Issue 3, 2019

Single-cell assay on microfluidic devices

Abstract

Advances in microfluidic techniques have prompted researchers to study the inherent heterogeneity of single cells in cell populations. This would be helpful in the identification of major diseases and the design of personalized medicine. Different microfluidic approaches provide a variety of functions in the process of single-cell analysis. In this review, we take a broad overview of various microfluidic-based approaches for single-cell isolation, single-cell lysis, and single-cell analysis. Up-to-date flagship techniques and the pros and cons of these methods are discussed in detail.

Graphical abstract: Single-cell assay on microfluidic devices

Article information

Article type
Critical Review
Submitted
12 jún. 2018
Accepted
22 ágú. 2018
First published
22 ágú. 2018

Analyst, 2019,144, 808-823

Single-cell assay on microfluidic devices

Q. Huang, S. Mao, M. Khan and J. Lin, Analyst, 2019, 144, 808 DOI: 10.1039/C8AN01079J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements