Themed collection Journal of Materials Chemistry B Recent Review Articles
Breakthrough in Cancer Therapy: Lutetium Texaphyrin-Celecoxib Conjugate for Immune and Photodynamic Treatment
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB02019G
A novel surface-enhanced Raman based molecular identification platform for multiplexed and highly accurate clinical diagnosis of viral diseases
Schematic illustration of the E-NoM platform. The workflow for the simultaneous detection of four viral antigens during the infection process.
J. Mater. Chem. B, 2024,12, 7461-7462
https://doi.org/10.1039/D4TB00796D
In vivo photopharmacological inhibition of hippocampal activity via multimodal probes – perspective and opening steps on experimental and computational challenges
A new perspective for the study/treatment of neurological conditions using in vivo photopharmacology is presented, including initial experimental and computational data.
J. Mater. Chem. B, 2024,12, 9894-9904
https://doi.org/10.1039/D4TB01117A
Colloidal photonic crystals towards biological applications
Colloidal photonic crystals exhibit unique properties that make them ideal for biological applications. This perspective summarizes the primary properties, the strategies, and recent advancements for biological applications.
J. Mater. Chem. B, 2024,12, 8488-8504
https://doi.org/10.1039/D4TB01325E
Steric protection of near-infrared fluorescent dyes for enhanced bioimaging
Steric protection of a long-wavelength dye, by covalent steric appendage or non-covalent encapsulation, produces enhanced photostability, increased fluorescence brightness, decreased self-aggregation, and superior pharmacokinetic profile.
J. Mater. Chem. B, 2024,12, 8310-8320
https://doi.org/10.1039/D4TB01281J
Sculpturing the future of water-soluble cyclodextrin branched polymers in pharmaceutical applications
Versatile water-soluble cyclodextrin polymers can be easily prepared from naturally occurring monomers upon polycondensation in the presence of crosslinking agents. We consider their potential use in combination therapies and the hurdles faced.
J. Mater. Chem. B, 2024,12, 7969-7976
https://doi.org/10.1039/D4TB01165A
Looking back, moving forward: protein corona of lipid nanoparticles
Intelligent delivery of lipid nanoparticles can be achieved through rational design of protein corona as a “troublemaker”.
J. Mater. Chem. B, 2024,12, 5573-5588
https://doi.org/10.1039/D4TB00186A
Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds
Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.
J. Mater. Chem. B, 2024,12, 2720-2736
https://doi.org/10.1039/D3TB02674D
Enzymatic micro/nanomotors in biomedicine: from single motors to swarms
Micro/nanomotor swarms propelled by diverse mechanisms.
J. Mater. Chem. B, 2024,12, 2711-2719
https://doi.org/10.1039/D3TB02457A
Intestinal retentive systems – recent advances and emerging approaches
Intestinal retentive devices (IRDs) are devices designed to anchor within the lumen of the intestines for long-term residence in the gastrointestinal tract.
J. Mater. Chem. B, 2024,12, 64-78
https://doi.org/10.1039/D3TB01842C
Recent advances in phototherapeutic nanosystems for oral cancer
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01919A
Dissolving Microneedles: Standing Out in Melanoma Treatment
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01142B
AI-driven precision subcellular navigation with fluorescent probes
AI-driven precision subcellular navigation with fluorescent probes.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01835D
Bioactive glass–polymer nanocomposites: a comprehensive review on unveiling their biomedical applications
A comprehensive overview of bioactive glass–polymer nanocomposites highlighting the various fabrication strategies, the materials involved and the major biomedical applications.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01525H
Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01930J
Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity
Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01907E
Engineering disease analyte response in peptide self-assembly
The need to enhance the precision and specificity of therapeutic nanocarriers has led to the development of nanoscale peptide assemblies capable of sensing and responding to disease-related analytes.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01860E
Surface engineering of Orthopedic implants for better clinical adoption
J. Mater. Chem. B, 2024, Accepted Manuscript
https://doi.org/10.1039/D4TB01563K
Piezoelectric materials for anti-infective bioapplications
This review summarizes recent advances in piezoelectric materials for anti-infective and regenerative therapies. It highlights antibacterial mechanisms and discusses their anti-infective bioapplications.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01589D
Protein nanopore-based sensors for public health analyte detection
High-throughput and label-free protein nanopore-based sensors with engineering strategies are extensively used to identify public health hazardous substances with single channel recording.
J. Mater. Chem. B, 2024,12, 9845-9862
https://doi.org/10.1039/D4TB01149J
The recent progress of bone regeneration materials containing EGCG
Bone regeneration materials combined with EGCG include natural polymer, synthetic polymer, bioceramic, metal, hydrogel and metal–EGCG networks. Currently, the above materials have been widely studied in the field of medicine.
J. Mater. Chem. B, 2024,12, 9835-9844
https://doi.org/10.1039/D4TB00604F
Recent development and applications of electrodeposition biocoatings on medical titanium for bone repair
Schematic diagram of the device, mechanism and biomedical application of electrodeposition for the preparation of bioactive coatings on the surface of titanium implants for bone repair.
J. Mater. Chem. B, 2024,12, 9863-9893
https://doi.org/10.1039/D4TB01081G
Nanomaterial combined engineered bacteria for intelligent tumor immunotherapy
Compared to traditional therapies, tumor immunotherapy has received a lot of attention and research focus due to its potential to activate both innate and adaptive immunity, cause low toxicity to normal tissue, and induce long-term immune activity.
J. Mater. Chem. B, 2024,12, 9795-9820
https://doi.org/10.1039/D4TB00741G
Immunologically effective biomaterials enhance immunotherapy of prostate cancer
Prostate cancer (PCa) is one of the most common malignant neoplasms affecting the male population.
J. Mater. Chem. B, 2024,12, 9821-9834
https://doi.org/10.1039/D3TB03044J
Advances in ionic liquid-based antimicrobial wound healing platforms
Wound infections, marked by the proliferation of microorganisms at surgical sites, necessitate the development of innovative wound dressings with potent bactericidal properties to curb microbial growth and prevent bacterial infiltration.
J. Mater. Chem. B, 2024,12, 9478-9507
https://doi.org/10.1039/D4TB00841C
Endocytosis: the match point of nanoparticle-based cancer therapy
Endocytosis efficiency is a prerequisite for the therapeutic efficacy of nanoparticle-based cancer therapy. This review elucidates the physicochemical design, anti-cancer effects and endocytic mechanism of multiple endocytosis-oriented nanoparticles.
J. Mater. Chem. B, 2024,12, 9435-9458
https://doi.org/10.1039/D4TB01227E
Immune response profiles induced by silk-based biomaterials: a journey from ‘immunogenicity’ towards ‘immuno-compatibility
The silk protein elicits ambivalent, both mild inflammatory and anti-inflammatory immune responses for biomedical applications that can be attributed to surface chemistry, protein conformation, source of origin, and association with other proteins.
J. Mater. Chem. B, 2024,12, 9508-9523
https://doi.org/10.1039/D4TB01231C
Biomaterials based on advanced oxidation processes in tooth whitening: fundamentals, progress, and models
Innovative tooth whitening strategies based on advanced oxidation processes.
J. Mater. Chem. B, 2024,12, 9459-9477
https://doi.org/10.1039/D4TB01311E
Metal–organic frameworks: potential synergies with cold atmospheric plasmas for cancer control
MOFs can act as cargo-carriers, nano-enzymes, and magnetic MOFs. CAPs, interacting with cell receptors to generate primary and secondary 1O2, may synergize with MOFs for oncotherapy via acting as cargos, substrates, and magnetic sensing agents.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00968A
Bioorthogonal chemistry-based prodrug strategies for enhanced biosafety in tumor treatments: current progress and challenges
Prodrugs, activated at the tumor site, offer targeted treatment but may still cause unintended cytotoxicity. This review explores the combination of bioorthogonal reactions with prodrug strategies to improve safety and efficacy.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01413H
Unlocking the potential of RGD-conjugated gold nanoparticles: a new frontier in targeted cancer therapy, imaging, and metastasis inhibition
The review highlights the potential of RGD-conjugated AuNPs in cancer diagnosis and treatment, including breast cancer. It emphasizes the need for further research to fully realize this technology’s potential and inspire future investigations.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00281D
Nanozymes in cancer immunotherapy: metabolic disruption and therapeutic synergy
The unique roles of nanozymes in enhancing immunotherapy through disrupting tumor metabolism and mediating combination therapies.
J. Mater. Chem. B, 2024,12, 9111-9143
https://doi.org/10.1039/D4TB00769G
Nanomaterial-based therapeutics for enhanced antifungal therapy
This review comprehensively explores the application of nanotechnology for antifungal therapy, particularly focusing on enhancing interaction with fungi, stimuli-responsive drug release in fungal infected tissues, and crossing biological barriers.
J. Mater. Chem. B, 2024,12, 9173-9198
https://doi.org/10.1039/D4TB01484G
Designing antibacterial materials through simulation and theory
To broaden the application of antibacterial materials in nanomedicine, understanding the complex mechanisms and inherent properties is crucial. This review summarizes the advancements in computational and theoretical research in this emerging field.
J. Mater. Chem. B, 2024,12, 9155-9172
https://doi.org/10.1039/D4TB01277A
A novel method for the diagnosis of atherosclerosis based on nanotechnology
The integration of nanotechnology and medicine is a significant trend in modern healthcare, with a particular focus on its utilization in atherosclerosis imaging, presenting immense potential for advancement.
J. Mater. Chem. B, 2024,12, 9144-9154
https://doi.org/10.1039/D4TB00900B
Application of advanced surface modification techniques in titanium-based implants: latest strategies for enhanced antibacterial properties and osseointegration
Several major surface modification technologies for Ti-based implants.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01714E
Alleviating hypoxia and oxidative stress for treatment of cardiovascular diseases: a biomaterials perspective
Advanced approaches to alleviate hypoxic and oxidative stress in cardiovascular diseases.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01126K
Tissue adhesives based on chitosan for biomedical applications
Chitosan bio-adhesives bond strongly with various biological tissues, such as skin, mucosa, and internal organs.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01362J
Atomically dispersed single-atom catalysts (SACs) and enzymes (SAzymes): synthesis and application in Alzheimer's disease detection
SAC & SAzymes, an innovative tool for early Alzheimer detection, effectively bridging traditional diagnostic methods with advanced technologies, enable highly sensitive and selective identification of biomarkers, enhancing diagnostic accuracy.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01293C
Prediction of aptamer affinity using an artificial intelligence approach
Aptamers are oligonucleotide sequences that can connect to particular target molecules, similar to monoclonal antibodies.
J. Mater. Chem. B, 2024,12, 8825-8842
https://doi.org/10.1039/D4TB00909F
Nanoparticles constructed from natural polyphenols are used in acute kidney injury
Acute kidney injury (AKI) is a severe clinical syndrome characterized by rapid deterioration of renal function caused by a variety of pathogeneses.
J. Mater. Chem. B, 2024,12, 8883-8896
https://doi.org/10.1039/D4TB00837E
Decellularized extracellular matrix-based bioengineered 3D breast cancer scaffolds for personalized therapy and drug screening
Bioengineered 3D breast cancer model using responsive decellularized scaffold.
J. Mater. Chem. B, 2024,12, 8843-8867
https://doi.org/10.1039/D4TB00680A
Dual-/multi-organelle-targeted AIE probes associated with oxidative stress for biomedical applications
This review summarizes the recent advancements in biomedical applications of dual-/multi-organelle-targeted aggregation-induced emission (AIE) probes, focusing on their in situ induction of oxidative stress.
J. Mater. Chem. B, 2024,12, 8812-8824
https://doi.org/10.1039/D4TB01440E
Exogenous MSC based tissue regeneration: a review of immuno-protection strategies from biomaterial scaffolds
Mesenchymal stem cell (MSC)-based tissue engineering holds great potential for regenerative medicine as a means of replacing damaged or lost tissues to restore their structure and function.
J. Mater. Chem. B, 2024,12, 8868-8882
https://doi.org/10.1039/D4TB00778F
Advancements in DNA computing: exploring DNA logic systems and their biomedical applications
DNA computing is a key molecular method in biological analysis. This review highlights advancements in DNA logic systems, material innovations, and applications in imaging, diagnosis, and treatment, addressing challenges and future directions.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB00936C
Recent advances in fluorescent probes for fatty liver imaging by detecting lipid droplets
This review summarizes various probes for imaging LDs in the fatty liver process using different excitation imaging modes and emission wavelengths, as well as analyzing the achievements, challenges and future development trends in this field.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01741B
Exploring enzyme-immobilized MOFs and their application potential: biosensing, biocatalysis, targeted drug delivery and cancer therapy
This review presents the various enzyme immobilization techniques and highlight their application in biosensing, bio-catalysis, drug delivery, and cancer therapy.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01556H
Recent advances in sodium alginate-based dressings for targeted drug delivery in the context of diabetic wound healing
This review covers advanced diabetic wound dressing materials, including chitosan–alginate hydrogels, nanofiber mats, and core–shell nanostructures, highlighting the role of nanotechnology and biomimetic scaffolds in improving healing outcomes.
J. Mater. Chem. B, 2024, Advance Article
https://doi.org/10.1039/D4TB01049C
Methods to achieve tissue-mimetic physicochemical properties in hydrogels for regenerative medicine and tissue engineering
Hydrogels are limited by their inability to recapitulate native extracellular physicochemical properties. Current efforts using advanced materials science and engineering methods seek to form hydrogels with physiologically-relevant properties.
J. Mater. Chem. B, 2024,12, 8505-8522
https://doi.org/10.1039/D4TB00716F
Application of metal–organic framework materials in regenerative medicine
Applications of nano-MOFs in bone tissue engineering, wound healing, and others, including periodontitis, tendon repair, nerve repair, and cardiovascular disease. Created with BioRender.com.
J. Mater. Chem. B, 2024,12, 8543-8576
https://doi.org/10.1039/D4TB00226A
Wearable and implantable biosensors: mechanisms and applications in closed-loop therapeutic systems
Biosensors integrated into closed-loop systems provide patient-specific adaptive therapies. These advanced devices have significant potential for managing chronic conditions by continuously adjusting therapeutic regimens based on physiological data.
J. Mater. Chem. B, 2024,12, 8577-8604
https://doi.org/10.1039/D4TB00782D
Research progress on biodegradable magnesium phosphate ceramics in orthopaedic applications
Magnesium phosphate bioceramics in bone tissue engineering.
J. Mater. Chem. B, 2024,12, 8605-8615
https://doi.org/10.1039/D4TB01123F
Ion-sensitive field effect transistor biosensors for biomarker detection: current progress and challenges
The ISFET is a label-free, miniaturized, sensitive, and rapid-response sensor for disease screening and monitoring. This review covers its structure, recent researches, challenges, solutions, and future prospects for biomarker measurement.
J. Mater. Chem. B, 2024,12, 8523-8542
https://doi.org/10.1039/D4TB00719K
A comprehensive review on the role of strontium in biodegradable metals
The role of strontium in biodegradable metals.
J. Mater. Chem. B, 2024,12, 8267-8284
https://doi.org/10.1039/D4TB00779D
Recent advances on nanomaterial-based glutathione sensors
This review comprehensively covers a wide range of nanomaterial categories, including the fabrication of both chemo- and biosensors, detection methodologies, detection mechanisms, and the applied biological environments for glutathione detection.
J. Mater. Chem. B, 2024,12, 8285-8309
https://doi.org/10.1039/D4TB01114G
Integrated design and application of stimuli-responsive metal–organic frameworks in biomedicine: current status and future perspectives
Various stimuli-responsive MOFs require different triggers and exhibit diverse applications, necessitating the development of biomedical application strategies tailored to specific environments.
J. Mater. Chem. B, 2024,12, 8235-8266
https://doi.org/10.1039/D4TB00768A
Light-responsive functional nanomaterials as pioneering therapeutics: a paradigm shift to combat age-related disorders
Aging leads to diseases marked by plaque formation, increased senescent cells, and compromised body organ systems. Light-responsive nanomaterials offer a promising therapeutic approach to address the various aspects of age-related pathologies.
J. Mater. Chem. B, 2024,12, 8212-8234
https://doi.org/10.1039/D4TB00578C
Hydrogels: a promising therapeutic platform for inflammatory skin diseases treatment
Hydrogels revolutionize treating chronic skin diseases by enhancing drug delivery and reducing side effects. This review explores hydrogel design, drug integration, and clinical trials, highlighting their potential to improve efficacy and safety.
