A bioconjugated MoS2 based nanoplatform with increased binding efficiency to cancer cells

Anna Kálosi, Martina Labudová, Adriana Annušová, Monika Benkovičová, Michal Bodík, Jozef Kollár, Mário Kotlár, Peter Kasak, Matej Jergel, Silvia Pastoreková, Peter Siffalovic and Eva Majkova

Biomater. Sci., 2020, 8, 1973
DOI: 10.1039/C9BM01975H

Exploring the in vitro potential of royal jelly against glioblastoma and neuroblastoma: impact on cell proliferation, apoptosis, cell cycle, and the biomolecular content

Nihal Simsek Ozek

Analyst, 2024, 149, 1872
DOI: 10.1039/D3AN01840G

Exploiting fourier transform infrared and Raman microspectroscopies on cancer stem cells from oral squamous cells carcinoma: new evidence of acquired cisplatin chemoresistance

Valentina Notarstefano, Simona Sabbatini, Chiara Pro, Alessia Belloni, Giulia Orilisi, Corrado Rubini, Hugh J. Byrne, Lisa Vaccari and Elisabetta Giorgini

Analyst, 2020, 145, 8038
DOI: 10.1039/D0AN01623C

Cellular discrimination using in vitro Raman micro spectroscopy: the role of the nucleolus

Z. Farhane, F. Bonnier, A. Casey, A. Maguire, L. O'Neill and H. J. Byrne

Analyst, 2015, 140, 5908
DOI: 10.1039/C5AN01157D

Multivariate curve Resolution-Alternating least squares coupled with Raman microspectroscopy: new insights into the kinetic response of primary oral squamous carcinoma cells to cisplatin

Valentina Notarstefano, Alessia Belloni, Paolo Mariani, Giulia Orilisi, Giovanna Orsini, Elisabetta Giorgini and Hugh J. Byrne

Analyst, 2023, 148, 4365
DOI: 10.1039/D3AN01182H

Raman spectra-based structural classification analysis of quinoidal and derived molecular systems

Arthur P. Pena, Renata G. Almeida, João Luiz Campos, Hélio F. Dos Santos, Eufrânio N. da Silva Júnior and Ado Jorio

Phys. Chem. Chem. Phys., 2022, 24, 1183
DOI: 10.1039/D1CP04261K

High-content screening Raman spectroscopy (HCS-RS) of panitumumab-exposed colorectal cancer cells

Abdullah S. Mondol, Samir F. El-Mashtoly, Tatjana Frick, Klaus Gerwert, Jürgen Popp and Iwan W. Schie

Analyst, 2019, 144, 6098
DOI: 10.1039/C9AN01176E

Evaluation of Raman spectroscopy for diagnosing EGFR mutation status in lung adenocarcinoma

Lei Wang, Zhipei Zhang, Lijun Huang, Weimiao Li, Qiang Lu, Miaomiao Wen, Ting Guo, Jinhai Fan, Xuejiao Wang, Xinwei Zhang, Jixiang Fang, Xiaolong Yan, Yunfeng Ni and Xiaofei Li

Analyst, 2014, 139, 455
DOI: 10.1039/C3AN01381B

Structural determination of protein-based polymer blends with a promising tool: combination of FTIR and STXM spectroscopic imaging

Shengjie Ling, Zeming Qi, Benjamin Watts, Zhengzhong Shao and Xin Chen

Phys. Chem. Chem. Phys., 2014, 16, 7741
DOI: 10.1039/C4CP00556B

Optimization of Raman-spectrum baseline correction in biological application

Shuxia Guo, Thomas Bocklitz and Jürgen Popp

Analyst, 2016, 141, 2396
DOI: 10.1039/C6AN00041J

A comparative analysis of stem cell differentiation on 2D and 3D substrates using Raman microspectroscopy

F. Ravera, E. Efeoglu and H. J. Byrne

Analyst, 2024, 149, 4041
DOI: 10.1039/D4AN00315B

Monitoring the kinetic evolution of mesenchymal stem cell differentiation using Raman microspectroscopy

F. Ravera, E. Efeoglu and H. J. Byrne

Analyst, 2025, 150, 3445
DOI: 10.1039/D4AN01509F

Ambient electrospray deposition Raman spectroscopy (AESD RS) using soft landed preformed silver nanoparticles for rapid and sensitive analysis

Tripti Ahuja, Atanu Ghosh, Sandip Mondal, Pallab Basuri, Shantha Kumar Jenifer, Pillalamarri Srikrishnarka, Jyoti Sarita Mohanty, Sandeep Bose and Thalappil Pradeep

Analyst, 2019, 144, 7412
DOI: 10.1039/C9AN01700C

Metabolic profiling of murine radiation-induced lung injury with Raman spectroscopy and comparative machine learning

Mitchell Wiebe, Kirsty Milligan, Joan Brewer, Alejandra M. Fuentes, Ramie Ali-Adeeb, Alexandre G. Brolo, Julian J. Lum, Jeffrey L. Andrews, Christina Haston and Andrew Jirasek

Analyst, 2024, 149, 2864
DOI: 10.1039/D4AN00152D

Spectral cross-correlation as a supervised approach for the analysis of complex Raman datasets: the case of nanoparticles in biological cells

Mark E. Keating, Franck Bonnier and Hugh J. Byrne

Analyst, 2012, 137, 5792
DOI: 10.1039/c2an36169h

New insights of Raman spectroscopy for oral clinical applications

Luis Felipe das Chagas e Silva de Carvalho and Marcelo Saito Nogueira

Analyst, 2018, 143, 6037
DOI: 10.1039/C8AN01363B

Identifying and localizing intracellular nanoparticles using Raman spectroscopy

Jennifer Dorney, Franck Bonnier, Amaya Garcia, Alan Casey, Gordon Chambers and Hugh J. Byrne

Analyst, 2012, 137, 1111
DOI: 10.1039/c2an15977e

Monitoring stem cell differentiation using Raman microspectroscopy: chondrogenic differentiation, towards cartilage formation

Francesca Ravera, Esen Efeoglu and Hugh J. Byrne

Analyst, 2021, 146, 322
DOI: 10.1039/D0AN01983F

Raman micro spectroscopy for in vitro drug screening: subcellular localisation and interactions of doxorubicin

Z. Farhane, F. Bonnier, A. Casey and H. J. Byrne

Analyst, 2015, 140, 4212
DOI: 10.1039/C5AN00256G

Machine learning enabling high-throughput and remote operations at large-scale user facilities

Tatiana Konstantinova, Phillip M. Maffettone, Bruce Ravel, Stuart I. Campbell, Andi M. Barbour and Daniel Olds

Digital Discovery, 2022, 1, 413
DOI: 10.1039/D2DD00014H

Applications of Raman spectroscopy in the development of cell therapies: state of the art and future perspectives

Shreyas Rangan, H. Georg Schulze, Martha Z. Vardaki, Michael W. Blades, James M. Piret and Robin F. B. Turner

Analyst, 2020, 145, 2070
DOI: 10.1039/C9AN01811E

Raman classification of selected subtypes of acute lymphoblastic leukemia (ALL)

Adriana Adamczyk, Anna M. Nowakowska, Justyna Jakubowska, Marta Zabczynska, Maja Bartoszek, Sviatlana Kashyrskaya, Agnieszka Fatla, Kacper Stawoski, Kacper Siakala, Agata Pastorczak, Kinga Ostrowska, Wojciech Mlynarski, Katarzyna Majzner and Malgorzata Baranska

Analyst, 2024, 149, 571
DOI: 10.1039/D3AN01708G

Collagen formation observed from healing calvarial defects with principal component analysis of Raman scattering

Rafay Ahmed, Wenhao Wang, Abdul Wasy Zia and Condon Lau

Analyst, 2018, 143, 4614
DOI: 10.1039/C8AN01021H

Raman and infra-red microspectroscopy: towards quantitative evaluation for clinical research by ratiometric analysis

Srividya Kumar, Taru Verma, Ria Mukherjee, Freek Ariese, Kumaravel Somasundaram and Siva Umapathy

Chem. Soc. Rev., 2016, 45, 1879
DOI: 10.1039/C5CS00540J

Detecting antimicrobial resistance in Escherichia coli using benchtop attenuated total reflectance-Fourier transform infrared spectroscopy and machine learning

Hewa G. S. Wijesinghe, Dominic J. Hare, Ahmed Mohamed, Alok K. Shah, Patrick N. A. Harris and Michelle M. Hill

Analyst, 2021, 146, 6211
DOI: 10.1039/D1AN00546D

Spectral pre and post processing for infrared and Raman spectroscopy of biological tissues and cells

