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Organoboron synthesis via ring opening coupling reactions

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Eco-friendly chemoselective N-functionalization of isatins mediated by supported KF in 2-MeTHF

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The renaissance of strained 1-azabicyclo[1.1.0]butanes as useful reagents for the synthesis of functionalized azetidines

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Org. Biomol. Chem., 2020, 18, 5798
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Recent developments in the utility of saturated azaheterocycles in peptidomimetics

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Org. Biomol. Chem., 2022, 20, 963
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Structural and mechanistic studies of the base-induced Sommelet–Hauser rearrangement of N-α-branched benzylic azetidine-2-carboxylic acid-derived ammonium salts

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Org. Biomol. Chem., 2017, 15, 6668
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Easy access to constrained peptidomimetics and 2,2-disubstituted azetidines by the unexpected reactivity profile of α-lithiated N-Boc-azetidines

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Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide

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Org. Biomol. Chem., 2014, 12, 2180
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A convenient enantioselective CBS-reduction of arylketones in flow-microreactor systems

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Org. Biomol. Chem., 2016, 14, 4304
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Recent advances in the chemistry of metallated azetidines

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Org. Biomol. Chem., 2017, 15, 34
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Site‐Selective Carbonylation of Azetidines via Copper‐Catalyzed Difluorocarbene Insertion

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Angew Chem Int Ed, 2025, 64
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2-Arylazetidines as ligands for nicotinic acetylcholine receptors

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Chem Heterocycl Comp, 2017, 53, 329
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Reagent/Substituent Switching Approach for the Synthesis of Substituted 1,3,4‐Oxadiazole/1,3,4‐Oxadiazoline and 1,2,4‐Triazole Derivatives from N‐Substituted Hydrazides

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ChemInform Abstract: Regioselective Functionalization of 2‐Arylazetidines: Evaluating the ortho‐Directing Ability of the Azetidinyl Ring and the α‐Directing Ability of the N‐Substituent.

Leonardo Degennaro, Marina Zenzola, Piera Trinchera, Laura Carroccia, Arianna Giovine, Giuseppe Romanazzi, Aurelia Falcicchio and Renzo Luisi

ChemInform, 2014, 45
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Exploiting structural and conformational effects for a site-selective lithiation of azetidines

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Pure and Applied Chemistry, 2016, 88, 631
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Targeting a Mirabegron precursor by BH3-mediated continuous flow reduction process

Sonia De Angelis, Claudia Carlucci, Modesto de Candia, Gabriele Rebuzzini, Paolo Celestini, Massimiliano Riscazzi, Renzo Luisi and Leonardo Degennaro

Catalysis Today, 2018, 308, 81
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A Decarboxylative Cross-Coupling Platform To Access 2-Heteroaryl Azetidines: Building Blocks with Application in Medicinal Chemistry

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Stereo- and Enantioselective Addition of Organolithiums to 2-Oxazolinylazetidines as a Synthetic Route to 2-Acylazetidines

Pantaleo Musci, Marco Colella, Flavio Fanelli, Angela Altomare, Luisa Pisano, Claudia Carlucci, Renzo Luisi and Leonardo Degennaro

Front. Chem., 2019, 7
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Development of a Continuous Flow Synthesis of 2-Substituted Azetines and 3-Substituted Azetidines by Using a Common Synthetic Precursor

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J. Org. Chem., 2021, 86, 13943
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Chemoselective Additions of Chloromethyllithium Carbenoid to Cyclic Enones: A Direct Access to Chloromethyl Allylic Alcohols

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Harnessing the ortho‐Directing Ability of the Azetidine Ring for the Regioselective and Exhaustive Functionalization of Arenes

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Recent advances in benzylic and heterobenzylic lithiation

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Amine Protection/α-Activation with the tert-Butoxythiocarbonyl Group: Application to Azetidine Lithiation–Electrophilic Substitution

David M. Hodgson, Claire L. Mortimer and Jeffrey M. McKenna

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Site‐Selective Carbonylation of Azetidines via Copper‐Catalyzed Difluorocarbene Insertion

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Computational NMR as Useful Tool for Predicting Structure and Stereochemistry of Four‐Membered Sulfur Heterocycles

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Dynamic Phenomena and Complexation Effects in the α-Lithiation and Asymmetric Functionalization of Azetidines

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Molecules, 2022, 27, 2847
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Regio- and Diastereoselective Synthesis of 2-Arylazetidines: Quantum Chemical Explanation of Baldwin’s Rules for the Ring-Formation Reactions of Oxiranes

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J. Org. Chem., 2020, 85, 11226
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Regio- and Stereoselective Synthesis of Sulfur-Bearing Four-Membered Heterocycles: Direct Access to 2,4-Disubstituted Thietane 1-Oxides

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J. Org. Chem., 2015, 80, 12201
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Complexation Phenomena and Dynamics at Work in the Lithiation Reactions of Small‐Ring Heterocycles: Regio‐ and Stereoselectivity

Vito Capriati, Saverio Florio and Renzo Luisi

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Synthesis of Sulfoximine Carbamates by Rhodium-Catalyzed Nitrene Transfer of Carbamates to Sulfoxides

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J. Org. Chem., 2015, 80, 6391
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Functionalization of four-membered cyclic sulfoximines by a convenient lithiation/trapping sequence

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Chem Heterocycl Comp, 2017, 53, 322
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Directed Metalation of 1-Ester-Substituted Indolizines: Base/Electrophile-Controlled Regioselective Functionalization

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Synthesis of chiral Azetidine and its application in asymmetric synthesis

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α- and α′-Lithiation–Electrophile Trapping of N-Thiopivaloyl and N-tert-Butoxythiocarbonyl α-Substituted Azetidines: Rationalization of the Regiodivergence Using NMR and Computation

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Palladium-Catalyzed Hiyama Cross-Couplings of Arylsilanes with 3-Iodoazetidine: Synthesis of 3-Arylazetidines

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Facile Synthesis of Azetidine Nitrones and Diastereoselective Conversion into Densely Substituted Azetidines

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Facile Synthesis of Azetidine Nitrones and Diastereoselective Conversion into Densely Substituted Azetidines

Tyler W. Reidl, Jongwoo Son, Donald J. Wink and Laura L. Anderson

Angewandte Chemie, 2017, 129, 11737
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Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

Arianna Giovine, Marilena Muraglia, Marco Florio, Antonio Rosato, Filomena Corbo, Carlo Franchini, Biagia Musio, Leonardo Degennaro and Renzo Luisi

Molecules, 2014, 19, 11505
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Use of azetidine scaffolds in stereoselective transformations (microreview)

Renzo Luisi and Leonardo Degennaro

Chem Heterocycl Comp, 2018, 54, 400
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Ligand‐Controlled Palladium‐Catalyzed Pyridylation of 1‐tert‐Butoxycarbonyl‐3‐iodoazetidine: Regioselective Synthesis of 2‐ and 3‐Heteroarylazetidines

Yudan Zhang, Zhiyue Geng, Jingya Li, Dapeng Zou, Yangjie Wu and Yusheng Wu

Adv Synth Catal, 2017, 359, 390
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