Synthesis of oligodeoxynucleotides using the oxidatively cleavable 4-methoxytritylthio (MMTrS) group for protection of the 5′-hydroxyl group

Kohji Seio, Miyuki Shiraishi, Eri Utagawa, Akihiro Ohkubo and Mitsuo Sekine

New J. Chem., 2010, 34, 984
DOI: 10.1039/b9nj00678h

RNA–peptide conjugate synthesis by inverse-electron demand Diels–Alder reaction

Sandeep Ameta, Juliane Becker and Andres Jäschke

Org. Biomol. Chem., 2014, 12, 4701
DOI: 10.1039/C4OB00076E

Two short approaches to the COVID-19 drug β-d-N4-hydroxycytidine and its prodrug molnupiravir

Kevin E. Persaud, Rajesh R. Sahu, Michelle C. Neary, Anant R. Kapdi and Mahesh K. Lakshman

Org. Biomol. Chem., 2024, 22, 735
DOI: 10.1039/D3OB02039H

Efficient synthesis of 5-hydroxymethyl-, 5-formyl-, and 5-carboxyl-2′-deoxycytidine and their triphosphates

Qi Sun, Jian Sun, Shan-Shan Gong, Cheng-Jun Wang, Shou-Zhi Pu and Fu-De Feng

RSC Adv., 2014, 4, 36036
DOI: 10.1039/C4RA07670B

The Sulfo‐Click Reaction and Dual Labeling of Nucleosides

Guillaume Clavé, Jean‐Jacques Vasseur and Michael Smietana

CP Nucleic Acid Chemistry, 2020, 83
DOI: 10.1002/cpnc.120

General Approach to N6,C5′-Difunctionalization of Adenosine

Dellamol Sebastian, Sakilam Satishkumar, Padmanava Pradhan, Lijia Yang and Mahesh K. Lakshman

J. Org. Chem., 2022, 87, 18
DOI: 10.1021/acs.joc.1c01587

Solvent-modulated Pd/C-catalyzed deprotection of silyl ethers and chemoselective hydrogenation

Takashi Ikawa, Kazuyuki Hattori, Hironao Sajiki and Kosaku Hirota

Tetrahedron, 2004, 60, 6901
DOI: 10.1016/j.tet.2004.05.098

Ultrasonic-Assisted Deprotection of tert-Butyldimethylsilyl Ethers with Bromotrichloromethane in Methanol

Jian Sun, Shan Shan Gong and Qi Sun

AMR, 2013, 830, 230
DOI: 10.4028/www.scientific.net/AMR.830.230

ChemInform Abstract: Facile and Highly Selective 5′‐Desilylation of Multisilylated Nucleosides.

Xue‐Feng Zhu, Howard J. Williams and A. Ian Scott

ChemInform, 2000, 31
DOI: 10.1002/chin.200048227

AN IMPROVED SYNTHESIS OF THE DINUCLEOTIDES pdCpA AND pdCpdA

Xue-Feng Zhu and A. Ian Scott

Nucleosides, Nucleotides and Nucleic Acids, 2001, 20, 197
DOI: 10.1081/NCN-100002081

Selective monodeprotection of bis-silyl ethers

R. David Crouch

Tetrahedron, 2004, 60, 5833
DOI: 10.1016/j.tet.2004.04.042

Microwave-Assisted Direct Amination: Rapid Access to Multi-Functionalized N6-Substituted Adenosines

Trent D. Ashton and Peter J. Scammells

Aust. J. Chem., 2008, 61, 49
DOI: 10.1071/CH07340

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

Andrej Kolarovic, Emma Schweizer, Emily Greene, Mark Gironda, Pradeep S. Pallan, Martin Egli and Eriks Rozners

J. Am. Chem. Soc., 2009, 131, 14932
DOI: 10.1021/ja904926e

Synthesis and Properties of Isobicyclo‐DNA

Anna‐Barbara Gerber and Christian J. Leumann

Chemistry A European J, 2013, 19, 6990
DOI: 10.1002/chem.201300487

Synthesis of a bifunctional cytidine derivative and its conjugation to RNA for in vitro selection of a cytidine deaminase ribozyme

Nico Rublack and Sabine Müller

Beilstein J. Org. Chem., 2014, 10, 1906
DOI: 10.3762/bjoc.10.198

Unprecedented formation of 8(R),5′-O-cycloribonucleosides through a triflation reaction of purine ribonucleosides

Claire Amiable and Sylvie Pochet

Tetrahedron, 2015, 71, 2525
DOI: 10.1016/j.tet.2015.03.020

Synthesis of 2′-O-[3-(N-methylsulfamoyl)propan-1-yl]ribothymidine as a potentially applicable 2′-modified nucleoside for antisense oligonucleotides

Takahito Tomori, Koya Uekusa, Aya Koyama, Takayuki Kanagawa, Yoshiaki Masaki and Kohji Seio

Bioorganic & Medicinal Chemistry, 2022, 73, 117002
DOI: 10.1016/j.bmc.2022.117002

Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis

Julian A Ferreras, Jae-Sang Ryu, Federico Di Lello, Derek S Tan and Luis E N Quadri

Nat Chem Biol, 2005, 1, 29
DOI: 10.1038/nchembio706

Chemo-enzymatic synthesis of adenine substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs

Peiling Su, James D. Bretz, Gihan S. Gunaratne, Jonathan S. Marchant, Timothy F. Walseth and James T. Slama

Bioorganic & Medicinal Chemistry, 2021, 30, 115901
DOI: 10.1016/j.bmc.2020.115901

Intramolecular Participation of Amino Groups in the Cleavage and Isomerization of Ribonucleoside 3′‐Phosphodiesters: The Role in Stabilization of the Phosphorane Intermediate

Luigi Lain, Harri Lönnberg and Tuomas Lönnberg

Chemistry A European J, 2013, 19, 12424
DOI: 10.1002/chem.201301711

Aqueous Trichloroacetic Acid: Another Useful Reagent for Highly Selective 5′-Desilylation of Multisilylated Nucleosides

Xue-Feng Zhu, Howard J. Williams and A. Ian Scott

Synthetic Communications, 2003, 33, 2011
DOI: 10.1081/SCC-120021027

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

Anna Heib, Giuliana Niro, Stefanie C. Weck, Stefan Koppermann and Christian Ducho

Molecules, 2019, 25, 22
DOI: 10.3390/molecules25010022

Novel Synthetic Approach to Multibenzoylated Nucleosides

Xue‐Feng Zhu and A. Ian Scott

Synthetic Communications, 2008, 38, 1346
DOI: 10.1080/00397910801916280

Synthesis of photocaged 6- O -(2-nitrobenzyl)guanosine and 4- O -(2-nitrobenzyl) uridine triphosphates for photocontrol of the RNA transcription reaction

Kentaro Ohno, Daiki Sugiyama, Leo Takeshita, Takashi Kanamori, Yoshiaki Masaki, Mitsuo Sekine and Kohji Seio

Bioorganic & Medicinal Chemistry, 2017, 25, 6007
DOI: 10.1016/j.bmc.2017.09.032

Single Diastereomers of the Clinical Anticancer ProTide Agents NUC-1031 and NUC-3373 Preferentially Target Cancer Stem CellsIn Vitro

Magdalena Slusarczyk, Michaela Serpi, Essam Ghazaly, Benson M. Kariuki, Christopher McGuigan and Chris Pepper

J. Med. Chem., 2021, 64, 8179
DOI: 10.1021/acs.jmedchem.0c02194

Aminoacyl-tRNA Synthetase Inhibitors as Potent and Synergistic Immunosuppressants

Pieter Van de Vijver, Tomasz Ostrowski, Brian Sproat, Jozef Goebels, Omer Rutgeerts, Arthur Van Aerschot, Mark Waer and Piet Herdewijn

J. Med. Chem., 2008, 51, 3020
DOI: 10.1021/jm8000746

Synthesis and Modification of Cordycepin-Phosphoramidate ProTide Derivatives for Antiviral Activity and Metabolic Stability

Aticha Thiraporn, Thanat Tiyasakulchai, Thitiphong Khamkhenshorngphanuch, Marie Hoarau, Ratthiya Thiabma, Suppachoke Onnome, Amporn Suphatrakul, Jaraspim Narkpuk, Chanya Srisaowakarn, Suwimon Manopwisedjaroen, Kitlada Srichomthong, Suradej Hongeng, Arunee Thitithanyanont, Peera Jaru-ampornpan, Sewan Theeramunkong, Bunpote Siridechadilok and Nitipol Srimongkolpithak

ACS Bio Med Chem Au, 2025, 5, 89
DOI: 10.1021/acsbiomedchemau.4c00071

Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents

Daniel Wiegmann, Stefan Koppermann, Marius Wirth, Giuliana Niro, Kristin Leyerer and Christian Ducho

Beilstein J. Org. Chem., 2016, 12, 769
DOI: 10.3762/bjoc.12.77

Reversible site-specific tagging of enzymatically synthesized RNAs using aldehyde–hydrazine chemistry and protease-cleavable linkers

Stephanie Pfander, Roberto Fiammengo, Srećko I. Kirin, Nils Metzler-Nolte and Andres Jäschke

Nucleic Acids Research, 2007, 35, e25
DOI: 10.1093/nar/gkl1110

5'‐O‐(2‐Isopropoxyprop‐2‐yl)‐protected Phosphoramidite Building Blocks in the Liquid Phase Oligonucleotide Synthesis

Zehong Liang, Petja Rosenqvist, Ella Pajuniemi, Mikko Ora, Petri Heinonen, Pasi Virta and Mikko Oivanen

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202300614

Recent advances in the synthesis of 4′-truncated nucleoside phosphonic acid analogues

Guang Huan Shen and Joon Hee Hong

Carbohydrate Research, 2022, 513, 108517
DOI: 10.1016/j.carres.2022.108517

Second Generation Catalytic Enantioselective Nucleophilic Desymmetrization at Phosphorus (V): Improved Generality, Efficiency and Modularity

Michele Formica, Branislav Ferko, Thomas Marsh, Timothy A. Davidson, Ken Yamazaki and Darren J. Dixon

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202400673

Syntheses of nucleosides with a 1′,2′-β-lactam moiety as potential inhibitors of hepatitis C virus NS5B polymerase

Qun Dang, Zhibo Zhang, Yunfeng Bai, Ruijun Sun, Jie Yin, Tongqian Chen, Stephane Bogen, Vinay Girijavallabhan, David B. Olsen and Peter T. Meinke

Tetrahedron Letters, 2014, 55, 5576
DOI: 10.1016/j.tetlet.2014.08.072

Phosphoramidates and phosphonamidates (ProTides) with antiviral activity

Magdalena Slusarczyk, Michaela Serpi and Fabrizio Pertusati

Antivir Chem Chemother, 2018, 26
DOI: 10.1177/2040206618775243

Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N6,5′-bis-ureido- and 5′-carbamoyl-N6-ureidoadenosine derivatives

Jadd R. Shelton, Christopher E. Cutler, Marcelio Oliveira, Jan Balzarini and Matt A. Peterson

Bioorganic & Medicinal Chemistry, 2012, 20, 1008
DOI: 10.1016/j.bmc.2011.11.043

Development of a Kilogram-Scale Synthesis of a Key Ulevostinag Subunit Part I: Accessing a Keto-Nucleoside Intermediate from Guanosine

Ben W. H. Turnbull, Feng Peng, Andrew J. Neel, Tamas Benkovics, Zhuqing Liu, Cheol K. Chung, Zhiguo Jake Song, Lushi Tan, Khateeta M. Emerson, Chengqian Xiao, Yi Zhang and Benjamin D. Sherry

Org. Process Res. Dev., 2023, 27, 448
DOI: 10.1021/acs.oprd.2c00397

Well-Defined DNA Nanoparticles Templated by Self-Assembled M12L24 Molecular Spheres and Binding of Complementary Oligonucleotides

Takashi Kikuchi, Sota Sato and Makoto Fujita

J. Am. Chem. Soc., 2010, 132, 15930
DOI: 10.1021/ja108334g

5′-Phosphonate modified oligoadenylates as potent activators of human RNase L

Tomáš Lášek, Magdalena Petrová, Ivana Košiová, Ondřej Šimák, Miloš Buděšínský, Jaroslav Kozák, Jan Snášel, Zdeněk Vavřina, Gabriel Birkuš, Ivan Rosenberg and Ondřej Páv

Bioorganic & Medicinal Chemistry, 2022, 56, 116632
DOI: 10.1016/j.bmc.2022.116632

Design and Synthesis of α-Carboxy Phosphononucleosides

Sebastien Debarge, Jan Balzarini and Anita R. Maguire

J. Org. Chem., 2011, 76, 105
DOI: 10.1021/jo101738e

Base substituted 5′-O-(N-isoleucyl)sulfamoyl nucleoside analogues as potential antibacterial agents

Bharat Gadakh, Gaston Vondenhoff, Eveline Lescrinier, Jef Rozenski, Mathy Froeyen and Arthur Van Aerschot

Bioorganic & Medicinal Chemistry, 2014, 22, 2875
DOI: 10.1016/j.bmc.2014.03.040

An overview of stereoselective synthesis of α-aminophosphonic acids and derivatives

Mario Ordóñez, Haydée Rojas-Cabrera and Carlos Cativiela

Tetrahedron, 2009, 65, 17
DOI: 10.1016/j.tet.2008.09.083

Stereoselective Synthesis of Uridine-Derived Nucleosyl Amino Acids

Anatol P. Spork, Daniel Wiegmann, Markus Granitzka, Dietmar Stalke and Christian Ducho

J. Org. Chem., 2011, 76, 10083
DOI: 10.1021/jo201935w

Second Generation Catalytic Enantioselective Nucleophilic Desymmetrization at Phosphorus (V): Improved Generality, Efficiency and Modularity

Michele Formica, Branislav Ferko, Thomas Marsh, Timothy A. Davidson, Ken Yamazaki and Darren J. Dixon

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202400673

Radical Cyclization Approach to Cyclonucleosides

Maria Luisa Navacchia, Antonio Manetto, Pier Carlo Montevecchi and Chryssostomos Chatgilialoglu

Eur J Org Chem, 2005, 2005, 4640
DOI: 10.1002/ejoc.200500398

Aqueous trifluoroacetic acid—an efficient reagent for exclusively cleaving the 5′-end of 3′,5′-TIPDS protected ribonucleosides

Xue-Feng Zhu, Howard J Williams and A.Ian Scott

Tetrahedron Letters, 2000, 41, 9541
DOI: 10.1016/S0040-4039(00)01685-3

Uncoupling Molecular Testing for SARS-CoV-2 From International Supply Chains

Jo-Ann L. Stanton, Rory O'Brien, Richard J. Hall, Anastasia Chernyavtseva, Hye Jeong Ha, Lauren Jelley, Peter D. Mace, Alexander Klenov, Jackson M. Treece, John D. Fraser, Fiona Clow, Lewis Clarke, Yongdong Su, Harikrishnan M. Kurup, Vyacheslav V. Filichev, William Rolleston, Lee Law, Phillip M. Rendle, Lawrence D. Harris, James M. Wood, Thomas W. Scully, James E. Ussher, Jenny Grant, Timothy A. Hore, Tim V. Moser, Rhodri Harfoot, Blair Lawley, Miguel E. Quiñones-Mateu, Patrick Collins and Richard Blaikie

Front. Public Health, 2022, 9
DOI: 10.3389/fpubh.2021.808751

Facile Silylation of Cyclitols Using Silyl Bis(triflates)

Anke Topp, Martin Köckerling, Helmut Reinke, Ralf Miethchen and Constantin Mamat

Eur J Inorg Chem, 2018, 2018, 1302
DOI: 10.1002/ejic.201701327

Deprotection of t-butyldimethylsilyl ethers promoted by cerium(IV) triflate

Giuseppe Bartoli, Giovanna Cupone, Renato Dalpozzo, Antonio De Nino, Loredana Maiuolo, Antonio Procopio, Letizia Sambri and Antonio Tagarelli

Tetrahedron Letters, 2002, 43, 5945
DOI: 10.1016/S0040-4039(02)01254-6

Multistep Synthesis of Analogues of Remdesivir: Incorporating Heterocycles at the C-1′ Position

Savio Cardoza, Manoj Kumar Shrivash, Laura Riva, Arnab K. Chatterjee, Ajay Mandal and Vibha Tandon

J. Org. Chem., 2023, 88, 9105
DOI: 10.1021/acs.joc.3c00754

Discovery of Inhibitors of Leishmania β-1,2-Mannosyltransferases Using a Click-Chemistry-Derived Guanosine Monophosphate Library

Phillip van der Peet, Julie E. Ralton, Malcolm J. McConville, Spencer J. Williams and Anna Kristina Croft

PLoS ONE, 2012, 7, e32642
DOI: 10.1371/journal.pone.0032642