Issue 21, 2018
From the journal:

Analytical Methods

Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine†

Ibrahim Kaya, ORCID logo ab   Eva Jennische,c   Stefan Langec  and  Per Malmberg ORCID logo *bd  

* Corresponding authors

a Department of Chemistry and Molecular Biology, University of Gothenburg, Sweden

b The Gothenburg Imaging Mass Spectrometry (Go:IMS) Platform, University of Gothenburg and Chalmers University of Technology, Gothenburg 412 96, Sweden
E-mail: malmper@chalmers.se

c Institute of Biomedicine, Gothenburg 413 90, Sweden

d Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden

Abstract

Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features.

Graphical abstract: Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8AY00645H
Article type
Communication
Submitted
23 mar. 2018
Accepted
02 maí 2018
First published
03 maí 2018
This article is Open Access
Creative Commons BY-NC license

Anal. Methods, 2018,10, 2428-2435

Permissions

Request permissions

Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

I. Kaya, E. Jennische, S. Lange and P. Malmberg, Anal. Methods, 2018, 10, 2428 DOI: 10.1039/C8AY00645H

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements