Issue 24, 2018

Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

Abstract

Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.

Graphical abstract: Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

Supplementary files

Article information

Article type
Communication
Submitted
23 jan. 2018
Accepted
23 feb. 2018
First published
26 feb. 2018

Chem. Commun., 2018,54, 2990-2993

Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

E. L. Borges, M. T. Ignasiak, Y. Velichenko, G. Perin, C. A. Hutton, M. J. Davies and C. H. Schiesser, Chem. Commun., 2018, 54, 2990 DOI: 10.1039/C8CC00565F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements