Clostridium perfringens epsilon toxin: The third most potent bacterial toxin known

Guilherme Guerra Alves, Ricardo Andrez Machado de Ávila, Carlos Delfin Chávez-Olórtegui and Francisco Carlos Faria Lobato

Anaerobe, 2014, 30, 102
DOI: 10.1016/j.anaerobe.2014.08.016

Clearance of Damaged Mitochondria Through PINK1 Stabilization by JNK and ERK MAPK Signaling in Chlorpyrifos-Treated Neuroblastoma Cells

Jae Hyeon Park, Juyeon Ko, Yun Sun Park, Jungyun Park, Jungwook Hwang and Hyun Chul Koh

Mol Neurobiol, 2017, 54, 1844
DOI: 10.1007/s12035-016-9753-1

Cellular effects of epsilon toxin on the cell viability and oxidative stress of normal and lung cancer cells

Farzaneh Motafeghi, Parham Mortazavi, Mobin Mahdavi and Mohammad Shokrzadeh

Microbial Pathogenesis, 2022, 169, 105649
DOI: 10.1016/j.micpath.2022.105649

PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction

Yun Sun Park, Su Eun Choi and Hyun Chul Koh

Toxicology Letters, 2018, 284, 120
DOI: 10.1016/j.toxlet.2017.12.004

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins

Mauricio A. Navarro, Bruce A. McClane and Francisco A. Uzal

Toxins, 2018, 10, 212
DOI: 10.3390/toxins10050212

Mechanisms of intestinal epithelial cell damage by Clostridium perfringens

Lanxin Ou, Bijin Ye, Mingfei Sun, Nanshan Qi, Juan Li, Minna Lv, Xuhui Lin, Haiming Cai, Junjing Hu, Yongle Song, Xiangjie Chen, Yibin Zhu, Lijun Yin, Jianfei Zhang, Shenquan Liao and Haoji Zhang

Anaerobe, 2024, 87, 102856
DOI: 10.1016/j.anaerobe.2024.102856

PPAR-γ activation attenuates deltamethrin-induced apoptosis by regulating cytosolic PINK1 and inhibiting mitochondrial dysfunction

Juyeon Ko, Jae Hyeon Park, Yun Sun Park and Hyun Chul Koh

Toxicology Letters, 2016, 260, 8
DOI: 10.1016/j.toxlet.2016.08.016

Identification of effective inhibitors against epsilon toxin (ETX) of Clostridium perfringens: Virtual screening and molecular dynamics simulation

Atefe Panahipoor Javaherdehi, Zahra Sadat Hashemi, Sepideh Khaleghi and Gholamreza Bayazian

Toxicon, 2025, 264, 108463
DOI: 10.1016/j.toxicon.2025.108463

The pore structure of Clostridium perfringens epsilon toxin

Christos G. Savva, Alice R. Clark, Claire E. Naylor, Michel R. Popoff, David S. Moss, Ajit K. Basak, Richard W. Titball and Monika Bokori-Brown

Nat Commun, 2019, 10
DOI: 10.1038/s41467-019-10645-8

Overview of Bacterial Protein Toxins from Pathogenic Bacteria: Mode of Action and Insights into Evolution

Michel R. Popoff

Toxins, 2024, 16, 182
DOI: 10.3390/toxins16040182

The Effect of Necrotic Enteritis Challenge on Production Performance, Cecal Microbiome, and Cecal Tonsil Transcriptome in Broilers

Gabriel Akerele, Walid Al Hakeem, Jeferson Lourenco and Ramesh Selvaraj

Pathogens, 2022, 11, 839
DOI: 10.3390/pathogens11080839

Active principles and mechanism of action of epsilon toxin from Clostridium perfringens

Elena Negru, Sonia Beşleagă, Teodor Ionescu, Dragoş Cobzariu, Maria‑Rodica Gurău, Georgeta Ştefan, Mihai Daneş and Doina Daneş

Practica Veterinara.ro, 2024, 4, 35
DOI: 10.26416/PV.46.4.2024.10384

Cellular vacuolation and mitochondrial-associated factors induced by Clostridium perfringens epsilon toxin detected using acoustic flow cytometry

Marina C. Ferrarezi, Vera C.L.M. Curci and Tereza C. Cardoso

Anaerobe, 2013, 24, 55
DOI: 10.1016/j.anaerobe.2013.09.009

FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells

Si Yeon Park and Hyun Chul Koh

Food and Chemical Toxicology, 2020, 137, 111163
DOI: 10.1016/j.fct.2020.111163

Epsilon Toxin from Clostridium perfringens Causes Inhibition of Potassium inward Rectifier (Kir) Channels in Oligodendrocytes

Jean Louis Bossu, Laetitia Wioland, Frédéric Doussau, Philippe Isope, Michel R. Popoff and Bernard Poulain

Toxins, 2020, 12, 36
DOI: 10.3390/toxins12010036

Vibrio parahaemolyticus thermostable direct haemolysin induces non‐classical programmed cell death despite caspase activation

Pratima Verma, Aakanksha Chauhan, Reena Thakur, Kusum Lata, Arpita Sharma, Kausik Chattopadhyay and Arunika Mukhopadhaya

Molecular Microbiology, 2023, 120, 845
DOI: 10.1111/mmi.15180

Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

Irene Wuethrich, Janneke G. C. Peeters, Annet E. M. Blom, Christopher S. Theile, Zeyang Li, Eric Spooner, Hidde L. Ploegh, Carla P. Guimaraes and Ludger Johannes

PLoS ONE, 2014, 9, e109883
DOI: 10.1371/journal.pone.0109883

Mechanisms protecting host cells against bacterial pore-forming toxins

Cláudia Brito, Didier Cabanes, Francisco Sarmento Mesquita and Sandra Sousa

Cell. Mol. Life Sci., 2019, 76, 1319
DOI: 10.1007/s00018-018-2992-8

Pore-forming toxins in infection and immunity

Pratima Verma, Shraddha Gandhi, Kusum Lata and Kausik Chattopadhyay

Biochemical Society Transactions, 2021, 49, 455
DOI: 10.1042/BST20200836