Issue 19, 2016

Target-triggered autonomous assembly of DNA polymer chains and its application in colorimetric nucleic acid detection

Abstract

A novel target-triggered DNA autonomous assembly pathway for the formation of one-dimensional DNA polymer chains was proposed based on the catalyzed hairpin assembly and sticky end self-assembly, which led to an enzyme-free and signal amplified gold nanoparticle (AuNP) based colorimetric nucleic acid assay with picomolar sensitivity and specificity.

Graphical abstract: Target-triggered autonomous assembly of DNA polymer chains and its application in colorimetric nucleic acid detection

Supplementary files

Article information

Article type
Communication
Submitted
06 jan. 2016
Accepted
26 mar. 2016
First published
28 mar. 2016

J. Mater. Chem. B, 2016,4, 3191-3194

Target-triggered autonomous assembly of DNA polymer chains and its application in colorimetric nucleic acid detection

J. Dai, H. He, Z. Duan, C. Zhou, Y. Long, B. Zheng, J. Du, Y. Guo and D. Xiao, J. Mater. Chem. B, 2016, 4, 3191 DOI: 10.1039/C6TB00029K

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