Issue 100, 2017

Sensing the impact of environment on small molecule differentiation of RNA sequences

Abstract

Using pattern recognition of RNA with small molecules (PRRSM) with fluorescent RNA chemosensors and aminoglycosides, we reveal the impact of changing environmental conditions on the differentiation of a range of RNA structures as well as the ability to predict different sequence/size compositions of five canonical RNA motifs.

Graphical abstract: Sensing the impact of environment on small molecule differentiation of RNA sequences

Supplementary files

Article information

Article type
Communication
Submitted
13 sep. 2017
Accepted
24 nóv. 2017
First published
28 nóv. 2017

Chem. Commun., 2017,53, 13363-13366

Sensing the impact of environment on small molecule differentiation of RNA sequences

C. S. Eubanks and A. E. Hargrove, Chem. Commun., 2017, 53, 13363 DOI: 10.1039/C7CC07157D

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