Hugh J. Byrne, Peter Knief, Mark E. Keating and Franck Bonnier

Chem. Soc. Rev., 2016, 45, 1865
DOI: 10.1039/C5CS00440C

Processing ThinPrep cervical cytological samples for Raman spectroscopic analysis

Franck Bonnier, Damien Traynor, Padraig Kearney, Colin Clarke, Peter Knief, Cara Martin, John J. O'Leary, Hugh J. Byrne and Fiona Lyng

Anal. Methods, 2014, 6, 7831
DOI: 10.1039/C4AY01497A

Probing metabolic alterations in breast cancer in response to molecular inhibitors with Raman spectroscopy and validated with mass spectrometry

Xiaona Wen, Yu-Chuan Ou, Galina Bogatcheva, Giju Thomas, Anita Mahadevan-Jansen, Bhuminder Singh, Eugene C. Lin and Rizia Bardhan

Chem. Sci., 2020, 11, 9863
DOI: 10.1039/D0SC02221G

Determination of phase behaviour in all protein blend materials with multivariate FTIR imaging technique

Shengjie Ling, Zeming Qi, Zhengzhong Shao and Xin Chen

J. Mater. Chem. B, 2015, 3, 834
DOI: 10.1039/C4TB01808G

Challenges in application of Raman spectroscopy to biology and materials

Nikki Kuhar, Sanchita Sil, Taru Verma and Siva Umapathy

RSC Adv., 2018, 8, 25888
DOI: 10.1039/C8RA04491K

Quantification of low-content encapsulated active cosmetic ingredients in complex semi-solid formulations by means of attenuated total reflectance-infrared spectroscopy

Franck Bonnier, Lynda Miloudi, Sandra Henry, Dominique Bertrand, Clovis Tauber, Xavier Perse, Florent Yvergnaux, Hugh J. Byrne, Igor Chourpa and Emilie Munnier

Anal Bioanal Chem, 2020, 412, 159
DOI: 10.1007/s00216-019-02221-2

Differentiation of Salivary Gland and Salivary Gland Tumor Tissue via Raman Imaging Combined with Multivariate Data Analysis

Miriam Bassler, Mona Knoblich, Elena Gerhard-Hartmann, Ashutosh Mukherjee, Almoatazbellah Youssef, Rudolf Hagen, Lukas Haug, Miguel Goncalves, Agmal Scherzad, Manuel Stöth, Edwin Ostertag, Maria Steinke, Marc Brecht, Stephan Hackenberg and Till Meyer

Diagnostics, 2023, 14, 92
DOI: 10.3390/diagnostics14010092

Direct Readout of Homo- vs Heterochiral Ligand Shell of Quantum Dots

Elżbieta Chwojnowska, Aneta A. Kowalska, Agnieszka Kamińska and Janusz Lewiński

ACS Appl. Mater. Interfaces, 2024, 16, 37308
DOI: 10.1021/acsami.4c07648

Prediction of viral loads for diagnosis of Hepatitis C infection in human plasma samples using Raman spectroscopy coupled with partial least squares regression analysis

H. Nawaz, N. Rashid, M. Saleem, M. Asif Hanif, M. Irfan Majeed, I. Amin, M. Iqbal, M. Rahman, Ola Ibrahim, S. M. Baig, M. Ahmed, F. Bonnier and H. J. Byrne

J Raman Spectroscopy, 2017, 48, 697
DOI: 10.1002/jrs.5108

Multivariate Analysis for the Processing of Signals

J.R. Beattie

Oil Gas Sci. Technol. – Rev. IFP Energies nouvelles, 2014, 69, 207
DOI: 10.2516/ogst/2013185

Micro-Raman spectroscopic study of thyroid tissues

Lázaro Pinto Medeiros Neto, Luis Felipe das Chagas e Silva de Carvalho, Laurita dos Santos, Cláudio Alberto Tellez Soto, Renata de Azevedo Canevari, André Bandiera de Oliveira Santos, Evandro Sobroza Mello, Marina Aparecida Pereira, Cláudio Roberto Cernea, Lenine Garcia Brandão and Aírton Abrahão Martin

Photodiagnosis and Photodynamic Therapy, 2017, 17, 164
DOI: 10.1016/j.pdpdt.2016.11.018

Non-invasive Monitoring of Biochemical Response of Wheat Seedlings Toward Titanium Dioxide Nanoparticles Treatment Using Attenuated Total Reflectance Fourier Transform Infrared and Laser Induced Fluorescence Spectroscopy

Sweta Sharma and K. N. Uttam

Analytical Letters, 2019, 52, 1629
DOI: 10.1080/00032719.2018.1563940

TemporalIn VitroRaman Spectroscopy for Monitoring Replication Kinetics of Epstein–Barr Virus Infection in Glial Cells

Deeksha Tiwari, Shweta Jakhmola, Devesh K. Pathak, Rajesh Kumar and Hem Chandra Jha

ACS Omega, 2020, 5, 29547
DOI: 10.1021/acsomega.0c04525

Preeclampsia Correlates with an Increase in Cannabinoid Receptor 1 Levels Leading to Macromolecular Alterations in Chorionic Villi of Term Placenta

Marta Lombó, Christian Giommi, Michela Paolucci, Valentina Notarstefano, Nina Montik, Giovanni Delli Carpini, Andrea Ciavattini, Antonio Ragusa, Francesca Maradonna, Elisabetta Giorgini and Oliana Carnevali

IJMS, 2022, 23, 12931
DOI: 10.3390/ijms232112931

Raman Spectroscopy of Carotenoid Compounds for Clinical Applications—A Review

Joy Udensi, James Loughman, Ekaterina Loskutova and Hugh J. Byrne

Molecules, 2022, 27, 9017
DOI: 10.3390/molecules27249017

Raman spectroscopic analysis of human blood serum of glaucoma patients supplemented with macular pigment carotenoids

Joy Udensi, Ekaterina Loskutova, James Loughman and Hugh J. Byrne

Journal of Biophotonics, 2024, 17
DOI: 10.1002/jbio.202400060

Phenotypic responses in Caenorhabditis elegans following chronic low-level exposures to inorganic and organic compounds

Fidelis Mugova, Daniel S. Read, Matthew J. Riding, Francis L. Martin, William Tyne, Claus Svendsen and David Spurgeon

Environmental Toxicology and Chemistry, 2017, 37, 920
DOI: 10.1002/etc.4026

Raman spectroscopy and its plasmon‐enhanced counterparts: A toolbox to probe protein dynamics and aggregation

Ashish Kumar Dhillon, Arti Sharma, Vikas Yadav, Ruchi Singh, Tripti Ahuja, Sanmitra Barman and Soumik Siddhanta

WIREs Nanomed Nanobiotechnol, 2024, 16
DOI: 10.1002/wnan.1917

Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy

Mengmeng Liu, Xiujie Liu, Zufang Huang, Xiaoqiong Tang, Xueliang Lin, Yunchao Xu, Guannan Chen, Hang Fai Kwok, Yao Lin and Shangyuan Feng

Journal of Biophotonics, 2019, 12
DOI: 10.1002/jbio.201800332

Raman spectroscopy and supervised learning as a potential tool to identify high‐dose‐rate‐brachytherapy induced biochemical profiles of prostate cancer

Kirsty Milligan, Samantha J. Van Nest, Xinchen Deng, Ramie Ali‐Adeeb, Phillip Shreeves, Samantha Punch, Nathalie Costie, Nils Pavey, Juanita M. Crook, David M. Berman, Alexandre G. Brolo, Julian J. Lum, Jeffrey L. Andrews and Andrew Jirasek

Journal of Biophotonics, 2022, 15
DOI: 10.1002/jbio.202200121

Label-Free Evaluation of Osteogenic Differentiation Using Extended-Focus Raman Imaging

Heqi Xi, Phan Bhongsatiern, Menglu Li, Tomoaki Iwayama, Masahide Takedachi, Yoshinori Yamaguchi and Katsumasa Fujita

Anal. Chem., 2025, 97, 21218
DOI: 10.1021/acs.analchem.5c00921

Raman Spectroscopy in Prostate Cancer: Techniques, Applications and Advancements

Fortis Gaba, William J. Tipping, Mark Salji, Karen Faulds, Duncan Graham and Hing Y. Leung

Cancers, 2022, 14, 1535
DOI: 10.3390/cancers14061535

The structural effects of Vitamin A deficiency on biological macromolecules due to ethanol consumption and withdrawal: An FTIR study with chemometrics

Birsen Elibol, Mete Severcan, Ewa Jakubowska‐Dogru, Ilknur Dursun and Feride Severcan

Journal of Biophotonics, 2022, 15
DOI: 10.1002/jbio.202100377

Label-Free Imaging of Lipid Droplets in Prostate Cells Using Stimulated Raman Scattering Microscopy and Multivariate Analysis

