Issue 84, 2018

Arylation of benzyl amines with aromatic nitriles

Abstract

In the past years, the activations of aromatic nitriles for radical arylations under photoirradiation have been developed. We here report the first example of radical arylations using aromatic nitriles without the assistance of photoirradiation. Importantly, with this method, the direct arylation of C(sp3)–H in benzyl amines provided a practical method for the synthesis of diarylmethylamines without the use of precious transition metal catalysts.

Graphical abstract: Arylation of benzyl amines with aromatic nitriles

Supplementary files

Article information

Article type
Communication
Submitted
06 ágú. 2018
Accepted
24 sep. 2018
First published
25 sep. 2018

Chem. Commun., 2018,54, 11881-11884

Arylation of benzyl amines with aromatic nitriles

Y. Lei, J. Yang, R. Qi, S. Wang, R. Wang and Z. Xu, Chem. Commun., 2018, 54, 11881 DOI: 10.1039/C8CC06408C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements