An efficient method for total syntheses of avenaciolide and isoavenaciolide via tungsten-π-allyl complexes

Abstract

Total syntheses of avenaciolide and isoavenaciolide were achieved in six and three steps respectively based on starting chloropropargyl derivatives; the key step in such syntheses involves intramolecular alkoxycarbonylation of tungsten-η¹-propargyl complexes.

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