Ewan W. Hislop, William J. Tipping, Karen Faulds and Duncan Graham

Anal. Chem., 2022, 94, 8899
DOI: 10.1021/acs.analchem.2c00236

Raman spectroscopy in biomedicine – non‐invasive in vitro analysis of cells and extracellular matrix components in tissues

Eva Brauchle and Katja Schenke‐Layland

Biotechnology Journal, 2013, 8, 288
DOI: 10.1002/biot.201200163

A Comparison of PCA-LDA and PLS-DA Techniques for Classification of Vibrational Spectra

Maria Lasalvia, Vito Capozzi and Giuseppe Perna

Applied Sciences, 2022, 12, 5345
DOI: 10.3390/app12115345

An in vitro study of the interaction of the chemotherapeutic drug Actinomycin D with lung cancer cell lines using Raman micro‐spectroscopy

Zeineb Farhane, Franck Bonnier and Hugh J. Byrne

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700112

Ethnic hair: Thermoanalytical and spectroscopic differences

Marc A. Oliver, Luisa Coderch, Victor Carrer, Clara Barba and Meritxell Marti

Skin Research and Technology, 2020, 26, 617
DOI: 10.1111/srt.12842

DeltaPCA: A statistically robust method for analysing surface-enhanced Raman spectra for quantitative analyte detection

Fiona M. Given, Tamsyn Stanborough, Mark R. Waterland and Deborah L. Crittenden

Vibrational Spectroscopy, 2022, 121, 103389
DOI: 10.1016/j.vibspec.2022.103389

Fourier transform infrared spectroscopy coupled with machine learning classification for identification of oxidative damage in freeze-dried heart valves

Dejia Liu, Sükrü Caliskan, Bita Rashidfarokhi, Harriëtte Oldenhof, Klaus Jung, Harald Sieme, Andres Hilfiker and Willem F. Wolkers

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-91802-2

Saliva protein profiling for subject identification and potential medical applications

Christy Thomas and Cecilia Giulivi

Medicine in Omics, 2021, 3, 100012
DOI: 10.1016/j.meomic.2021.100012

Raman spectroscopic analysis of human serum samples of convalescing COVID-19 positive patients

Naomi Jackson, Jaythoon Hassan and Hugh J. Byrne

Clinical Spectroscopy, 2023, 5, 100028
DOI: 10.1016/j.clispe.2023.100028

Diagnostic strategy for malignant and benign thyroid nodules smaller than 10 mm based on surface-enhanced Raman spectroscopy and machine learning

Xiao Liu, Meihuan Wang, Kaining Zhang, Huawei Zhang and Yongchao Lai

Chemical Engineering Journal, 2023, 471, 144794
DOI: 10.1016/j.cej.2023.144794

NWU‐RSIT: An integrated graphical user interface for biomedical Raman spectral imaging with both univariate and multivariate modules

Yishen Chen, Jie Li, Dongliang Song, Jie Qin, Haifeng Wang, Tian Ning and Shuang Wang

J Raman Spectroscopy, 2021, 52, 1428
DOI: 10.1002/jrs.6177

SERS-based DNA methylation profiling allows the differential diagnosis of malignant lymphadenopathy

Andrei Stefancu, Vlad Moisoiu, Minodora Desmirean, Stefania D. Iancu, Adrian B. Tigu, Bobe Petrushev, Ancuta Jurj, Ramona G. Cozan, Liviuta Budisan, Bogdan Fetica, Andrei Roman, Gina Dobie, Cristina Turcas, Mihnea Zdrenghea, Patric Teodorescu, Sergiu Pasca, Doina Piciu, Delia Dima, Zoltán Bálint, Nicolae Leopold and Ciprian Tomuleasa

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 264, 120216
DOI: 10.1016/j.saa.2021.120216

Surface Enhanced Raman Spectroscopy for Single Molecule Protein Detection

Lamyaa M. Almehmadi, Stephanie M. Curley, Natalya A. Tokranova, Scott A. Tenenbaum and Igor K. Lednev

Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-48650-y

Label-Free Quantification of Nanoencapsulated Piperonyl Esters in Cosmetic Hydrogels Using Raman Spectroscopy

Suha Elderderi, Franck Bonnier, Xavier Perse, Hugh J. Byrne, Florent Yvergnaux, Igor Chourpa, Abdalla A. Elbashir and Emilie Munnier

Pharmaceutics, 2023, 15, 1571
DOI: 10.3390/pharmaceutics15061571

Biochemical impact of solar radiation exposure on human keratinocytes monitored by Raman spectroscopy; effects of cell culture environment

Ulises Lopez‐Gonzalez, Alan Casey and Hugh J. Byrne

Journal of Biophotonics, 2021, 14
DOI: 10.1002/jbio.202100058

Synovial fluid research based on SERS and SERRS for enhanced detection of biomarkers in staged osteoarthritis

Jinjin Wu, Jiachun Dong, Yilin Bao, Linwei Shang, Qingxia Wu, Zichun Yang, Huijie Wang and Jianhua Yin

Journal of Biophotonics, 2024, 17
DOI: 10.1002/jbio.202400024

Confocal Raman spectroscopic imaging for in vitro monitoring of active ingredient penetration and distribution in reconstructed human epidermis model

Lynda Miloudi, Franck Bonnier, Ali Tfayli, Florent Yvergnaux, Hugh J. Byrne, Igor Chourpa and Emilie Munnier

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700221

Diagnosis of normal and malignant human gastric tissue samples by FTIR spectra combined with mathematical models

Maryam Ghassemi K, Sahar Barzegari, Parastoo Hajian, Hanieh Zham, Hamid Reza Mirzaei and Farshad H. Shirazi

Journal of Molecular Structure, 2021, 1229, 129493
DOI: 10.1016/j.molstruc.2020.129493

ATR-FTIR spectroscopy combined with chemometrics reveals molecular alterations and anticancer effects of Nigella sativa extract in human colon cancer cells

Nihal Simsek Ozek, Ipek Ozyurt, Fulya Kucukcankurt, Huseyin Servi and Feride Severcan

Sci Rep, 2026, 16
DOI: 10.1038/s41598-026-34994-9

Raman micro-spectroscopy analysis of different sperm regions: a species comparison

S Amaral, R Da Costa, F Wübbeling, K Redmann and S Schlatt

MHR: Basic science of reproductive medicine, 2018, 24, 185
DOI: 10.1093/molehr/gax071

SERS-based liquid biopsy of saliva and serum from patients with Sjögren’s syndrome

Andrei Stefancu, Maria Badarinza, Vlad Moisoiu, Stefania D. Iancu, Oana Serban, Nicolae Leopold and Daniela Fodor

Anal Bioanal Chem, 2019, 411, 5877
DOI: 10.1007/s00216-019-01969-x

An Interpretable SERS–AI Platform for Rapid and Quantitative Diagnosis of Polymicrobial UTIs: Powered by Positively Charged Plasmonic Nanoparticles and Attention‐Based Deep Learning

Zhonghua Shen, Linguo Xie, Yuwei Hou, Junjie Liang, Yuchi Jia, Haipeng Zhang, Zhenli Sun, Jingjing Du, Zeying He, Chunyu Liu and Wenjing Liu

Advanced Science, 2025, 12
DOI: 10.1002/advs.202513502

Chemometrics-aided surface-enhanced Raman spectrometric detection and quantification of GH and TE hormones in blood

Annah M. Ondieki, Zephania Birech, Kenneth A. Kaduki, Peter W. Mwangi, Moses Juma, Boniface M. Chege and Tanveer A. Tabish

PLoS One, 2025, 20, e0323697
DOI: 10.1371/journal.pone.0323697

Rapid and noninvasive diagnosis of oral and oropharyngeal cancer based on micro-Raman and FT-IR spectra of saliva

A. Falamas, C.I. Faur, S. Ciupe, M. Chirila, H. Rotaru, M. Hedesiu and S. Cinta Pinzaru

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 252, 119477
DOI: 10.1016/j.saa.2021.119477

Monitoring doxorubicin cellular uptake and trafficking using in vitro Raman microspectroscopy: short and long time exposure effects on lung cancer cell lines

Zeineb Farhane, Franck Bonnier and Hugh J. Byrne

Anal Bioanal Chem, 2017, 409, 1333
DOI: 10.1007/s00216-016-0065-0

Characterization of Distinct Chondrogenic Cell Populations of Patients Suffering from Microtia Using Single-Cell Micro-Raman Spectroscopy

Dominika Zielinska, Hesham K. Yosef, Tilo Zollitsch, Johann Kern, Yvonne Jakob, David Gvaramia, Nicole Rotter, Luca Pontiggia, Ueli Moehrlen, Thomas Biedermann and Agnes S. Klar

Biomedicines, 2023, 11, 2588
DOI: 10.3390/biomedicines11092588

Combining Multiple Spectroscopic Techniques to Reveal the Effects of Staphylococcus aureus Infection on Human Bone Tissues

Martina Alunni Cardinali, Marco Govoni, Sara Stefani, Alessandra Maso, Elisa Storni, Francesca Valenti, Melania Maglio, Assunta Morresi, Daniele Fioretto, Dante Dallari and Paola Sassi

Appl Spectrosc, 2024, 78, 1295
DOI: 10.1177/00037028241278903

Aligned nanofibrous collagen membranes from fish swim bladder as a tough and acid-resistant suture for pH-regulated stomach perforation and tendon rupture

Zhaohui Luan, Shuang Liu, Wei Wang, Kaige Xu, Shaosong Ye, Ruijue Dan, Hong Zhang, Zhenzhen Shu, Tongchuan Wang, Chaoqiang Fan, Malcolm Xing and Shiming Yang

Biomater Res, 2022, 26
DOI: 10.1186/s40824-022-00306-1

Discrimination of Different Breast Cell Lines on Glass Substrate by Means of Fourier Transform Infrared Spectroscopy

Maria Lasalvia, Vito Capozzi and Giuseppe Perna

Sensors, 2021, 21, 6992
DOI: 10.3390/s21216992

Spectralomics – Towards a holistic adaptation of label free spectroscopy

Hugh J. Byrne

Vibrational Spectroscopy, 2024, 132, 103671
DOI: 10.1016/j.vibspec.2024.103671

Raman micro-spectroscopy for rapid screening of oral squamous cell carcinoma

Luis Felipe C.S. Carvalho, Franck Bonnier, Kate O'Callaghan, Jeff O'Sullivan, Stephen Flint, Hugh J. Byrne and Fiona M. Lyng

Experimental and Molecular Pathology, 2015, 98, 502
DOI: 10.1016/j.yexmp.2015.03.027

Gestational Diabetes Mellitus and Small-for-Gestational-Age: An Insight into the Placental Molecular Biomarkers

Christian Giommi, Marta Lombό, Nina Montik, Michela Paolucci, Valentina Notarstefano, Giovanni Delli Carpini, Andrea Ciavattini, Antonio Ragusa, Francesca Maradonna, Elisabetta Giorgini and Oliana Carnevali

IJMS, 2023, 24, 2240
DOI: 10.3390/ijms24032240

Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue

Nosheen Rashid, Haq Nawaz, Kelvin W.C. Poon, Franck Bonnier, Salih Bakhiet, Cara Martin, John J. O'Leary, Hugh J. Byrne and Fiona M. Lyng

Experimental and Molecular Pathology, 2014, 97, 554
DOI: 10.1016/j.yexmp.2014.10.013

Linking ATR-FTIR and Raman features to phenolic extractability and other attributes in grape skin

Julio Nogales-Bueno, Berta Baca-Bocanegra, Abigail Rooney, José Miguel Hernández-Hierro, Francisco José Heredia and Hugh J. Byrne

Talanta, 2017, 167, 44
DOI: 10.1016/j.talanta.2017.02.008

Meso-Raman approach for rapid yeast cells identification

Martina Alunni Cardinali, Debora Casagrande Pierantoni, Silvia Caponi, Laura Corte, Daniele Fioretto and Gianluigi Cardinali

Biophysical Chemistry, 2019, 254, 106249
DOI: 10.1016/j.bpc.2019.106249

Raman spectral post-processing for oral tissue discrimination – a step for an automatized diagnostic system

Luis Felipe C. S. Carvalho, Marcelo Saito Nogueira, Lázaro P. M. Neto, Tanmoy T. Bhattacharjee and Airton A. Martin

Biomed. Opt. Express, 2017, 8, 5218
DOI: 10.1364/BOE.8.005218

Royal Jelly's Strong Selective Cytotoxicity Against Lung Malignant Cells and Macromolecular Alterations in Cells Observed by FTIR Spectroscopy

ferhunde Aysin

ACAMC, 2025, 25, 750
DOI: 10.2174/0118715206355400241112084611

PCANet: A Common Solution for Laser-Induced Fluorescence Spectral Classification

Feng Hu, Mengran Zhou, Pengcheng Yan, Kai Bian and Rongying Dai

IEEE Access, 2019, 7, 107129
DOI: 10.1109/ACCESS.2019.2933453

Qualitative and quantitative analysis of therapeutic solutions using Raman and infrared spectroscopy

Alaa A. Makki, Franck Bonnier, Renaud Respaud, Fatma Chtara, Ali Tfayli, Clovis Tauber, Dominique Bertrand, Hugh J. Byrne, Elhadi Mohammed and Igor Chourpa

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 218, 97
DOI: 10.1016/j.saa.2019.03.056

Adaptive mechanism of the marine bacterium Pseudomonas sihuiensis-BFB-6S towards pCO2 variation: Insights into synthesis of extracellular polymeric substances and physiochemical modulation

Subham Chakraborty, Murali Krishna Paidi, Inbakandan Dhinakarasamy, Manikandan Sivakumar, Clarita Clements, Naren Kumar Thirumurugan and Lakshminarayanan Sivakumar

International Journal of Biological Macromolecules, 2024, 261, 129860
DOI: 10.1016/j.ijbiomac.2024.129860

Label‐free Raman spectroscopic imaging to extract morphological and chemical information from a formalin‐fixed, paraffin‐embedded rat colon tissue section

Riana Gaifulina, Andrew Thomas Maher, Catherine Kendall, James Nelson, Manuel Rodriguez‐Justo, Katherine Lau and Geraint Mark Thomas

Int J Experimental Path, 2016, 97, 337
DOI: 10.1111/iep.12194

In vitro Label Free Raman Microspectroscopic Analysis to Monitor the Uptake, Fate and Impacts of Nanoparticle Based Materials

Hugh J. Byrne, Franck Bonnier, Esen Efeoglu, Caroline Moore and Jennifer McIntyre

Front. Bioeng. Biotechnol., 2020, 8
DOI: 10.3389/fbioe.2020.544311

Lipid loses and barrier function modifications of the brown‐to‐white hair transition

Marc A. Oliver, Meritxell Marti, Luisa Coderch, Victor Carrer, Martin Kreuzer and Clara Barba

Skin Research and Technology, 2019, 25, 517
DOI: 10.1111/srt.12681

Molecular-level changes induced by hydroxycinnamic acid derivatives in HepG2 cell line: Comparison with pravastatin

Asma Ressaissi, Rita Pacheco and Maria Luísa M. Serralheiro

Life Sciences, 2021, 283, 119846
DOI: 10.1016/j.lfs.2021.119846

Screening the low molecular weight fraction of human serum using ATR-IR spectroscopy

Franck Bonnier, Guillaume Brachet, Romain Duong, Tobiloba Sojinrin, Renaud Respaud, Nicolas Aubrey, Matthew J. Baker, Hugh J. Byrne and Igor Chourpa

J. Biophoton, 2016, 9, 1085
DOI: 10.1002/jbio.201600015

Spectral fingerprinting to evaluate effects of storage conditions on biomolecular structure of filter-dried saliva samples and recovered DNA

Raffaele Brogna, Harriëtte Oldenhof, Harald Sieme and Willem F. Wolkers

Sci Rep, 2020, 10
DOI: 10.1038/s41598-020-78306-1

Polystyrene nanoplastics diminish the toxic effects of Nano-TiO2 in marine algae Chlorella sp.

Lokeshwari Natarajan, M. Annie Jenifer, N. Chandrasekaran, G.K. Suraishkumar and Amitava Mukherjee

Environmental Research, 2022, 204, 112400
DOI: 10.1016/j.envres.2021.112400

Garlic bulb classification by combining Raman spectroscopy and machine learning

Zhixin Wang, Chenming Li, Zhong Wang, Yuee Li and Bin Hu

Vibrational Spectroscopy, 2023, 125, 103509
DOI: 10.1016/j.vibspec.2023.103509

FTIR Spectroscopy of Vitreous Humor for Postmortem Interval Estimation: A Multivariate Regression Approach

Ioana Ruxandra Țurlea, George Cristian Curca, Maria Mernea, Alina Cristina Mătanie, Sergiu Fendrihan and Dan Florin Mihăilescu

IJMS, 2026, 27, 3468
DOI: 10.3390/ijms27083468

In vitro label‐free screening of chemotherapeutic drugs using Raman microspectroscopy: Towards a new paradigm of spectralomics

Zeineb Farhane, Haq Nawaz, Franck Bonnier and Hugh J. Byrne

Journal of Biophotonics, 2018, 11
DOI: 10.1002/jbio.201700258

Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging

Ruben Daum, Eva M. Brauchle, Daniel Alejandro Carvajal Berrio, Tomasz P. Jurkowski and Katja Schenke-Layland

Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-43520-z

Raman Analysis of Tear Fluid Alteration Following Contact Lense Use

Angela Capaccio, Antonio Sasso and Giulia Rusciano

Sensors, 2019, 19, 3392
DOI: 10.3390/s19153392

Advances in Biomedical Applications of Raman Microscopy and Data Processing: A Mini Review

Ram Krishna and Ilhami Colak

Analytical Letters, 2023, 56, 576
DOI: 10.1080/00032719.2022.2094391

Optical diagnosis of hepatitis B virus infection in blood plasma using Raman spectroscopy and chemometric techniques

M. Saleem, Safdar Ali, M. Bilal Khan, Ayyaz Amin, M. Bilal, Haq Nawaz and Mehdi Hassan

J Raman Spectroscopy, 2020, 51, 1067
DOI: 10.1002/jrs.5896

Raman Spectroscopy of Biological Tissues

Abdullah Chandra Sekhar Talari, Zanyar Movasaghi, Shazza Rehman and Ihtesham ur Rehman

Applied Spectroscopy Reviews, 2015, 50, 46
DOI: 10.1080/05704928.2014.923902

Biochemical changes in the cytoplasm of bovine oocytes during the in vitro maturation process: a Raman microscopy study

Luis Emanuel Jimenez, Ana Carolina Juárez, Mariela Roldán-Olarte and Rosa María Susana Álvarez

Vet Res Commun, 2022, 46, 549
DOI: 10.1007/s11259-021-09882-4

Raman spectroscopy combined with multivariate statistical algorithms for the simultaneous screening of cervical and breast cancers

Yue Cao, Jiaran Xiong, Yu Du, Yishu Tang and Longfei Yin

Lasers Med Sci, 2024, 39
DOI: 10.1007/s10103-024-04019-w

RSPSSL: A novel high-fidelity Raman spectral preprocessing scheme to enhance biomedical applications and chemical resolution visualization

Jiaqi Hu, Gina Jinna Chen, Chenlong Xue, Pei Liang, Yanqun Xiang, Chuanlun Zhang, Xiaokeng Chi, Guoying Liu, Yanfang Ye, Dongyu Cui, De Zhang, Xiaojun yu, Hong Dang, Wen Zhang, Junfan Chen, Quan Tang, Penglai Guo, Ho-Pui Ho, Yuchao Li, Longqing Cong and Perry Ping Shum

Light Sci Appl, 2024, 13
DOI: 10.1038/s41377-024-01394-5

Methods and Applications of Raman Microspectroscopy to Single-Cell Analysis

Iwan W. Schie and Thomas Huser

Appl Spectrosc, 2013, 67, 813
DOI: 10.1366/12-06971

Nail Raman spectroscopy: A promising method for the diagnosis of onychomycosis. An ex vivo pilot study

Nikolaos Kourkoumelis, Georgios Gaitanis, Aristea Velegraki and Ioannis D Bassukas

Medical Mycology, 2018, 56, 551
DOI: 10.1093/mmy/myx078

Saliva based non invasive screening of Oral Submucous Fibrosis using ATR-FTIR spectroscopy

Shayma Shaikh, Deep Kumari Yadav and Rakesh Rawal

Journal of Pharmaceutical and Biomedical Analysis, 2021, 203, 114202
DOI: 10.1016/j.jpba.2021.114202

Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy

Eva Brauchle, Sibylle Thude, Sara Y. Brucker and Katja Schenke-Layland

Sci Rep, 2014, 4
DOI: 10.1038/srep04698

Influence of Protein Size on Surface-Enhanced Raman Scattering (SERS) Spectra in Binary Protein Mixtures

Ertug Avci and Mustafa Culha

Appl Spectrosc, 2014, 68, 890
DOI: 10.1366/13-07445

Raman spectroscopy and group and basis-restricted non negative matrix factorisation identifies radiation induced metabolic changes in human cancer cells

Kirsty Milligan, Xinchen Deng, Phillip Shreeves, Ramie Ali-Adeeb, Quinn Matthews, Alexandre Brolo, Julian J. Lum, Jeffrey L. Andrews and Andrew Jirasek

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-83343-5

Raman Microspectral Study and Classification of the Pathological Evolution of Breast Cancer Using Both Principal Component Analysis-Linear Discriminant Analysis and Principal Component Analysis-Support Vector Machine

Heping Li, Yu Ren, Fan Yu, Dongliang Song, Lizhe Zhu, Shibo Yu, Siyuan Jiang, Shuang Wang and Alessandra Durazzo

Journal of Spectroscopy, 2021, 2021, 1
DOI: 10.1155/2021/5572782

Multivariate Analysis of Difference Raman Spectra of the Irradiated Nucleus and Cytoplasm Region of SH-SY5Y Human Neuroblastoma Cells

Ines Delfino, Valerio Ricciardi, Lorenzo Manti, Maria Lasalvia and Maria Lepore

Sensors, 2019, 19, 3971
DOI: 10.3390/s19183971

Detection of Age-Related Changes in Tendon Molecular Composition by Raman Spectroscopy—Potential for Rapid, Non-Invasive Assessment of Susceptibility to Injury

Nai-Hao Yin, Anthony W. Parker, Pavel Matousek and Helen L. Birch

IJMS, 2020, 21, 2150
DOI: 10.3390/ijms21062150

Compositional and structural characterization of dorsal root ganglion neurons and co-cultured Schwann cells by confocal Raman microspectral imaging

Jie Li

Vibrational Spectroscopy, 2024, 130, 103642
DOI: 10.1016/j.vibspec.2023.103642

Monitoring the biochemical changes occurring to human keratinocytes exposed to solar radiation by Raman spectroscopy

Ulises Lopez‐Gonzalez, Alan Casey and Hugh J. Byrne

Journal of Biophotonics, 2021, 14
DOI: 10.1002/jbio.202000337

Cancer detection in dogs using rapid Raman molecular urinalysis

John L. Robertson, Nikolas Dervisis, John Rossmeisl, Marlie Nightengale, Daniel Fields, Cameron Dedrick, Lacey Ngo, Amr Sayed Issa, Georgi Guruli, Giuseppe Orlando and Ryan S. Senger

Front. Vet. Sci., 2024, 11
DOI: 10.3389/fvets.2024.1328058

Maria Lasalvia, Giuseppe Perna and Vito Capozzi

Applied Sciences, 2019, 9, 3700
DOI: 10.3390/app9183700

Spectral features of nuclear DNA in human sperm assessed by Raman Microspectroscopy: Effects of UV-irradiation and hydration

Raul Da Costa, Sandra Amaral, Klaus Redmann, Sabine Kliesch, Stefan Schlatt and Shree Ram Singh

PLoS ONE, 2018, 13, e0207786
DOI: 10.1371/journal.pone.0207786

In situ semi-quantitative imaging of intracellular metabolic interaction by confocal Raman microscopy

Wanying He, Minxiao Wang, Zhaoshan Zhong, Hao Chen, Shichuan Xi, Huan Zhang, Mengna Li, Wenhao Sun, Yan Zhang, Yun Wang, Xiaoxiao Guo, Lianfu Li, Zengfeng Du, Zhendong Luan, Chaolun Li and Xin Zhang

iScience, 2025, 28, 113558
DOI: 10.1016/j.isci.2025.113558

Vibrational Spectroscopy for In Vitro Monitoring Stem Cell Differentiation

Francesca Ravera, Esen Efeoglu and Hugh J. Byrne

Molecules, 2020, 25, 5554
DOI: 10.3390/molecules25235554

Analysis of intra-specific variations in the venom of individual snakes based on Raman spectroscopy

Vera A. Mozhaeva, Vladislav G. Starkov, Denis S. Kudryavtsev, Kirill A. Prokhorov, Sergey V. Garnov and Yuri N. Utkin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 314, 124239
DOI: 10.1016/j.saa.2024.124239

Raman spectroscopic analysis of oral cells in the high wavenumber region

Luis Felipe C.S. Carvalho, Franck Bonnier, Cláudio Tellez, Laurita dos Santos, Kate O'Callaghan, Jeff O'Sullivan, Luis Eduardo S. Soares, Stephen Flint, Airton A. Martin, Fiona M. Lyng and Hugh J. Byrne

Experimental and Molecular Pathology, 2017, 103, 255
DOI: 10.1016/j.yexmp.2017.11.001

Raman Spectroscopy in Nanomedicine: Current Status and Future Perspective

Mark E Keating and Hugh J Byrne

Nanomedicine, 2013, 8, 1335
DOI: 10.2217/nnm.13.108

Real-time Raman analysis of the hydrolysis of formaldehyde oligomers for enhanced collagen fixation

Yansong Wang, Yinlan Ruan, Bobo Du, Ji Li, Heike Ebendorff-Heidepriem and Xuechuan Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 264, 120285
DOI: 10.1016/j.saa.2021.120285

New perspectives for viability studies with high-content analysis Raman spectroscopy (HCA-RS)

Abdullah Saif Mondol, Natalie Töpfer, Jan Rüger, Ute Neugebauer, Jürgen Popp and Iwan W. Schie

Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-48895-7

Simultaneous SERS detection using hexagonal hollow Au-Ag nanoparticles with near infrared plasmon

C.R. Rekha, S.G. Jiji, V.U. Nayar and K.G. Gopchandran

Vibrational Spectroscopy, 2021, 114, 103233
DOI: 10.1016/j.vibspec.2021.103233

Vibrational spectroscopic image analysis of biological material using multivariate curve resolution–alternating least squares (MCR-ALS)

Judith Felten, Hardy Hall, Joaquim Jaumot, Romà Tauler, Anna de Juan and András Gorzsás

Nat Protoc, 2015, 10, 217
DOI: 10.1038/nprot.2015.008

A micro-Raman spectroscopy study of inflammatory condition of human cervix: Probing of tissues and blood plasma samples

Ajaya Kumar Barik, Sanoop Pavithran M, Mithun N, Muralidhar V Pai, Rekha Upadhya, Abhilash K Pai, Jijo Lukose and Santhosh Chidangil

Photodiagnosis and Photodynamic Therapy, 2022, 39, 102948
DOI: 10.1016/j.pdpdt.2022.102948

Gold Nanoparticles SERS in the Nephritis Diagnosis in Lupus Patients from Urine

Alberto Carlos Espinosa, Alejandra Rojo-Sanchez, Ada Carmona-Martes, Natally Vidal-Figueroa, Antony A. Cardozo-Puello, Lisandro Pacheco-Lugo, Elkin Navarro Quiroz, Eloina Zarate-Peñata, Lorena Gómez Escocia, Nataly J. Galán-Freyle, Samuel P. Hernández-Rivera, Joe Villa-Medina, Gustavo Aroca-Martinez, Elvin S. Lebron-Ramirez, Maximiliano Méndez-López and Leonardo C. Pacheco-Londoño

ACS Omega, 2025, 10, 54357
DOI: 10.1021/acsomega.5c06978

Spectroscopic Examination and Chemometric Analysis of Essential Oils Obtained from Peppermint Herb (Mentha piperita L.) and Caraway Fruit (Carum carvi L.) Subjected to Pulsed Electric Fields

Urszula Sadowska, Arkadiusz Matwijczuk, Agnieszka Niemczynowicz, Tomasz Dróżdż and Andrzej Żabiński

Processes, 2019, 7, 466
DOI: 10.3390/pr7070466

A pilot study for early detection of oral premalignant diseases using oral cytology and Raman micro‐spectroscopy: Assessment of confounding factors

Isha Behl, Genecy Calado, Alison Malkin, Stephen Flint, Sheila Galvin, Claire M. Healy, Marina Leite Pimentel, Hugh J. Byrne and Fiona M. Lyng

Journal of Biophotonics, 2020, 13
DOI: 10.1002/jbio.202000079

Heterogeneity of Endothelial Cells Impacts the Functionality of Human Pancreatic In Vitro Models

Max Urbanczyk, Athar Abuhelou, Marie Köninger, Abiramy Jeyagaran, Daniel Carvajal-Berrio, Ellie Kim, Julia Marzi, Peter Loskill, Shannon L. Layland and Katja Schenke-Layland

Tissue Engineering Part A, 2025, 31, 988
DOI: 10.1089/ten.tea.2024.0176

Multimodal Imaging of Silicified Sorghum Leaves

Victor M. R. Zancajo, Sabrina Diehn, Rivka Elbaum and Janina Kneipp

Analysis & Sensing, 2022, 2
DOI: 10.1002/anse.202200006

Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy

Jaakko Itkonen, Leo Ghemtio, Daniela Pellegrino, Pia J. Jokela (née Heinonen), Henri Xhaard and Marco G. Casteleijn

Pharmaceutics, 2022, 14, 1639
DOI: 10.3390/pharmaceutics14081639

Optical diagnosis of oral cavity lesions by label-free Raman spectroscopy

Levi Matthies, Medhanie T. Gebrekidan, Jasper F. Tegtmeyer, Nicolai Oetter, Maximilian Rohde, Tobias Vollkommer, Ralf Smeets, Waldemar Wilczak, Florian Stelzle, Martin Gosau, Andreas S. Braeuer and Christian Knipfer

Biomed. Opt. Express, 2021, 12, 836
DOI: 10.1364/BOE.409456

Cytotoxic Effects of 5-Azacytidine on Primary Tumour Cells and Cancer Stem Cells from Oral Squamous Cell Carcinoma: An In Vitro FTIRM Analysis

Valentina Notarstefano, Alessia Belloni, Simona Sabbatini, Chiara Pro, Giulia Orilisi, Riccardo Monterubbianesi, Vincenzo Tosco, Hugh J. Byrne, Lisa Vaccari and Elisabetta Giorgini

Cells, 2021, 10, 2127
DOI: 10.3390/cells10082127

Quantitative Raman Analysis of Carotenoid Protein Complexes in Aqueous Solution

Joy Udensi, Ekaterina Loskutova, James Loughman and Hugh J. Byrne

Molecules, 2022, 27, 4724
DOI: 10.3390/molecules27154724

Raman Microspectroscopic Investigation and Classification of Breast Cancer Pathological Characteristics

Heping Li, Tian Ning, Fan Yu, Yishen Chen, Baoping Zhang and Shuang Wang

Molecules, 2021, 26, 921
DOI: 10.3390/molecules26040921

Alkyne-tag Raman imaging and sensing of bioactive compounds

Kosuke Dodo, William J. Tipping, Hiroyuki Yamakoshi, Syusuke Egoshi, Toshiki Kubo, Yasuaki Kumamoto, Karen Faulds, Duncan Graham, Katsumasa Fujita and Mikiko Sodeoka

Nat Rev Methods Primers, 2025, 5
DOI: 10.1038/s43586-025-00389-9

Line Scan Raman Microspectroscopy for Label-Free Diagnosis of Human Pituitary Biopsies

Daniela Bovenkamp, Alexander Micko, Jeremias Püls, Fabian Placzek, Romana Höftberger, Greisa Vila, Rainer Leitgeb, Wolfgang Drexler, Marco Andreana, Stefan Wolfsberger and Angelika Unterhuber

Molecules, 2019, 24, 3577
DOI: 10.3390/molecules24193577

Action of euptox A from Ageratina adenophora juice on human cell lines: A top-down study using FTIR spectroscopy and protein profiling

Rebeca André, Joana Catarro, Dalia Freitas, Rita Pacheco, M. Conceição Oliveira, Maria Luísa Serralheiro and Pedro L. Falé

Toxicology in Vitro, 2019, 57, 217
DOI: 10.1016/j.tiv.2019.03.012

Raman spectroscopy combined with multivariate analysis to study the biochemical mechanism of lung cancer microwave ablation

Dongliang Song, Fan Yu, Shilin Chen, Yishen Chen, Qingli He, Zhe Zhang, Jingyuan Zhang and Shuang Wang

Biomed. Opt. Express, 2020, 11, 1061
DOI: 10.1364/BOE.383869

Raman difference spectroscopy and U-Net convolutional neural network for molecular analysis of cutaneous neurofibroma

Levi Matthies, Hendrik Amir-Kabirian, Medhanie T. Gebrekidan, Andreas S. Braeuer, Ulrike S. Speth, Ralf Smeets, Christian Hagel, Martin Gosau, Christian Knipfer, Reinhard E. Friedrich and Shaiju S. Nazeer

PLoS ONE, 2024, 19, e0302017
DOI: 10.1371/journal.pone.0302017

A new approach to assess post-mortem interval: A machine learning-assisted label-free ATR-FTIR analysis of human vitreous humor

Valentina Notarstefano, Chiara Santoni, Eva Montanari, Francesco Paolo Busardò, Angelo Montana, Giulia Orilisi, Paolo Mariani and Elisabetta Giorgini

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 327, 125326
DOI: 10.1016/j.saa.2024.125326

Understanding Secondary Structures of Silk Materials via Micro- and Nano-Infrared Spectroscopies

Jiajia Zhong, Yawen Liu, Jing Ren, Yuzhao Tang, Zeming Qi, Xiaojie Zhou, Xin Chen, Zhengzhong Shao, Min Chen, David L. Kaplan and Shengjie Ling

ACS Biomater. Sci. Eng., 2019, 5, 3161
DOI: 10.1021/acsbiomaterials.9b00305

Raman spectral signatures of cervical exfoliated cells from liquid-based cytology samples

Padraig Kearney, Damien Traynor, Franck Bonnier, Fiona M. Lyng, John J. O’Leary and Cara M. Martin

J. Biomed. Opt, 2017, 22, 1
DOI: 10.1117/1.JBO.22.10.105008

Increasing storage stability of freeze-dried plasma using trehalose

Raffaele Brogna, Harriëtte Oldenhof, Harald Sieme, Constança Figueiredo, Tobias Kerrinnes, Willem F. Wolkers and Xiaoming He

PLoS ONE, 2020, 15, e0234502
DOI: 10.1371/journal.pone.0234502

Surface-enhanced Raman spectroscopy (SERS) investigations of saliva for oral cancer diagnosis

A. Fălămaș, H. Rotaru and M. Hedeșiu

Lasers Med Sci, 2020, 35, 1393
DOI: 10.1007/s10103-020-02988-2

Synchrotron Radiation-Based FTIR Microspectroscopic Imaging of Traumatically Injured Mouse Brain Tissue Slices

Yuansen Guo, Tunan Chen, Shi Wang, Xiaojie Zhou, Hua Zhang, Dandan Li, Ning Mu, Mingjie Tang, Meidie Hu, Dongyun Tang, Zhongbo Yang, Jiajia Zhong, Yuzhao Tang, Hua Feng, Xuehua Zhang and Huabin Wang

ACS Omega, 2020, 5, 29698
DOI: 10.1021/acsomega.0c03285

How to draw the line – Raman spectroscopy as a tool for the assessment of biomedicines

Christel Kamp, Björn Becker, Walter Matheis, Volker Öppling and Isabelle Bekeredjian-Ding

Biological Chemistry, 2021, 402, 1001
DOI: 10.1515/hsz-2020-0388

Review of multidimensional data processing approaches for Raman and infrared spectroscopy

Rekha Gautam, Sandeep Vanga, Freek Ariese and Siva Umapathy

EPJ Techn Instrum, 2015, 2
DOI: 10.1140/epjti/s40485-015-0018-6

Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer

Daniela Bovenkamp, Ryan Sentosa, Elisabet Rank, Mikael T. Erkkilä, Fabian Placzek, Jeremias Püls, Wolfgang Drexler, Rainer A. Leitgeb, Nathalie Garstka, Shahrokh F. Shariat, Clara Stiebing, Iwan W. Schie, Jürgen Popp, Marco Andreana and Angelika Unterhuber

Applied Sciences, 2018, 8, 2371
DOI: 10.3390/app8122371

Confocal Raman microspectroscopic analysis on the time-dependent impact of DAPT, a γ-secretase inhibitor, to osteosarcoma cells

Jie Li, Jing Li, Jie Qin, Haishan Zeng, Kaige Wang, Difan Wang and Shuang Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 239, 118372
DOI: 10.1016/j.saa.2020.118372

Cellular Internalization of Beta-Carotene Loaded Polyelectrolyte Multilayer Capsules by Raman Mapping

Loredana F. Leopold, Oana Marișca, Ioana Oprea, Dumitrița Rugină, Maria Suciu, Mădălina Nistor, Maria Tofană, Nicolae Leopold and Cristina Coman

Molecules, 2020, 25, 1477
DOI: 10.3390/molecules25071477

Evaluation of nutrition components in Lanzhou lily bulb by confocal Raman microscopy

Yuee Li, Huihui Wang, Wenbo Zhang, Haining Wu and Zhong Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 244, 118837
DOI: 10.1016/j.saa.2020.118837

Liver changes induced by cadmium poisoning distinguished by confocal Raman imaging

Yuee Li, Rong Shen, Haining Wu, Linghui Yu, Zhong Wang and Degui Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 225, 117483
DOI: 10.1016/j.saa.2019.117483

Molecular Pathways and Pigments Underlying the Colors of the Pearl Oyster Pinctada margaritifera var. cumingii (Linnaeus 1758)

Pierre-Louis Stenger, Chin-Long Ky, Céline Reisser, Julien Duboisset, Hamadou Dicko, Patrick Durand, Laure Quintric, Serge Planes and Jeremie Vidal-Dupiol

Genes, 2021, 12, 421
DOI: 10.3390/genes12030421

Colony-to-cell Raman spectral features enhance interpretable single-cell detection of Bacillus

Qifeng Li, Hua Xia, Yi Sun, Lei Li, Yingxiao Peng, Feng Gao, Jiazheng Sun and Xiangyun Ma

Sensors and Actuators B: Chemical, 2026, 461, 139944
DOI: 10.1016/j.snb.2026.139944

Seeding multivariate algorithms for spectral analysis, a data augmentation approach to enhance analytical performance

M.E. Keating and H.J. Byrne

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126369
DOI: 10.1016/j.saa.2025.126369

Precise diagnosis of breast phyllodes tumors using Raman spectroscopy: Biochemical fingerprint, tumor metabolism and possible mechanism

Yifan Wu, Yaohui Wang, Chang He, Yan Wang, Jiayi Ma, Yanping Lin, Liheng Zhou, Shuguang Xu, Yumei Ye, Wenjin Yin, Jian Ye and Jingsong Lu

Analytica Chimica Acta, 2023, 1283, 341897
DOI: 10.1016/j.aca.2023.341897

Applicability of Raman spectroscopy on porcine parvovirus and porcine circovirus type 2 detection

Izabel C.V.P. Gogone, Glaucia H. Ferreira, Danielle Gava, Rejane Schaefer, Fabíola F. de Paula-Lopes, Raquel de A. Rocha and Flavia R.O. de Barros

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 249, 119336
DOI: 10.1016/j.saa.2020.119336

In vivo confocal Raman spectroscopy for intrinsic aging and photoaging assessment

Livia de Vasconcelos Nasser Caetano, Thiago de Oliveira Mendes, Edileia Bagatin, Helio Amante Miot, Juliana Laudiceia Marques Soares, Milvia Maria Simoes e Silva Enokihara and Airton Abrahao Martin

Journal of Dermatological Science, 2017, 88, 199
DOI: 10.1016/j.jdermsci.2017.07.011

Molecular monitoring of epithelial-to-mesenchymal transition in breast cancer cells by means of Raman spectroscopy

M. Marro, C. Nieva, R. Sanz-Pamplona and A. Sierra

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014, 1843, 1785
DOI: 10.1016/j.bbamcr.2014.04.012

Noise-free simulation of an FT-IR imaging hyperspectral dataset of pancreatic biopsy core bound by experiment

Tomasz P. Wrobel, Paulina Koziol, Magda K. Raczkowska, Danuta Liberda, Czeslawa Paluszkiewicz and Wojciech M. Kwiatek

Sci Data, 2019, 6
DOI: 10.1038/s41597-019-0260-x

Spectroscopic assessment of oxidative damage in biomolecules and tissues

Sükrü Caliskan, Harriëtte Oldenhof, Raffaele Brogna, Bita Rashidfarokhi, Harald Sieme and Willem F. Wolkers

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246, 119003
DOI: 10.1016/j.saa.2020.119003

Heterospectral Principal Component Analysis Two-Dimensional Correlation Spectrosocpy as a Robust Method for Determining Surface Adsorption Preference

Mahsa Torkamanasadi and Dennis K. Hore

Appl Spectrosc, 2026
DOI: 10.1177/00037028261433545

Sub-THz acoustic excitation of protein motion

Petra Papež, Franci Merzel and Matej Praprotnik

The Journal of Chemical Physics, 2023, 159
DOI: 10.1063/5.0163801

Rapid biochemical profiling of endothelial dysfunction in diabetes, hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra

Marta Z. Pacia, Lukasz Mateuszuk, Elzbieta Buczek, Stefan Chlopicki, Agnieszka Blazejczyk, Joanna Wietrzyk, Malgorzata Baranska and Agnieszka Kaczor

J Raman Spectroscopy, 2016, 47, 1310
DOI: 10.1002/jrs.4965

Evaluating data-mining strategies for label-free Raman microspectroscopic analysis of cellular processes in vitro: dynamic dimensionality reduction

Zohreh Mirveis, Nitin Patil and Hugh J. Byrne

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 359, 127923
DOI: 10.1016/j.saa.2026.127923

Monitoring the On-Surface Boronic Acid Condensation Process at the Nanoscale Using Tip-Enhanced Raman Spectroscopy

