Structure–property relationships in chalcones with extended π-conjugation: ICT perturbation and red fluorescence

Brian Corbin, Paityn Houglan, Wei-Yuan Chen, Christopher J. Ziegler and Yi Pang

Mater. Adv., 2026
DOI: 10.1039/D5MA01288K

Tyrosinase inhibitory activity of propolis from Jeju Island, Korea

Chie Watanabe, Daisuke Fujinami, Chihiro Honda, Mok-Ryeon Ahn and Shigenori Kumazawa

Bioscience, Biotechnology, and Biochemistry, 2025, 89, 787
DOI: 10.1093/bbb/zbaf024

Pharmacological potential of natural chalcones: a recent studies and future perspective

Suman Adhikari, Priyatosh Nath, Vishal Kumar Deb, Niranjan Das, Antara Banerjee, Surajit Pathak and Asim K. Duttaroy

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1570385

Appraisal of antioxidant scavenging and antibiofilm capacities of pyrazolic, isoxazolic-based chalcones and aurones: Synthesis, molecular docking, simulation, and ADME properties

Misbah Irshad, Mahmood Ahmed, Ali Abbas Aslam, Mohammed H.AL Mughram, Mehwish Khushi, Affifa Tajammal, Masooma Irfan and Muhammad Muddassar

Letters in Drug Design & Discovery, 2025, 22, 100256
DOI: 10.1016/j.lddd.2025.100256

Interaction of flavonoids with DNA: implications in cancer treatment

Dhanashri A. Raskar, Diksha Uday and Ekta Khattar

Mol Biol Rep, 2026, 53
DOI: 10.1007/s11033-026-11809-8

Computationally guided synthesis and biological profiling of chalcones as antioxidant and anti-inflammatory activities

Hafiz Aamir Ali Kharl, Muhammad Naeem, Shakira Ghazanfar, Arifa Mehreen, Hasnain Haider, Sumel Ashique, Sabina Yasmin, Fatimah M. Al-Salem and Md Yousuf Ansari

Inflammopharmacol, 2026, 34, 1929
DOI: 10.1007/s10787-026-02134-4

Relevance of Anthocyanin Metabolites Generated During Digestion on Bioactivity Attributed to Intact Anthocyanins

Claudia I. Victoria-Campos, José de Jesús Ornelas-Paz, Claudio Rios-Velasco, Saul Ruiz-Cruz, Juan Ornelas-Paz, Carmen L. Del Toro-Sánchez, Enrique Márquez-Ríos and Rogelio Calderón-Loera

Foods, 2024, 13, 4066
DOI: 10.3390/foods13244066

Extraction of chalcones from the dry vegetable raw materials by extraction

A. S. Pashina, K. F. Yankiv, S. A. Romanenko and S. D. Pozhidaeva

jour, 2026, 16, 141
DOI: 10.21869/2223-1528-2026-16-1-141-157

Synthesis of Heterocyclic Chalcone Analogues Containing Chromene and 1-Hydroxyimidazole Moieties

Elizaveta I. Basanova, Ekaterina M. Kulinich, Ivan A. Moskalev, Alexey Yu. Fedorov, Sergey G. Arkhipov, Ol’ga I. Yarovaya and Polina A. Nikitina

Russ J Gen Chem, 2025, 95, 3635
DOI: 10.1134/S107036322560657X

Medicinal chemistry perspective of chalcone derivatives as anticancer agents: synthetic strategy, biological activity, and structure-activity relationship

Aryadipto Dasgupta, R. Rajesh, Pronoy Kanti Das, Gurubasavaraja Swamy Puravarga Matada, Prasad Sanjay Dhiwar and Arghya Paik

Mol Divers, 2026
DOI: 10.1007/s11030-025-11434-w

Mechanistic insights into natural product-driven modulation of NLRP3-inflammasome signalling in metabolic syndrome

Prastuti Sahariah, Lunasmrita Saikia, Albert Bharali, Douglas Law, Saikat Sen, Lalita Ambigai Sivasamugham and Partha Pratim Dutta

Inflamm. Res., 2026, 75
DOI: 10.1007/s00011-026-02253-2

Understanding the binding mechanisms of hydroxy-chalcone-based 24-membered macrocyclic bis-epoxide with beta-lactoglobulin

Rina Mondal, Mohd Afzal and Nayim Sepay

International Journal of Biological Macromolecules, 2025, 286, 138130
DOI: 10.1016/j.ijbiomac.2024.138130

Microwave-Assisted Synthesis of Azo-Chalcone Using Porous MOF Catalysts: Insights from DFT and Molecular Docking

Sameera Sh. Mohammed Ameen, Myasar Kh. Ibrahim, Shireen R. Mohammed, Mohamed Chellegui, Haydar Mohammad-Salim, Khalid M. Omer and Jesus Vicente de Julián-Ortiz

Catal Lett, 2025, 155
DOI: 10.1007/s10562-025-05119-0

Determination of the Inhibitory Potential of Chalcones on Myeloperoxidase Enzyme Activity: In vitro and Molecular Docking Studies

Nurgül Abul, Yeliz Demir, Aykut Öztekin and Hasan Özdemir

Cell Biochem Biophys, 2025, 83, 3383
DOI: 10.1007/s12013-025-01719-0

Advancing profiling of secondary antioxidant metabolites in Allium cepa PDO leaf extract: Online comprehensive two-dimensional liquid chromatography with high-resolution mass spectrometry and pre-column DPPH assay

Giovanna Aquino, Eduardo Maria Sommella, Emanuela Salviati, Michele Manfra, Giulia Auriemma, Pietro Campiglia, Giacomo Pepe and Manuela Giovanna Basilicata

Journal of Chromatography A, 2025, 1749, 465877
DOI: 10.1016/j.chroma.2025.465877

Sequential extraction of chalcones from Libidibia ferrea Mart. fruits by green pressurised fluids

J.R.S. Botelho, R.N. Carvalho, H.C. de Sousa and M.E.M. Braga

The Journal of Supercritical Fluids, 2026, 228, 106767
DOI: 10.1016/j.supflu.2025.106767

Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review

Junwei Chen, Zhonglang Gou, Yufei Huang, Qianhui Yu, An Na Kim, Wenchao Shi and You Zhou

Pharmaceuticals, 2025, 18, 695
DOI: 10.3390/ph18050695

Pharmacological exploration of natural 6-hydroxy flavone: A promising moiety

Hitesh Patil, Siddheshwar Parmeshwar Khule, Manish Gagrani and Sachin Dattram Pawar

Fitoterapia, 2025, 184, 106647
DOI: 10.1016/j.fitote.2025.106647

Chalcone A Natural Corrosion Inhibitor and Its Role in Promoting Sustainable Development

Rajaa Salah Raisan and Mahdi Salih Shihab

IOP Conf. Ser.: Earth Environ. Sci., 2025, 1507, 012030
DOI: 10.1088/1755-1315/1507/1/012030

Immunomodulatory Effects of Natural Products in Breast Cancer: From Molecular Mechanisms to Clinical Translation

Pooja Dave, Anirudh Mehta, Brahmdutta Raval and M. K. Mohan Maruga Raja

JNR, 2026, 283
DOI: 10.18311/jnr/2026/49938

Relaxation Dynamics in Dihydroxychalcones: Insights from Ultrafast Spectroscopy and Quantum Computations

Simin Roshan, Michael Hymas, Matthieu M. Mention, Florent Allais, Vasilios G. Stavros and Reza Omidyan

ACS Phys. Chem Au, 2025, 5, 628
DOI: 10.1021/acsphyschemau.5c00057

Regiospecific biosynthesis of natural sweetener hesperetin dihydrochalcone from phloretin via designed dual-enzyme whole-cell cascade

Shuping Xu, Ruobin Sun, Wenhao Deng, Pengcheng Chen, Xinyu Fan, Ji Ma, Yanzi Sun, Dan Wu and Pu Zheng

Bioresource Technology, 2026, 446, 134194
DOI: 10.1016/j.biortech.2026.134194

Bio-extracted chitosan-functionalized Mg–Al bimetallic as an innovative hybrid catalyst for green and sustainable synthesis of bioactive molecules with medicinal potential

Jamal Houssaini, M’hamed EL Bouhi, Hamid Ziyat, Said Arhzaf, Mohammed Naciri Bennani and Mohammed Bouachrine

Journal of Organometallic Chemistry, 2026, 1050, 124090
DOI: 10.1016/j.jorganchem.2026.124090

A Low Temperature Fluorescence Study of a 4-Dimethylamino-2′-Hydroxy Chalcone: From Solvent Matrix to Crystalline State

Brian Corbin, Agampodi Dimagi Dasunika De Zoysa, Margaret Hilliker and Yi Pang

Photochem, 2026, 6, 19
DOI: 10.3390/photochem6020019

Nitrochalcones: Pharmacological Activities and Therapeutic Potential

Erika Madeleyne Ramos-Rivera, Nancy Romero-Ceronio, Oswaldo Hernández-Abreu, Cuauhtémoc Alvarado-Sánchez, Quirino Torres-Sauret, Manuel Velasco-Ximello, Heidi Beatriz Montejo-Méndez, Jorge Cortez-Elizalde, Nadia Landero-Valenzuela, Luis Fernando Roa de la Fuente, Rosalía Torralba Sánchez, Lucero Vázquez-Cruz, Miguel Ángel Vilchis-Reyes and Alam Yair Hidalgo

IJMS, 2026, 27, 2711
DOI: 10.3390/ijms27062711

Naringenin, a unique flavonoid present in Dillenia indica L., 1759, reveals potent anti-leishmanial properties- an in silico and in vitro study

Vandita Verma, Ishita Bhattacharya, Nibedita Pyne and Santanu Paul

Pharmacological Research - Natural Products, 2025, 9, 100409
DOI: 10.1016/j.prenap.2025.100409

Response surface methodology optimization of microwave and pulsed electric field pretreatments for enhancing bioactive properties of licorice stem powder

Abdelrahman Aly Mohamed Eleter, Elfadil E. Babiker, Fahad Y. Al Juhaimi, Mahmoud Younis, Hesham Al-Quh and Isam A. Mohamed Ahmed

LWT, 2025, 230, 118282
DOI: 10.1016/j.lwt.2025.118282

Recent developments in synthesis and antimalarial activities of chalcone hybrids

Ravindar Lekkala, Revathi Lekkala, Fei Wen Cheong, Nurul Izzaty Hassan and Yee Ling Lau

Bioorganic & Medicinal Chemistry, 2026, 133, 118512
DOI: 10.1016/j.bmc.2025.118512