosavi-Movahedi, Abouzar Ravandi, Behnam Hajipour Verdom and Reza Ghazfar

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-32918-w

Synthesis of transition metal sulfide functionalized hierarchically porous carbons and their application as colorimetric-electrochemical dual-mode nanozyme sensing platform for dopamine

Weijie Fu, Kai Zhang, Xiaohua Zhang, Guorong Fan, Zongde Wang, Shangxing Chen, Yangping Wen and Peng Wang

Electrochimica Acta, 2023, 437, 141535
DOI: 10.1016/j.electacta.2022.141535

Protein‐protected metal nanoclusters: An emerging ultra‐small nanozyme

Xiangqin Meng, Iman Zare, Xiyun Yan and Kelong Fan

WIREs Nanomed Nanobiotechnol, 2020, 12
DOI: 10.1002/wnan.1602

Advances in design and preparation of nanozymes and their applications for constructing higher sensitive lateral flow assays

Haiyin Li, Yue Peng, Xinda Huang, Rongyan Wan, Li Zhang, Xuan Wang, Lirong Han, Linsen Li, Chuanfeng Wang and Jianling Chen

Coordination Chemistry Reviews, 2024, 510, 215797
DOI: 10.1016/j.ccr.2024.215797

Biotemplated Platinum Nanozymes: Synthesis, Catalytic Regulation and Biomedical Applications

Yanli Lei, Lihong Yu, Zeyang Yang, Ke Quan and Zhihe Qing

ChemBioChem, 2024, 25
DOI: 10.1002/cbic.202400548

Tailoring of active metal sites on nanozymes for chemiluminescence assays: From nanoparticles to isolated atoms

Hui Ouyang and Zhifeng Fu

TrAC Trends in Analytical Chemistry, 2023, 169, 117382
DOI: 10.1016/j.trac.2023.117382

Mesoporous Core–Shell Pd@Pt Nanospheres as Oxidase Mimics with Superhigh Catalytic Efficiency at Room Temperature

Jingyun Zhang, Yajun Zhong, Chunyan Zhang, Junyu Zhang and Zhenjing Zhuang

J. Phys. Chem. Lett., 2022, 13, 2137
DOI: 10.1021/acs.jpclett.1c03921

Acetaminophen sensor based on the oxidase-like activity and interference self-elimination ability of chondroitin sulfate-modified platinum nanozyme

Shao-Bin He, Liu Yang, Meng-Ting Lin, Hamada A.A. Noreldeen, Ru-Xin Yu, Hua-Ping Peng, Hao-Hua Deng and Wei Chen

Sensors and Actuators B: Chemical, 2021, 347, 130627
DOI: 10.1016/j.snb.2021.130627

In Situ Synthesis of 3D Au@Pt Nanozyme Hydrogel SERS Substrates for Highly Sensitive and Quantitative Sensing

Qian-Jiao Qi, Peng-Cheng Guan, Yu-Xuan Zhang, Yi-Fan Yu, Ge Zhang, Jia-Sheng Lin, Yue-Jiao Zhang and Jian-Feng Li

ACS Sens., 2025, 10, 8694
DOI: 10.1021/acssensors.5c02616

Protein-supported transition metal catalysts: Preparation, catalytic applications, and prospects

Tianyou Chen, Yan Peng, Meishuang Qiu, Changfeng Yi and Zushun Xu

International Journal of Biological Macromolecules, 2023, 230, 123206
DOI: 10.1016/j.ijbiomac.2023.123206

Colorimetric assay of heparin in plasma based on the inhibition of oxidase-like activity of citrate-capped platinum nanoparticles

Jyun-Guo You, Yao-Wen Liu, Chi-Yu Lu, Wei-Lung Tseng and Cheng-Ju Yu

Biosensors and Bioelectronics, 2017, 92, 442
DOI: 10.1016/j.bios.2016.10.082

Protein-Assisted Osmium Nanoclusters with Intrinsic Peroxidase-like Activity and Extrinsic Antifouling Behavior

Shao-Bin He, Meng-Ting Lin, Liu Yang, Hamada A. A. Noreldeen, Hua-Ping Peng, Hao-Hua Deng and Wei Chen

ACS Appl. Mater. Interfaces, 2021, 13, 44541
DOI: 10.1021/acsami.1c11907

Colorimetric sensing of biomarkers based on the enzyme-mimetic activity of metal nanoclusters

Nan Gao, Jiaqi Xu, Xiaodan Li, Guixia Ling and Peng Zhang

Chemical Engineering Journal, 2023, 465, 142817
DOI: 10.1016/j.cej.2023.142817

Boosted solar water oxidation steered by atomically precise alloy nanocluster

Xian Yan, Huawei Xie, Gao Wu and Fang-Xing Xiao

Chinese Chemical Letters, 2025, 36, 110279
DOI: 10.1016/j.cclet.2024.110279

A single-nanozyme colorimetric array based on target-induced differential surface passivation for quantification and discrimination of Cl−, Br− and I− ions

Linjie Wang, Xuechao Xu, Peng Liu, Mengzhu Wang, Xiangheng Niu and Jianming Pan

Analytica Chimica Acta, 2021, 1160, 338451
DOI: 10.1016/j.aca.2021.338451

Jyun-Guo You, Yen-Ting Wang and Wei-Lung Tseng

ACS Appl. Mater. Interfaces, 2018, 10, 37846
DOI: 10.1021/acsami.8b13497

Colorimetric determination of As(III) based on 3-mercaptopropionic acid assisted active site and interlayer channel dual-masking of Fe-Co-layered double hydroxides with oxidase-like activity

Xuechao Xu, Xiaobo Zou, Shuwen Wu, Linjie Wang, Jianming Pan, Minjin Xu, Wen Shan, Xin Li and Xiangheng Niu

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-019-3835-5

Advances in oxidase-mimicking nanozymes: Classification, activity regulation and biomedical applications

Yu Chong, Qiang Liu and Cuicui Ge

Nano Today, 2021, 37, 101076
DOI: 10.1016/j.nantod.2021.101076

Glutathione protected bimetallic gold-platinum nanoclusters with near-infrared emission for ratiometric determination of silver ions

Yan-Cai Gao, Chong Wang, Chun-Xia Zhang, Hong-Wei Li and Yuqing Wu

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-04712-5

Sensitive and highly selective biosensor based on innovative V2O5 nanoparticles for detection of glutathione

Han Lu, Zhenbo Xiang and Qiang Ren

Asia-Pacific J Chem Eng, 2024, 19
DOI: 10.1002/apj.3081

Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme

Wenhui Gao, Jiuyang He, Lei Chen, Xiangqin Meng, Yana Ma, Liangliang Cheng, Kangsheng Tu, Xingfa Gao, Cui Liu, Mingzhen Zhang, Kelong Fan, Dai-Wen Pang and Xiyun Yan

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-35828-2

Cobalt phthalocyanine encapsulation boosts oxidase-like activity of single-atom Co N C nanozyme for fluorescence sensing of tetracycline

Shuyan Xiao, Siyi Liu, Mingqin Kang, Jing Liu and Zhongping Dong

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 346, 126869
DOI: 10.1016/j.saa.2025.126869

Fabrication of Fe-doped cobalt zeolitic imidazolate framework derived from Co(OH)2 for degradation of tetracycline via peroxymonosulfate activation

Qi Hu, Jiao Cao, Zhaohui Yang, Weiping Xiong, Zhengyong Xu, Peipei Song, Meiying Jia, Yanru Zhang, Haihao Peng and Ansong Wu

Separation and Purification Technology, 2021, 259, 118059
DOI: 10.1016/j.seppur.2020.118059

Modified jute for adsorption and in situ reduction to prepare metal nanozymes for nitrite detection

Ningning Feng, Ke Xu, Guozhen Wang, Yihai Zeng, Renzhi Zeng, Xin Liang, Haiyan Wu, Hongwei Liu and Jianping Xie

Food Chemistry, 2025, 488, 144817
DOI: 10.1016/j.foodchem.2025.144817

Progress and Trend on the Regulation Methods for Nanozyme Activity and Its Application

Li Hou, Gaoyan Jiang, Ying Sun, Xuanhan Zhang, Juanjuan Huang, Shendong Liu, Tianran Lin, Fanggui Ye and Shulin Zhao

Catalysts, 2019, 9, 1057
DOI: 10.3390/catal9121057

Carbon-based materials of waste PVC dechlorination for colorimetric Hg2+ detection by regulation of aptamer dimension

Yingying Qi, Zefeng Xing, Furong Xiu, Xue Bai and Xiang Gao

Journal of Environmental Chemical Engineering, 2025, 13, 116565
DOI: 10.1016/j.jece.2025.116565

Colorimetric assay of l-cysteine based on peroxidase-mimicking DNA-Ag/Pt nanoclusters

Liang-Liang Wu, Li-Ying Wang, Zheng-Jun Xie, Na Pan and Chi-Fang Peng

Sensors and Actuators B: Chemical, 2016, 235, 110
DOI: 10.1016/j.snb.2016.05.069

Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications

Yanyan Huang, Jinsong Ren and Xiaogang Qu

Chem. Rev., 2019, 119, 4357
DOI: 10.1021/acs.chemrev.8b00672

A Remarkably Efficient MnFe2O4‐based Oxidase Nanozyme

Amit A. Vernekar, Tandrila Das, Sourav Ghosh and Govindasamy Mugesh

Chemistry An Asian Journal, 2016, 11, 72
DOI: 10.1002/asia.201500942

Ultrasmall Pt Nanoclusters as Robust Peroxidase Mimics for Colorimetric Detection of Glucose in Human Serum

Lihua Jin, Zheng Meng, Yongqing Zhang, Shijie Cai, Zaihua Zhang, Cong Li, Li Shang and Yehua Shen

ACS Appl. Mater. Interfaces, 2017, 9, 10027
DOI: 10.1021/acsami.7b01616

Electrodeposition-Assisted Rapid Preparation of Pt Nanocluster/3D Graphene Hybrid Nanozymes with Outstanding Multiple Oxidase-Like Activity for Distinguishing Colorimetric Determination of Dihydroxybenzene Isomers

Na Qiu, Yan Liu and Rong Guo

ACS Appl. Mater. Interfaces, 2020, 12, 15553
DOI: 10.1021/acsami.9b23546

Gold-Platinum Nanoparticles with Core-Shell Configuration as Efficient Oxidase-like Nanosensors for Glutathione Detection

Javier Bonet-Aleta, Jose I. Garcia-Peiro, Silvia Irusta and Jose L. Hueso

Nanomaterials, 2022, 12, 755
DOI: 10.3390/nano12050755

Switching Peroxidase-Mimic Activity of Protein Stabilized Platinum Nanozymes by Sulfide Ions: Substrate Dependence, Mechanism, and Detection

Yan Liu, Yuanlin Zheng, Ding Ding and Rong Guo

Langmuir, 2017, 33, 13811
DOI: 10.1021/acs.langmuir.7b03430

Multifunctional Scaffold Comprising Metal–Organic Framework, Hydrogel, and Demineralized Bone Matrix for the Treatment of Steroid‐Induced Femoral Head Necrosis

Liangjie Bai, Xiaolei Zhang, Wei Shen, Peng Wang, Xin Yin, Jianing Liu, Hailun Xu, Bing Liu, Zhentao Man and Wei Li

Small, 2025, 21
DOI: 10.1002/smll.202407758

Precision Metal Nanoclusters Meet Proteins: Crafting Next-Gen Hybrid Materials

Bihan Zhang, Zhenghan Liu, Ruixuan Zhang, Qiaofeng Yao and Jianping Xie

ACS Nano, 2025, 19, 3997
DOI: 10.1021/acsnano.4c15366

Bioactive metallic nanozymes-based electrochemical biosensors for biomarker detection: Progress and prospects

Runan Tan, Panpan Jiang, Nan Gao, Zhiwei Cai, Halina Grushevskaya, Yuxiang Wu, Hanping He, Yunbin He and Gang Chang

Nano Materials Science, 2025
DOI: 10.1016/j.nanoms.2024.07.005

The peroxidase and oxidase-like activity of NiCo2O4 mesoporous spheres: Mechanistic understanding and colorimetric biosensing

Li Su, Wenpei Dong, Chengke Wu, Yijun Gong, Yan Zhang, Ling Li, Guojiang Mao and Suling Feng

