Roles of S100A8, S100A9 and S100A12 in infection, inflammation and immunity

Pengpeng Xia, Xingduo Ji, Li Yan, Siqi Lian, Ziyue Chen and Yi Luo

Immunology, 2024, 171, 365
DOI: 10.1111/imm.13722

Neutrophils from Protection to Pathogenesis in Tuberculosis

Hussain Beig and Amit Singh

ACS Infect. Dis., 2025, 11, 2926
DOI: 10.1021/acsinfecdis.5c00096

The Role of Fecal Calprotectin in Patients with Systemic Sclerosis and Small Intestinal Bacterial Overgrowth (SIBO)

Beata Polkowska-Pruszyńska, Agnieszka Gerkowicz, Karol Rawicz-Pruszyński and Dorota Krasowska

Diagnostics, 2020, 10, 587
DOI: 10.3390/diagnostics10080587

Multi-metal nutrient restriction and crosstalk in metallostasis systems in microbial pathogens

Matthew R Jordan, Jiefei Wang, Daiana A Capdevila and David P Giedroc

Current Opinion in Microbiology, 2020, 55, 17
DOI: 10.1016/j.mib.2020.01.010

Molecular Evolution of Transition Metal Bioavailability at the Host–Pathogen Interface

Giuliano T. Antelo, Alejandro J. Vila, David P. Giedroc and Daiana A. Capdevila

Trends in Microbiology, 2021, 29, 441
DOI: 10.1016/j.tim.2020.08.001

Microneedle array delivery of Yersinia pestis recapitulates bubonic plague

Sarah L. Price, Robert S. Oakes, Rodrigo J. Gonzalez, Camilla Edwards, Amanda Brady, Jennifer K. DeMarco, Ulrich H. von Andrian, Christopher M. Jewell and Matthew B. Lawrenz

iScience, 2024, 27, 108600
DOI: 10.1016/j.isci.2023.108600

The Innate Immune Protein Calprotectin Interacts With and Encases Biofilm Communities of Pseudomonas aeruginosa and Staphylococcus aureus

Jiwasmika Baishya, Jake A. Everett, Walter J. Chazin, Kendra P. Rumbaugh and Catherine A. Wakeman

Front. Cell. Infect. Microbiol., 2022, 12
DOI: 10.3389/fcimb.2022.898796

Calprotectin blockade inhibits long-term vascular pathology following peritoneal dialysis-associated bacterial infection

Esra Cetin, Morgane Mazzarino, Guadalupe T. González-Mateo, Valeria Kopytina, Soma Meran, Donald Fraser, Manuel López-Cabrera, Mario O. Labéta and Anne-Catherine Raby

Front. Cell. Infect. Microbiol., 2023, 13
DOI: 10.3389/fcimb.2023.1285193

Calprotectin elicits aberrant iron starvation responses in Pseudomonas aeruginosa under anaerobic conditions

Jacob M. Weiner, Wei Hao Lee, Elizabeth M. Nolan, Amanda G. Oglesby and George O'Toole

J Bacteriol, 2025, 207
DOI: 10.1128/jb.00029-25

Calprotectin, a Promising Serological Biomarker for the Early Diagnosis of Superinfections with Multidrug-Resistant Bacteria in Patients with COVID-19

Dennis Keller, Patricia Mester, Ulrich Räth, Sabrina Krautbauer, Stephan Schmid, Verena Greifenberg, Martina Müller, Claudia Kunst, Christa Buechler and Vlad Pavel

IJMS, 2024, 25, 9294
DOI: 10.3390/ijms25179294

Calprotectin-mediated survival of Staphylococcus aureus in coculture with Pseudomonas aeruginosa occurs without nutrient metal sequestration

Wei H. Lee, Emily M. Zygiel, Celis H. Lee, Amanda G. Oglesby, Elizabeth M. Nolan and Alejandro J. Vila

mBio, 2025, 16
DOI: 10.1128/mbio.03846-24

The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa

Emily M. Zygiel, Cassandra E. Nelson, Luke K. Brewer, Amanda G. Oglesby-Sherrouse and Elizabeth M. Nolan

Journal of Biological Chemistry, 2019, 294, 3549
DOI: 10.1074/jbc.RA118.006819

Bacterial Responses to Iron Withholding by Calprotectin

Adunoluwa O. Obisesan, Emily M. Zygiel and Elizabeth M. Nolan

Biochemistry, 2021, 60, 3337
DOI: 10.1021/acs.biochem.1c00572

An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats

Alexandra N. Myers, Sara D. Lawhon, Alison B. Diesel, Charles W. Bradley, Aline Rodrigues Hoffmann, William J. Murphy and Leigh Anne Clark

PLoS Genet, 2022, 18, e1010062
DOI: 10.1371/journal.pgen.1010062

Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics

Maximillian K. Osterberg, Daniel W. Bak, Claudia Andreini, Minyong Kim, Jeanette M. Critchlow, Jonathan C. Trinidad, Peter V. Cornish, Tae Akizuki, Walter J. Chazin, Eric P. Skaar, Eranthie Weerapana and David P. Giedroc

ACS Chem. Biol., 2025, 20, 2808
DOI: 10.1021/acschembio.5c00753

Yersiniabactin contributes to overcoming zinc restriction during Yersinia pestis infection of mammalian and insect hosts

Sarah L. Price, Viveka Vadyvaloo, Jennifer K. DeMarco, Amanda Brady, Phoenix A. Gray, Thomas E. Kehl-Fie, Sylvie Garneau-Tsodikova, Robert D. Perry and Matthew B. Lawrenz

Proc. Natl. Acad. Sci. U.S.A., 2021, 118
DOI: 10.1073/pnas.2104073118

Mechanisms and Therapeutic Potential of Nutritional Immunity

Charles Egede Ugwu, Olalekan Chris Akinsulie, Toyin Florence Ayandokun, Favour Akinfemi Ajibade, Sammuel Shahzad, Victor Ayodele Aliyu, Moyinoluwa Joshua Oladoye, Ibrahim Idris, Kingsley Ogochukwu Obasi, Joel Kosisochukwu Edeh, Al-Amin Adebare Olojede, Chizaram Blessing Ukauwa, Muhammad Ipoola Adeyemi, Charity Chinonso Ugwu and Lilian Chizobam Ugorji

Pathogens, 2026, 15, 176
DOI: 10.3390/pathogens15020176

Forging biofilms: metal-induced microbial responses in biofilm formation

Sarah L. Price, Eric P. Skaar and Mohamed Y. El-Naggar

J Bacteriol, 2025, 207
DOI: 10.1128/jb.00247-25

Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9

Joseph L Harman, Andrea N Loes, Gus D Warren, Maureen C Heaphy, Kirsten J Lampi and Michael J Harms

eLife, 2020, 9
DOI: 10.7554/eLife.54100

Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatment Lyme Disease Syndromes

Felipe C. Cabello, Monica E. Embers, Stuart A. Newman, Henry P. Godfrey, Steven J. Norris and Danielle A. Garsin

mBio, 2022, 13
DOI: 10.1128/mbio.03440-21

The C‐terminal extension of calprotectin mediates zinc chelation and modulates Staphylococcus aureus biomass accumulation

Yasiru R. Perera, Kyle T. Enriquez, Aslin Rodriguez, Velia Garcia, Tae Akizuki, Anais Naretto, Melumo Togashi, Ryan Guillen, Eric P. Skaar and Walter J. Chazin

Protein Science, 2025, 34
DOI: 10.1002/pro.70294

Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin

Emily M. Zygiel and Elizabeth M. Nolan

Acc. Chem. Res., 2019, 52, 2301
DOI: 10.1021/acs.accounts.9b00250

Metal Sequestration and Antimicrobial Activity of Human Calprotectin Are pH-Dependent

Tomer Rosen and Elizabeth M. Nolan

Biochemistry, 2020, 59, 2468
DOI: 10.1021/acs.biochem.0c00359