J. Mater. Chem. B, 2024,12, 8007-8032
https://doi.org/10.1039/D4TB00887A
Aggregable gold nanoparticles for cancer photothermal therapy
Photothermal therapy (PTT) is an important non-invasive cancer treatment method.
J. Mater. Chem. B, 2024,12, 8048-8061
https://doi.org/10.1039/D4TB00403E
Application of a calcium and phosphorus biomineralization strategy in tooth repair: a systematic review
This review summarizes the mechanisms and commonalities of biomineralization and discusses the advancements in dental biomineralization research, guided by insights into calcium and phosphorus mineral biomineralization.
J. Mater. Chem. B, 2024,12, 8033-8047
https://doi.org/10.1039/D4TB00867G
Innovative approaches to wound healing: insights into interactive dressings and future directions
The objective of this review is to provide an up-to-date and all-encompassing account of the recent advancements in the domain of interactive wound dressings.
J. Mater. Chem. B, 2024,12, 7977-8006
https://doi.org/10.1039/D3TB02912C
Biomaterials for non-invasive trans-tympanic drug delivery: requirements, recent advances and perspectives
The practice of non-invasive trans-tympanic delivery faces multi-dimensional challenges. Suitable formulation for administration, permeability of the tympanic membrane, pharmacokinetics in middle and inner ear should be considered in design.
J. Mater. Chem. B, 2024,12, 7787-7813
https://doi.org/10.1039/D4TB00676C
Nanomaterials revolutionize biosensing: 0D–3D designs for ultrasensitive detection of microorganisms and viruses
Introducing nanomaterials into biosensors improves the performance of biosensors for faster and more accurate detection of microorganisms and viruses.
J. Mater. Chem. B, 2024,12, 7760-7786
https://doi.org/10.1039/D4TB01077A
Building in vitro models for mechanistic understanding of liver regeneration in chronic liver diseases
The figure shows how impaired regeneration fuels CLD progression. It depicts how 3D bioprinted models can overcome the limitations of animal models and clinical/histopathological data, and provide mechanistic insights into liver regeneration.
J. Mater. Chem. B, 2024,12, 7669-7691
https://doi.org/10.1039/D4TB00738G
Nanocellulose-based hydrogels as versatile materials with interesting functional properties for tissue engineering applications
Tissue engineering has emerged as a remarkable field aiming to repair or replace damaged tissues through the use of biomimetic constructs.
J. Mater. Chem. B, 2024,12, 7692-7759
https://doi.org/10.1039/D4TB00397G
Chitosan-based biomaterials promote bone regeneration by regulating macrophage fate
The development of various osteogenic biomaterials has not only promoted the development of bone tissue engineering but also provided more possibilities for bone defect repair.
J. Mater. Chem. B, 2024,12, 7480-7496
https://doi.org/10.1039/D3TB02563B
Recent advances of functional modules for tooth regeneration
The use of 3D bioprinting, cell sheet technology, electrostatic droplet technology, and electrospinning technology to generate functional tooth modules represents an emerging and promising approach in dental tissue engineering.
J. Mater. Chem. B, 2024,12, 7497-7518
https://doi.org/10.1039/D4TB01027B
Magneto-responsive biocomposites in wound healing: from characteristics to functions
Schematic illustrations of the pathways through which magneto-responsive biocomposites promote wound healing.
J. Mater. Chem. B, 2024,12, 7463-7479
https://doi.org/10.1039/D4TB00743C
Microfluidic-based cardiovascular systems for advanced study of atherosclerosis
This review summarizes the latest advancements in microfluidic-based cardiovascular systems for AS research, encompassing investigations of the underlying pathogenesis and development of diagnostic methods for efficient therapeutic treatments.
J. Mater. Chem. B, 2024,12, 7225-7245
https://doi.org/10.1039/D4TB00756E
DNA functionalized programmable hybrid biomaterials for targeted multiplexed applications
With the advent of DNA nanotechnology, DNA-based biomaterials have emerged as a unique class of materials at the center of various biological advances.
J. Mater. Chem. B, 2024,12, 7267-7291
https://doi.org/10.1039/D4TB00287C
About this collection
This collection contains recent Review-type articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine. New articles will be added to this collection as soon as possible after publication.