Analytica Chimica Acta, 2017, 951, 124
DOI: 10.1016/j.aca.2016.11.035

Synergistic enhancement of immunological responses triggered by hyperthermia sensitive Pt NPs via NIR laser to inhibit cancer relapse and metastasis

Jie Yu, Sha Liu, Yupeng Wang, Xidong He, Qingfei Zhang, Yanxin Qi, Dongfang Zhou, Zhigang Xie, Xiaoyuan Li and Yubin Huang

Bioactive Materials, 2022, 7, 389
DOI: 10.1016/j.bioactmat.2021.05.030

Iso‐Nanozymes of Atomically Precise Copper Nanoclusters

Jing Sun, Mengke Wang, Zong‐Jie Guan, Yunqing Kang, Xueli Sun, Yishu Wang, Rong Huo, Xuekun Gong, Xiaoxuan Xu, Chengrui Xin, Simin Li, Yusuke Yamauchi, Nanfeng Zheng, Xiyun Yan, Qingxiang Guo and Hui Shen

Aggregate, 2026, 7
DOI: 10.1002/agt2.70271

Enhanced oxidase-like activity of selenium nanoparticles stabilized by chitosan and application in a facile colorimetric assay for mercury (II)

Hui Cao, Junying Xiao and Hongmei Liu

Biochemical Engineering Journal, 2019, 152, 107384
DOI: 10.1016/j.bej.2019.107384

Oxidase-like MOF-818 Nanozyme with High Specificity for Catalysis of Catechol Oxidation

Minghua Li, Jinxing Chen, Weiwei Wu, Youxing Fang and Shaojun Dong

J. Am. Chem. Soc., 2020, 142, 15569
DOI: 10.1021/jacs.0c07273

Stimuli-responsive colorimetric sensor based on bifunctional pyrophosphate-triggered controlled release and enhancing activity of CoOOH nanozyme

Yanyun Zou, Jinyang Chen, Qingli Chai, Ting Zhu, Shasha Zeng and Yucheng Liu

Sensors and Actuators B: Chemical, 2022, 369, 132215
DOI: 10.1016/j.snb.2022.132215

Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment

Yu Chong, Xing Dai, Ge Fang, Renfei Wu, Lin Zhao, Xiaochuan Ma, Xin Tian, Sangyun Lee, Chao Zhang, Chunying Chen, Zhifang Chai, Cuicui Ge and Ruhong Zhou

Nat Commun, 2018, 9
DOI: 10.1038/s41467-018-07257-z

Colorimetric determination of cysteine based on inhibition of GSH-Au/Pt NCs as peroxidase mimic

Jian-Jun Li, Dan Qiao, Shou-Zhi Yang, Guo-Jun Weng, Jian Zhu and Jun-Wu Zhao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 248, 119257
DOI: 10.1016/j.saa.2020.119257

Synthesis of silver nanocrystal with an excellent oxidase-like activity and its application in colorimetric detection of D-penicillamine

Xu Dan, Li Ruiyi, Wang Qinsheng, Yang Yongqiang, Wang Guangli and Li Zaijun

Microchemical Journal, 2021, 166, 106204
DOI: 10.1016/j.microc.2021.106204

Pt/NiCo2O4 nanocomposite with extremely low Pt loading as an oxidase-like nanozyme for colorimetric detection of acetaminophen in natural water

Yue Wu, Wanru Wang, Siya Ye, Kanwal Iqbal, Li Liu, Guoyu Qiu and Weichun Ye

Journal of the Taiwan Institute of Chemical Engineers, 2023, 152, 105183
DOI: 10.1016/j.jtice.2023.105183

Recent advances in templated synthesis of metal nanoclusters and their applications in biosensing, bioimaging and theranostics

Zhenjie Qiao, Jian Zhang, Xin Hai, Yongcun Yan, Weiling Song and Sai Bi

Biosensors and Bioelectronics, 2021, 176, 112898
DOI: 10.1016/j.bios.2020.112898

Chicken egg white mediated synthesis of platinum nanoclusters for the selective detection of carbidopa

Shraddha Borse, Z.V.P. Murthy and Suresh Kumar Kailasa

Optical Materials, 2020, 107, 110085
DOI: 10.1016/j.optmat.2020.110085