Yuanzhi Xia, Kim Greis, Chengcheng Xu, Naresh Kumar and Renato Zenobi

ACS Nano, 2025, 19, 6511
DOI: 10.1021/acsnano.4c17728

Raman spectroscopy analysis of human amniotic fluid cells from fetuses with myelomeningocele

Luca Pontiggia, Katarzyna Michalak-Micka, Nadine Hürlimann, Hesham K. Yosef, Roland Böni, Agnes S. Klar, Martin Ehrbar, Nicole Ochsenbein-Kölble, Thomas Biedermann and Ueli Moehrlen

Experimental Cell Research, 2024, 439, 114048
DOI: 10.1016/j.yexcr.2024.114048

Structural Changes of Amyloid Beta in Hippocampus of Rats Exposed to Ozone: A Raman Spectroscopy Study

Selva Rivas-Arancibia, Erika Rodríguez-Martínez, Isidro Badillo-Ramírez, Ulises López-González and José M. Saniger

Front. Mol. Neurosci., 2017, 10
DOI: 10.3389/fnmol.2017.00137

Egg characteristics assessment as an enabler for in-ovo sexing technology: A review

Shaomin Xu, Sifang Long, Zixian Su, Khawar Hayat, Lijuan Xie and Jinming Pan

Biosystems Engineering, 2025, 249, 41
DOI: 10.1016/j.biosystemseng.2024.11.008

Temperature-scanning infrared spectroscopic analysis of sugar glasses using principal component analysis

Dejia Liu, Harriëtte Oldenhof, Harald Sieme and Willem F. Wolkers

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 349, 127346
DOI: 10.1016/j.saa.2025.127346

In ovo sexing of chicken eggs by fluorescence spectroscopy

Roberta Galli, Grit Preusse, Ortrud Uckermann, Thomas Bartels, Maria-Elisabeth Krautwald-Junghanns, Edmund Koch and Gerald Steiner

Anal Bioanal Chem, 2017, 409, 1185
DOI: 10.1007/s00216-016-0116-6

Raman spectroscopy accurately classifies burn severity in an ex vivo model

Hanglin Ye, Rahul, Uwe Kruger, Tianmeng Wang, Sufei Shi, Jack Norfleet and Suvranu De

Burns, 2021, 47, 812
DOI: 10.1016/j.burns.2020.08.006

Application of Chemometrics Approaches to Analysis of Mid-Infrared Spectra of Ibuprofen Diluted in Supercritical Carbon Dioxide

Roman D. Oparin and Michael G. Kiselev

Appl Spectrosc, 2018, 72, 1548
DOI: 10.1177/0003702818775731

X-ray irradiation effects on nuclear and membrane regions of single SH-SY5Y human neuroblastoma cells investigated by Raman micro-spectroscopy

I. Delfino, G. Perna, V. Ricciardi, M. Lasalvia, L. Manti, V. Capozzi and M. Lepore

Journal of Pharmaceutical and Biomedical Analysis, 2019, 164, 557
DOI: 10.1016/j.jpba.2018.11.028

Predicting Metastasis from Cues of Metastatic Cancer Stem-like Cells-3D-Ultrasensitive Metasensor at a Single-Cell Level

Priya Dharmalingam, Krishnan Venkatakrishnan and Bo Tan

ACS Nano, 2021, 15, 9967
DOI: 10.1021/acsnano.1c01436

Species identification and strain discrimination of fermentation yeasts Saccharomyces cerevisiae and Saccharomyces uvarum using Raman spectroscopy and convolutional neural networks

Kaidi Wang, Jing Chen, Jay Martiniuk, Xiangyun Ma, Qifeng Li, Vivien Measday, Xiaonan Lu and Edward G. Dudley

Appl Environ Microbiol, 2023, 89
DOI: 10.1128/aem.01673-23

Raman spectral analysis for rapid screening of dengue infection

T. Mahmood, H. Nawaz, A. Ditta, M.I. Majeed, M.A. Hanif, N. Rashid, H.N. Bhatti, H.F. Nargis, M. Saleem, F. Bonnier and H.J. Byrne

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 200, 136
DOI: 10.1016/j.saa.2018.04.018

Formation of Prenylated Chalcone Xanthohumol Cocrystals: Single Crystal X-ray Diffraction, Vibrational Spectroscopic Study Coupled with Multivariate Analysis

Iwona Budziak, Marta Arczewska and Daniel M. Kamiński

Molecules, 2019, 24, 4245
DOI: 10.3390/molecules24234245

Raman-guided analysis of drug response combined with chemometrics helps monitor the effect of ruxolitinib on acute lymphoblastic leukemia

Adriana Adamczyk, Justyna Jakubowska, Marta Szewczyk, Anna M. Nowakowska, Kacper Stawoski, Agata Pastorczak, Wojciech Młynarski, Małgorzata Baranska, Kinga Ostrowska and Katarzyna Majzner

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 354, 127566
DOI: 10.1016/j.saa.2026.127566

Characterization and prediction of viral loads of Hepatitis B serum samples by using surface-enhanced Raman spectroscopy (SERS)

Shamsheer Ahmad, Muhammad Irfan Majeed, Haq Nawaz, Muhammad Rizwan Javed, Nosheen Rashid, Muhammad Abubakar, Fatima Batool, Saba Bashir, Muhammad Kashif, Saqib Ali, Mamoona Tahira, Shaheera Tabbasum and Imran Amin

Photodiagnosis and Photodynamic Therapy, 2021, 35, 102386
DOI: 10.1016/j.pdpdt.2021.102386

Differentiating responses of lung cancer cell lines to Doxorubicin exposure: in vitro Raman micro spectroscopy, oxidative stress and bcl‐2 protein expression

Zeineb Farhane, Franck Bonnier, Marcus Alexander Maher, Jane Bryant, Alan Casey and Hugh James Byrne

Journal of Biophotonics, 2017, 10, 151
DOI: 10.1002/jbio.201600019

Rapid and Sensitive Screening of 17β-Estradiol Estrogenicity Using Fourier Transform Infrared Imaging Spectroscopy (FT-IRIS)

Candice M. Johnson, Nancy Pleshko, Mohan Achary and Rominder P. S. Suri

Environ. Sci. Technol., 2014, 48, 4581
DOI: 10.1021/es5000676

Spectroscopic signature of ZnO NP-induced cell death modalities assessed by non-negative PCA

Mirjana Miletić, Aleksandra Vilotić, Lela Korićanac, Jelena Žakula, Milica Jovanović Krivokuća, Zorana Dohčević-Mitrović and Sonja Aškrabić

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 288, 122180
DOI: 10.1016/j.saa.2022.122180

Raman spectroscopic profiling of cell death induced by cytotoxic copper(II), manganese(II), and silver(I) complexes containing dicarboxylate and 1,10-phenanthroline ligands: novel insights into in vitro mechanisms

Ella O’Sullivan, Denis O’Shea, Michael Devereux, Orla Howe and Hugh J Byrne

Metallomics, 2026, 18
DOI: 10.1093/mtomcs/mfaf044

Inactivation effects, kinetics and mechanisms of air- and nitrogen-based cold atmospheric plasma on Pseudomonas aeruginosa

Yijie Zhao, Lele Shao, Lihong Jia, Bo Zou, Ruitong Dai, Xingmin Li and Fei Jia

Innovative Food Science & Emerging Technologies, 2022, 79, 103051
DOI: 10.1016/j.ifset.2022.103051

Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm

Monica Marro, Claudia Nieva, Anna de Juan and Angels Sierra

Anal. Chem., 2018, 90, 5594
DOI: 10.1021/acs.analchem.7b04527

Vibrational spectroscopy for discrimination and quantification of clinical chemotherapeutic preparations

Alaa A. Makki, Victor Massot, Hugh J. Byrne, Renaud Respaud, Dominique Bertrand, Elhadi Mohammed, Igor Chourpa and Franck Bonnier

Vibrational Spectroscopy, 2021, 113, 103200
DOI: 10.1016/j.vibspec.2020.103200

Label-free assaying of testosterone and growth hormones in blood using surface-enhanced Raman spectroscopy

Annah M. Ondieki, Zephania Birech, Kenneth A. Kaduki, Peter W. Mwangi, Moses Juma and Boniface M. Chege

Vibrational Spectroscopy, 2023, 129, 103605
DOI: 10.1016/j.vibspec.2023.103605

Estimation of the content of lipids composing endothelial lipid droplets based on Raman imaging

Marta Z. Pacia, Katarzyna Majzner, Krzysztof Czamara, Magdalena Sternak, Stefan Chlopicki and Malgorzata Baranska

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020, 1865, 158758
DOI: 10.1016/j.bbalip.2020.158758